R T Mullen

Summary

Affiliation: University of Guelph
Country: Canada

Publications

  1. pmc Localization of the Carnation Italian ringspot virus replication protein p36 to the mitochondrial outer membrane is mediated by an internal targeting signal and the TOM complex
    Yeen Ting Hwang
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    BMC Cell Biol 9:54. 2008
  2. pmc The peroxisomal multifunctional protein interacts with cortical microtubules in plant cells
    Simon D X Chuong
    Department of Biological Sciences, University of Calgary, Calgary, AB, T2N 1N4, Canada
    BMC Cell Biol 6:40. 2005
  3. ncbi request reprint How are peroxisomes formed? The role of the endoplasmic reticulum and peroxins
    R T Mullen
    Dept Botany, University of Guelph, N1G 2W1, Guelph, Ontario, Canada
    Trends Plant Sci 6:256-61. 2001
  4. ncbi request reprint The ER-peroxisome connection in plants: development of the "ER semi-autonomous peroxisome maturation and replication" model for plant peroxisome biogenesis
    Robert T Mullen
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada N1G 2W1
    Biochim Biophys Acta 1763:1655-68. 2006
  5. pmc Localization of the tomato bushy stunt virus replication protein p33 reveals a peroxisome-to-endoplasmic reticulum sorting pathway
    Andrew W McCartney
    Department of Molecular and Cellular Biology, University of Guelph, Ontario, Canada
    Plant Cell 17:3513-31. 2005
  6. pmc Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondria
    Yeen Ting Hwang
    Department of Botany, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Plant Cell 16:3002-19. 2004
  7. doi request reprint Arabidopsis thaliana GPAT8 and GPAT9 are localized to the ER and possess distinct ER retrieval signals: functional divergence of the dilysine ER retrieval motif in plant cells
    Satinder K Gidda
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Plant Physiol Biochem 47:867-79. 2009
  8. pmc Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate
    Shawn M Clark
    Department of Plant Agriculture, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    J Exp Bot 60:3255-67. 2009
  9. pmc Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate
    Shawn M Clark
    Department of Plant Agriculture, University of Guelph, Guelph, Ontario, Canada
    J Exp Bot 60:1743-57. 2009
  10. doi request reprint Increased nitrogen-use efficiency in transgenic rice plants over-expressing a nitrogen-responsive early nodulin gene identified from rice expression profiling
    Yong Mei Bi
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada N1G 2W1
    Plant Cell Environ 32:1749-60. 2009

Collaborators

  • Feng Ming
  • Barry J Shelp
  • J M Dyer
  • Yeen Ting Hwang
  • A Baker
  • Jennifer Lippincott-Schwartz
  • Shawn M Clark
  • Rosa Di Leo
  • Simon D X Chuong
  • Steven J Rothstein
  • Satinder K Gidda
  • Preetinder K Dhanoa
  • Jay M Shockey
  • Brenden A Hurley
  • Yong Mei Bi
  • Owen R Van Cauwenberghe
  • George W Bassel
  • Jeffrey P Simpson
  • Matthew P A Henderson
  • Vladimir I Titorenko
  • Peter K Kim
  • Andrew W McCartney
  • Douglas G Muench
  • Sophia L Stone
  • Mary A Murphy
  • Naomi J Marty
  • Joonho Park
  • William C Plaxton
  • Hue T Tran
  • Wayne A Snedden
  • Joseph Clark
  • Joseph Clarke
  • Amanda Rochon
  • Lixin Hao
  • Tong Zhu
  • Satinder Gidda
  • Rong Zhao
  • Surya Kant
  • Jianyao Xu
  • J Derek Bewley
  • Gordon J Hoover
  • Wendy L Allan
  • Amina Makhmoudova
  • David W Andrews
  • John M Bland
  • Uwe Schumann
  • Dorselyn C Chapital
  • Jui Chang Kuan
  • K Andrew White
  • John S Greenwood
  • Nam Il Park
  • Marc R Fabian
  • Michelle C Freeman
  • Daphne R Goring
  • Belinda A Phillipson
  • Erin M Anderson

Detail Information

Publications21

  1. pmc Localization of the Carnation Italian ringspot virus replication protein p36 to the mitochondrial outer membrane is mediated by an internal targeting signal and the TOM complex
    Yeen Ting Hwang
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    BMC Cell Biol 9:54. 2008
    ....
  2. pmc The peroxisomal multifunctional protein interacts with cortical microtubules in plant cells
    Simon D X Chuong
    Department of Biological Sciences, University of Calgary, Calgary, AB, T2N 1N4, Canada
    BMC Cell Biol 6:40. 2005
    ..In addition to these peroxisomal activities, in vitro assays revealed that rice MFP possesses microtubule- and RNA-binding activities suggesting that this protein also has important functions in the cytosol...
  3. ncbi request reprint How are peroxisomes formed? The role of the endoplasmic reticulum and peroxins
    R T Mullen
    Dept Botany, University of Guelph, N1G 2W1, Guelph, Ontario, Canada
    Trends Plant Sci 6:256-61. 2001
    ..Within this context, we discuss the proposed role for the endoplasmic reticulum in the formation of preperoxisomes and the potential for 15 Arabidopsis peroxin homologs to function in the biogenesis of peroxisomes in plant cells...
  4. ncbi request reprint The ER-peroxisome connection in plants: development of the "ER semi-autonomous peroxisome maturation and replication" model for plant peroxisome biogenesis
    Robert T Mullen
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada N1G 2W1
    Biochim Biophys Acta 1763:1655-68. 2006
    ..In addition, new plant peroxisomes are envisaged to arise primarily by duplication of the pre-existing peroxisomes that receive essential membrane components from the ER...
  5. pmc Localization of the tomato bushy stunt virus replication protein p33 reveals a peroxisome-to-endoplasmic reticulum sorting pathway
    Andrew W McCartney
    Department of Molecular and Cellular Biology, University of Guelph, Ontario, Canada
    Plant Cell 17:3513-31. 2005
    ..These results provide insight into virus-induced intracellular rearrangements and reveal a peroxisome-to-pER sorting pathway, raising new mechanistic questions regarding the biogenesis of peroxisomes in plants...
  6. pmc Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondria
    Yeen Ting Hwang
    Department of Botany, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Plant Cell 16:3002-19. 2004
    ..Collectively, the results presented provide significant insight into the early biogenetic events required for entry of tail-anchored proteins into either the ER or mitochondrial targeting pathways...
  7. doi request reprint Arabidopsis thaliana GPAT8 and GPAT9 are localized to the ER and possess distinct ER retrieval signals: functional divergence of the dilysine ER retrieval motif in plant cells
    Satinder K Gidda
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Plant Physiol Biochem 47:867-79. 2009
    ....
  8. pmc Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate
    Shawn M Clark
    Department of Plant Agriculture, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    J Exp Bot 60:3255-67. 2009
    ..Overall, these findings, together with recent information about rice and pepper GABA-Ts, indicate that the subcellular distribution of GABA-T in the plant kingdom is highly variable...
  9. pmc Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate
    Shawn M Clark
    Department of Plant Agriculture, University of Guelph, Guelph, Ontario, Canada
    J Exp Bot 60:1743-57. 2009
    ..A GABA-T with dual functions suggests the potential for interaction between GABA metabolism and photorespiratory glyoxylate production...
  10. doi request reprint Increased nitrogen-use efficiency in transgenic rice plants over-expressing a nitrogen-responsive early nodulin gene identified from rice expression profiling
    Yong Mei Bi
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada N1G 2W1
    Plant Cell Environ 32:1749-60. 2009
    ..This work demonstrates that transcriptional profiling, coupled with a transgenic validation approach, is an effective strategy for gene discovery. The knowledge gained from this study could be applied to other important crops...
  11. pmc Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification
    Jeffrey P Simpson
    Department of Plant Agriculture, University of Guelph, Guelph, Ontario, Canada
    J Exp Bot 59:2545-54. 2008
    ..The identification and characterization of distinct plastidial and cytosolic glyoxylate reductase isoforms is discussed with respect to aldehyde detoxification and the plant stress response...
  12. doi request reprint Procera is a putative DELLA mutant in tomato (Solanum lycopersicum): effects on the seed and vegetative plant
    George W Bassel
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada, N1G 2W1
    J Exp Bot 59:585-93. 2008
    ..Transient expression of a LeGAI-GFP (green fluorescent protein) fusion protein in onion epidermis results in its location to the nucleus, and this protein is rapidly degraded by the proteasome in the presence of GA...
  13. pmc The dual-targeted purple acid phosphatase isozyme AtPAP26 is essential for efficient acclimation of Arabidopsis to nutritional phosphate deprivation
    Brenden A Hurley
    Department of Biology, Queen s University, Kingston, Ontario, Canada
    Plant Physiol 153:1112-22. 2010
    ..Our results confirm that AtPAP26 is a principal contributor to Pi stress-inducible APase activity, and that it plays an important role in the Pi metabolism of -Pi Arabidopsis...
  14. pmc Characterization of the targeting signal of the Arabidopsis 22-kD integral peroxisomal membrane protein
    Mary A Murphy
    Department of Botany, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Plant Physiol 133:813-28. 2003
    ....
  15. pmc The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER
    Peter K Kim
    Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    J Cell Biol 173:521-32. 2006
    ..Finally, we demonstrate that the increase in peroxisome number in growing wild-type cells results primarily from new peroxisomes derived from the ER rather than by division of preexisting peroxisomes...
  16. doi request reprint Engineering plant oils as high-value industrial feedstocks for biorefining: the need for underpinning cell biology research
    John M Dyer
    United States Department of Agriculture, Agricultural Research Service, US Arid Land Agricultural Research Center, 21881 North Cardon Lane, Maricopa, AZ 85238, USA
    Physiol Plant 132:11-22. 2008
    ....
  17. pmc Tung tree DGAT1 and DGAT2 have nonredundant functions in triacylglycerol biosynthesis and are localized to different subdomains of the endoplasmic reticulum
    Jay M Shockey
    U S Department of Agriculture, Agricultural Research Service, Southern Regional Research Center, New Orleans, Louisiana 70124, USA
    Plant Cell 18:2294-313. 2006
    ..These data suggest that DGAT1 and DGAT2 have nonredundant functions in plants and that the production of storage oils, including those containing unusual fatty acids, occurs in distinct ER subdomains...
  18. pmc Peroxisome biogenesis: the peroxisomal endomembrane system and the role of the ER
    Vladimir I Titorenko
    Department of Biology, Concordia University, Montreal, Quebec H4B 1R6, Canada
    J Cell Biol 174:11-7. 2006
    ....
  19. pmc ARC1 is an E3 ubiquitin ligase and promotes the ubiquitination of proteins during the rejection of self-incompatible Brassica pollen
    Sophia L Stone
    Department of Botany, University of Toronto, Toronto, Ontario, Canada M5S 3B2
    Plant Cell 15:885-98. 2003
    ..We propose that ARC1 promotes the ubiquitination and proteasomal degradation of compatibility factors in the pistil, which in turn leads to pollen rejection...
  20. ncbi request reprint Identification of a rice RNA- and microtubule-binding protein as the multifunctional protein, a peroxisomal enzyme involved in the beta -oxidation of fatty acids
    Simon D X Chuong
    Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada
    J Biol Chem 277:2419-29. 2002
    ....
  21. pmc The C-terminus of cytochrome b5 confers endoplasmic reticulum specificity by preventing spontaneous insertion into membranes
    Matthew P A Henderson
    Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada L8N 3Z5
    Biochem J 401:701-9. 2007
    ..Our results indicate that the CTSs from plant Cb5 proteins provide ER specificity by preventing spontaneous insertion into incorrect subcellular membranes...