Research Topics
| Georg NorthoffSummaryAffiliation: University of Ottawa Country: Canada Publications
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Detail Information
Publications
Rest-stimulus interaction in the brain: a reviewGeorg Northoff
Institute of Mental Health Research, University of Ottawa, Ottawa, ON K1Z 7K4, Canada
Trends Neurosci 33:277-84. 2010..We conclude that a better understanding of the rest-stimulus interaction is likely to be crucial to the elucidation of the brain's contribution to mental states...- Is our self nothing but reward?Georg Northoff
Mind, Brain Imaging and Neuroethics Unit, Institute of Mental Health Research, Royal Ottawa Health Care Group, University of Ottawa, Ontario, Canada
Biol Psychiatry 69:1019-25. 2011..This interaction may help to fill in some of the missing pieces regarding reward-related processing, as well as illuminate how brain function can bring forward the philosophical concept and psychological reality of self... - Humans, brains, and their environment: marriage between neuroscience and anthropology?Georg Northoff
Institute of Mental Health Research, University of Ottawa, Ottawa K1Z 7K4, Canada
Neuron 65:748-51. 2010..However, rather than being incorporated into neuroscience, anthropology may be considered complementary, and a marriage of the two disciplines can provide deep insight into these fundamental questions... - The brain and its resting state activity--experimental and methodological implicationsGeorg Northoff
Mind, Brain Imaging and Neuroethics Research Unit, Institute of Mental Health Research, University of Ottawa, Canada
Prog Neurobiol 92:593-600. 2010..This may also shed new light on some hitherto unresolved questions like the neuroscientific mechanisms underlying consciousness and psychiatric disorders... - Brain imaging of the self--conceptual, anatomical and methodological issuesGeorg Northoff
Mind, Brain Imaging and Neuroethics, University of Ottawa Institute of Mental Health Research IMHR, 1145 Carling Avenue Ottawa, ON, Canada K1Z 7K4
Conscious Cogn 20:52-63. 2011..Modifications of both conceptual and anatomical dimensions will allow an empirically more plausible account of the relationship between brain and self... - How can the brain's resting state activity generate hallucinations? A 'resting state hypothesis' of auditory verbal hallucinationsGeorg Northoff
Mind, Brain Imaging and Neuroethics, Institute of Mental Health Research IMHR, 1145 Carling Avenue, Ottawa, ON K1Z 7K4, Canada
Schizophr Res 127:202-14. 2011..We discuss evidence in favour of our 'resting state hypothesis' and show its correspondence with phenomenological accounts... - The 'resting-state hypothesis' of major depressive disorder-a translational subcortical-cortical framework for a system disorderGeorg Northoff
University of Ottawa Institue of Mental Health Research, University of Hangzhou, China
Neurosci Biobehav Rev 35:1929-45. 2011.... - Involvement of glutamate in rest-stimulus interaction between perigenual and supragenual anterior cingulate cortex: a combined fMRI-MRS studyNiall W Duncan
Mind, Brain Imaging and Neuroethics, Institute of Mental Health Research, University of Ottawa, Ottawa, ON, Canada
Hum Brain Mapp 32:2172-82. 2011..This provides insight into the neuronal and biochemical mechanisms by means of which the resting state activity of the brain potentially impacts upon subsequent stimulus-induced activity... - How is informed consent related to emotions and empathy? An exploratory neuroethical investigationAlexander Supady
Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany
J Med Ethics 37:311-7. 2011..While cognitive functions have been shown to play a central role, the impact of empathy and emotions on subjects' decisions in informed consent remains unclear... - Glutamate concentration in the medial prefrontal cortex predicts resting-state cortical-subcortical functional connectivity in humansNiall W Duncan
Mind, Brain Imaging and Neuroethics Research Unit, University of Ottawa Institute of Mental Health Research, Ottawa, Canada Department of Biology, University of Carleton, Ottawa, Canada
PLoS ONE 8:e60312. 2013..These results are in agreement with existing results from animal studies and may have relevance for MDD and schizophrenia... 
GABA(A) receptors in visual and auditory cortex and neural activity changes during basic visual stimulationPengmin Qin
Mind, Brain Imaging and Neuroethics, University of Ottawa Institute of Mental Health Research Ottawa, ON, Canada
Front Hum Neurosci 6:337. 2012..These findings contribute to our understanding of the role of GABA(A) receptors in stimulus-induced neural activity in local regions and in inter-regional functional connectivity...- Common brain activations for painful and non-painful aversive stimuliDave J Hayes
Mind, Brain Imaging and Neuroethics Research Unit, Institute of Mental Health Research, University of Ottawa, 1145 Carling Avenue, Ottawa, K1Z 7K4, Canada
BMC Neurosci 13:60. 2012..To help clarify this issue, this report used a cross-species translational approach in humans (i.e. meta-analysis) and rodents (i.e. systematic review of functional neuroanatomy)... - Is there a core neural network in empathy? An fMRI based quantitative meta-analysisYan Fan
Institute of Mental Health Research, University of Ottawa, Ottawa, Canada
Neurosci Biobehav Rev 35:903-11. 2011..It was concluded that the dACC-aMCC-SMA and bilateral insula can be considered as forming a core network in empathy, and that cognitive-evaluative and affective-perceptual empathy can be distinguished at the level of regional activation... - How is our self related to midline regions and the default-mode network?Pengmin Qin
Mind, Brain Imaging and Neuroethics, Institute of Mental Health Research, 1145 Carling Avenue Ottawa, ON, Canada K1Z 7K4
Neuroimage 57:1221-33. 2011..Taken together, our data suggest that our sense of self may result from a specific kind of interaction between resting state activity and stimulus-induced activity, i.e., rest-stimulus interaction, within the midline regions... - Neuroimaging in pedophiliaChristine Wiebking
Mind, Brain Imaging and Neuroethics, Royal Ottawa Healthcare, Institute of Mental Health Research, Ottawa, Canada
Curr Psychiatry Rep 15:351. 2013.... - Overview of potential procedural and participant-related confounds for neuroimaging of the resting stateNiall W Duncan
Mind, Brain Imaging and Neuroethics Research Unit, University of Ottawa Institute of Mental Health Research, Ottawa, Ont
J Psychiatry Neurosci 38:84-96. 2013..A particular theme that emerges from the overview is the range of systematic differences between types of study groups (e.g., between patients and controls) that may influence resting-state study results... - Distinction between Externally vs. Internally Guided Decision-Making: Operational Differences, Meta-Analytical Comparisons and Their Theoretical ImplicationsTakashi Nakao
Mind, Brain Imaging and Neuroethics, Institute of Mental Health Research, Royal Ottawa Health Care Group, University of Ottawa Ottawa, ON, Canada
Front Neurosci 6:31. 2012..Finally, based on the review and results of the meta-analysis, we discuss the differences and relations between decision-making of these two types in terms of their operational, neuronal, and theoretical characteristics... - Identifying a network of brain regions involved in aversion-related processing: a cross-species translational investigationDave J Hayes
Mind, Brain Imaging and Neuroethics Research Unit, Institute of Mental Health Research, University of Ottawa Ottawa, ON, Canada
Front Integr Neurosci 5:49. 2011..This not only contributes to our understanding of the trans-species neural correlates of aversion but may also carry important implications for psychiatric disorders where abnormal aversive behavior can often be observed... - Dissociation between anterior and posterior cortical regions during self-specificity and familiarity: a combined fMRI-meta-analytic studyPengmin Qin
Laboratory for Higher Brain Function, Institute of Psychology, Chinese Academy of Sciences, Beijing, China
Hum Brain Mapp 33:154-64. 2012..Finally, the distinction between anterior and posterior regions for self and familiarity was confirmed by meta-analytic data. This study demonstrates a clear anterior-posterior cortical partition between self-specificity and familiarity... - What is neuroethics? Empirical and theoretical neuroethicsGeorg Northoff
Canada Research Chair for Mind, Brain and Neuroethics, Michael Smith Chair for Neuroscience and Mental Health, Institute of Mental Health Research, University of Ottawa, Ottawa, Ontario, Canada
Curr Opin Psychiatry 22:565-9. 2009..In contrast, theoretical and methodological considerations have rather been neglected and thus what may be called theoretical neuroethics...