Research Topics
| D M NeedhamSummaryAffiliation: University of Toronto Country: Canada Publications
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Detail Information
Publications
A province-wide study of the association between hospital resource allocation and length of stayDale M Needham
University of Toronto, Toronto, Canada
Health Serv Manage Res 16:155-66. 2003..Future research should focus on exploring the nature of this relationship and the potential interdependencies among hospital services that cause this effect...
Study protocol: The Improving Care of Acute Lung Injury Patients (ICAP) studyDale M Needham
Johns Hopkins University, 5th Floor, 1830 East Monument Street, Baltimore, MD 21205, USA
Crit Care 10:R9. 2006....- Socio-economic, gender and health services factors affecting diagnostic delay for tuberculosis patients in urban ZambiaD M Needham
Internal Medicine Residency Program, University of Toronto, Toronto, Canada
Trop Med Int Health 6:256-9. 2001..Decentralization of public tuberculosis care and improved integration with private sector health providers may also reduce diagnostic delay... - A systematic review of the Charlson comorbidity index using Canadian administrative databases: a perspective on risk adjustment in critical care researchDale M Needham
Department of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
J Crit Care 20:12-9. 2005..Future research should focus on updating the Charlson index for recent changes in the prognosis of comorbid diseases and introduction of International Statistical Classification of Diseases, 10th Revision coding of discharge abstracts... - Studying outcomes of intensive care unit survivors: measuring exposures and outcomesDale M Needham
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Intensive Care Med 31:1153-60. 2005..There is little systematic guidance for measuring these outcomes and exposures within the ICU setting. As a result measurement methods are often variable and non-comparable across studies... - Toronto Critical Care Medicine Symposium, 18-20 October 2001, Canada: research breakthroughs are not enoughD Needham
University of Toronto, Toronto, Ontario, Canada
Crit Care 5:329-30. 2001..Furthermore, additional study is needed for an understanding of how physicians implement new research findings. Successful methods of enhancing the widespread adoption of new research require further study... - Pulmonary vs nonpulmonary sepsis and mortality in acute lung injuryJonathan E Sevransky
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Chest 134:534-8. 2008..Acute lung injury (ALI) is a frequent complication of sepsis. It is unclear if a pulmonary vs nonpulmonary source of sepsis affects mortality in patients with sepsis-induced ALI... - Intensive care unit hypoglycemia predicts depression during early recovery from acute lung injuryDavid W Dowdy
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Crit Care Med 36:2726-33. 2008..To evaluate the association between intensive care unit blood glucose levels and depression after acute lung injury... - Intensive care unit exposures for long-term outcomes research: development and description of exposures for 150 patients with acute lung injuryDale M Needham
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
J Crit Care 22:275-84. 2007..This report describes the development of a strategy for comprehensively measuring relevant exposures for long-term outcomes research, and presents empiric results from its implementation... - Hospital volume and mortality for mechanical ventilation of medical and surgical patients: a population-based analysis using administrative dataDale M Needham
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
Crit Care Med 34:2349-54. 2006..For medical patients, higher mortality may occur in a subgroup of low-volume hospitals that do not routinely transfer their patients to larger-volume facilities. This finding needs further investigation in a larger-sized study... 
Psychiatric morbidity in survivors of the acute respiratory distress syndrome: a systematic reviewDimitry S Davydow
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Psychosom Med 70:512-9. 2008....- A system factors analysis of airway events from the Intensive Care Unit Safety Reporting System (ICUSRS)Dale M Needham
Pulmonary and Critical Care Medicine, and Dana Center for Preventive Ophthalmology Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Crit Care Med 32:2227-33. 2004..Prevention efforts should focus on critically ill infants and patients with complex medical conditions. Managers should ensure appropriate ICU staffing to limit the impact of airway events when they occur... - Studying outcomes of intensive care unit survivors: the role of the cohort studyDavid W Dowdy
School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Intensive Care Med 31:914-21. 2005..CONCLUSIONS: We make recommendations for the design of future cohort studies to maximize the impact of this research in improving the long-term outcomes of critically ill patients... - Quality of life in adult survivors of critical illness: a systematic review of the literatureDavid W Dowdy
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Intensive Care Med 31:611-20. 2005..This systematic review provides a general understanding of QOL following critical illness and can serve as a standard of comparison for QOL studies in specific ICU subpopulations... - Mechanical ventilation in Ontario, 1992-2000: incidence, survival, and hospital bed utilization of noncardiac surgery adult patientsDale M Needham
Department of Critical Care Medicine and Medicine, University of Toronto, Toronto, Canada
Crit Care Med 32:1504-9. 2004..The increase, over time, in risk-adjusted mortality rate of mechanically ventilated patients is concerning and requires further investigation... - The efficacy of sirolimus- and paclitaxel-eluting stents: a meta-analysis of randomized controlled trialsMichelle M Kittleson
Department of Medicine, Division of Cardiology, Epidemiology and Clinical Research, John Hopkins Medical Institute, Baltimore, MD, USA
Can J Cardiol 21:581-7. 2005.... - Informed consent in the critically ill: a two-step approach incorporating delirium screeningEddy Fan
Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
Crit Care Med 36:94-9. 2008..We describe a two-step process for informed consent and evaluate the natural history of patients' competency by repeated application of this process during their hospitalization... - 24-hour intensivist staffing: balancing benefits and costsAdam Sapirstein
Crit Care Med 36:367-8. 2008 - Troponin I and T levels in renal failure patients without acute coronary syndrome: a systematic review of the literatureDale M Needham
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Can J Cardiol 20:1212-8. 2004..Among hemodialysis patients without ACS symptoms, a positive troponin T helps predict all-cause mortality... - Patient and intensive care unit organizational factors associated with low tidal volume ventilation in acute lung injuryNsikak J Umoh
Department of Surgery, Geisinger Medical Center, Danville, PA, USA
Crit Care Med 36:1463-8. 2008..Within the intensive care unit (ICU) setting, low tidal volume ventilation (LTVV) in patients with acute lung injury (ALI) significantly decreases mortality. However, LTVV has not achieved widespread adoption... - Mechanical ventilation and disuse atrophy of the diaphragmEddy Fan
N Engl J Med 359:90-1; author reply 91-2. 2008 - The science of quality improvementEddy Fan
JAMA 300:390-1; author reply 391-2. 2008 - Patient care seeking barriers and tuberculosis programme reform: a qualitative studyDale M Needham
PO Box 266, Ilderton, Ont, Canada NOM 2AO
Health Policy 67:93-106. 2004..The patient's perspective and related care seeking barriers should be considered in reviewing existing tuberculosis programmes and policy, evaluating potential programme reform and assessing new tuberculosis interventions... - Deciding who to admit to a critical care unitEddy Fan
BMJ 335:1103-4. 2007 - Barriers to low tidal volume ventilation in acute respiratory distress syndrome: survey development, validation, and resultsCheryl R Dennison
School of Nursing, Johns Hopkins University, Baltimore, MD, USA
Crit Care Med 35:2747-54. 2007..To evaluate perceived attitudes, knowledge, and behaviors regarding the use of low tidal volume ventilation in acute respiratory distress syndrome among physicians, nurses, and respiratory therapists in intensive care units... - The importance of understanding the costs of critical care and mechanical ventilationDale M Needham
Crit Care Med 33:1434-5. 2005 - Ventilatory management of acute lung injury and acute respiratory distress syndromeEddy Fan
Interdepartmental Division of Critical Care Medicine and Department of Medicine, University of Toronto and University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada
JAMA 294:2889-96. 2005..Further research is needed to identify barriers to widespread adoption of this strategy, as well as the role of alternative ventilation modes and adjunctive therapies... - Quality of life after acute respiratory distress syndrome: a meta-analysisDavid W Dowdy
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Intensive Care Med 32:1115-24. 2006..CONCLUSIONS: ARDS survivors in different clinical settings experience similar decrements in QOL. The precise magnitude of these decrements helps clarify the long-term prognosis for ARDS survivors... - Projected incidence of mechanical ventilation in Ontario to 2026: Preparing for the aging baby boomersDale M Needham
Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada
Crit Care Med 33:574-9. 2005..Existing evidence-based strategies that improve both the efficiency and efficacy of critical care services should be carefully evaluated for widespread implementation... - An intensivist all day, keeps the bad outcomes awayEddy Fan
Crit Care Med 35:286-7. 2007 - Critically appraise before you believe: the quality of meta-analyses in critical care medicineDale M Needham
Crit Care Med 35:666-7. 2007 - Systematic review identifies number of strategies important for retaining study participantsKaren A Robinson
Division of Internal Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
J Clin Epidemiol 60:757-65. 2007..We conducted a systematic review of studies with a primary focus on strategies to retain participants in health care research... - Neuromuscular dysfunction acquired in critical illness: a systematic reviewRobert D Stevens
Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 8 140, Baltimore, MD 21287, USA
Intensive Care Med 33:1876-91. 2007..To determine the prevalence, risk factors, and outcomes of critical illness neuromuscular abnormalities (CINMA)... - The role of future longitudinal studies in ICU survivors: understanding determinants and pathophysiology of weakness and neuromuscular dysfunctionCatherine L Hough
Department of Medicine, University of Washington, Seattle, Washington, USA
Curr Opin Crit Care 13:489-96. 2007..The goals of this review are to discuss the pathophysiology and determinants of muscle weakness and neuromuscular dysfunction after critical illness, and to offer thoughts regarding the role of future longitudinal studies in this area... - Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical functionDale M Needham
Division of Pulmonary and Critical Care Medicine, and Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland 21205, USA
JAMA 300:1685-90. 2008..Emerging research in this field provides preliminary evidence supporting the safety, feasibility, and potential benefits of early mobilization in critical care medicine...