E T C Ngan

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. doi request reprint Dual-stream modulation failure: a novel hypothesis for the formation and maintenance of delusions in schizophrenia
    William J Speechley
    Department of Psychiatry, The University of British Columbia, 2C1 2255 Westbrook Mall, Vancouver, BC, Canada V6T 2A1
    Med Hypotheses 70:1210-4. 2008
  2. pmc Immediate and delayed effects of risperidone on cerebral metabolism in neuroleptic naïve schizophrenic patients: correlations with symptom change
    E T C Ngan
    Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC, Canada
    J Neurol Neurosurg Psychiatry 72:106-10. 2002
  3. ncbi request reprint Abnormal processing of speech during oddball target detection in schizophrenia
    Elton T C Ngan
    Department of Psychiatry, University of British Columbia, Vancouver, Canada
    Neuroimage 20:889-97. 2003
  4. doi request reprint A failure of conflict to modulate dual-stream processing may underlie the formation and maintenance of delusions
    W J Speechley
    Department of Psychiatry, The University of British Columbia, Vancouver B C, Canada
    Eur Psychiatry 25:80-6. 2010
  5. ncbi request reprint Changes in distributed neural circuitry function in patients with first-episode schizophrenia
    A Mendrek
    Department of Psychiatry, University of Montreal, Centre de Recherche Fernand Seguin, 7331 Hochelaga, Montreal, Quebec H1N 3V2, Canada
    Br J Psychiatry 185:205-14. 2004
  6. ncbi request reprint Decreased encoding efficiency in schizophrenia
    Tara A Cairo
    Department of Research, Riverview Hospital, Coquitlam, Canada
    Biol Psychiatry 59:740-6. 2006
  7. ncbi request reprint Abnormal function of the brain system supporting motivated attention in medicated patients with schizophrenia: an fMRI study
    Peter F Liddle
    Department of Psychiatry, University of British Columbia, Vancouver BC, Canada
    Psychol Med 36:1097-108. 2006
  8. ncbi request reprint Temporo-prefrontal coordination increases when semantic associations are strongly encoded
    Todd S Woodward
    Department of Research, Riverview Hospital, Canada
    Neuropsychologia 44:2308-14. 2006
  9. ncbi request reprint Do you hear what I hear? Neural correlates of thought disorder during listening to speech in schizophrenia
    Sara Weinstein
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    Schizophr Res 86:130-7. 2006
  10. ncbi request reprint Brain activation mediates the association between structural abnormality and symptom severity in schizophrenia
    Sara Weinstein
    Department of Psychiatry, University of British Columbia, 2C1 2255 Wesbrook Mall, Vancouver BC, Canada V6T 2A1
    Neuroimage 36:188-93. 2007

Detail Information

Publications19

  1. doi request reprint Dual-stream modulation failure: a novel hypothesis for the formation and maintenance of delusions in schizophrenia
    William J Speechley
    Department of Psychiatry, The University of British Columbia, 2C1 2255 Westbrook Mall, Vancouver, BC, Canada V6T 2A1
    Med Hypotheses 70:1210-4. 2008
    ..Specifically, we suggest that delusions are the result of a failure to reconcile the two streams due to both a failure of conflict to bias decision-making towards Stream 2 and an accentuated emotional bias towards Stream 1...
  2. pmc Immediate and delayed effects of risperidone on cerebral metabolism in neuroleptic naïve schizophrenic patients: correlations with symptom change
    E T C Ngan
    Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC, Canada
    J Neurol Neurosurg Psychiatry 72:106-10. 2002
    ..The temporal and regional relation between changes in metabolism and symptom improvement after treatment with risperidone was studied in eight previously unmedicated schizophrenic patients...
  3. ncbi request reprint Abnormal processing of speech during oddball target detection in schizophrenia
    Elton T C Ngan
    Department of Psychiatry, University of British Columbia, Vancouver, Canada
    Neuroimage 20:889-97. 2003
    ....
  4. doi request reprint A failure of conflict to modulate dual-stream processing may underlie the formation and maintenance of delusions
    W J Speechley
    Department of Psychiatry, The University of British Columbia, Vancouver B C, Canada
    Eur Psychiatry 25:80-6. 2010
    ..In delusional schizophrenia patients, a failure of conflict to modulate decision-making towards Stream 2 may reduce the influence of contradictory evidence, resulting in a failure to correct erroneous beliefs...
  5. ncbi request reprint Changes in distributed neural circuitry function in patients with first-episode schizophrenia
    A Mendrek
    Department of Psychiatry, University of Montreal, Centre de Recherche Fernand Seguin, 7331 Hochelaga, Montreal, Quebec H1N 3V2, Canada
    Br J Psychiatry 185:205-14. 2004
    ..A number of functional brain abnormalities have been reported in schizophrenia, but it remains to be determined which of them represent trait and state markers of the illness...
  6. ncbi request reprint Decreased encoding efficiency in schizophrenia
    Tara A Cairo
    Department of Research, Riverview Hospital, Coquitlam, Canada
    Biol Psychiatry 59:740-6. 2006
    ..Working memory deficits are a cardinal feature of schizophrenia that contribute to social and occupational dysfunction...
  7. ncbi request reprint Abnormal function of the brain system supporting motivated attention in medicated patients with schizophrenia: an fMRI study
    Peter F Liddle
    Department of Psychiatry, University of British Columbia, Vancouver BC, Canada
    Psychol Med 36:1097-108. 2006
    ..Patients with schizophrenia have an impaired ability to generate activity that is appropriate to current circumstances and goals...
  8. ncbi request reprint Temporo-prefrontal coordination increases when semantic associations are strongly encoded
    Todd S Woodward
    Department of Research, Riverview Hospital, Canada
    Neuropsychologia 44:2308-14. 2006
    ..These results suggest that formation of relational semantic associations that lead to strongly encoded episodes requires increased coordination of the left MTL-left PFC neural pathway...
  9. ncbi request reprint Do you hear what I hear? Neural correlates of thought disorder during listening to speech in schizophrenia
    Sara Weinstein
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    Schizophr Res 86:130-7. 2006
    ..As receptive language is spared in thought disorder, we propose that the increase in activation reflects compensatory processing allowing for normal performance...
  10. ncbi request reprint Brain activation mediates the association between structural abnormality and symptom severity in schizophrenia
    Sara Weinstein
    Department of Psychiatry, University of British Columbia, 2C1 2255 Wesbrook Mall, Vancouver BC, Canada V6T 2A1
    Neuroimage 36:188-93. 2007
    ....
  11. ncbi request reprint Processing efficiency of a verbal working memory system is modulated by amphetamine: an fMRI investigation
    Christine M Tipper
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada, V6T 1Z4
    Psychopharmacology (Berl) 180:634-43. 2005
    ..We directly tested this possibility with human participants by varying amphetamine dosage and measuring the efficiency of cortical processing in brain regions associated with working memory...
  12. ncbi request reprint Attention orienting dysfunction during salient novel stimulus processing in schizophrenia
    Kristin R Laurens
    Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, University of London, Box P023, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 75:159-71. 2005
    ..In addition, trend results suggest that patients experienced increased distraction by novel stimuli...
  13. ncbi request reprint The influence of working memory load on phase specific patterns of cortical activity
    Tara A Cairo
    Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, British Columbia, Canada V6T 2A1
    Brain Res Cogn Brain Res 21:377-87. 2004
    ..The analysis strategies employed in this study could be used to further delineate the phases of WM that are most severely compromised in clinical populations with WM disturbances...
  14. pmc Immediate effects of risperidone on cerebral activity in healthy subjects: a comparison with subjects with first-episode schizophrenia
    Carol J Lane
    Department of Psychiatry, University of British Columbia, Vancouver, BC
    J Psychiatry Neurosci 29:30-7. 2004
    ....
  15. ncbi request reprint Rostral anterior cingulate cortex dysfunction during error processing in schizophrenia
    Kristin R Laurens
    Department of Psychiatry, University of British Columbia, Vancouver, Canada
    Brain 126:610-22. 2003
    ....
  16. ncbi request reprint Thought and Language Index: an instrument for assessing thought and language in schizophrenia
    Peter F Liddle
    University of British Columbia, Vancouver, BC, Canada
    Br J Psychiatry 181:326-30. 2002
    ..Subtle formal thought disorders are difficult to quantify. Their relationship to florid thought disorder is unknown...
  17. ncbi request reprint Short- and long-term changes in anterior cingulate activation during resolution of task-set competition
    Todd S Woodward
    Department of Research, Riverview Hospital, Coquitlam, Canada
    Brain Res 1068:161-9. 2006
    ....
  18. ncbi request reprint State dependent changes in error monitoring in schizophrenia
    Alan T Bates
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    J Psychiatr Res 38:347-56. 2004
    ....
  19. ncbi request reprint Signs and Symptoms of Psychotic Illness (SSPI): a rating scale
    Peter F Liddle
    Department of Psychiatry, University of British Columbia, Canada
    Br J Psychiatry 180:45-50. 2002
    ....