J M Murkin

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Near-infrared spectroscopy as an index of brain and tissue oxygenation
    J M Murkin
    Department of Anesthesiology and Perioperative Medicine, University Hospital LHSC, University of Western Ontario, Rm C3 112, 339 Windermere Rd, London, ON, Canada N6A 5A5
    Br J Anaesth 103:i3-13. 2009
  2. ncbi Monitoring brain oxygen saturation during coronary bypass surgery improves outcomes in diabetic patients: a post hoc analysis
    John M Murkin
    Department of Anesthesiology and Perioperative Medicine, University of Western Ontario, University Hospital Campus LHSC, 339 Windermere Road, London, Ontario, Canada
    Heart Surg Forum 14:E1-6. 2011
  3. ncbi Panvascular inflammation and mechanisms of injury in perioperative CNS outcomes
    John M Murkin
    University of Western Ontario, London, ON, Canada
    Semin Cardiothorac Vasc Anesth 14:190-5. 2010
  4. ncbi Lessons learned in antifibrinolytic therapy: The BART trial
    John M Murkin
    London Health Sciences Center, University of Western Ontario, London, Ontario, Canada
    Semin Cardiothorac Vasc Anesth 13:127-31. 2009
  5. ncbi Beating heart surgery: why expect less central nervous system morbidity?
    J M Murkin
    Department of Anaesthesia, University Campus, London Health Sciences Center, Ontario, Canada
    Ann Thorac Surg 68:1498-501. 1999
  6. ncbi Attenuation of neurologic injury during cardiac surgery
    J M Murkin
    Department of Anesthesiology and Perioperative Medicine, London Health Sciences Center, University of Western Ontario, Canada
    Ann Thorac Surg 72:S1838-44. 2001
  7. ncbi High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients
    John M Murkin
    Department of Anesthesiology and Perioperative Medicine, University Hospital LHSC, University of Western Ontario, London, Ontario, Canada
    Anesth Analg 110:350-3. 2010
  8. ncbi Cognitive dysfunction after ventricular fibrillation during implantable cardiovertor/defibrillator procedures is related to duration of the reperfusion interval
    J M Murkin
    Department of Anaesthesia, London Health Sciences Centre, University of Western Ontario, Canada
    Anesth Analg 84:1186-92. 1997
  9. ncbi Beating heart surgery or conventional CABG: are neurologic outcomes different?
    I Iglesias
    Department of Cardiac Anesthesiology, University Hospital Campus LHSC, University of Western Ontario, London, Ontario, Canada
    Semin Thorac Cardiovasc Surg 13:158-69. 2001
  10. ncbi Genetic susceptibility to inflammatory injury and various adverse outcomes
    John M Murkin
    University of Western Ontario, London, Ontario, Canada
    J Extra Corpor Technol 41:P43-9. 2009

Detail Information

Publications22

  1. ncbi Near-infrared spectroscopy as an index of brain and tissue oxygenation
    J M Murkin
    Department of Anesthesiology and Perioperative Medicine, University Hospital LHSC, University of Western Ontario, Rm C3 112, 339 Windermere Rd, London, ON, Canada N6A 5A5
    Br J Anaesth 103:i3-13. 2009
    ..This review provides a synopsis of the mode of operation, current limitations and confounders, clinical applications, and potential future uses of such NIRS devices...
  2. ncbi Monitoring brain oxygen saturation during coronary bypass surgery improves outcomes in diabetic patients: a post hoc analysis
    John M Murkin
    Department of Anesthesiology and Perioperative Medicine, University of Western Ontario, University Hospital Campus LHSC, 339 Windermere Road, London, Ontario, Canada
    Heart Surg Forum 14:E1-6. 2011
    ....
  3. ncbi Panvascular inflammation and mechanisms of injury in perioperative CNS outcomes
    John M Murkin
    University of Western Ontario, London, ON, Canada
    Semin Cardiothorac Vasc Anesth 14:190-5. 2010
    ..Finally, a summary of recommendations for strategies to decrease risk of perioperative CNS impairment will be presented...
  4. ncbi Lessons learned in antifibrinolytic therapy: The BART trial
    John M Murkin
    London Health Sciences Center, University of Western Ontario, London, Ontario, Canada
    Semin Cardiothorac Vasc Anesth 13:127-31. 2009
    ..This article will briefly review these developments with the hope of understanding how this abrupt turnabout took place and will attempt to understand how such events can be avoided in the future...
  5. ncbi Beating heart surgery: why expect less central nervous system morbidity?
    J M Murkin
    Department of Anaesthesia, University Campus, London Health Sciences Center, Ontario, Canada
    Ann Thorac Surg 68:1498-501. 1999
    ..The incidence and etiology of brain dysfunction after conventional coronary artery bypass surgery using cardiopulmonary bypass (CPB) are reviewed...
  6. ncbi Attenuation of neurologic injury during cardiac surgery
    J M Murkin
    Department of Anesthesiology and Perioperative Medicine, London Health Sciences Center, University of Western Ontario, Canada
    Ann Thorac Surg 72:S1838-44. 2001
    ..Meta-analysis of the large North American aprotinin database of prospective, randomized, placebo-controlled clinical trials is suggestive of a cerebroprotective potential associated with high-dose aprotinin administration...
  7. ncbi High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients
    John M Murkin
    Department of Anesthesiology and Perioperative Medicine, University Hospital LHSC, University of Western Ontario, London, Ontario, Canada
    Anesth Analg 110:350-3. 2010
    ..The purpose of this review was to perform a retrospective analysis to examine whether there was a relation between TXA usage and seizures after cardiac surgery...
  8. ncbi Cognitive dysfunction after ventricular fibrillation during implantable cardiovertor/defibrillator procedures is related to duration of the reperfusion interval
    J M Murkin
    Department of Anaesthesia, London Health Sciences Centre, University of Western Ontario, Canada
    Anesth Analg 84:1186-92. 1997
    ..We conclude that cognitive dysfunction can occur after insertion of ICD and is related to the duration of RI...
  9. ncbi Beating heart surgery or conventional CABG: are neurologic outcomes different?
    I Iglesias
    Department of Cardiac Anesthesiology, University Hospital Campus LHSC, University of Western Ontario, London, Ontario, Canada
    Semin Thorac Cardiovasc Surg 13:158-69. 2001
    ..Definitive conclusions regarding outcomes after best practice CPB or BHS await large-scale, risk-stratisfied multicenter trials...
  10. ncbi Genetic susceptibility to inflammatory injury and various adverse outcomes
    John M Murkin
    University of Western Ontario, London, Ontario, Canada
    J Extra Corpor Technol 41:P43-9. 2009
    ..This review will provide a brief overview of genetic studies and the interaction between phenotype and individual patient susceptibilities with a focus on cardiac surgical procedures...
  11. ncbi Stress and inflammatory response after beating heart surgery versus conventional bypass surgery: the role of thoracic epidural anesthesia
    S Ganapathy
    Departments of Anesthesiology and Perioperative Medicine, London Health Sciences Centre, University Campus, University of Western Ontario, Canada
    Heart Surg Forum 4:323-7. 2001
    ..Thoracic epidural analgesia inhibits intraoperative cortisol as well as catecholamine surge but does not add further to the reduction in cytokine response [Ganapathy 1999b]...
  12. ncbi Applied neuromonitoring and improving central nervous system outcomes
    John M Murkin
    Department of Anesthesia and Perioperative Medicine, University of Western Ontario, London, Ontario, Canada
    Artif Organs 32:851-5. 2008
    ..The role of transesophageal echocardiography for assessment of ascending aortic atherosclerosis and the use of noninvasive cerebral oximetry to detect cerebral hypoperfusion are discussed with respect to their impact on patient outcomes...
  13. ncbi Perioperative multimodality neuromonitoring: an overview
    John M Murkin
    London Health Sciences Center, University of Western Ontario, Ontario, Canada
    Semin Cardiothorac Vasc Anesth 8:167-71. 2004
    ..These neuromonitoring methods, particularly when used in concert, can improve overall patient outcome and reduce hospital length of stay...
  14. ncbi The role of recombinant factor VIIa in on-pump cardiac surgery: proceedings of the Canadian Consensus Conference
    Keyvan Karkouti
    University Health Network, Toronto General Hospital, Department of Anesthesia, Toronto, Ontario, Canada
    Can J Anaesth 54:573-82. 2007
    ..A Canadian Consensus Conference was convened to generate recommendations for rFVIIa use in on-pump cardiac surgery...
  15. ncbi Hemodynamic changes during cardiac manipulation in off-CPB surgery: relevance in brain perfusion
    John M Murkin
    Anesthesiology, University of Western Ontario, London, Ontario, Canada
    Heart Surg Forum 5:221-4. 2002
    ..We conclude that for cardiac surgery patients considered at increased risk of adverse central nervous system events, direct monitoring of cerebral function and avoidance of aortic manipulation is strongly recommended...
  16. ncbi A novel hemostatic agent: the potential role of recombinant activated factor VII (rFVIIa) in anesthetic practice
    John M Murkin
    Department of Anesthesiology, University of Western Ontario, London, Canada
    Can J Anaesth 49:S21-6. 2002
    ..To review the role of recombinant factor VIIa in anesthetic practice...
  17. ncbi Transfusion trigger Hct 25%: above or below, which is better? Pro: Hct <25% is better
    John M Murkin
    University of Western Ontario, London, Ontario, Canada
    J Cardiothorac Vasc Anesth 18:234-7. 2004
  18. ncbi Neurologic complications in noncardiac surgery
    John M Murkin
    Department of Anesthesiology and Perioperative Medicine, University Campus LHSC, London, Ontario, Canada
    Semin Cardiothorac Vasc Anesth 10:125-7. 2006
    ....
  19. ncbi Pathophysiological basis of CNS injury in cardiac surgical patients: detection and prevention
    John M Murkin
    University of Western Ontario, London, Ont, Canada
    Perfusion 21:203-8. 2006
    ..In this review a number of these factors and their potential interactions will be explored with a view towards developing a comprehensive management strategy to minimize CNS injury...
  20. ncbi Inflammatory responses and CNS injury: implications, prophylaxis, and treatment
    John M Murkin
    Department of Anesthesiology and Perioperative Medicine, London Health Sciences Center, University of Western Ontario, London, Ontario, Canada
    Heart Surg Forum 6:193-5. 2003
    ..Treatment with hyperbaric oxygen therapy was successful in this case...
  21. ncbi Applied neuromonitoring in cardiac surgery: patient specific management
    Nousheh Saidi
    Department of Anesthesiology and Perioperative Medicine (Clinical Fellow, University of Western Ontario, London, Ontario
    Semin Cardiothorac Vasc Anesth 9:17-23. 2005
    ..Recent outcomes data regarding CNS and related morbidity and the influence of neuromonitoring in these groups are evaluated...
  22. ncbi Applied neuromonitoring and improving CNS outcomes
    John M Murkin
    University of Western Ontario, London, Ontario, Canada
    Semin Cardiothorac Vasc Anesth 9:139-42. 2005
    ..Overall patient outcomes can be improved, and hospital length of stay shortened, by applied neuromonitoring techniques...