Anthony Randal McIntosh

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Recruitment of unique neural systems to support visual memory in normal aging
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, Toronto, Ontario, Canada
    Curr Biol 9:1275-8. 1999
  2. ncbi request reprint Partial least squares analysis of neuroimaging data: applications and advances
    Anthony Randal McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada M6A 2E1
    Neuroimage 23:S250-63. 2004
  3. ncbi request reprint Functional connectivity of the medial temporal lobe relates to learning and awareness
    Anthony Randal McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario M6A 2E1, Canada
    J Neurosci 23:6520-8. 2003
  4. ncbi request reprint Interactions of prefrontal cortex in relation to awareness in sensory learning
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada
    Science 284:1531-3. 1999
  5. ncbi request reprint Spatiotemporal analysis of event-related fMRI data using partial least squares
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
    Neuroimage 23:764-75. 2004
  6. ncbi request reprint Convergence of neural systems processing stimulus associations and coordinating motor responses
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, Toronto, Ontario, Canada
    Cereb Cortex 8:648-59. 1998
  7. ncbi request reprint Towards a network theory of cognition
    A R McIntosh
    Rotman Research Institute, Baycrest Centre, Department of Psychology, University of Toronto, Ontario, Canada
    Neural Netw 13:861-70. 2000
  8. ncbi request reprint Contexts and catalysts: a resolution of the localization and integration of function in the brain
    Anthony Randal McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, 3560 Bathurst Street, Ontario M6A 2E1, Canada
    Neuroinformatics 2:175-82. 2004
  9. doi request reprint The co-occurrence of multisensory facilitation and cross-modal conflict in the human brain
    Andreea Oliviana Diaconescu
    Rotman Research Institute, Baycrest Centre, Toronto, Canada
    J Neurophysiol 106:2896-909. 2011
  10. doi request reprint Modality-independent processes in cued motor preparation revealed by cortical potentials
    Andreea Oliviana Diaconescu
    Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada
    Neuroimage 42:1255-65. 2008

Detail Information

Publications45

  1. ncbi request reprint Recruitment of unique neural systems to support visual memory in normal aging
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, Toronto, Ontario, Canada
    Curr Biol 9:1275-8. 1999
    ..These unique areas were strongly interactive and their activity was related to performance only in old participants. Therefore, these areas may have acted to compensate for reduced interactions between the other brain areas...
  2. ncbi request reprint Partial least squares analysis of neuroimaging data: applications and advances
    Anthony Randal McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada M6A 2E1
    Neuroimage 23:S250-63. 2004
    ..We further discuss its role as an important tool in a pluralistic analytic approach to neuroimaging...
  3. ncbi request reprint Functional connectivity of the medial temporal lobe relates to learning and awareness
    Anthony Randal McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario M6A 2E1, Canada
    J Neurosci 23:6520-8. 2003
    ..Thus, the contribution of the MTL to learning and awareness is shaped by the pattern of interregional interactions, the neural context...
  4. ncbi request reprint Interactions of prefrontal cortex in relation to awareness in sensory learning
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada
    Science 284:1531-3. 1999
    ..Several of the interacting areas correlated with aware subjects' behavior. These results suggest cerebral processes underlying awareness are mediated through interactions of large-scale neurocognitive systems...
  5. ncbi request reprint Spatiotemporal analysis of event-related fMRI data using partial least squares
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
    Neuroimage 23:764-75. 2004
    ..These features enable ST-PLS to act as an important complement to other multivariate and univariate approaches used in neuroimaging research...
  6. ncbi request reprint Convergence of neural systems processing stimulus associations and coordinating motor responses
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, Toronto, Ontario, Canada
    Cereb Cortex 8:648-59. 1998
    ....
  7. ncbi request reprint Towards a network theory of cognition
    A R McIntosh
    Rotman Research Institute, Baycrest Centre, Department of Psychology, University of Toronto, Ontario, Canada
    Neural Netw 13:861-70. 2000
    ..Instead, the neural context in which an area is active may define the cognitive function. Neural context emphasizes that the particular spatiotemporal pattern of neural interactions may hold the key to bridge between brain and mind...
  8. ncbi request reprint Contexts and catalysts: a resolution of the localization and integration of function in the brain
    Anthony Randal McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, 3560 Bathurst Street, Ontario M6A 2E1, Canada
    Neuroinformatics 2:175-82. 2004
    ..An imaging study on the changing interregional interactions involving the hippocampus in learning and awareness serves as an example of neural context. In this case, the hippocampus may serve to catalyze the transition to awareness...
  9. doi request reprint The co-occurrence of multisensory facilitation and cross-modal conflict in the human brain
    Andreea Oliviana Diaconescu
    Rotman Research Institute, Baycrest Centre, Toronto, Canada
    J Neurophysiol 106:2896-909. 2011
    ..However, as participants are required to evaluate cross-modal stimuli based on their semantic category or their degree of congruence, multisensory processes extend in cingulate, temporal, and prefrontal cortices...
  10. doi request reprint Modality-independent processes in cued motor preparation revealed by cortical potentials
    Andreea Oliviana Diaconescu
    Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada
    Neuroimage 42:1255-65. 2008
    ..The effects carried by both patterns showed temporal overlap in the interval between the first and second stimulus presentation, but with differences in their relation to response rule processing and behavioural facilitation...
  11. doi request reprint Neural system interactions underlying human transitive inference
    Sandra N Moses
    Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, Ontario, Canada
    Hippocampus 20:894-901. 2010
    ..Contrary to prior assumptions, the hippocampus and caudate interact cooperatively to facilitate successful TI. We suggest that the dynamics of the relationship between the hippocampus and caudate depends critically upon task demands...
  12. doi request reprint Modality-dependent "what" and "where" preparatory processes in auditory and visual systems
    Andreea Oliviana Diaconescu
    Rotman Research Institute, Baycrest Centre, Toronto, Ontario, Canada
    J Cogn Neurosci 23:1609-23. 2011
    ....
  13. ncbi request reprint Transperceptual encoding and retrieval processes in memory: a PET study of visual and haptic objects
    M Lepage
    Rotman Research Institute of Baycrest Centre, University of Toronto, 3560 Bathurst Street, Toronto, Ontario, M6A 2E1, Canada
    Neuroimage 14:572-84. 2001
    ..These results provide initial evidence that some processes involved in memory encoding and retrieval operate beyond perceptual processes and in that sense are transperceptual...
  14. doi request reprint The interplay of cue modality and response latency in brain areas supporting crossmodal motor preparation: an event-related fMRI study
    Zainab Fatima
    Rotman Research Institute, Baycrest Centre, 3560 Bathurst St, Toronto, ON M6A 2E1, Canada
    Exp Brain Res 214:9-17. 2011
    ..Our results show that both modality-dependent and modality-independent brain areas with different brain-behaviour relationships are implicated in crossmodal motor preparation...
  15. pmc Increased brain signal variability accompanies lower behavioral variability in development
    Anthony Randal McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada
    PLoS Comput Biol 4:e1000106. 2008
    ..Our results suggest that the moment-to-moment variability in brain activity may be a critical index of the cognitive capacity of the brain...
  16. doi request reprint Encoding the future: successful processing of intentions engages predictive brain networks
    J Poppenk
    Department of Psychology, University of Toronto, 100 St George Street, Toronto, Ontario, Canada
    Neuroimage 49:905-13. 2010
    ..It also provides the first evidence that PM encoding, like PM retrieval, is supported by both a common episodic memory network and an executive network specifically recruited by future-oriented processing...
  17. ncbi request reprint Neural correlates of semantic associative encoding in episodic memory
    M Lepage
    Rotman Research Institute of Baycrest Centre for Geriatric Care, 3560 Bathurst Street, University of Toronto, Toronto, ON, Canada
    Brain Res Cogn Brain Res 9:271-80. 2000
    ..These regions have been consistently reported in previous functional neuroimaging studies of associative encoding and may constitute key structures in association formation...
  18. ncbi request reprint Networks of domain-specific and general regions involved in episodic memory for spatial location and object identity
    S Kohler
    Rotman Research Institute of Baycrest Centre for Geriatric Care, University of Toronto, Ontario, Canada
    Neuropsychologia 36:129-42. 1998
    ....
  19. ncbi request reprint Limbic-frontal circuitry in major depression: a path modeling metanalysis
    D A Seminowicz
    Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
    Neuroimage 22:409-18. 2004
    ....
  20. doi request reprint Learning related activation of somatosensory cortex by an auditory stimulus recorded with magnetoencephalography
    Sandra N Moses
    Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, Canada
    Neuroimage 53:275-82. 2010
    ..This differentiation was largest between 150 and 350ms following US omission. We show that cross-modal CRs in the primary sensorimotor system are predominantly characterized by modulation of ongoing cortical oscillations...
  21. pmc Distinct functional networks associated with improvement of affective symptoms and cognitive function during citalopram treatment in geriatric depression
    Andreea Oliviana Diaconescu
    Rotman Research Institute, Baycrest Centre, Toronto, Ontario, Canada
    Hum Brain Mapp 32:1677-91. 2011
    ..Thus, alterations in specific brain networks associated with improvement of affective symptoms and cognitive function are observed during citalopram treatment in geriatric depression...
  22. ncbi request reprint The effects of aging on visual memory: evidence for functional reorganization of cortical networks
    P J Bennett
    Department of Psychology, University of Toronto, Suite 4020, 100 St. George St, Toronto, Ont. M5S 3G3, Canada
    Acta Psychol (Amst) 107:249-73. 2001
    ..However, the neural systems correlated with good performance differed for the two age groups. The results support the hypothesis that the functional networks that underlie visual memory undergo reorganization during aging...
  23. pmc Neural correlates of the episodic encoding of pictures and words
    C L Grady
    Rotman Research Institute of Baycrest Centre and Department of Psychology, University of Toronto, 3560 Bathurst Street, Toronto, Ontario, Canada, M6A 2E1
    Proc Natl Acad Sci U S A 95:2703-8. 1998
    ....
  24. pmc General and specific brain regions involved in encoding and retrieval of events: what, where, and when
    L Nyberg
    Rotman Research Institute of Baycrest Centre, University of Toronto, North York, ON, Canada
    Proc Natl Acad Sci U S A 93:11280-5. 1996
    ..These results point to the existence of general encoding and retrieval networks of episodic memory whose operations are augmented by unique brain areas recruited for processing specific aspects of remembered events...
  25. doi request reprint ICA-based artifact correction improves spatial localization of adaptive spatial filters in MEG
    Zainab Fatima
    Rotman Research Institute, Baycrest Centre, Toronto, Canada
    Neuroimage 78:284-94. 2013
    ....
  26. doi request reprint Dopamine-induced changes in neural network patterns supporting aversive conditioning
    Andreea Oliviana Diaconescu
    Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    Brain Res 1313:143-61. 2010
    ..These data provide insight into the distinct effects of DA agents on the functional connectivity between striatal, limbic, and prefrontal areas...
  27. ncbi request reprint Groupwise independent component decomposition of EEG data and partial least square analysis
    Natasa Kovacevic
    Rotman Research Institute Baycrest Centre 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
    Neuroimage 35:1103-12. 2007
    ..Comparative PLS analysis on the independent components versus original electrode data shows that task effects are not only preserved under compression, but also enhanced statistically...
  28. ncbi request reprint Frontotemporal interactions in face encoding and recognition
    M N Rajah
    Rotman Research Institute of Baycrest Centre, University of Toronto, 3560 Bathurst Street, Toronto, ON, Canada
    Brain Res Cogn Brain Res 8:259-69. 1999
    ..This pattern of interaction was specific to the recognition task and might represent the process whereby the input faces are compared to the internal representation laid down during encoding, thus enabling recognition...
  29. ncbi request reprint The effects of divided attention on encoding- and retrieval-related brain activity: A PET study of younger and older adults
    N D Anderson
    University of Toronto and Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    J Cogn Neurosci 12:775-92. 2000
    ....
  30. ncbi request reprint Individual differences in the functional neuroanatomy of verbal discrimination learning revealed by positron emission tomography
    R Habib
    Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, North York, Ont, Canada M6A 2E1
    Acta Psychol (Amst) 105:141-57. 2000
    ..These results suggest that individual differences in memory performance are related to differences in neural activity within specific brain circuits...
  31. ncbi request reprint Episodic memory and the self in a case of isolated retrograde amnesia
    B Levine
    Rotman Research Institute, Baycrest Centre for Geriatric Care, North York, Ontario, Canada
    Brain 121:1951-73. 1998
    ..Reorganized brain systems mediate certain preserved cognitive operations in M.L., but without the normal complement of information concerning the self with respect to both past and future events...
  32. ncbi request reprint Episodic encoding and recognition of pictures and words: role of the human medial temporal lobes
    S Kohler
    Rotman Research Institute of Baycrest Centre for Geriatric Care, University of Toronto, Toronto, Canada
    Acta Psychol (Amst) 105:159-79. 2000
    ..Together, our results provide evidence that the involvement of some but not all MTL regions in episodic encoding and recognition is format specific...
  33. ncbi request reprint Spatiotemporal analysis of experimental differences in event-related potential data with partial least squares
    N J Lobaugh
    Rotman Research Institute, Baycrest Centre for Geriatric Care and University of Toronto, Canada
    Psychophysiology 38:517-30. 2001
    ..PLS provides a mechanism to describe experimental differences in ERP waveforms, simultaneously across the head...
  34. pmc Functional reorganisation of memory after traumatic brain injury: a study with H(2)(15)0 positron emission tomography
    B Levine
    Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Canada
    J Neurol Neurosurg Psychiatry 73:173-81. 2002
    ..To study the effects of moderate to severe traumatic brain injury (TBI) on the functional neuroanatomy supporting memory retrieval...
  35. ncbi request reprint An examination of the effects of stimulus type, encoding task, and functional connectivity on the role of right prefrontal cortex in recognition memory
    C L Grady
    Rotman Research Institute, University of Toronto, Toronto, Ontario M6A 2E1, Canada
    Neuroimage 14:556-71. 2001
    ....
  36. ncbi request reprint Corticolimbic interactions associated with performance on a short-term memory task are modified by age
    V Della-Maggiore
    Rotman Research Institute of Baycrest Centre, Toronto, Ontario M6A 2E1, Canada
    J Neurosci 20:8410-6. 2000
    ..Recruitment of a distinct corticolimbic network for visual memory in the elderly suggests that age-related neurobiological deterioration not only results in focal changes but also in the modification of large-scale network operations...
  37. ncbi request reprint Quantifying head motion associated with motor tasks used in fMRI
    E Seto
    Imaging/Bioengineering Research, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario, M4N 3M5, Canada
    Neuroimage 14:284-97. 2001
    ..These results lead to several recommendations on the design of fMRI motor experiments and suggest that improved motion correction strategies are required to examine such patient populations comprehensively...
  38. ncbi request reprint Understanding neural interactions in learning and memory using functional neuroimaging
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, Toronto, Ontario, Canada
    Ann N Y Acad Sci 855:556-71. 1998
    ....
  39. ncbi request reprint Mapping cognition to the brain through neural interactions
    A R McIntosh
    University of Toronto, Canada
    Memory 7:523-48. 1999
    ....
  40. doi request reprint Tracing the route to path analysis in neuroimaging
    Anthony Randal McIntosh
    Rotman Research Institute at Baycrest Center, Department of Psychology, University of Toronto, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
    Neuroimage 62:887-90. 2012
    ..A method is useful when it provides insights that were previously inaccessible, and reflecting this, the paper concludes with a synopsis of the theoretical developments that arose for the routine use of methods like path analysis...
  41. pmc Semantic information alters neural activation during transverse patterning performance
    Sandra N Moses
    Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, Ontario, Canada
    Neuroimage 46:863-73. 2009
    ..These activation patterns may represent a shift towards reliance upon existing semantic knowledge. This shift likely permits successful TP performance with meaningful stimuli and relations following hippocampal damage...
  42. doi request reprint Why is the meaning of a sentence better remembered than its form? An fMRI study on the role of novelty-encoding processes
    J Poppenk
    Department of Psychology, University of Western Ontario, London, Ontario, Canada
    Hippocampus 18:909-18. 2008
    ..Our findings suggest that the verbatim effect can be linked to hippocampally-based novelty-assessment processes that operate based on semantic relationships...
  43. ncbi request reprint Multi-modality imaging data analysis with partial least squares
    W Chau
    Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Ont, Canada
    Brain Cogn 54:140-2. 2004
  44. ncbi request reprint On the marriage of cognition and neuroscience
    A R McIntosh
    Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario M6A 2E1, Canada
    Neuroimage 14:1231-7. 2001
    ..The imprecision of explanations for cognitive neuroscience data was also seen as a significant problem, suggesting that more principled attempts at explicit model specifications and prediction will be necessary for the field to develop...
  45. ncbi request reprint PET activation studies comparing two speech tasks widely used in surgical mapping
    Diana Vanlancker-Sidtis
    Department of Neurology, University of Southern California, Los Angeles, CA, USA
    Brain Lang 85:245-61. 2003
    ..Further studies are suggested to better understand differences between neurological substrates for non-propositional and automatic speech...