Richelle Mychasiuk

Summary

Affiliation: University of Lethbridge
Country: Canada

Publications

  1. doi request reprint Prenatal bystander stress induces neuroanatomical changes in the prefrontal cortex and hippocampus of developing rat offspring
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Canada
    Brain Res 1412:55-62. 2011
  2. doi request reprint Persistent gene expression changes in NAc, mPFC, and OFC associated with previous nicotine or amphetamine exposure
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Canada Electronic address
    Behav Brain Res 256:655-61. 2013
  3. doi request reprint Does prenatal nicotine exposure alter the brain's response to nicotine in adolescence? A neuroanatomical analysis
    R Mychasiuk
    Canadian Centre for Behavioural Neurosciences, University of Lethbridge, Lethbridge, AB, Canada, T1K 3M4
    Eur J Neurosci 38:2491-503. 2013
  4. doi request reprint Paternal stress prior to conception alters DNA methylation and behaviour of developing rat offspring
    R Mychasiuk
    University of Lethbridge, Lethbridge, AB, Canada
    Neuroscience 241:100-5. 2013
  5. doi request reprint Long-term alterations to dendritic morphology and spine density associated with prenatal exposure to nicotine
    R Mychasiuk
    Canadian Centre for Behavioral Neuroscience, University of Lethbridge, Canada
    Brain Res 1499:53-60. 2013
  6. ncbi request reprint Effects of rat prenatal exposure to valproic acid on behaviour and neuro-anatomy
    R Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Alta, Canada
    Dev Neurosci 34:268-76. 2012
  7. doi request reprint Parental enrichment and offspring development: modifications to brain, behavior and the epigenome
    Richelle Mychasiuk
    University of Lethbridge, Canadian Centre for Behavioural Neuroscience, Canada
    Behav Brain Res 228:294-8. 2012
  8. doi request reprint Prenatal stress alters dendritic morphology and synaptic connectivity in the prefrontal cortex and hippocampus of developing offspring
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada
    Synapse 66:308-14. 2012
  9. doi request reprint Prenatal bystander stress alters brain, behavior, and the epigenome of developing rat offspring
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neurosciences, University of Lethbridge, Lethbridge, Alta, Canada
    Dev Neurosci 33:159-69. 2011
  10. doi request reprint Intensity matters: brain, behaviour and the epigenome of prenatally stressed rats
    R Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Alberta T1K3M4, Canada
    Neuroscience 180:105-10. 2011

Detail Information

Publications15

  1. doi request reprint Prenatal bystander stress induces neuroanatomical changes in the prefrontal cortex and hippocampus of developing rat offspring
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Canada
    Brain Res 1412:55-62. 2011
    ..Neuroanatomical changes of this extent occurring at such a critical time period will likely impact healthy maturation of the brain and long-term development...
  2. doi request reprint Persistent gene expression changes in NAc, mPFC, and OFC associated with previous nicotine or amphetamine exposure
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Canada Electronic address
    Behav Brain Res 256:655-61. 2013
    ..The changes in DNA methylation are consistent with the gene expression results and provide further support to the notion that DNA methylation is the key regulatory mechanism for experience dependent changes. ..
  3. doi request reprint Does prenatal nicotine exposure alter the brain's response to nicotine in adolescence? A neuroanatomical analysis
    R Mychasiuk
    Canadian Centre for Behavioural Neurosciences, University of Lethbridge, Lethbridge, AB, Canada, T1K 3M4
    Eur J Neurosci 38:2491-503. 2013
    ..Females showed additive effects in Par1, Cg3 and NAc whereas males demonstrated additive effects only in AID. Thus, the timing of nicotine exposure produced differential effects on cerebral organisation in a regionally specific manner...
  4. doi request reprint Paternal stress prior to conception alters DNA methylation and behaviour of developing rat offspring
    R Mychasiuk
    University of Lethbridge, Lethbridge, AB, Canada
    Neuroscience 241:100-5. 2013
    ..Development takes place in the centre of a complex interaction between maternal, paternal, and environmental influences, which combine to produce the various phenotypes and individual differences that we perceive...
  5. doi request reprint Long-term alterations to dendritic morphology and spine density associated with prenatal exposure to nicotine
    R Mychasiuk
    Canadian Centre for Behavioral Neuroscience, University of Lethbridge, Canada
    Brain Res 1499:53-60. 2013
    ..As changes were identified at P100, prenatal exposure to nicotine dramatically reorganized neuroanatomy in a persistent manner, likely altering the brain's response to normal and abnormal experiences...
  6. ncbi request reprint Effects of rat prenatal exposure to valproic acid on behaviour and neuro-anatomy
    R Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Alta, Canada
    Dev Neurosci 34:268-76. 2012
    ..Behavioural and anatomical findings from this study produced reliable results indicating that prenatal VPA exposure may be a viable model for the study of autism in rats...
  7. doi request reprint Parental enrichment and offspring development: modifications to brain, behavior and the epigenome
    Richelle Mychasiuk
    University of Lethbridge, Canadian Centre for Behavioural Neuroscience, Canada
    Behav Brain Res 228:294-8. 2012
    ..This study demonstrates that positive prenatal experiences; preconceptionally in fathers and prenatally in mothers, have the ability to significantly alter offspring developmental trajectories...
  8. doi request reprint Prenatal stress alters dendritic morphology and synaptic connectivity in the prefrontal cortex and hippocampus of developing offspring
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada
    Synapse 66:308-14. 2012
    ....
  9. doi request reprint Prenatal bystander stress alters brain, behavior, and the epigenome of developing rat offspring
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neurosciences, University of Lethbridge, Lethbridge, Alta, Canada
    Dev Neurosci 33:159-69. 2011
    ..Furthermore, this type of 'indirect' prenatal stress alters offspring DNA methylation patterns, gene expression profiles, and behavior...
  10. doi request reprint Intensity matters: brain, behaviour and the epigenome of prenatally stressed rats
    R Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Alberta T1K3M4, Canada
    Neuroscience 180:105-10. 2011
    ..The data from this study provide evidence to support a dose-dependent effect of prenatal stress on multiple aspects of brain development, potentially contributing to long-term outcomes...
  11. doi request reprint Prenatal nicotine exposure alters neuroanatomical organization of the developing brain
    Arif Muhammad
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada T1K 3M4
    Synapse 66:950-4. 2012
    ..These early changes in anatomy and behavior have important implications for later plasticity and long-term well-being...
  12. pmc Experience and the developing prefrontal cortex
    Bryan Kolb
    Department of Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, AB, Canada
    Proc Natl Acad Sci U S A 109:17186-93. 2012
    ..We begin with an overview of prefrontal functioning and development, and we conclude with a consideration of how early experiences influence prefrontal development and behavior...
  13. doi request reprint Prenatal stress produces sexually dimorphic and regionally specific changes in gene expression in hippocampus and frontal cortex of developing rat offspring
    Richelle Mychasiuk
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Alta, Canada
    Dev Neurosci 33:531-8. 2011
    ..These findings have important implications for generalized intervention strategies using a single methodology for all individuals...
  14. doi request reprint Brain plasticity in the developing brain
    Bryan Kolb
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, AB, Canada Electronic address
    Prog Brain Res 207:35-64. 2013
    ..Here, we review the phases of brain development, how factors influence brain, and behavioral development in both the normal and perturbed brain, and propose mechanisms that may underlie these effects. ..
  15. doi request reprint Brain plasticity and recovery from early cortical injury
    Bryan Kolb
    Department of Neuroscience, University of Lethbridge, Alberta, Canada
    Dev Med Child Neurol 53:4-8. 2011
    ..All these factors influence cerebral development and influence recovery from brain injury during development...