Burkhard Mädler

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. doi request reprint Is diffusion anisotropy an accurate monitor of myelination? Correlation of multicomponent T2 relaxation and diffusion tensor anisotropy in human brain
    Burkhard Mädler
    Department of Physics and Astronomy, University of British Columbia Hospital, Vancouver BC, Canada
    Magn Reson Imaging 26:874-88. 2008
  2. doi request reprint Myelin water imaging: Implementation and development at 3.0T and comparison to 1.5T measurements
    Shannon H Kolind
    Department of Physics and Astronomy, University of British Columbia, Vancouver, Canada
    Magn Reson Med 62:106-15. 2009
  3. doi request reprint Short-term stability of T1 and T2 relaxation measures in multiple sclerosis normal appearing white matter
    Alice L W Liang
    Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada
    J Neurol 259:1151-8. 2012
  4. ncbi request reprint Insights into brain microstructure from the T2 distribution
    Alex MacKay
    Department of Radiology, University of British Columbia, Vancouver, BC, Canada
    Magn Reson Imaging 24:515-25. 2006
  5. ncbi request reprint MR evidence of long T2 water in pathological white matter
    Cornelia Laule
    Department of Radiology, University of British Columbia, Vancouver, BC, Canada
    J Magn Reson Imaging 26:1117-21. 2007
  6. doi request reprint Myelin water and T(2) relaxation measurements in the healthy cervical spinal cord at 3.0T: repeatability and changes with age
    Erin L MacMillan
    Department of Physics and Astronomy, University of British Columbia, Vancouver, British Columbia, Canada
    Neuroimage 54:1083-90. 2011
  7. doi request reprint Applications of stimulated echo correction to multicomponent T2 analysis
    Thomas Prasloski
    Department of Physics and Astronomy, University of British Columbia, Vancouver, British Columbia, Canada
    Magn Reson Med 67:1803-14. 2012
  8. doi request reprint Complementary information from multi-exponential T2 relaxation and diffusion tensor imaging reveals differences between multiple sclerosis lesions
    Shannon H Kolind
    Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada
    Neuroimage 40:77-85. 2008

Collaborators

Detail Information

Publications8

  1. doi request reprint Is diffusion anisotropy an accurate monitor of myelination? Correlation of multicomponent T2 relaxation and diffusion tensor anisotropy in human brain
    Burkhard Mädler
    Department of Physics and Astronomy, University of British Columbia Hospital, Vancouver BC, Canada
    Magn Reson Imaging 26:874-88. 2008
    ..Conversely, in structures with disorganized fibre bundles and multiple fibre crossings, such as the minor and major forceps, low FA values were measured, which does not necessarily reflect a decrease myelin-water content...
  2. doi request reprint Myelin water imaging: Implementation and development at 3.0T and comparison to 1.5T measurements
    Shannon H Kolind
    Department of Physics and Astronomy, University of British Columbia, Vancouver, Canada
    Magn Reson Med 62:106-15. 2009
    ..5T, but with a strongly significant correlation between measurements (R(2) > 0.92, P < 0.0005). The signal-to-noise ratio (SNR) was nearly double at 3.0T, but the standard deviation of residuals was increased in most cases...
  3. doi request reprint Short-term stability of T1 and T2 relaxation measures in multiple sclerosis normal appearing white matter
    Alice L W Liang
    Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada
    J Neurol 259:1151-8. 2012
    ..We observed no change in MWF, GMT(2) or T(1) histogram metrics in NAWM in RRMS over the course of 6 months. Longer follow-up periods may be required to establish demonstrable changes in NAWM based on of MWF, GMT(2) and T(1) metrics...
  4. ncbi request reprint Insights into brain microstructure from the T2 distribution
    Alex MacKay
    Department of Radiology, University of British Columbia, Vancouver, BC, Canada
    Magn Reson Imaging 24:515-25. 2006
    ..A strong correlation between MWF and the optical density from the luxol fast blue histological stain for myelin was observed in formalin-fixed brain, supporting the use of the MWF as an in vivo myelin marker...
  5. ncbi request reprint MR evidence of long T2 water in pathological white matter
    Cornelia Laule
    Department of Radiology, University of British Columbia, Vancouver, BC, Canada
    J Magn Reson Imaging 26:1117-21. 2007
    ..To describe what, if any, specific long T(2)-related abnormalities occur in the white matter of subjects with either phenylketonuria (PKU) or multiple sclerosis (MS)...
  6. doi request reprint Myelin water and T(2) relaxation measurements in the healthy cervical spinal cord at 3.0T: repeatability and changes with age
    Erin L MacMillan
    Department of Physics and Astronomy, University of British Columbia, Vancouver, British Columbia, Canada
    Neuroimage 54:1083-90. 2011
    ....
  7. doi request reprint Applications of stimulated echo correction to multicomponent T2 analysis
    Thomas Prasloski
    Department of Physics and Astronomy, University of British Columbia, Vancouver, British Columbia, Canada
    Magn Reson Med 67:1803-14. 2012
    ..Most notably, myelin water fraction values in these regions are found to have increased consistency and accuracy...
  8. doi request reprint Complementary information from multi-exponential T2 relaxation and diffusion tensor imaging reveals differences between multiple sclerosis lesions
    Shannon H Kolind
    Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada
    Neuroimage 40:77-85. 2008
    ..02-0.04, p>0.07), and only weak correlations were found in lesions without long-T(2) signal (R(2)=0.05-0.14, p<0.04), strong correlations were observed in lesions exhibiting long-T(2) signal (R(2)=0.54-0.61, p<0.0001)...