Kelly A Meckling

Summary

Affiliation: University of Guelph
Country: Canada

Publications

  1. ncbi request reprint Effects of a hypocaloric, low-carbohydrate diet on weight loss, blood lipids, blood pressure, glucose tolerance, and body composition in free-living overweight women
    Kelly A Meckling
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON NIG 2W1, Canada
    Can J Physiol Pharmacol 80:1095-105. 2002
  2. pmc Fatty acid status and behavioural symptoms of attention deficit hyperactivity disorder in adolescents: a case-control study
    Ashley L Colter
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada
    Nutr J 7:8. 2008
  3. ncbi request reprint A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women
    Kelly A Meckling
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada
    Appl Physiol Nutr Metab 32:743-52. 2007
  4. doi request reprint In vitro antioxidant synergism and antagonism between food extracts can lead to similar activities in H2O2-induced cell death, caspase-3 and MMP-2 activities in H9c2 cells
    Sunan Wang
    Guelph Food Research Center, Agriculture and Agri Food Canada, Guelph, Ontario, Canada
    J Sci Food Agric 92:2983-93. 2012
  5. doi request reprint Effect of the protein:carbohydrate ratio in hypoenergetic diets on metabolic syndrome risk factors in exercising overweight and obese women
    Dawn D Campbell
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Br J Nutr 108:1658-71. 2012
  6. ncbi request reprint Comparison of a low-fat diet to a low-carbohydrate diet on weight loss, body composition, and risk factors for diabetes and cardiovascular disease in free-living, overweight men and women
    Kelly A Meckling
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, N1G 2W1 Ontario, Canada
    J Clin Endocrinol Metab 89:2717-23. 2004
  7. doi request reprint Nuclear translocation of the 1,25D3-MARRS (membrane associated rapid response to steroids) receptor protein and NFkappaB in differentiating NB4 leukemia cells
    Wenqing Wu
    Department of Human Health, University of Guelph, Guelph, Ontario, Canada
    Exp Cell Res 316:1101-8. 2010
  8. ncbi request reprint Guanosine acts intracellularly to initiate apoptosis in NB4 cells: A role for nucleoside transport
    Sheryl A Flanagan
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Leuk Lymphoma 48:1816-27. 2007
  9. doi request reprint Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells
    Cynthia L Richard
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G2W1
    Exp Cell Res 316:695-703. 2010
  10. ncbi request reprint Nucleoside transporter expression and activity is regulated during granulocytic differentiation of NB4 cells in response to all-trans-retinoic acid
    Sheryl A Flanagan
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Leuk Res 31:955-68. 2007

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Effects of a hypocaloric, low-carbohydrate diet on weight loss, blood lipids, blood pressure, glucose tolerance, and body composition in free-living overweight women
    Kelly A Meckling
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON NIG 2W1, Canada
    Can J Physiol Pharmacol 80:1095-105. 2002
    ....
  2. pmc Fatty acid status and behavioural symptoms of attention deficit hyperactivity disorder in adolescents: a case-control study
    Ashley L Colter
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada
    Nutr J 7:8. 2008
    ..A secondary purpose was to determine if there were relationships between circulating concentrations of essential fatty acids and specific ADHD behaviours as measured by the Conners' Parent Rating Scale (CPRS-L)...
  3. ncbi request reprint A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women
    Kelly A Meckling
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada
    Appl Physiol Nutr Metab 32:743-52. 2007
    ....
  4. doi request reprint In vitro antioxidant synergism and antagonism between food extracts can lead to similar activities in H2O2-induced cell death, caspase-3 and MMP-2 activities in H9c2 cells
    Sunan Wang
    Guelph Food Research Center, Agriculture and Agri Food Canada, Guelph, Ontario, Canada
    J Sci Food Agric 92:2983-93. 2012
    ..This in vitro study evaluated the relationship between the in vitro antioxidant capacity of mixtures and their bioactivity when cardiomyocytes (H9c2) were challenged with H(2)O(2)...
  5. doi request reprint Effect of the protein:carbohydrate ratio in hypoenergetic diets on metabolic syndrome risk factors in exercising overweight and obese women
    Dawn D Campbell
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Br J Nutr 108:1658-71. 2012
    ..A diet with a 1:2 protein:carbohydrate ratio promoted better improvements than either the LP or HP diets, and may be superior in reducing long-term chronic disease risk in this population...
  6. ncbi request reprint Comparison of a low-fat diet to a low-carbohydrate diet on weight loss, body composition, and risk factors for diabetes and cardiovascular disease in free-living, overweight men and women
    Kelly A Meckling
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, N1G 2W1 Ontario, Canada
    J Clin Endocrinol Metab 89:2717-23. 2004
    ..These data suggest that energy restriction achieved by a very LC diet is equally effective as a LF diet strategy for weight loss and decreasing body fat in overweight and obese adults...
  7. doi request reprint Nuclear translocation of the 1,25D3-MARRS (membrane associated rapid response to steroids) receptor protein and NFkappaB in differentiating NB4 leukemia cells
    Wenqing Wu
    Department of Human Health, University of Guelph, Guelph, Ontario, Canada
    Exp Cell Res 316:1101-8. 2010
    ..This suggests a role for 1,25D(3)-MARRS in the nucleus as a regulator of gene expression. Here it may also regulate the activity of NFkappaB and other factors with which it may be interacting...
  8. ncbi request reprint Guanosine acts intracellularly to initiate apoptosis in NB4 cells: A role for nucleoside transport
    Sheryl A Flanagan
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    Leuk Lymphoma 48:1816-27. 2007
    ..Expression of the unique guanosine-specific nucleoside transporter csg in NB4 cells may provide an opportunity to harness guanosine-mediated cell death in the treatment of APL and related malignancies while sparing normal cells...
  9. doi request reprint Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells
    Cynthia L Richard
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G2W1
    Exp Cell Res 316:695-703. 2010
    ..Further research should examine the potential for pharmacological or natural agents that modify 1,25D3-MARRS expression or activity as anticancer agents...
  10. ncbi request reprint Nucleoside transporter expression and activity is regulated during granulocytic differentiation of NB4 cells in response to all-trans-retinoic acid
    Sheryl A Flanagan
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Leuk Res 31:955-68. 2007
    ....
  11. ncbi request reprint Dietary docosahexaenoic acid levels influence the outcome of arabinosylcytosine chemotherapy in L1210 leukemic mice
    Ming C Cha
    Department of Human Biology and Nutrition Sciences, University of Guelph, Guelph, ON, Canada N1G 2W1
    Nutr Cancer 44:176-81. 2002
    ..These data suggest that a modest level of dietary DHA or linoleic acid supplementation may improve the antineoplastic efficacy of AraC. However, overconsumption of DHA reverses the beneficial effect of DHA intake on drug sensitivity...
  12. pmc Vitamin status and cognitive function in a long-term care population
    Lina Paulionis
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
    BMC Geriatr 5:16. 2005
    ....
  13. pmc Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
    Ming C Cha
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    BMC Pharmacol 5:7. 2005
    ..Here we investigate whether the omega-3 fatty acid docosahexaenoic acid (DHA) could selectively target araC toxicity toward colonic tumor cells while protecting the normal cells in vitro...
  14. doi request reprint Synergistic, additive, and antagonistic effects of food mixtures on total antioxidant capacities
    Sunan Wang
    Guelph Food Research Center, Agriculture and Agri Food Canada, Guelph, Ontario, Canada
    J Agric Food Chem 59:960-8. 2011
    ..Compositional changes did not seem to have occurred in the mixture. Results in this study suggest the importance of strategically selecting foods or diets to maximum synergisms as well as to minimum antagonisms in antioxidant activity...
  15. ncbi request reprint Fatty acids and exercise affect glucose transport but not tumour growth in F-344 rats
    Jennifer M Foley
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON
    Can J Appl Physiol 29:604-22. 2004
    ..High DHA diets may also increase oxidative damage in muscle through enhanced TBARM production...
  16. ncbi request reprint 1alpha,25-dihydroxyvitamin D3 and bryostatin-1 synergize to induce monocytic differentiation of NB4 acute promyelocytic leukemia cells by modulating cell cycle progression
    Christina S Clark
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Exp Cell Res 294:301-11. 2004
    ..Levels of the cyclin-dependent kinase inhibitors p21 and p27 as well as Cyclin D1 were undetectable in NB4 cell lysates, suggesting that they do not participate in the differentiation response or cell cycle control in this model...
  17. ncbi request reprint The novel nucleoside transport system exhibited by NB4 cells, csg, transports deoxyguanosine analogues, including ara-G
    Sheryl A Flanagan
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ont, Canada N1G 2W1
    Biochem Pharmacol 66:733-7. 2003
    ..Competition assays revealed that this analogue potentiated the inward flux of guanosine and was capable of killing NB4 cells with potency similar to the conventional leukemia drug, ara-C...