Derek G V Mitchell

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Multiple mechanisms of consciousness: the neural correlates of emotional awareness
    Jayna M Amting
    Department of Psychiatry and Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, The University of Western Ontario, 339 Windermere Road, London, Ontario, Canada
    J Neurosci 30:10039-47. 2010
  2. pmc The neural correlates of regulating positive and negative emotions in medication-free major depression
    Steven G Greening
    Brain and Mind Institute, Natural Sciences Building, University of Western Ontario, London, Ontario N6A 5B7, Canada
    Soc Cogn Affect Neurosci 9:628-37. 2014
  3. doi Conscious perception of emotional stimuli: brain mechanisms
    Derek G V Mitchell
    Department of Psychiatry and Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Neuroscientist 18:386-98. 2012
  4. pmc The interference of operant task performance by emotional distracters: an antagonistic relationship between the amygdala and frontoparietal cortices
    D G V Mitchell
    Department of Psychiatry and Department of Anatomy and Cell Biology, The University of Western Ontario, London, Canada
    Neuroimage 40:859-68. 2008
  5. pmc The impact of processing load on emotion
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Neuroimage 34:1299-309. 2007
  6. pmc Adapting to dynamic stimulus-response values: differential contributions of inferior frontal, dorsomedial, and dorsolateral regions of prefrontal cortex to decision making
    Derek G V Mitchell
    National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Neurosci 29:10827-34. 2009
  7. doi The nexus between decision making and emotion regulation: a review of convergent neurocognitive substrates
    Derek G V Mitchell
    Department of Psychiatry and Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, The University of Western Ontario, Canada
    Behav Brain Res 217:215-31. 2011
  8. pmc The contribution of ventrolateral and dorsolateral prefrontal cortex to response reversal
    D G V Mitchell
    Department of Psychiatry, The University of Western Ontario, London, Canada
    Behav Brain Res 187:80-7. 2008
  9. ncbi Emotion-related brain activity to conflicting socio-emotional cues in unmedicated depression
    Steven G Greening
    Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, London, Ontario, Canada
    J Affect Disord 150:1136-41. 2013
  10. doi Reduced amygdala response to fearful expressions in children and adolescents with callous-unemotional traits and disruptive behavior disorders
    Abigail A Marsh
    Mood and Anxiety Program, NIMH, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
    Am J Psychiatry 165:712-20. 2008

Collaborators

Detail Information

Publications29

  1. ncbi Multiple mechanisms of consciousness: the neural correlates of emotional awareness
    Jayna M Amting
    Department of Psychiatry and Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, The University of Western Ontario, 339 Windermere Road, London, Ontario, Canada
    J Neurosci 30:10039-47. 2010
    ..The possibility is raised that interactions between pgPFC and the amygdala, previously implicated in extinction, may also influence whether or not an emotional stimulus is accessible to consciousness...
  2. pmc The neural correlates of regulating positive and negative emotions in medication-free major depression
    Steven G Greening
    Brain and Mind Institute, Natural Sciences Building, University of Western Ontario, London, Ontario N6A 5B7, Canada
    Soc Cogn Affect Neurosci 9:628-37. 2014
    ....
  3. doi Conscious perception of emotional stimuli: brain mechanisms
    Derek G V Mitchell
    Department of Psychiatry and Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Neuroscientist 18:386-98. 2012
    ....
  4. pmc The interference of operant task performance by emotional distracters: an antagonistic relationship between the amygdala and frontoparietal cortices
    D G V Mitchell
    Department of Psychiatry and Department of Anatomy and Cell Biology, The University of Western Ontario, London, Canada
    Neuroimage 40:859-68. 2008
    ....
  5. pmc The impact of processing load on emotion
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Neuroimage 34:1299-309. 2007
    ..Together, the data suggest that the processing of task-irrelevant emotional information, like neutral information, is subject to the effects of processing load and is under top-down control...
  6. pmc Adapting to dynamic stimulus-response values: differential contributions of inferior frontal, dorsomedial, and dorsolateral regions of prefrontal cortex to decision making
    Derek G V Mitchell
    National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Neurosci 29:10827-34. 2009
    ..These data are interpreted with reference to models of dmPFC, dlPFC, and IFG functioning...
  7. doi The nexus between decision making and emotion regulation: a review of convergent neurocognitive substrates
    Derek G V Mitchell
    Department of Psychiatry and Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, The University of Western Ontario, Canada
    Behav Brain Res 217:215-31. 2011
    ..Emphasis is placed on dorsomedial, dorsolateral, ventrolateral, and ventromedial regions of prefrontal cortex...
  8. pmc The contribution of ventrolateral and dorsolateral prefrontal cortex to response reversal
    D G V Mitchell
    Department of Psychiatry, The University of Western Ontario, London, Canada
    Behav Brain Res 187:80-7. 2008
    ..These data also suggest that dorsolateral prefrontal cortex plays a role in reversal learning, probably through top down attentional control of object or reinforcement features when task demands increase...
  9. ncbi Emotion-related brain activity to conflicting socio-emotional cues in unmedicated depression
    Steven G Greening
    Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, London, Ontario, Canada
    J Affect Disord 150:1136-41. 2013
    ..We sought to determine how the task relevance of socio-emotional cues impacts neural encoding of emotion in depression...
  10. doi Reduced amygdala response to fearful expressions in children and adolescents with callous-unemotional traits and disruptive behavior disorders
    Abigail A Marsh
    Mood and Anxiety Program, NIMH, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
    Am J Psychiatry 165:712-20. 2008
    ..Moreover, despite high comorbidity of callous-unemotional traits and attention deficit hyperactivity disorder (ADHD), no research has attempted to distinguish neural correlates of pediatric callous-unemotional traits and ADHD...
  11. pmc Do fearful eyes activate empathy-related brain regions in individuals with callous traits?
    Thida Han
    Program in Neuroscience, The University of Western Ontario, London, Ontario, Canada
    Soc Cogn Affect Neurosci 7:958-68. 2012
    ....
  12. doi The amygdala encodes level of perceived fear but not emotional ambiguity in visual scenes
    James H Kryklywy
    Department of Psychiatry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A 5A5, Canada
    Behav Brain Res 252:396-404. 2013
    ....
  13. doi Parsing decision making processes in prefrontal cortex: response inhibition, overcoming learned avoidance, and reversal learning
    Steven G Greening
    Department of Anatomy and Cell Biology, The University of Western Ontario, London, Ontario, Canada
    Neuroimage 54:1432-41. 2011
    ..The approach has implications for models of prefrontal function and neurocognitive perspectives on a range of behavioural abnormalities associated with impairments in decision making...
  14. pmc Dissociable roles of medial orbitofrontal cortex in human operant extinction learning
    Elizabeth C Finger
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Neuroimage 43:748-55. 2008
    ..These findings suggest that in humans, frontopolar OFC modulates activity in caudal mOFC, rACC and amygdala during successful operant extinction learning...
  15. doi The effects of oxytocin on social cognition and behaviour in frontotemporal dementia
    Sarah Jesso
    Department of Clinical Neurological Sciences, University of Western Ontario, B10 004, 339 Windermere Rd, London, ON, Canada N6A 5A5
    Brain 134:2493-501. 2011
    ....
  16. pmc Modulation of emotion by cognition and cognition by emotion
    K S Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 2670, USA
    Neuroimage 35:430-40. 2007
    ..NeuroImage, 29 (3), 721-733] and negative connectivity with bilateral amygdala. These data suggest that processes involved in emotional regulation are recruited during task performance in the context of emotional distractors...
  17. ncbi Emotion modulates activity in the 'what' but not 'where' auditory processing pathway
    James H Kryklywy
    Graduate Program in Neuroscience, University of Western Ontario, London, Ontario N6A 5A5, Canada
    Neuroimage 82:295-305. 2013
    ..These results suggest that emotion modulates activity in the 'what,' but not the 'where,' auditory processing pathway. ..
  18. ncbi Emotion at the expense of cognition: psychopathic individuals outperform controls on an operant response task
    Derek G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892, USA
    J Abnorm Psychol 115:559-66. 2006
    ..Results are discussed with reference to current models regarding the modulation of attention by emotion and the emotional impairment seen in individuals with psychopathy...
  19. ncbi Caught in the act: the impact of audience on the neural response to morally and socially inappropriate behavior
    Elizabeth C Finger
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 15K, North Drive, MSC 2670, Bethesda, MD 20892, USA
    Neuroimage 33:414-21. 2006
    ..These regions have been implicated in the representation of the mental states of others (Theory of Mind). The presence of an audience was associated with increased left amygdala activity across all conditions...
  20. ncbi Getting mixed messages: the impact of conflicting social signals on the brain's target emotional response
    Jayna M Amting
    Department of Psychiatry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada
    Neuroimage 47:1950-9. 2009
    ..The results are interpreted with reference to current models of emotional attention and regulation...
  21. ncbi Divergent patterns of aggressive and neurocognitive characteristics in acquired versus developmental psychopathy
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Neurocase 12:164-78. 2006
    ....
  22. ncbi The development of psychopathy
    R J R Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Heath, Department of Health and Human Services, Bethesda, MD, USA
    J Child Psychol Psychiatry 47:262-76. 2006
    ..These impairments disrupt the impact of standard socialization techniques and increase the risk for frustration-induced reactive aggression respectively...
  23. ncbi Is the emotion recognition deficit associated with frontotemporal dementia caused by selective inattention to diagnostic facial features?
    Lindsay D Oliver
    Graduate Program in Neuroscience, University of Western Ontario, London, ON, Canada Department of Psychology, Brain and Mind Institute, University of Western Ontario, London, ON, Canada
    Neuropsychologia 60:84-92. 2014
    ..This work suggests that the emotional expression recognition deficit associated with FTD is unlikely to be rectified by adjusting selective attention to diagnostic features, as has proven useful in other select disorders. ..
  24. ncbi Instrumental learning and relearning in individuals with psychopathy and in patients with lesions involving the amygdala or orbitofrontal cortex
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
    Neuropsychology 20:280-9. 2006
    ..The results are interpreted with reference to current neurocognitive models of stimulus-reinforcement learning, relearning, and developmental psychopathy...
  25. pmc Psychopathy, attention and emotion
    R J R Blair
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Psychol Med 39:543-55. 2009
    ....
  26. ncbi They know the words, but not the music: affective and semantic priming in individuals with psychopathy
    K S Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Biol Psychol 73:114-23. 2006
    ..In contrast, the two groups showed comparable levels of semantic priming. The results are discussed with reference to current models of psychopathy...
  27. ncbi Differentiating among prefrontal substrates in psychopathy: neuropsychological test findings
    K S Blair
    National Institute of Mental Health and University College, London, UK
    Neuropsychology 20:153-65. 2006
    ..In contrast, the 2 groups did not show impairment on the measures preferentially sensitive to the functioning of the DLPFC or ACC. These results are interpreted with reference to executive dysfunction accounts of the disorder...
  28. ncbi Theory of mind and psychopathy: can psychopathic individuals read the 'language of the eyes'?
    R A Richell
    Institute of Cognitive Neuroscience, Department of Psychology, University College, London, UK
    Neuropsychologia 41:523-6. 2003
    ..Results indicated that the psychopathic individuals did not present with any generalised impairment in ToM. The data are discussed with reference to the putative neural system mediating performance on this task and models of psychopathy...
  29. ncbi Risky decisions and response reversal: is there evidence of orbitofrontal cortex dysfunction in psychopathic individuals?
    D G V Mitchell
    Institute of Cognitive Neuroscience, University College London, UK
    Neuropsychologia 40:2013-22. 2002
    ..These results are interpreted with reference to an OFC and amygdala dysfunction explanation of psychopathy...