Lisa M Mielniczuk

Summary

Affiliation: University of Ottawa Heart Institute
Country: Canada

Publications

  1. doi request reprint Riociguat: a novel therapeutic option for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
    Lisa M Mielniczuk
    Department of Medicine, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Onatrio, Canada Electronic address
    Can J Cardiol 30:1233-40. 2014
  2. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
  3. pmc Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
    Benjamin J W Chow
    Department of Medicine, Division of Cardiology, including Cardiac Imaging, The Heart Failure Program, and the Cardiac ResearchMethods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Trials 14:443. 2013
  4. pmc Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal, QC, Canada
    Trials 14:218. 2013
  5. doi request reprint Worsening renal function and prognosis in pulmonary hypertension patients hospitalized for right heart failure
    Lisa M Mielniczuk
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada
    Congest Heart Fail 18:151-7. 2012
  6. doi request reprint Relation between right ventricular function and increased right ventricular [18F]fluorodeoxyglucose accumulation in patients with heart failure
    Lisa M Mielniczuk
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    Circ Cardiovasc Imaging 4:59-66. 2011
  7. doi request reprint Ultrafiltration in the management of acute decompensated heart failure
    Lisa M Mielniczuk
    University of Ottawa Heart Institute, Ontario, Canada
    Curr Opin Cardiol 25:155-60. 2010
  8. pmc Acute decline in renal function, inflammation, and cardiovascular risk after an acute coronary syndrome
    Lisa M Mielniczuk
    University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada
    Clin J Am Soc Nephrol 4:1811-7. 2009
  9. doi request reprint Estimated glomerular filtration rate, inflammation, and cardiovascular events after an acute coronary syndrome
    Lisa M Mielniczuk
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am Heart J 155:725-31. 2008
  10. ncbi request reprint Left ventricular end-diastolic pressure and risk of subsequent heart failure in patients following an acute myocardial infarction
    Lisa M Mielniczuk
    Cardiology Division, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Congest Heart Fail 13:209-14. 2007

Detail Information

Publications18

  1. doi request reprint Riociguat: a novel therapeutic option for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
    Lisa M Mielniczuk
    Department of Medicine, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Onatrio, Canada Electronic address
    Can J Cardiol 30:1233-40. 2014
    ..This article reviews the key findings from the phase III trials for riociguat that led to these approvals and the implications this has for the treatment of patients with PAH and CTEPH. ..
  2. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
    ..This will lead to a reduction in the non-specific diagnoses of idiopathic dilated cardiomyopathy and HF with preserved ejection fraction...
  3. pmc Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
    Benjamin J W Chow
    Department of Medicine, Division of Cardiology, including Cardiac Imaging, The Heart Failure Program, and the Cardiac ResearchMethods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Trials 14:443. 2013
    ..Acknowledging the aging population, the growing prevalence of HF and the increasing financial burden of healthcare, we need to identify non-invasive diagnostic tests that are available, safe, accurate and cost-effective...
  4. pmc Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal, QC, Canada
    Trials 14:218. 2013
    ....
  5. doi request reprint Worsening renal function and prognosis in pulmonary hypertension patients hospitalized for right heart failure
    Lisa M Mielniczuk
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada
    Congest Heart Fail 18:151-7. 2012
    ..89). Significant renal dysfunction is common in patients with PH and an acute decline in renal function is an important marker of in hospital death and short term mortality in right heart failure...
  6. doi request reprint Relation between right ventricular function and increased right ventricular [18F]fluorodeoxyglucose accumulation in patients with heart failure
    Lisa M Mielniczuk
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    Circ Cardiovasc Imaging 4:59-66. 2011
    ....
  7. doi request reprint Ultrafiltration in the management of acute decompensated heart failure
    Lisa M Mielniczuk
    University of Ottawa Heart Institute, Ontario, Canada
    Curr Opin Cardiol 25:155-60. 2010
    ..One alternative to standard therapy is mechanical fluid removal with ultrafiltration, this review will highlight the current evidence and efficacy regarding ultrafiltration use in acute heart failure...
  8. pmc Acute decline in renal function, inflammation, and cardiovascular risk after an acute coronary syndrome
    Lisa M Mielniczuk
    University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada
    Clin J Am Soc Nephrol 4:1811-7. 2009
    ..The prognostic significance of worsening renal function has also been shown in various cohorts of cardiac disease; however, the predictors of worsening renal function and the contribution of inflammation remains to be established...
  9. doi request reprint Estimated glomerular filtration rate, inflammation, and cardiovascular events after an acute coronary syndrome
    Lisa M Mielniczuk
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am Heart J 155:725-31. 2008
    ..However, it remains to be established whether the prognostic value of impaired estimated glomerular filtration rate (GFR) remains after accounting for markers of inflammation...
  10. ncbi request reprint Left ventricular end-diastolic pressure and risk of subsequent heart failure in patients following an acute myocardial infarction
    Lisa M Mielniczuk
    Cardiology Division, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Congest Heart Fail 13:209-14. 2007
    ..77-1.65). Elevated LVEDP is common following myocardial infarction; however, it is not an independent predictor of subsequent HF risk. The variability in LVEDP is not fully explained by infarct size and atherosclerotic burden...
  11. doi request reprint Usefulness of beta-blocker therapy and outcomes in patients with pulmonary arterial hypertension
    Petsy Pui Sze So
    University of Ottawa Heart Institute, Ontario, Canada
    Am J Cardiol 109:1504-9. 2012
    ..Further randomized data are needed to evaluate the potential benefits and risks of β-blocker use in patients with PAH...
  12. doi request reprint Effects of short-term continuous positive airway pressure on myocardial sympathetic nerve function and energetics in patients with heart failure and obstructive sleep apnea: a randomized study
    Allison B Hall
    From the National Cardiac PET Center, Division of Cardiology, Department of Medicine A B H, M C Z, S C, I G B, J R, R A D, H H, L M M, K Y, A G, O W, L G, J N D, R S B B, and Cardiac Research Methods Center L C, University of Ottawa Heart Institute, Ottawa, Canada Diagnostico Medico Oronia, Non Invasive Cardiovascular Imaging Department, Rosario, Santa Fe, Argentina M C Z Division of Respirology, Department of Medicine, Ottawa Hospital, University of Ottawa, Ottawa, Canada J A L Department of Molecular Imaging, Hokkaido University Graduate School of Medicince, Sapporo, Japan K Y and Division of Cardiology, Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Canada J S F
    Circulation 130:892-901. 2014
    ..We hypothesized that short-term (6-8 weeks) CPAP in patients with OSA and heart failure with reduced ejection fraction would improve myocardial sympathetic nerve function and energetics...
  13. doi request reprint Giant cell myocarditis in a patient with a spondyloarthropathy after a drug hypersensitivity reaction
    Peter R Mitoff
    Divisions of Cardiology, Cardiac Surgery and Nursing, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Can J Cardiol 29:1138.e7-8. 2013
    ..Heart failure symptoms returned and she eventually required a heart transplant; the explanted heart showed giant cell myocarditis. ..
  14. doi request reprint Prognostic value of rubidium-82 positron emission tomography in patients after heart transplant
    Brian A Mc Ardle
    From the Division of Cardiology, Department of Medicine B A M A, R A D, G R S, T D R, G D, Y Y, H H, L M M, E S, R H, R S B, B J W C, National Cardiac PET Center B A M A, R A D, T D R, R H, A G, R S B, R A D, B J W C, and Division of Cardiology, Department of Medicine, Cardiovascular Research Methods Center L C, University of Ottawa Heart Institute Ottawa, Canada
    Circ Cardiovasc Imaging 7:930-7. 2014
    ..Positron emission tomography using rubidium-82 allows quantification of absolute myocardial blood flow and may have utility for risk stratification in this population...
  15. doi request reprint Imaging the failing right ventricle
    Peter R Mitoff
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Curr Opin Cardiol 27:148-53. 2012
    ....
  16. doi request reprint The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients
    Lisa M Mielniczuk
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Card Fail 14:388-93. 2008
    ..In chronic heart failure (HF), diuretic doses increase as the disease progresses, often after hospitalization for instability, and have been associated with worsening renal function and increased mortality...
  17. ncbi request reprint Immune modulation therapy in heart failure
    Lisa M Mielniczuk
    Department of Medicine, Division of Cardiovascular Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Congest Heart Fail 12:91-6; quiz 97-8. 2006
    ....
  18. ncbi request reprint Evaluation and monitoring of patients with acute heart failure syndromes
    Anju Nohria
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Cardiol 96:32G-40G. 2005
    ..Development of validated and reproducible noninvasive techniques to monitor patients with acute HF will be an important step in maximizing interventions to improve outcomes in this patient population...