Mario A Monteiro

Summary

Affiliation: University of Guelph
Country: Canada

Publications

  1. ncbi request reprint Phase-variation of the truncated lipo-oligosaccharide of Neisseria meningitidis NMB phosphoglucomutase isogenic mutant NMB-R6
    Mario A Monteiro
    Wyeth Vaccines Research, 211 Bailey Road, West Henrietta, NY 14586, USA
    Carbohydr Res 338:2905-12. 2003
  2. ncbi request reprint A novel Helicobacter pylori cell-surface polysaccharide
    Stacey Britton
    Department of Chemistry, University of Guelph, Guelph, ON N1G 2W1, Canada
    Carbohydr Res 340:1605-11. 2005
  3. doi request reprint A polysaccharide of Alloiococcus otitidis, a new pathogen of otitis media: chemical structure and synthesis of a neoglycoconjugate thereof
    Sharif Arar
    Department of Chemistry, University of Guelph, Guelph, ON, Canada N1G 2W1
    Carbohydr Res 343:1079-90. 2008
  4. doi request reprint Carbohydrate-based Clostridium difficile vaccines
    Mario A Monteiro
    University of Guelph, Guelph, ON, N1G 2W1, Canada
    Expert Rev Vaccines 12:421-31. 2013
  5. doi request reprint Synthesis and immunogenicity of a Helicobacter pylori lipopolysaccharide-based conjugate
    Mario A Monteiro
    Department of Chemistry, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Vaccine 29:3098-102. 2011
  6. doi request reprint Discovery and characterization of a fructosylated capsule polysaccharide and sialylated lipopolysaccharide in a virulent strain of Actinobacillus suis
    Rudolf Deutschmann
    Department of Chemistry, University of Guelph, Canada
    Biochem Cell Biol 89:325-31. 2011
  7. doi request reprint The lipopolysaccharide core of Actinobacillus suis and its relationship to those of Actinobacillus pleuropneumoniae
    Jeyabarathy Ganeshapillai
    Department of Chemistry, University of Guelph, Canada
    Biochem Cell Biol 89:351-8. 2011
  8. doi request reprint Clostridium difficile PSI polysaccharide: synthesis of pentasaccharide repeating block, conjugation to exotoxin B subunit, and detection of natural anti-PSI IgG antibodies in horse serum
    Yuening Jiao
    Department of Chemistry, University of Guelph, Guelph, ON, Canada
    Carbohydr Res 378:15-25. 2013
  9. doi request reprint Clostridium difficile carbohydrates: glucan in spores, PSII common antigen in cells, immunogenicity of PSII in swine and synthesis of a dual C. difficile-ETEC conjugate vaccine
    Lisa Bertolo
    Department of Chemistry, University of Guelph, Guelph, ON, Canada
    Carbohydr Res 354:79-86. 2012
  10. pmc Mutation of waaC, encoding heptosyltransferase I in Campylobacter jejuni 81-176, affects the structure of both lipooligosaccharide and capsular carbohydrate
    Margaret I Kanipes
    Department of Chemistry, North Carolina Agricultural and Technical State University, Greensboro, North Carolina 27411, USA
    J Bacteriol 188:3273-9. 2006

Collaborators

  • Patricia Guerry
  • Gayatri Vedantam
  • J Scott Weese
  • Shahida Baqar
  • Janet I MacInnes
  • Shayan Sharif
  • Craig T Parker
  • Evgeny Vinogradov
  • Jianjun Li
  • David E Bentzel
  • Clifford W Beninger
  • Michael St Paul
  • C Whitfield
  • Adam Choma
  • Lisa Bertolo
  • Sharif Arar
  • Zuchao Ma
  • Alexander G Boncheff
  • Margaret I Kanipes
  • Rudolf Deutschmann
  • Jeyabarathy Ganeshapillai
  • Erzsebet Papp-Szabo
  • Brittany Pequegnat
  • Yu Han Chen
  • Natalia A Kaniuk
  • Yuening Jiao
  • Neda Barjesteh
  • Frederic Poly
  • Frank St Michael
  • Jianqiang Zhao
  • Anthony Rullo
  • Stacey Britton
  • Kenneth H Chan
  • Douglas C Hodgins
  • Emma Allen-Vercoe
  • Wanderley M Quinteiro-Filho
  • Herbert Chow
  • Moez Valliani
  • Luis Arroyo
  • Christina Depass
  • Michael Toh
  • Cheryl P Ewing
  • Martin Sagermann
  • Doug Hodgins
  • Alexander Maue
  • Joyce Rosseau
  • Terra Wakeford
  • Michele Chu
  • Robert M Friendship
  • Michael Mallozzi
  • Durda Slavic
  • Loredana Daraban
  • Xuan Tan
  • P Lynn Shewmaker
  • Zbigniew Pakulski
  • Joyce Rousseau
  • David Rockabrand
  • Aurel Akelaitis
  • Rudolf O Waelchli
  • Bette A Quinn
  • Keith J Betteridge
  • M Anthony Hayes
  • Diane E Taylor
  • Joanna Simala-Grant
  • Lisa Morrison
  • Warren W Wakarchuk
  • Suzon Larocque
  • Christine M Szymanski
  • Nam Huan Khieu
  • Jean Robert Brisson

Detail Information

Publications27

  1. ncbi request reprint Phase-variation of the truncated lipo-oligosaccharide of Neisseria meningitidis NMB phosphoglucomutase isogenic mutant NMB-R6
    Mario A Monteiro
    Wyeth Vaccines Research, 211 Bailey Road, West Henrietta, NY 14586, USA
    Carbohydr Res 338:2905-12. 2003
    ..A glycoconjugate vaccine comprised of NMB-R6 LOSs is currently being evaluated in our laboratory...
  2. ncbi request reprint A novel Helicobacter pylori cell-surface polysaccharide
    Stacey Britton
    Department of Chemistry, University of Guelph, Guelph, ON N1G 2W1, Canada
    Carbohydr Res 340:1605-11. 2005
    ..These findings revealed the bio-molecular basis for the observed serospecificity of H. pylori serotype O2, and that this unique bacterial PS must be included in the formulation of a multivalent LPS H. pylori vaccine...
  3. doi request reprint A polysaccharide of Alloiococcus otitidis, a new pathogen of otitis media: chemical structure and synthesis of a neoglycoconjugate thereof
    Sharif Arar
    Department of Chemistry, University of Guelph, Guelph, ON, Canada N1G 2W1
    Carbohydr Res 343:1079-90. 2008
    ..otitidis cell-surface carbohydrate and the synthesis of a glycoconjugate preparation thereof. Presently, we are formulating plans to immunologically evaluate this A. otitidis glycoconjugate vaccine in animals...
  4. doi request reprint Carbohydrate-based Clostridium difficile vaccines
    Mario A Monteiro
    University of Guelph, Guelph, ON, N1G 2W1, Canada
    Expert Rev Vaccines 12:421-31. 2013
    ..difficile, respectively; phosphate is an indispensable immunogenic epitope and vaccine-induced PSII antibodies recognize PSII on C. difficile outer surface...
  5. doi request reprint Synthesis and immunogenicity of a Helicobacter pylori lipopolysaccharide-based conjugate
    Mario A Monteiro
    Department of Chemistry, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Vaccine 29:3098-102. 2011
    ..pylori. This study showed that a monovalent H. pylori LPS conjugate can elicit antibodies that recognize other serotype-specific H. pylori LPSs and specifically the structurally conserved LPS inner-regions...
  6. doi request reprint Discovery and characterization of a fructosylated capsule polysaccharide and sialylated lipopolysaccharide in a virulent strain of Actinobacillus suis
    Rudolf Deutschmann
    Department of Chemistry, University of Guelph, Canada
    Biochem Cell Biol 89:325-31. 2011
    ....
  7. doi request reprint The lipopolysaccharide core of Actinobacillus suis and its relationship to those of Actinobacillus pleuropneumoniae
    Jeyabarathy Ganeshapillai
    Department of Chemistry, University of Guelph, Canada
    Biochem Cell Biol 89:351-8. 2011
    ..suis and A. pleuropneumoniae, and the data suggest that the structural epitopes responsible for immunogenicity are those in the outer core domain...
  8. doi request reprint Clostridium difficile PSI polysaccharide: synthesis of pentasaccharide repeating block, conjugation to exotoxin B subunit, and detection of natural anti-PSI IgG antibodies in horse serum
    Yuening Jiao
    Department of Chemistry, University of Guelph, Guelph, ON, Canada
    Carbohydr Res 378:15-25. 2013
    ....
  9. doi request reprint Clostridium difficile carbohydrates: glucan in spores, PSII common antigen in cells, immunogenicity of PSII in swine and synthesis of a dual C. difficile-ETEC conjugate vaccine
    Lisa Bertolo
    Department of Chemistry, University of Guelph, Guelph, ON, Canada
    Carbohydr Res 354:79-86. 2012
    ..Also, with the intent of creating a dual anti-diarrheal vaccine against C. difficile and enterotoxin Escherichia coli (ETEC) infections in humans, we describe the conjugation of PSII to the ETEC-associated LTB enterotoxin...
  10. pmc Mutation of waaC, encoding heptosyltransferase I in Campylobacter jejuni 81-176, affects the structure of both lipooligosaccharide and capsular carbohydrate
    Margaret I Kanipes
    Department of Chemistry, North Carolina Agricultural and Technical State University, Greensboro, North Carolina 27411, USA
    J Bacteriol 188:3273-9. 2006
    ..We also report here the presence of O-methyl phosphoramidate in wild-type strain 81-176 capsular polysaccharide...
  11. doi request reprint Common sialylated glycan in Actinobacillus suis
    Rudolf Deutschmann
    Department of Chemistry, University of Guelph, Guelph, Ontario, Canada
    Glycobiology 20:1227-32. 2010
    ..The ubiquitous expression of this sialylated glycan suggests that this carbohydrate may play an important role in the survival of A. suis in the host...
  12. pmc Capsule polysaccharide conjugate vaccine against diarrheal disease caused by Campylobacter jejuni
    Mario A Monteiro
    Dept of Chemistry, University of Guelph, Guelph, Ontario, Canada
    Infect Immun 77:1128-36. 2009
    ..jejuni. The CPS(81-176)-CRM(197) vaccine also provided 100% protection against diarrhea in the New World monkey Aotus nancymaae following orogastric challenge with C. jejuni 81-176...
  13. doi request reprint The chemical structure and genetic locus of Campylobacter jejuni CG8486 (serotype HS:4) capsular polysaccharide: the identification of 6-deoxy-D-ido-heptopyranose
    Yu Han Chen
    Department of Chemistry, University of Guelph, Guelph, ON, Canada N1G 2W1
    Carbohydr Res 343:1034-40. 2008
    ..jejuni HS:4 CPS complex. The efficacy of a glycoconjugate vaccine based on C. jejuni CG8486 CPS is presently being tested in an animal model, the results of which will be presented in future communications...
  14. pmc Genetic analysis of lipooligosaccharide core biosynthesis in Campylobacter jejuni 81-176
    Margaret I Kanipes
    Department of Chemistry, North Carolina Agricultural and Technical State University, Greensboro, North Carolina 27411, USA
    J Bacteriol 190:1568-74. 2008
    ..These studies have important implications for the role of LOS in the pathogenesis of Campylobacter-mediated infection...
  15. ncbi request reprint Chromosomal and plasmid-encoded enzymes are required for assembly of the R3-type core oligosaccharide in the lipopolysaccharide of Escherichia coli O157:H7
    Natalia A Kaniuk
    Department of Microbiology, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    J Biol Chem 279:31237-50. 2004
    ..coli O157 and Shigella flexneri serotype 2a. This is the first plasmid-encoded core oligosaccharide biosynthesis enzyme reported in E. coli...
  16. doi request reprint The design of a capsule polysaccharide conjugate vaccine against Campylobacter jejuni serotype HS15
    Lisa Bertolo
    Department of Chemistry, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Carbohydr Res 366:45-9. 2013
    ....
  17. doi request reprint Clostridium difficile cell-surface polysaccharides composed of pentaglycosyl and hexaglycosyl phosphate repeating units
    Jeyabarathy Ganeshapillai
    Department of Chemistry, University of Guelph, Guelph, ON, Canada N1G 2W1
    Carbohydr Res 343:703-10. 2008
    ..difficile cell-surface polysaccharides, of which PS-II appears to be a regular C. difficile antigen. These C. difficile teichoic-acid-like polysaccharides will be tested as immunogens in vaccine preparations in a rat and horse model...
  18. doi request reprint TEMPO-mediated glycoconjugation: a scheme for the controlled synthesis of polysaccharide conjugates
    Zuchao Ma
    Department of Chemistry, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Carbohydr Res 346:343-7. 2011
    ....
  19. ncbi request reprint The structural basis for the serospecificity of Actinobacillus suis serogroup O:2
    Anthony Rullo
    Department of Chemistry, University of Guelph, Canada
    Biochem Cell Biol 84:184-90. 2006
    ..suis serogroup O:2 strains is currently underway...
  20. doi request reprint A vaccine and diagnostic target for Clostridium bolteae, an autism-associated bacterium
    Brittany Pequegnat
    Department of Chemistry, University of Guelph, Guelph, ON N1G 2W1, Canada
    Vaccine 31:2787-90. 2013
    ..bolteae colonization of the intestinal tract in autistic patients, and as a diagnostic marker for the rapid detection of C. bolteae in a clinical setting...
  21. doi request reprint Induction of chicken cytokine responses in vivo and in vitro by lipooligosaccharide of Campylobacter jejuni HS:10
    Neda Barjesteh
    Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada
    Vet Microbiol 164:122-30. 2013
    ..More extensive studies with more prolonged exposure to LOS are needed to further clarify the interaction between C. jejuni and the chicken host...
  22. ncbi request reprint Cell-surface alpha-glucan in Campylobacter jejuni 81-176
    Erzsebet Papp-Szabo
    Department of Chemistry, University of Guelph, ON, Canada
    Carbohydr Res 340:2218-21. 2005
    ..Here, we describe that in addition to the LOS and CPS, this strain also produced an independent cell-surface (1-->4)-alpha-glucan capsule...
  23. ncbi request reprint Hydrolysis of bacterial wall carbohydrates in the microwave using trifluoroacetic acid
    Jianqiang Zhao
    Department of Chemistry, University of Guelph, Guelph, ON, Canada N1G 2W1
    Carbohydr Res 343:2498-503. 2008
    ..The results also suggested that non-thermal mechanistic factors must also be involved, at least in part, in accelerating the reaction rate of glycosidic hydrolysis...
  24. ncbi request reprint Desialylation of core type 1 O-glycan in the equine embryonic capsule coincides with immobilization of the conceptus in the uterus
    Sharif Arar
    Department of Chemistry, University of Guelph, Guelph, ON, Canada N1G 2W1
    Carbohydr Res 342:1110-5. 2007
    ..The loss of sialic acid from the sialylated core type 1 in the capsule appears to be directly related to successful fixation of the conceptus, and thus critical to the continuance of pregnancy in horses...
  25. ncbi request reprint The distribution of two major Iridoids in different organs of Antirrhinum majus L. at selected stages of development
    Clifford W Beninger
    Department of Plant Agriculture, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    J Chem Ecol 33:731-47. 2007
    ..However, only (14)C-antirrhinoside was recovered in the subtending petiole tissue, consistent with the suggestion that it is a phloem mobile compound...
  26. ncbi request reprint Molecular diversity of the genetic loci responsible for lipopolysaccharide core oligosaccharide assembly within the genus Salmonella
    Natalia A Kaniuk
    Department of Microbiology, University of Guelph, Guelph, ON, Canada, N1G 2W1
    Mol Microbiol 46:1305-18. 2002
    ....
  27. ncbi request reprint The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168
    Frank St Michael
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Canada
    Eur J Biochem 269:5119-36. 2002
    ..In addition, the correlation of carbohydrate structure with gene complement will aid in the elucidation of the role of these surface carbohydrates in C. jejuni pathogenesis...