Mary Pat McAndrews

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Understanding medial temporal activation in memory tasks: evidence from fMRI of encoding and recognition in a case of transient global amnesia
    Robyn Westmacott
    Toronto Western Research Institute, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Hippocampus 18:317-25. 2008
  2. ncbi request reprint Cognitive effects of long-term benzodiazepine use in older adults
    Mary Pat McAndrews
    Department of Psychology, Toronto Western Hospital and University of Toronto, Canada
    Hum Psychopharmacol 18:51-7. 2003
  3. ncbi request reprint Prevalence and significance of neurocognitive dysfunction in hepatitis C in the absence of correlated risk factors
    Mary Pat McAndrews
    Divisions of Psychology, University Health Network, Toronto, Ontario, Canada
    Hepatology 41:801-8. 2005
  4. doi request reprint Self-reported depressive symptoms and memory complaints in survivors five years after ARDS
    Neill K J Adhikari
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada
    Chest 140:1484-93. 2011
  5. doi request reprint A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease
    Adrian W Laxton
    Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada
    Ann Neurol 68:521-34. 2010
  6. doi request reprint Default mode network connectivity indicates episodic memory capacity in mesial temporal lobe epilepsy
    Cornelia McCormick
    Krembil Neuroscience Center and Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Epilepsia 54:809-18. 2013
  7. doi request reprint Visuospatial associative memory and hippocampal functioning in congenital hypothyroidism
    Sarah M Wheeler
    Neuroscience and Mental Health Research Program, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    J Int Neuropsychol Soc 18:49-56. 2012
  8. doi request reprint Network interactions explain effective encoding in the context of medial temporal damage in MCI
    Andrea B Protzner
    Krembil Neuroscience Centre, University Health Network, Toronto, Ontario, Canada
    Hum Brain Mapp 32:1277-89. 2011
  9. ncbi request reprint Consequences of hippocampal damage across the autobiographical memory network in left temporal lobe epilepsy
    Donna Rose Addis
    Toronto Western Research Institute, Toronto, ON, Canada
    Brain 130:2327-42. 2007
  10. pmc Functional neuroanatomy of remote episodic, semantic and spatial memory: a unified account based on multiple trace theory
    Morris Moscovitch
    Department of Psychology, University of Toronto and Rotman Research Institute Baycrest Centre, Ontario, Canada
    J Anat 207:35-66. 2005

Detail Information

Publications37

  1. ncbi request reprint Understanding medial temporal activation in memory tasks: evidence from fMRI of encoding and recognition in a case of transient global amnesia
    Robyn Westmacott
    Toronto Western Research Institute, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Hippocampus 18:317-25. 2008
    ..Furthermore, the strong hippocampal activation during unsuccessful retrieval highlights important issues in interpreting memory-related activations, particularly in dysfunctional systems...
  2. ncbi request reprint Cognitive effects of long-term benzodiazepine use in older adults
    Mary Pat McAndrews
    Department of Psychology, Toronto Western Hospital and University of Toronto, Canada
    Hum Psychopharmacol 18:51-7. 2003
    ..However, the magnitude of these effects is quite small and may be of little clinical significance in the healthy elderly...
  3. ncbi request reprint Prevalence and significance of neurocognitive dysfunction in hepatitis C in the absence of correlated risk factors
    Mary Pat McAndrews
    Divisions of Psychology, University Health Network, Toronto, Ontario, Canada
    Hepatology 41:801-8. 2005
    ....
  4. doi request reprint Self-reported depressive symptoms and memory complaints in survivors five years after ARDS
    Neill K J Adhikari
    Interdepartmental Division of Critical Care, University of Toronto, Toronto, ON, Canada
    Chest 140:1484-93. 2011
    ..Survivors of ARDS report depressive symptoms and memory complaints, the prevalence of which after 5 years is unknown...
  5. doi request reprint A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease
    Adrian W Laxton
    Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada
    Ann Neurol 68:521-34. 2010
    ..We hypothesized that fornix/hypothalamus deep brain stimulation (DBS) could modulate neurophysiological activity in these pathological circuits and possibly produce clinical benefits...
  6. doi request reprint Default mode network connectivity indicates episodic memory capacity in mesial temporal lobe epilepsy
    Cornelia McCormick
    Krembil Neuroscience Center and Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    Epilepsia 54:809-18. 2013
    ....
  7. doi request reprint Visuospatial associative memory and hippocampal functioning in congenital hypothyroidism
    Sarah M Wheeler
    Neuroscience and Mental Health Research Program, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    J Int Neuropsychol Soc 18:49-56. 2012
    ..These results suggest that perinatal deprivation of thyroid hormone has longstanding effects on hippocampal function and may account for memory problems experienced by adolescents with congenital hypothyroidism...
  8. doi request reprint Network interactions explain effective encoding in the context of medial temporal damage in MCI
    Andrea B Protzner
    Krembil Neuroscience Centre, University Health Network, Toronto, Ontario, Canada
    Hum Brain Mapp 32:1277-89. 2011
    ..Our findings suggest that understanding brain-behavior relationships in neurological disorders requires examination of large-scale networks, even when dysfunction is relatively focal as in MCI...
  9. ncbi request reprint Consequences of hippocampal damage across the autobiographical memory network in left temporal lobe epilepsy
    Donna Rose Addis
    Toronto Western Research Institute, Toronto, ON, Canada
    Brain 130:2327-42. 2007
    ....
  10. pmc Functional neuroanatomy of remote episodic, semantic and spatial memory: a unified account based on multiple trace theory
    Morris Moscovitch
    Department of Psychology, University of Toronto and Rotman Research Institute Baycrest Centre, Ontario, Canada
    J Anat 207:35-66. 2005
    ....
  11. doi request reprint Influence of hepatitis C virus on neurocognitive function in patients free from other risk factors: validation from therapeutic outcomes
    Venessa Pattullo
    Department of Medicine, University Health Network, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
    Liver Int 31:1028-38. 2011
    ..This longitudinal study aimed to quantify these abnormalities in a cohort of patients free from correlated risk factors and determine whether treatment-induced viral clearance abolished these abnormalities...
  12. doi request reprint Memory enhancement induced by hypothalamic/fornix deep brain stimulation
    Clement Hamani
    Division of Neurosurgery, Toronto Western Hospital and Research Institute, University of Toronto, Toronto, Ontario, Canada
    Ann Neurol 63:119-23. 2008
    ..This shows that hypothalamic stimulation in this patient modulates limbic activity and improves certain memory functions...
  13. ncbi request reprint fMRI differences in encoding and retrieval of pictures due to encoding strategy in the elderly
    Jennifer L Mandzia
    Cognitive Neurology Unit and Imaging Research, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Hum Brain Mapp 21:1-14. 2004
    ..Focusing on the medial temporal lobe (MTL) region, our results suggest a greater involvement of both anterior MTL and prefrontal regions in retrieval compared to encoding...
  14. ncbi request reprint Characterizing spatial and temporal features of autobiographical memory retrieval networks: a partial least squares approach
    Donna Rose Addis
    Toronto Western Research Institute, Toronto, Ontario, Canada
    Neuroimage 23:1460-71. 2004
    ....
  15. doi request reprint Network alterations supporting word retrieval in patients with medial temporal lobe epilepsy
    Andrea B Protzner
    Department of Neuropsychology, Krembil Neuroscience Centre, University Health Network, 399 Bathurst St, Toronto, ON, Canada
    J Cogn Neurosci 23:2605-19. 2011
    ..This strategy of correlating network changes and off-line behavior may provide a powerful tool for predicting a postoperative decline in language performance...
  16. ncbi request reprint Recollective qualities modulate hippocampal activation during autobiographical memory retrieval
    Donna Rose Addis
    Department of Psychology, University of Toronto, Toronto, Ontario, Canada
    Hippocampus 14:752-62. 2004
    ..These findings are consistent with theories of hippocampal function that emphasize its role in the recollection of multifaceted autobiographical experiences...
  17. doi request reprint Characterizing functional integrity: intraindividual brain signal variability predicts memory performance in patients with medial temporal lobe epilepsy
    Andrea B Protzner
    Department of Psychology, University of Calgary, Alberta, Canada
    J Neurosci 33:9855-65. 2013
    ..Furthermore, this measure can be characterized as a robust biomarker in this clinical setting because it reveals the same pattern regardless of cognitive challenge or task engagement during scanning...
  18. doi request reprint Characterizing the normal developmental trajectory of expressive language lateralization using magnetoencephalography
    Darren S Kadis
    Division of Neurology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Int Neuropsychol Soc 17:896-904. 2011
    ..Findings suggest that adult-typical left hemisphere lateralization emerges from an early bilateral language network, which may explain the pediatric advantage for interhemispheric plasticity of language...
  19. pmc Recollection versus strength as the primary determinant of hippocampal engagement at retrieval
    Melanie Cohn
    Krembil Neuroscience Centre, University Health Network, Fell Pavilion, Toronto, Ontario, Canada
    Proc Natl Acad Sci U S A 106:22451-5. 2009
    ..Together, our results support the notion that it is recollection of context, rather than memory strength, that underlies hippocampal engagement at retrieval...
  20. doi request reprint The immediacy of recollection: the use of the historical present in narratives of autobiographical episodes by patients with unilateral temporal lobe epilepsy
    Lillian Park
    Rotman Research Institute, Baycrest, Toronto, Ontario M6A 2E1, Canada
    Neuropsychologia 49:1171-6. 2011
    ..We provide the first empirical evidence that a linguistic construct can be used to assess the conscious experience that accompanies recollection...
  21. doi request reprint Associative reinstatement: a novel approach to assessing associative memory in patients with unilateral temporal lobe excisions
    Melanie Cohn
    Krembil Neuroscience Centre, University Health Network, Canada
    Neuropsychologia 47:2989-94. 2009
    ..We propose that associative reinstatement provides a sensitive measure of relational memory that is less dependent on strategic processing and therefore more appropriate for evaluating MTL function in patients...
  22. doi request reprint Determinants of autobiographical memory in patients with unilateral temporal lobe epilepsy or excisions
    Marie St-Laurent
    Krembil Neuroscience Center, University Health Network, Canada
    Neuropsychologia 47:2211-21. 2009
    ..The similarity of the impairment between the event-specific and the generic memory conditions also suggests that temporal specificity is not a key determinant of hippocampal engagement in autobiographical retrieval...
  23. doi request reprint Self-reported symptoms of depression and memory dysfunction in survivors of ARDS
    Neill K J Adhikari
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Chest 135:678-87. 2009
    ..Survivors of ARDS have well documented physical limitations, but psychological effects are less clear. We determined the prevalence of self-reported depression and memory dysfunction in ARDS survivors...
  24. doi request reprint Hippocampal size and memory functioning in children and adolescents with congenital hypothyroidism
    Sarah M Wheeler
    The Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Endocrinol Metab 96:E1427-34. 2011
    ..One area of particular weakness is memory, especially on tasks known to be mediated by the hippocampus. However, the hippocampus has not been directly studied in this population...
  25. ncbi request reprint Visual-spatial ability and fMRI cortical activation in surgery residents
    Kyle R Wanzel
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Am J Surg 193:507-10. 2007
    ..In the current study, we used functional magnetic resonance imaging (fMRI) to identify patterns of cortical activation associated with mental rotation ability in those same residents...
  26. ncbi request reprint Memory for famous people in patients with unilateral temporal lobe epilepsy and excisions
    Indre V Viskontas
    Department of Psychology, University of Toronto, Ontario, Canada
    Neuropsychology 16:472-80. 2002
    ..These findings suggest the integrity of temporal structures in both hemispheres is critical for retrieval of detailed semantic information about famous individuals...
  27. ncbi request reprint Material-specific deficits in "remembering" in patients with unilateral temporal lobe epilepsy and excisions
    David A Moscovitch
    Department of Psychology, University of Toronto, Toronto, Canada
    Neuropsychologia 40:1335-42. 2002
    ..We offer this as a novel interpretation of the "remember-know" literature...
  28. pmc Altered resting state brain dynamics in temporal lobe epilepsy can be observed in spectral power, functional connectivity and graph theory metrics
    Maher A Quraan
    Krembil Neuroscience Center and Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    PLoS ONE 8:e68609. 2013
    ..To our knowledge, this is the only study to encompass power, connectivity and graph theory metrics to investigate the reorganization of resting state functional networks in LTLE patients. ..
  29. doi request reprint Episodic memory processes mediated by the medial temporal lobes contribute to open-ended problem solving
    Signy Sheldon
    Department of Psychology, University of Toronto, Toronto, ON, Canada
    Neuropsychologia 49:2439-47. 2011
    ....
  30. doi request reprint The sign of the cross as a learned ictal automatism?
    Richard Wennberg
    Krembil Neuroscience Centre, Toronto Western Hospital, University of Toronto, Toronto, Ont, Canada
    Epilepsy Behav 15:394-8. 2009
    ....
  31. doi request reprint Effects of early thyroid hormone deficiency on children's autobiographical memory performance
    Karen A Willoughby
    Neuroscience and Mental Health Research Program, The Hospital for Sick Children, Toronto, Ontario
    J Int Neuropsychol Soc 19:419-29. 2013
    ..Furthermore, the present study indicates that the CAI is an effective tool for investigating episodic AM impairment in clinical pediatric populations...
  32. doi request reprint Efficacy and tolerability of the modified Atkins diet in adults with pharmacoresistant epilepsy: a prospective observational study
    Mara Smith
    Schulich School of Medicine, University of Western Ontario, London, Ontario, Canada
    Epilepsia 52:775-80. 2011
    ..Recent evidence suggests that a Modified Atkins Diet may be a beneficial form of cotherapy for adult patients with pharmacoresistant epilepsy...
  33. ncbi request reprint Intrahemispheric reorganization of language in children with medically intractable epilepsy of the left hemisphere
    Darren S Kadis
    Department of Psychology, University of Toronto, Toronto, Ontario, CanadaDepartment of Psychology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Int Neuropsychol Soc 13:505-16. 2007
    ..Findings suggest that left hemisphere insult in young children may result in anterior displacement of language within the frontal cortex...
  34. ncbi request reprint Well-being in informal caregivers of survivors of acute respiratory distress syndrome
    Jill I Cameron
    University Health Network, Women s Health Program, Toronto, ON
    Crit Care Med 34:81-6. 2006
    ....
  35. ncbi request reprint Tremor cells in the human thalamus: differences among neurological disorders
    Jason A Brodkey
    Division of Neurosurgery, Toronto Western Hospital, Ontario, Canada
    J Neurosurg 101:43-7. 2004
    ....
  36. ncbi request reprint Intact perceptual and conceptual priming in temporal lobe epilepsy: neuroanatomical and methodological implications
    Rebecca L Billingsley
    Department of Psychology, University of Toronto and The Hospital for Sick Children, Ontario, Canada
    Neuropsychology 16:92-101. 2002
    ..Thus, intact left temporal cortex does not appear to be necessary for normal implicit memory performance, even when conceptual processing is emphasized at study or test...
  37. ncbi request reprint Prefrontal and hippocampal contributions to the generation and binding of semantic associations during successful encoding
    Donna Rose Addis
    Department of Psychology, Harvard University, William James Hall, Rm 854, 33 Kirkland Street, Cambridge, MA 02138, USA
    Neuroimage 33:1194-206. 2006
    ..Our findings illustrate that modulation of components in a memory network can be independent of patterns of mutual connectivity among those components in mediating successful encoding...