C C Naus

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Altered gap junctional communication, intercellular signaling, and growth in cultured astrocytes deficient in connexin43
    C C Naus
    Department of Anatomy and Cell Biology, University of Western Ontario, London, Canada
    J Neurosci Res 49:528-40. 1997
  2. ncbi Characterization of CArG-binding protein A initially identified by differential display
    W J Rushlow
    Department of Anatomy and Cell Biology, The University of Western Ontario and The London Health Sciences Centre, Canada
    Neuroscience 94:637-49. 1999
  3. ncbi A neuroprotective role for gap junctions
    C C Naus
    Department of Anatomy and Cell Biology, The University of Western Ontario, London, Canada
    Cell Commun Adhes 8:325-8. 2001
  4. ncbi Connexin43 null mutation increases infarct size after stroke
    R Siushansian
    Department of Anatomy and Cell Biology, The University of Western Ontario, London, ON, Canada N6A 5C1
    J Comp Neurol 440:387-94. 2001
  5. ncbi Clinical and pathological observations in men lacking the gap junction protein connexin 32
    A F Hahn
    Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, Canada
    Muscle Nerve Suppl 9:S39-48. 2000
  6. ncbi Determination of a potential role of the CCN family of growth regulators in connexin43 transfected C6 glioma cells
    T L McLeod
    Department of Anatomy and Cell Biology, The University of Western Ontario, London, Canada
    Cell Commun Adhes 8:441-5. 2001
  7. ncbi Doubly mutant mice, deficient in connexin32 and -43, show normal prenatal development of organs where the two gap junction proteins are expressed in the same cells
    F D Houghton
    Department of Physiology, University of Western Ontario, London, Canada
    Dev Genet 24:5-12. 1999
  8. ncbi Changes in CArG-binding protein A expression levels following injection(s) of the D1-dopamine agonist SKF-82958 in the intact and 6-hydroxydopamine-lesioned rat
    W J Rushlow
    Department of Anatomy and Cell Biology, The University of Western Ontario, Ontario, London, Canada
    Neuroscience 98:69-78. 2000
  9. ncbi Array analysis of the genes regulated during neuronal differentiation of human embryonal cells
    M Bani-Yaghoub
    The John P Robarts Research Institute, London, ON, Canada
    Biochem Cell Biol 79:387-98. 2001
  10. ncbi Connexin43 suppresses MFG-E8 while inducing contact growth inhibition of glioma cells
    G S Goldberg
    Biological Sciences, State University of New York, Buffalo 14260, USA
    Cancer Res 60:6018-26. 2000

Collaborators

Detail Information

Publications14

  1. ncbi Altered gap junctional communication, intercellular signaling, and growth in cultured astrocytes deficient in connexin43
    C C Naus
    Department of Anatomy and Cell Biology, University of Western Ontario, London, Canada
    J Neurosci Res 49:528-40. 1997
    ..These results suggest that gap junctional intercellular communication mediated by Cx43 is not critical for astrocyte differentiation but is likely involved in the regulation of intercellular calcium signaling and cell growth...
  2. ncbi Characterization of CArG-binding protein A initially identified by differential display
    W J Rushlow
    Department of Anatomy and Cell Biology, The University of Western Ontario and The London Health Sciences Centre, Canada
    Neuroscience 94:637-49. 1999
    ..The results of the current study leads us to suggest that CArG-binding protein A may be involved in brain development and the regulation of the serum response element...
  3. ncbi A neuroprotective role for gap junctions
    C C Naus
    Department of Anatomy and Cell Biology, The University of Western Ontario, London, Canada
    Cell Commun Adhes 8:325-8. 2001
    ..These findings support the hypothesis that gap junctions play a neuroprotective role against glutamate cytotoxicity...
  4. ncbi Connexin43 null mutation increases infarct size after stroke
    R Siushansian
    Department of Anatomy and Cell Biology, The University of Western Ontario, London, ON, Canada N6A 5C1
    J Comp Neurol 440:387-94. 2001
    ..4 +/- 1.4 mm(3) vs. 7.7 +/- 0.82 mm(3), P < 0.002). These results suggest that augmentation of GJIC in astrocytes may contribute to neuroprotection after ischemic injury...
  5. ncbi Clinical and pathological observations in men lacking the gap junction protein connexin 32
    A F Hahn
    Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, Canada
    Muscle Nerve Suppl 9:S39-48. 2000
    ..The predicted absence of Cx 32 gap junctions is shown to be associated with a severe dysfunction of the axon-Schwann cell unit. Observed changes resemble those of Cx 32-null mice. No central nervous system changes were demonstrated...
  6. ncbi Determination of a potential role of the CCN family of growth regulators in connexin43 transfected C6 glioma cells
    T L McLeod
    Department of Anatomy and Cell Biology, The University of Western Ontario, London, Canada
    Cell Commun Adhes 8:441-5. 2001
    ..Furthermore, confocal microscopy indicates that NOV colocalizes with Cx43 plaques at the cell membrane. These findings provide insight into the possible role of Nov and Cyr61 in tumour cells...
  7. ncbi Doubly mutant mice, deficient in connexin32 and -43, show normal prenatal development of organs where the two gap junction proteins are expressed in the same cells
    F D Houghton
    Department of Physiology, University of Western Ontario, London, Canada
    Dev Genet 24:5-12. 1999
    ..Either gap junctional coupling is dispensable in embryonic and fetal cells in which these two connexins are coexpressed, or coupling is provided by yet another connexin when both are absent...
  8. ncbi Changes in CArG-binding protein A expression levels following injection(s) of the D1-dopamine agonist SKF-82958 in the intact and 6-hydroxydopamine-lesioned rat
    W J Rushlow
    Department of Anatomy and Cell Biology, The University of Western Ontario, Ontario, London, Canada
    Neuroscience 98:69-78. 2000
    ..The results demonstrate that CArG-binding protein A responds to SKF-82958 and that the changes in CArG-binding protein A match perfectly with the pattern of c-Fos induction induced by the D1 agonist...
  9. ncbi Array analysis of the genes regulated during neuronal differentiation of human embryonal cells
    M Bani-Yaghoub
    The John P Robarts Research Institute, London, ON, Canada
    Biochem Cell Biol 79:387-98. 2001
    ..This information can also be used in cell therapy and transplantation in which the graft microenvironment and interaction with the host tissue is crucial...
  10. ncbi Connexin43 suppresses MFG-E8 while inducing contact growth inhibition of glioma cells
    G S Goldberg
    Biological Sciences, State University of New York, Buffalo 14260, USA
    Cancer Res 60:6018-26. 2000
    ..Furthermore, the ability of a Cx to regulate cell growth may rely on its ability to mediate the intercellular transfer of endogenous metabolites but not artificial dyes...
  11. ncbi Development of astrocytes and neurons in cultured brain slices from mice lacking connexin43
    J L Perez Velazquez
    Department of Physiology, Toronto Western Hospital, University of Toronto, Ont, Canada
    Brain Res Dev Brain Res 97:293-6. 1996
    ..These results suggest that intercellular communication mediated through connexin43 is not essential for the development of astrocytes and neurons but may play a role in regulating astrocytic migration...
  12. pmc Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV)
    N Gupta
    Department of Surgery, University of Chicago, Chicago IL 60637, USA
    Mol Pathol 54:293-9. 2001
    ..The antiproliferative activity of CCN3 (NOV) established in this work sets the stage for the potential use of CCN proteins in molecular oncology...
  13. ncbi Upregulation of gap junction connexin 32 with epileptiform activity in the isolated mouse hippocampus
    J Li
    Bloorview Epilepsy Program, Toronto Western Research Institute, University Health Network, ON, Canada
    Neuroscience 105:589-98. 2001
    ....
  14. ncbi Connexin43 enhances glioma invasion by a mechanism involving the carboxy terminus
    Dave C Bates
    Department of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, British Columbia, Canada
    Glia 55:1554-64. 2007
    ..Furthermore, it is the first report to suggest that the Cx43 CT plays an important role in glioma motility...