R P Myers

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. ncbi request reprint Liver stiffness by transient elastography predicts liver-related complications and mortality in patients with chronic liver disease
    Jack X Q Pang
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 9:e95776. 2014
  2. pmc Clinical associations and potential novel antigenic targets of autoantibodies directed against rods and rings in chronic hepatitis C infection
    Laura M Stinton
    Liver Unit, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada
    BMC Gastroenterol 13:50. 2013
  3. pmc Postoperative complications following colectomy for ulcerative colitis: a validation study
    Christopher Ma
    Inflammatory Bowel Disease Clinic, University of Calgary, Calgary, Alberta, Canada
    BMC Gastroenterol 12:39. 2012
  4. doi request reprint B-cell depletion with rituximab in patients with primary biliary cirrhosis refractory to ursodeoxycholic acid
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Gastroenterol 108:933-41. 2013
  5. pmc Revision of MELD to include serum albumin improves prediction of mortality on the liver transplant waiting list
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 8:e51926. 2013
  6. ncbi request reprint Hospital performance reports based on severity adjusted mortality rates in patients with cirrhosis depend on the method of risk adjustment 
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Alberta, Canada
    Ann Hepatol 11:526-35. 2012
  7. doi request reprint Controlled Attenuation Parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Liver Int 32:902-10. 2012
  8. doi request reprint Discordance in fibrosis staging between liver biopsy and transient elastography using the FibroScan XL probe
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Hepatol 56:564-70. 2012
  9. pmc The burden of hepatitis C virus infection is growing: a Canadian population-based study of hospitalizations from 1994 to 2004
    Robert P Myers
    Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Canada
    Can J Gastroenterol 22:381-7. 2008
  10. doi request reprint Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Hepatology 55:199-208. 2012

Collaborators

Detail Information

Publications84

  1. ncbi request reprint Liver stiffness by transient elastography predicts liver-related complications and mortality in patients with chronic liver disease
    Jack X Q Pang
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 9:e95776. 2014
    ..Most hepatic complications occur in patients with advanced fibrosis. Our objective was to determine the ability of LSM by TE to predict hepatic complications and mortality in a large cohort of patients with chronic liver disease...
  2. pmc Clinical associations and potential novel antigenic targets of autoantibodies directed against rods and rings in chronic hepatitis C infection
    Laura M Stinton
    Liver Unit, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada
    BMC Gastroenterol 13:50. 2013
    ..Our objectives were to determine the prevalence and clinical associations of RR autoantibodies in HCV patients, and identify related novel autoantibody targets...
  3. pmc Postoperative complications following colectomy for ulcerative colitis: a validation study
    Christopher Ma
    Inflammatory Bowel Disease Clinic, University of Calgary, Calgary, Alberta, Canada
    BMC Gastroenterol 12:39. 2012
    ..This study compares risk estimates for predictors of postoperative complication derived from administrative data against that of chart review and evaluates the accuracy of administrative coding for this population...
  4. doi request reprint B-cell depletion with rituximab in patients with primary biliary cirrhosis refractory to ursodeoxycholic acid
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Gastroenterol 108:933-41. 2013
    ..The objective of this study was to assess the safety and efficacy of rituximab in patients with PBC refractory to UDCA...
  5. pmc Revision of MELD to include serum albumin improves prediction of mortality on the liver transplant waiting list
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 8:e51926. 2013
    ..Our objective was to assess revisions to MELD and MELDNa that include serum albumin for predicting waiting list mortality...
  6. ncbi request reprint Hospital performance reports based on severity adjusted mortality rates in patients with cirrhosis depend on the method of risk adjustment 
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Alberta, Canada
    Ann Hepatol 11:526-35. 2012
    ..We aimed to determine the impact of the choice of risk adjustment method on hospital rankings based on mortality rates in cirrhotic patients...
  7. doi request reprint Controlled Attenuation Parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Liver Int 32:902-10. 2012
    ..Accurate tools for the noninvasive detection of hepatic steatosis are needed. The Controlled Attenuation Parameter (CAP) specifically targets liver steatosis using a process based on transient elastography...
  8. doi request reprint Discordance in fibrosis staging between liver biopsy and transient elastography using the FibroScan XL probe
    Robert P Myers
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Hepatol 56:564-70. 2012
    ..Our objectives were to examine the prevalence, risk factors, and causes of discordance between fibrosis estimated by the FibroScan XL probe and biopsy...
  9. pmc The burden of hepatitis C virus infection is growing: a Canadian population-based study of hospitalizations from 1994 to 2004
    Robert P Myers
    Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Canada
    Can J Gastroenterol 22:381-7. 2008
    ..Simulation analyses have suggested that HCV will place an increasing burden on the health care system as the infected population ages, but supportive clinical data are limited...
  10. doi request reprint Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Hepatology 55:199-208. 2012
    ..8 versus 7.8 kPa; P < 0.00005). The AUROC of the XL and M probes were similar for ≥ F2 fibrosis (0.83 versus 0.86; P = 0.19) and cirrhosis (0.94 versus 0.91; P = 0.28)...
  11. pmc The effect of weekend versus weekday admission on outcomes of esophageal variceal hemorrhage
    R P Myers
    University of Calgary, Calgary, Alberta, Canada
    Can J Gastroenterol 23:495-501. 2009
    ..Because esophageal variceal hemorrhage (EVH) requires complex management and urgent endoscopic intervention, limitations in physician expertise and the availability of endoscopy on weekends may be associated with increased EVH mortality...
  12. pmc Transient elastography for the noninvasive assessment of liver fibrosis: a multicentre Canadian study
    Robert P Myers
    Division of Gastroenterology, Department of Medicine, University of Calgary, Alberta
    Can J Gastroenterol 24:661-70. 2010
    ..Liver stiffness measurement (LSM) using transient elastography (TE) is a promising tool for the noninvasive assessment of hepatic fibrosis...
  13. doi request reprint Impact of liver disease, alcohol abuse, and unintentional ingestions on the outcomes of acetaminophen overdose
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 6:918-25; quiz 837. 2008
    ..In this population-based study, we examined outcomes of acetaminophen overdose, with particular attention to these risk factors...
  14. ncbi request reprint Noninvasive diagnosis of nonalcoholic fatty liver disease
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Ann Hepatol 8:S25-33. 2009
    ..Until such tools are developed, liver biopsy remains an important tool in the assessment of patients with NAFLD...
  15. doi request reprint Gender, renal function, and outcomes on the liver transplant waiting list: assessment of revised MELD including estimated glomerular filtration rate
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Hepatol 54:462-70. 2011
    ..Our objectives were to investigate gender disparities in outcomes among LT candidates and to assess a revised MELD, including estimated glomerular filtration rate (eGFR), for predicting waiting list mortality...
  16. pmc Impact of pharmaceutical industry versus university sponsorship on survey response: a randomized trial among Canadian hepatitis C care providers
    Robert P Myers
    University of Calgary, Calgary, Canada
    Can J Gastroenterol 21:169-75. 2007
    ....
  17. pmc Association between leptin, metabolic factors and liver histology in patients with chronic hepatitis C
    Robert P Myers
    Department of Medicine, University of Calgary, Calgary, Canada
    Can J Gastroenterol 21:289-94. 2007
    ..The objective of the present study was to determine the clinical and histological correlates of serum leptin in HCV-infected patients, and to determine its utility in predicting liver histological lesions...
  18. pmc Hospitalizations for acetaminophen overdose: a Canadian population-based study from 1995 to 2004
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Public Health 7:143. 2007
    ..Acetaminophen overdose (AO) is the most common cause of acute liver failure. We examined temporal trends and sociodemographic risk factors for AO in a large Canadian health region...
  19. ncbi request reprint Emergency department visits for acetaminophen overdose: a Canadian population-based epidemiologic study (1997-2002)
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Alberta
    CJEM 9:267-74. 2007
    ..We describe the epidemiology of emergency department (ED) visits for acetaminophen overdose in a large Canadian health region, with a focus on sociodemographic risk factors and temporal trends...
  20. doi request reprint Prevalence, risk factors and causes of discordance in fibrosis staging by transient elastography and liver biopsy
    Robert P Myers
    Liver Unit, Department of Medicine, Division of Gastroenterology, University of Calgary, Calgary, AB, Canada
    Liver Int 30:1471-80. 2010
    ..Our objectives were to examine the prevalence, risk factors and causes of discordance between fibrosis estimated by TE and liver biopsy...
  21. ncbi request reprint Characteristics of patients with cirrhosis who are discharged from the hospital against medical advice
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 7:786-92. 2009
    ..Patients discharged from hospital against medical advice are at risk of adverse health outcomes. The frequency and predictors of self-discharge in cirrhotic patients have not been examined...
  22. doi request reprint Relationship between hospital volume and outcomes of esophageal variceal bleeding in the United States
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 6:789-98. 2008
    ..The objective of this study was to assess the volume-outcome relationship in patients with esophageal variceal bleeding...
  23. pmc Validation of coding algorithms for the identification of patients with primary biliary cirrhosis using administrative data
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, 3280 Hospital Drive Northwest, Calgary, Alberta
    Can J Gastroenterol 24:175-82. 2010
    ..Large-scale epidemiological studies of primary biliary cirrhosis (PBC) have been hindered by difficulties in case ascertainment...
  24. doi request reprint Epidemiology and natural history of primary biliary cirrhosis in a Canadian health region: a population-based study
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Hepatology 50:1884-92. 2009
    ..87; 95% CI 1.89-4.17); male sex (hazard ratio [HR] 3.80; 95% CI 1.85-7.82) and an older age at diagnosis (HR per additional year, 1.06; 95% CI 1.03-1.10) were independent predictors of mortality...
  25. doi request reprint Utilization rates, complications and costs of percutaneous liver biopsy: a population-based study including 4275 biopsies
    Robert P Myers
    Department of Medicine, Division of Gastroenterology, Liver Unit, University of Calgary, Calgary, AB, Canada
    Liver Int 28:705-12. 2008
    ..Because biopsy practices may be changing, we studied patterns of use in a large Canadian Health Region. We aimed to describe trends in biopsy utilization and the incidence and costs of complications from a population-based perspective...
  26. pmc Validation of ICD-9-CM/ICD-10 coding algorithms for the identification of patients with acetaminophen overdose and hepatotoxicity using administrative data
    Robert P Myers
    Liver Unit, Division of Gastroenterology, Department of Medicine University of Calgary, Calgary, Alberta, Canada
    BMC Health Serv Res 7:159. 2007
    ..Acetaminophen overdose is the most common cause of acute liver failure (ALF). Our objective was to develop coding algorithms using administrative data for identifying patients with acetaminophen overdose and hepatic complications...
  27. pmc Outcomes of chronic hepatitis C therapy in patients treated in community versus academic centres in Canada: final results of APPROACH (a prospective study of peginterferon alfa-2a and ribavirin at academic and community centres in Canada)
    Robert P Myers
    University of Calgary, Alberta
    Can J Gastroenterol 25:503-10. 2011
    ..In patients chronically infected with the hepatitis C virus (HCV), it is not established whether viral outcomes or health-related quality of life (HRQoL) differ between individuals treated at academic or community centres...
  28. ncbi request reprint Pegylated interferon alpha 2b and ribavirin in HIV/hepatitis C virus-co-infected non-responders and relapsers to IFN-based therapy
    Robert P Myers
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    AIDS 18:75-9. 2004
    ..Pegylated interferon alpha (PEG-IFN-alpha) and ribavirin is the most effective available treatment for chronic hepatitis C virus (HCV) infection. Its role in HIV/HCV-co-infected patients who have failed IFN-based therapy is unclear...
  29. ncbi request reprint Reinforced interferon alpha-2b and ribavirin is more effective than standard combination therapy in the retreatment of chronic hepatitis C previously nonresponsive to interferon: a randomized trial
    T Poynard
    Service d Hepatogastroenterologie, Groupe Hospitalier Pitie Salpetriere, Universite Paris 6, 47 83 boulevard de l Hopital, CNRS ESA 8067, 75651 Paris Cedex 13, France
    J Viral Hepat 10:197-204. 2003
    ..30 and 0.20, respectively). Hence in nonresponders, a high-dose 48-week regimen of IFN and ribavirin combination was more effective than a regimen with interferon at lower dose and ribavirin for 24 weeks only...
  30. ncbi request reprint The impact of prior hepatitis B virus infection on liver histology and the response to interferon therapy in chronic hepatitis C
    R P Myers
    Department of Hepatology and Gastroenterology, Groupe Hospitalier Pitie Salpetriere, Paris, France
    J Viral Hepat 10:103-10. 2003
    ..36; 95% confidence interval, 0.45 to 4.06; P = 0.58). In conclusion, previous HBV infection does not affect liver histology or the response to IFN-based therapy in patients with chronic hepatitis C...
  31. ncbi request reprint The rate of fibrosis progression is an independent predictor of the response to antiviral therapy in chronic hepatitis C
    R P Myers
    Division of Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    J Viral Hepat 10:16-22. 2003
    ..92; P=0.01). Hence the rate of fibrosis progression is an independent predictor of SVR to IFN-based therapy in patients with chronic hepatitis C. This additional factor should be considered in economic models evaluating this condition...
  32. pmc Management of chronic hepatitis C in French departments of internal medicine and infectious diseases
    P Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651, Paris, France
    Epidemiol Infect 133:305-14. 2005
    ..Nevertheless, means of increasing the availability of antiviral therapies, particularly for patients with HIV co-infection or injecting drug use, require further study...
  33. doi request reprint Randomised clinical trial: the efficacy of treatment, guided by a shorter duration of response, using peginterferon alfa-2a plus ribavirin for hepatitis C virus other than genotypes 2 or 3
    S S Lee
    University of Calgary Liver Unit, Calgary, Alberta, Canada
    Aliment Pharmacol Ther 35:37-47. 2012
    ..The efficacy of individualised antiviral treatment durations for chronic hepatitis C remains unclear...
  34. ncbi request reprint Historical features are poor predictors of liver fibrosis in Canadian patients with chronic hepatitis C
    R P Myers
    Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Viral Hepat 8:249-55. 2001
    ..Alternate noninvasive methods of predicting hepatic fibrosis are needed...
  35. doi request reprint Predicting in-hospital mortality in patients with cirrhosis: results differ across risk adjustment methods
    Robert P Myers
    Department of Medicine, Division of Gastroenterology, University of Calgary, Calgary, Alberta, Canada
    Hepatology 49:568-77. 2009
    ..Because different methods often produce divergent severity rankings, analyses of provider-specific outcomes may be biased depending on the method used...
  36. ncbi request reprint Serum biochemical markers accurately predict liver fibrosis in HIV and hepatitis C virus co-infected patients
    Robert P Myers
    Department of Hepatology and Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    AIDS 17:721-5. 2003
    ..Our aim was to determine the operating characteristics of a non-invasive index of biochemical markers for the prediction of fibrosis in patients with HIV/HCV co-infection...
  37. doi request reprint Virology and clinical sequelae of long-term antiviral therapy in a North American cohort of hepatitis B virus (HBV)/human immunodeficiency virus type 1 (HIV-1) co-infected patients
    C S Coffin
    Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, 3280 Hospital Drive NW, University of Calgary, Calgary, AB T2N 4Z6, Canada
    J Clin Virol 57:103-8. 2013
    ..There are limited recent data worldwide on clinical and virological outcomes in hepatitis B virus (HBV) and human immunodeficiency virus (HIV) coinfected patients on dual active antiretroviral therapy (ART)...
  38. ncbi request reprint Fatigue in patients with chronic hepatitis C
    T Poynard
    Departments of Hepatogastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    J Viral Hepat 9:295-303. 2002
    ..Hence, fatigue is the most frequent extrahepatic manifestation in patients infected with HCV. Fatigue is independently associated with female gender, age over 50 years, cirrhosis, depression and purpura...
  39. pmc Ischemic colitis during pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
    Yvette Leung
    Department of Medicine, University of Calgary, Alberta
    Can J Gastroenterol 20:661-3. 2006
    ..Physicians should be aware of this complication, and should consider it in any HCV-infected patient taking pegylated IFN-alpha and ribavirin who develops abdominal discomfort and gastrointestinal bleeding...
  40. ncbi request reprint Interferon-alpha and ribavirin treatment in patients with hepatitis C virus-related systemic vasculitis
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    Arthritis Rheum 46:3317-26. 2002
    ..Therefore, we retrospectively analyzed the response to treatment in patients with chronic hepatitis C complicated by systemic vasculitis who had received antiviral therapy with interferon-alpha (IFNalpha) and ribavirin...
  41. ncbi request reprint Fatal hepatic decompensation in a patient with hepatitis B cirrhosis following famciclovir withdrawal
    R P Myers
    Division of Gastroenterology and Hepatology, University of Calgary, Alberta
    Can J Gastroenterol 14:725-7. 2000
    ..Until further data are available regarding the safety of withdrawal of these agents, indefinite treatment may be required in patients with established cirrhosis...
  42. ncbi request reprint Reactivation of hepatitis B e antigen-negative chronic hepatitis B in a bone marrow transplant recipient following lamivudine withdrawal
    R P Myers
    Department of Pathology, University of Calgary Medical Clinical, Calgary, Alberta, Canada
    Can J Gastroenterol 15:599-603. 2001
    ..Clinicians should consider the risk of inducing serious flares of hepatic inflammation due to abrupt nucleoside analogue withdrawal in these patients...
  43. doi request reprint Morbidity and mortality following colorectal surgery in patients with end-stage renal failure: a population-based study
    Sebastien Drolet
    Department of Surgery, University of Calgary, Calgary, Alberta, Canada
    Dis Colon Rectum 53:1508-16. 2010
    ..The risk of abdominal surgery in patients with end-stage renal failure is poorly defined. Our objective was to describe outcomes of colorectal surgery in dialysis patients from a population-based perspective...
  44. doi request reprint Inflammatory bowel disease patients who leave hospital against medical advice: predictors and temporal trends
    Gilaad G Kaplan
    Inflammatory Bowel Disease Clinic, University of Calgary, Calgary, Alberta, Canada
    Inflamm Bowel Dis 15:845-51. 2009
    ..Thus, we determined the prevalence of self-discharge, assessed predictors of AMA status, and evaluated time trends...
  45. ncbi request reprint Multiple focal nodular hyperplasia and steatosis: Atypical imaging characteristics
    R P Myers
    Department of Medicine, Liver Disease Unit, London Health Sciences Centre, University of Western Ontario, London, Ontario N6A 5A5, Canada
    Can J Gastroenterol 15:137-42. 2001
    ..The investigation of a patient with a malignancy and expanding hepatic lesions is challenging. This case illustrates the usefulness of the (99m)technetium-labelled sulphur colloid scan in the evaluation of patients with hepatic lesions...
  46. ncbi request reprint Progression of liver fibrosis in women infected with hepatitis C: long-term benefit of estrogen exposure
    Vincent Di Martino
    Service d Hepato Gastroenterologie, GH Pitié Salpétrière, Paris, France
    Hepatology 40:1426-33. 2004
    ..Pregnancies may have a beneficial impact on the long-term progression of liver fibrosis...
  47. ncbi request reprint Biochemical markers of liver fibrosis: a comparison with historical features in patients with chronic hepatitis C
    Robert P Myers
    Department of Hepato Gastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    Am J Gastroenterol 97:2419-25. 2002
    ..The aims of this study were: 1) to compare an index of five biochemical markers with historical features; and 2) to determine the utility of combining these features with the five-marker index for the prediction of significant fibrosis...
  48. ncbi request reprint FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy
    Abdel Aziz M Shaheen
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Gastroenterol 102:2589-600. 2007
    ..Our objective was to systematically review studies describing the accuracy of these tests for predicting HCV-related fibrosis...
  49. ncbi request reprint A comparison of fibrosis progression in chronic liver diseases
    Thierry Poynard
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, et UPRESA 8067 CNRS, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France
    J Hepatol 38:257-65. 2003
    ..No study has compared the liver fibrosis progression rates among chronic liver diseases and the risk factors in order to better organize screening strategies...
  50. ncbi request reprint Biochemical markers of fibrosis in patients with chronic hepatitis C: a comparison with prothrombin time, platelet count, and age-platelet index
    Robert P Myers
    Department of Gastroenterology and Hepatology, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Dig Dis Sci 48:146-53. 2003
    ..In conclusion, an index of five biochemical markers accurately predicts significant hepatitis C-related fibrosis and is superior to traditional markers...
  51. doi request reprint Morbidity and mortality following coronary artery bypass graft surgery in patients with cirrhosis: a population-based study
    Abdel Aziz M Shaheen
    Liver Unit, Department of Medicine, Division of Gastroenterology, University of Calgary, Calgary, AB, Canada
    Liver Int 29:1141-51. 2009
    ..The risk of cardiac surgery in patients with cirrhosis is poorly defined. Our objective was to describe outcomes of coronary artery bypass graft (CABG) surgery in cirrhotic patients from a population-based perspective...
  52. ncbi request reprint Weekend versus weekday admission and mortality from gastrointestinal hemorrhage caused by peptic ulcer disease
    Abdel Aziz M Shaheen
    Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 7:303-10. 2009
    ..Management of upper gastrointestinal bleeding (UGIB) often requires urgent endoscopic intervention; limitations in its availability on weekends might be associated with increased mortality, compared with patients admitted on weekdays...
  53. ncbi request reprint Silymarin treatment of viral hepatitis: a systematic review
    K E Mayer
    Liver Unit, Department of Medicine, University of Calgary, Calgary, Canada
    J Viral Hepat 12:559-67. 2005
    ..Nevertheless it may be worthwhile to determine its effects in conjunction with standard antiviral treatment...
  54. doi request reprint Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection
    Abdel Aziz M Shaheen
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    HIV Clin Trials 9:43-51. 2008
    ..Our objective was to systematically review studies describing the accuracy of serum marker panels for predicting fibrosis in HIV/HCV-coinfected patients...
  55. doi request reprint Epidemiology of gallstones
    Laura M Stinton
    Division of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    Gastroenterol Clin North Am 39:157-69, vii. 2010
    ..Others are modifiable: obesity, the metabolic syndrome, rapid weight loss, certain diseases (cirrhosis and Crohn disease), gallbladder stasis (from spinal cord injury or drugs, such as somatostatin), and lifestyle...
  56. ncbi request reprint Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis C-related fibrosis: a systematic review
    Abdel Aziz M Shaheen
    Liver Unit, Division of Gastroenterology, Department of Medicine University of Calgary, Calgary, Alberta, Canada
    Hepatology 46:912-21. 2007
    ..Future studies of novel markers should demonstrate improved accuracy and cost-effectiveness compared with this economical and widely available index...
  57. ncbi request reprint Prediction of liver histological lesions with biochemical markers in patients with chronic hepatitis B
    Robert P Myers
    Department of Hepatology and Gastroenterology, Groupe Hospitalier Pitie Salpetriere, Paris, France
    J Hepatol 39:222-30. 2003
    ..Liver biopsy is the gold standard for assessing hepatitis B virus (HBV)-related histology. The aim was to determine the diagnostic utility of noninvasive serum markers in patients with chronic hepatitis B...
  58. pmc Autoantibodies to GW bodies and other autoantigens in primary biliary cirrhosis
    L M Stinton
    Department of Medicine, University of Calgary, AB, Canada
    Clin Exp Immunol 163:147-56. 2011
    ..None of the autoantibodies were associated with differences in Mayo risk score or liver decompensation. This study is the first study to show that antibodies to RAP55, GW182 and GRASP-1 are the most common GWB targets in PBC...
  59. ncbi request reprint Acute interstitial nephritis due to omeprazole
    R P Myers
    Department of Medicine, University of Western Ontario, London, Canada
    Am J Gastroenterol 96:3428-31. 2001
    ..Management consisted of withdrawal of omeprazole and corticosteroid therapy in some patients. All but one patient recovered normal renal function. Corticosteroid therapy was well tolerated and may have been beneficial...
  60. doi request reprint The outcomes of pregnancy in patients with cirrhosis: a population-based study
    Abdel Aziz M Shaheen
    Liver Unit, Department of Medicine, Division of Gastroenterology, University of Calgary, Calgary, AB, Canada
    Liver Int 30:275-83. 2010
    ..The outcomes of pregnancy in patients with cirrhosis are poorly described. Our objective was to assess obstetric outcomes in cirrhotic women and their infants from a population-based perspective...
  61. doi request reprint A population-based study of pyogenic liver abscesses in the United States: incidence, mortality, and temporal trends
    Liisa Meddings
    Department of Medicine, University of Calgary, Alberta, Canada
    Am J Gastroenterol 105:117-24. 2010
    ..Few population-based studies have evaluated pyogenic liver abscess (PLA) in North America. We assessed the incidence of PLA and evaluated predictors of mortality...
  62. doi request reprint Pregnancy outcomes among liver transplant recipients in the United States: a nationwide case-control analysis
    Carla S Coffin
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Liver Transpl 16:56-63. 2010
    ..Additional studies evaluating mechanisms aimed at reducing these complications are necessary...
  63. ncbi request reprint Cardiac hepatopathy: clinical, hemodynamic, and histologic characteristics and correlations
    Robert P Myers
    Liver Unit, University of Calgary, Alberta, Canada
    Hepatology 37:393-400. 2003
    ..Hepatic fibrosis is common, but does not correlate with systemic or hepatic hemodynamics...
  64. ncbi request reprint Population-based analysis of practices and costs of surveillance for colonic dysplasia in patients with primary sclerosing cholangitis and colitis
    Gilaad G Kaplan
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Inflamm Bowel Dis 13:1401-7. 2007
    ..The aims of the present study were (1) to determine the incidence of dysplasia or CRC, (2) to assess surveillance practices, and (3) to assess the costs associated with surveillance of PSC patients...
  65. pmc A case of valproate-induced hyperammonemic encephalopathy: look beyond the liver
    Saleh Alqahtani
    Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alta
    CMAJ 177:568-9. 2007
  66. pmc Rofecoxib-induced hepatotoxicity: a forgotten complication of the coxibs
    Brian Yan
    Department of Medicine, University of Calgary, Alberta
    Can J Gastroenterol 20:351-5. 2006
    ..With new coxibs and expanding indications on the horizon, physicians in all areas of practice must be aware of this disorder and consider it in any patient who develops hepatic dysfunction after taking a coxib...
  67. ncbi request reprint Gallbladder polyps: epidemiology, natural history and management
    Robert P Myers
    Division of Gastroenterology, University of Calgary, Calgary, Canada
    Can J Gastroenterol 16:187-94. 2002
    ..Novel imaging techniques, including endoscopic ultrasonography and enhanced computed tomography, may aid in the differential diagnosis of these lesions and permit expectant management...
  68. ncbi request reprint Neurolytic celiac plexus block for pain control in unresectable pancreatic cancer
    Brian M Yan
    Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Gastroenterol 102:430-8. 2007
    ....
  69. ncbi request reprint [What are the indications for treatment of acute hepatitis C?]
    Robert P Myers
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, Paris
    Gastroenterol Clin Biol 26:B188-93. 2002
  70. ncbi request reprint Impact of treatment on extra hepatic manifestations in patients with chronic hepatitis C
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Paris Cedex 13, France
    J Hepatol 36:812-8. 2002
    ..The aim was to assess the prevalence of these symptoms prior to any treatment, and on prolonged follow-up in treated and untreated patients...
  71. ncbi request reprint Noninvasive prediction of fibrosis in patients with chronic hepatitis C
    Dominique Thabut
    Hepatology 37:1220-1; author reply 1221. 2003
  72. ncbi request reprint Mortality due to hepatitis C-related liver disease in HIV-infected patients in France (Mortavic 2001 study)
    Eric Rosenthal
    Service d Hematologie Clinique, Hopital Archet, Nice, France
    AIDS 17:1803-9. 2003
    ....
  73. ncbi request reprint The management of chronic viral hepatitis: a Canadian consensus conference 2004
    Morris Sherman
    University of Toronto, Toronto, Ontario, Canada
    Can J Gastroenterol 18:715-28. 2004
    ..The present document is meant to be used by practitioners and other health care providers, including public health staff and others not directly involved in patient care...
  74. doi request reprint After radical retropubic prostatectomy 'insignificant' prostate cancer has a risk of progression similar to low-risk 'significant' cancer
    Shomik Sengupta
    Department of Urology, Mayo Clinic, Rochester, MN 55905, USA
    BJU Int 101:170-4. 2008
    ....
  75. ncbi request reprint Subjective and objective comparison of critical care pathways for open donor nephrectomy
    Melinda K Knight
    Department of Urology, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55901, USA
    J Urol 167:2368-71. 2002
    ..We compared results of standard and fast-track care pathways after donor nephrectomy...
  76. ncbi request reprint Racial disparities in the management of hospitalized patients with cirrhosis and portal hypertension
    Robert P Myers
    Hepatology 47:358-60; author reply 360. 2008
  77. ncbi request reprint NNRTI-related or -unrelated hepatotoxicity?
    Pascal Lebray
    Hepatology 36:512-3; author reply 513-4. 2002
  78. ncbi request reprint Thrombolytic therapy of pulmonary embolism: a meta-analysis
    Gabriel Thabut
    Service de Pneumologie et Reanimation Respiratoire, Hopital Beaujon, 100 Avenue du Général Leclerc, 92110 Clichy, France
    J Am Coll Cardiol 40:1660-7. 2002
    ..We sought to assess the efficacy and safety of thrombolytic therapy in patients with an acute pulmonary embolism (PE)...
  79. doi request reprint Early continence outcomes of posterior musculofascial plate reconstruction during robotic and laparoscopic prostatectomy
    Mike M Nguyen
    Section of Laparoscopic and Robotic Surgery, Glickman Urological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    BJU Int 101:1135-9. 2008
    ....
  80. ncbi request reprint Conventional assessment of needle biopsy specimens is more useful than digital image analysis of proliferation and DNA ploidy in prediction of positive surgical margins at radical prostatectomy
    Shomik Sengupta
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 68:94-8. 2006
    ..The aim of this study was to assess the additional value of digital image analysis (DIA) of ploidy and proliferation on needle biopsies, in addition to the known preoperative predictors of +SMs at RRP...
  81. ncbi request reprint Increasing prostate specific antigen following radical prostatectomy and adjuvant hormonal therapy: doubling time predicts survival
    Shomik Sengupta
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 175:1684-90; discussion 1690. 2006
    ..We assessed the natural history of detectable PSA in such patients with particular emphasis on the prognostic usefulness of PSADT...
  82. ncbi request reprint The impact of surgical approach (nerve bundle preservation versus wide local excision) on surgical margins and biochemical recurrence following radical prostatectomy
    John F Ward
    Division of Urology, Department of Surgery, Naval Medical Center, Portsmouth, Virginia, USA
    J Urol 172:1328-32. 2004
    ..We examined whether neurovascular bundle preservation during RP is a risk factor for positive SMs and progression-free survival after adjusting for disease severity...
  83. ncbi request reprint Preoperative prostate specific antigen doubling time and velocity are strong and independent predictors of outcomes following radical prostatectomy
    Shomik Sengupta
    Department of Urology and Division of Biostatistics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Urol 174:2191-6. 2005
    ..We assessed preoperative PSA doubling time (PSADT) and PSA velocity (PSAV) as predictors of outcome following radical retropubic prostatectomy (RRP)...
  84. ncbi request reprint Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial
    Henry L Y Chan
    The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Ann Intern Med 147:745-54. 2007
    ..The efficacy of nucleoside and nucleotide analogues for hepatitis B has been linked to the magnitude and durability of hepatitis B virus (HBV) suppression...