G D Muir

Summary

Affiliation: University of Saskatchewan
Country: Canada

Publications

  1. ncbi request reprint Early ontogeny of locomotor behaviour: a comparison between altricial and precocial animals
    G D Muir
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Brain Res Bull 53:719-26. 2000
  2. ncbi request reprint Role of motor and visual experience during development of bipedal locomotion in chicks
    Gillian D Muir
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada
    J Neurophysiol 94:3691-7. 2005
  3. ncbi request reprint Dorsolateral cervical spinal injury differentially affects forelimb and hindlimb action in rats
    Gillian D Muir
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, SK, Canada S7N 5B4
    Eur J Neurosci 25:1501-10. 2007
  4. ncbi request reprint Locomotor plasticity after spinal injury in the chick
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Canada
    J Neurotrauma 16:705-11. 1999
  5. ncbi request reprint Red nucleus lesions impair overground locomotion in rats: a kinetic analysis
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Eur J Neurosci 12:1113-22. 2000
  6. ncbi request reprint Mini-review: assessment of behavioural recovery following spinal cord injury in rats
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Canada S7N 5B4
    Eur J Neurosci 12:3079-86. 2000
  7. ncbi request reprint Behavioural analysis of the efficacy of treatments for injuries to the spinal cord in animals
    A A Webb
    Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, University of Saskatchewan, Saskatoon, SK, Canada S7N 5B4
    Vet Rec 155:225-30. 2004
  8. ncbi request reprint Course of motor recovery following ventrolateral spinal cord injury in the rat
    Aubrey A Webb
    Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Sask, Canada S7N 5B4
    Behav Brain Res 155:55-65. 2004
  9. ncbi request reprint Ground reaction forces in locomoting hemi-parkinsonian rats: a definitive test for impairments and compensations
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatooon, Canada
    Exp Brain Res 126:307-14. 1999
  10. ncbi request reprint The blood-brain barrier and its role in inflammation
    A A Webb
    Department of Veterinary Physiological Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada
    J Vet Intern Med 14:399-411. 2000

Detail Information

Publications23

  1. ncbi request reprint Early ontogeny of locomotor behaviour: a comparison between altricial and precocial animals
    G D Muir
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Brain Res Bull 53:719-26. 2000
    ..Therefore, components of locomotor behaviour involving the maintenance of equilibrium need a period of maturation in both precocial and altricial species, possibly requiring locomotor experience to become fully mature...
  2. ncbi request reprint Role of motor and visual experience during development of bipedal locomotion in chicks
    Gillian D Muir
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada
    J Neurophysiol 94:3691-7. 2005
    ..These results are discussed along with related findings in other species and the possible neural and biomechanical constraints underlying development of walking and head bobbing in birds...
  3. ncbi request reprint Dorsolateral cervical spinal injury differentially affects forelimb and hindlimb action in rats
    Gillian D Muir
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, SK, Canada S7N 5B4
    Eur J Neurosci 25:1501-10. 2007
    ..We discuss these findings in relation to previous work and to the possible contributions of different ascending and descending pathways in the DLF to locomotion and skilled movements in rats...
  4. ncbi request reprint Locomotor plasticity after spinal injury in the chick
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Canada
    J Neurotrauma 16:705-11. 1999
    ..It is concluded that the spinal cord has significant plastic capabilities, and efforts should be directed toward maximizing the contribution of this plasticity to functional recovery after spinal cord injury...
  5. ncbi request reprint Red nucleus lesions impair overground locomotion in rats: a kinetic analysis
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Eur J Neurosci 12:1113-22. 2000
    ..Species differences in phylogeny and connectivity of the red nucleus are discussed, as well as the possibility that there is a general compensatory response to unilateral CNS injury in the rat...
  6. ncbi request reprint Mini-review: assessment of behavioural recovery following spinal cord injury in rats
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Canada S7N 5B4
    Eur J Neurosci 12:3079-86. 2000
    ..Finally, we make some recommendations regarding the principles for a comprehensive behavioural analysis after experimental spinal cord injury in rats...
  7. ncbi request reprint Behavioural analysis of the efficacy of treatments for injuries to the spinal cord in animals
    A A Webb
    Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, University of Saskatchewan, Saskatoon, SK, Canada S7N 5B4
    Vet Rec 155:225-30. 2004
    ....
  8. ncbi request reprint Course of motor recovery following ventrolateral spinal cord injury in the rat
    Aubrey A Webb
    Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Sask, Canada S7N 5B4
    Behav Brain Res 155:55-65. 2004
    ..These results suggest that axons in the ventrolateral spinal funiculi contribute to limb movements during exploration and locomotion but their roles can be served by other pathways after ventrolateral spinal injury...
  9. ncbi request reprint Ground reaction forces in locomoting hemi-parkinsonian rats: a definitive test for impairments and compensations
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatooon, Canada
    Exp Brain Res 126:307-14. 1999
    ..These results demonstrate that this method is useful in the analysis of hemi-parkinsonian gait and provide insights as to how rats can use an impaired limb to produce weight support and propulsion...
  10. ncbi request reprint The blood-brain barrier and its role in inflammation
    A A Webb
    Department of Veterinary Physiological Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada
    J Vet Intern Med 14:399-411. 2000
    ..This review focusses on recent discoveries about the BBB and its role in inflammation, and applies this knowledge to our current understanding of inflammatory CNS disease in dogs and cats...
  11. ncbi request reprint Asymmetric bipedal locomotion--an adaptive response to incomplete spinal injury in the chick
    G D Muir
    Department of Zoology, University of British Columbia, Vancouver, Canada
    Exp Brain Res 122:275-82. 1998
    ....
  12. ncbi request reprint The differential effects of cervical and thoracic dorsal funiculus lesions in rats
    Srikanth G Kanagal
    Department of Biomedical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada
    Behav Brain Res 187:379-86. 2008
    ..These findings have implications for the mechanisms of recovery as well as the types of behavioural tests which can be practically used to measure functional changes in different lesion models...
  13. ncbi request reprint Bilateral dorsal funicular lesions alter sensorimotor behaviour in rats
    Srikanth G Kanagal
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan Saskatoon, Canada SK S7N 5B4
    Exp Neurol 205:513-24. 2007
    ..These results also illustrate the value of using sensitive methods to reveal detailed behavioural changes after spinal injury...
  14. doi request reprint Effects of combined dorsolateral and dorsal funicular lesions on sensorimotor behaviour in rats
    Srikanth G Kanagal
    Department of Biomedical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, University of Saskatchewan, Saskatoon, SK, Canada S7N 5B4
    Exp Neurol 214:229-39. 2008
    ....
  15. ncbi request reprint Sensorimotor behaviour following incomplete cervical spinal cord injury in the rat
    Aubrey A Webb
    Canadian Institutes of Health Research Post doctoral Fellow, Department of Biomedical Sciences, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, PEI, Canada C1A 4P3
    Behav Brain Res 165:147-59. 2005
    ..We also provide insight into the neuroanatomic substrates important for performing a given behaviour, information which may prove essential in the development of site-directed therapeutic strategies...
  16. ncbi request reprint Fischer (F-344) rats have different morphology, sensorimotor and locomotor abilities compared to Lewis, Long-Evans, Sprague-Dawley and Wistar rats
    Aubrey A Webb
    Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5B4
    Behav Brain Res 144:143-56. 2003
    ..We conclude that morphologic, sensory and motor differences exist between the five strains of laboratory rats examined and several of these differences are most pronounced in the Fischer strain...
  17. ncbi request reprint Unilateral dorsal column and rubrospinal tract injuries affect overground locomotion in the unrestrained rat
    Aubrey A Webb
    Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, University of Saskatchewan, Saskatoon, SK, Canada
    Eur J Neurosci 18:412-22. 2003
    ..Additionally, the ascending dorsal column pathways and the rubrospinal tract play a role during flat surface overground locomotion and combined damage to these pathways does not alter the acquired gait...
  18. ncbi request reprint Steroid-responsive meningitis-arteritis in dogs with noninfectious, nonerosive, idiopathic, immune-mediated polyarthritis
    Aubrey A Webb
    Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada
    J Vet Intern Med 16:269-73. 2002
    ..We concluded that SRMA does occur concurrently in some dogs having IMPA. Meningeal involvement may explain the origin of spinal pain observed in some of these dogs...
  19. ncbi request reprint Compensatory locomotor adjustments of rats with cervical or thoracic spinal cord hemisections
    Aubrey A Webb
    Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, Saskatoon, Saskatchewan, Canada
    J Neurotrauma 19:239-56. 2002
    ..We conclude that rats develop a general compensatory response for unilateral CNS lesions, which may help stabilize the animal during locomotion...
  20. doi request reprint Task-dependent compensation after pyramidal tract and dorsolateral spinal lesions in rats
    Srikanth G Kanagal
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada
    Exp Neurol 216:193-206. 2009
    ..These differential responses suggest that behavioural tasks vary in their reliance on specific pathways after injury, and, furthermore, that compensation for loss of specific connections can arise from numerous sources...
  21. ncbi request reprint Posthatching locomotor experience alters locomotor development in chicks
    G D Muir
    Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4, Canada
    J Neurophysiol 88:117-23. 2002
    ..These results are discussed in terms of the possible neuroanatomical and neurophysiological mechanisms underlying experience- and activity-dependent changes during motor development...
  22. ncbi request reprint Complete locomotor recovery following corticospinal tract lesions: measurement of ground reaction forces during overground locomotion in rats
    G D Muir
    Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Canada
    Behav Brain Res 103:45-53. 1999
    ..Complete recovery from corticospinal tract transection provides unequivocal evidence that input from the corticospinal tract is not essential for normal overground locomotion in the rat...
  23. ncbi request reprint Treadmill training ameliorates dopamine loss but not behavioral deficits in hemi-parkinsonian rats
    Nadine P Poulton
    Biomedical Sciences, WCVM, University of Saskatchewan, 52 Campus Drive, Saskatoon, SK, Canada S7N 5B4
    Exp Neurol 193:181-97. 2005
    ..We conclude that treadmill training does not ameliorate locomotor deficits in the 6-OHDA model of Parkinson's disease, even though this same training results in attenuation of dopamine loss in the striatum...