David Massel

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi request reprint Potential cost effectiveness of tissue plasminogen activator among patients previously treated with streptokinase
    D Massel
    Department of Medicine, University of Western Ontario, London
    Can J Cardiol 15:173-9. 1999
  2. ncbi request reprint The number needed to harm: is it too optimistic?
    D Massel
    Department of Medicine, University of Western Ontario, London, Canada
    Can J Cardiol 19:1490-2. 2003
  3. ncbi request reprint Observer variability in ECG interpretation for thrombolysis eligibility: experience and context matter
    David Massel
    Department of Medicine, London Health Sciences Centre, University of Western Ontario, Room 205 Colborne Building, Victoria Campus, 375 South Street, London, Ontario, Canada N6A 4G5
    J Thromb Thrombolysis 15:131-40. 2003
  4. ncbi request reprint Primary angioplasty in acute myocardial infarction: Hypothetical estimate of superiority over aspirin or untreated controls
    David Massel
    Department of Medicine, London Health Sciences Centre, University of Western Ontario, London, Canada
    Am J Med 118:113-22. 2005
  5. ncbi request reprint Enoxaparin in acute coronary syndromes: evidence for superiority over placebo or untreated control
    David Massel
    Department of Medicine, London Health Sciences Centre, University of Western Ontario
    Am Heart J 143:748-52. 2002
  6. ncbi request reprint Precision and accuracy of the bedside examination in detecting an ejection fraction of less than 40% following acute myocardial infarction
    D Massel
    Department of Medicine, University of Western Ontario, London, Ontario
    Can J Cardiol 20:411-6. 2004
  7. ncbi request reprint Risks and benefits of adding anti-platelet therapy to warfarin among patients with prosthetic heart valves: a meta-analysis
    D Massel
    Department of Medicine, London Health Sciences Center, University of Western Ontario, Canada
    J Am Coll Cardiol 37:569-78. 2001
  8. ncbi request reprint Greater expectations in a cancer trial: absolute more than relative survival increases, community more than academic clinicians
    D Massel
    Department of Medicine, University of Western Ontario, London, Canada
    Cancer Invest 18:798-803. 2000
  9. ncbi request reprint Strict reliance on a computer algorithm or measurable ST segment criteria may lead to errors in thrombolytic therapy eligibility
    D Massel
    Department of Medicine, London Health Sciences Centre, University of Western Ontario, London, Canada
    Am Heart J 140:221-6. 2000
  10. ncbi request reprint Evidence-based medicine and reteplase: inductive arguments over deductive reasoning
    D Massel
    London Health Sciences Centre, London, Canada
    Can J Cardiol 15:999-1005. 1999

Detail Information

Publications34

  1. ncbi request reprint Potential cost effectiveness of tissue plasminogen activator among patients previously treated with streptokinase
    D Massel
    Department of Medicine, University of Western Ontario, London
    Can J Cardiol 15:173-9. 1999
    ..Accordingly, tissue-type plasminogen activator (t-PA) is frequently administered to patients with recurrent infarction presenting more than four days from previous treatment with streptokinase...
  2. ncbi request reprint The number needed to harm: is it too optimistic?
    D Massel
    Department of Medicine, University of Western Ontario, London, Canada
    Can J Cardiol 19:1490-2. 2003
    ..The NNH may, however, provide an optimistic measure of the true risks caused by therapy...
  3. ncbi request reprint Observer variability in ECG interpretation for thrombolysis eligibility: experience and context matter
    David Massel
    Department of Medicine, London Health Sciences Centre, University of Western Ontario, Room 205 Colborne Building, Victoria Campus, 375 South Street, London, Ontario, Canada N6A 4G5
    J Thromb Thrombolysis 15:131-40. 2003
    ....
  4. ncbi request reprint Primary angioplasty in acute myocardial infarction: Hypothetical estimate of superiority over aspirin or untreated controls
    David Massel
    Department of Medicine, London Health Sciences Centre, University of Western Ontario, London, Canada
    Am J Med 118:113-22. 2005
    ..Knowledge of the effects of PTCA in this setting is useful as a substantial minority of patients do not receive thrombolysis because of contraindications...
  5. ncbi request reprint Enoxaparin in acute coronary syndromes: evidence for superiority over placebo or untreated control
    David Massel
    Department of Medicine, London Health Sciences Centre, University of Western Ontario
    Am Heart J 143:748-52. 2002
    ..Enoxaparin has been shown in 2 trials to be superior to heparin but has not been compared with placebo or untreated control...
  6. ncbi request reprint Precision and accuracy of the bedside examination in detecting an ejection fraction of less than 40% following acute myocardial infarction
    D Massel
    Department of Medicine, University of Western Ontario, London, Ontario
    Can J Cardiol 20:411-6. 2004
    ..Left ventricular function is the most important determinant of prognosis following myocardial infarction...
  7. ncbi request reprint Risks and benefits of adding anti-platelet therapy to warfarin among patients with prosthetic heart valves: a meta-analysis
    D Massel
    Department of Medicine, London Health Sciences Center, University of Western Ontario, Canada
    J Am Coll Cardiol 37:569-78. 2001
    ..The objective of this study was to compare the effectiveness and safety of adding dipyridamole or aspirin to warfarin among patients with prosthetic heart valves using meta-analytic techniques...
  8. ncbi request reprint Greater expectations in a cancer trial: absolute more than relative survival increases, community more than academic clinicians
    D Massel
    Department of Medicine, University of Western Ontario, London, Canada
    Cancer Invest 18:798-803. 2000
    ..Expectations were greatest when the prognosis was poorest and differed between community and academic physicians...
  9. ncbi request reprint Strict reliance on a computer algorithm or measurable ST segment criteria may lead to errors in thrombolytic therapy eligibility
    D Massel
    Department of Medicine, London Health Sciences Centre, University of Western Ontario, London, Canada
    Am Heart J 140:221-6. 2000
    ..We sought to determine whether potential errors in electrocardiographic diagnosis might be a contributing factor...
  10. ncbi request reprint Evidence-based medicine and reteplase: inductive arguments over deductive reasoning
    D Massel
    London Health Sciences Centre, London, Canada
    Can J Cardiol 15:999-1005. 1999
    ..Moreover, for some of the outcome events, and in particular the primary outcome event, the point estimate suggests that reteplase is, in fact, slightly less effective than tissue plasminogen activator...
  11. ncbi request reprint Access to an outpatient cardiology consultation in southwestern Ontario
    D Massel
    The University of Western Ontario, London, Canada
    Can J Cardiol 15:879-83. 1999
    ..To determine whether there were differences in waiting time for a consultation for a nonurgent cardiology problem among specialists in an academic centre compared with those in community practice...
  12. ncbi request reprint Similar, the same or just not different: a guide for deciding whether treatments are clinically equivalent. [Dept. of Medicine, Division of Cardiology, Univ. of Western Ontario, London, Ontario]
    D Massel
    The University of Western Ontario, London, Canada
    Can J Cardiol 15:556-62. 1999
    ..A guide was developed to assist readers in determining whether claims of clinical equivalence are valid...
  13. pmc Ejection fraction assessment and survival: an analysis of the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
    Lorne J Gula
    University of Western Ontario, London, Ontario, Canada
    Am Heart J 156:1196-200. 2008
    ..Evidence suggests that measures of EF by different imaging modalities may not be equivalent. In the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial), the type of imaging modality for EF assessment was not mandated...
  14. doi request reprint Does adenosine response predict clinical recurrence of atrial fibrillation after pulmonary vein isolation?
    Lorne J Gula
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    J Cardiovasc Electrophysiol 22:982-6. 2011
    ..Adenosine can be associated with acute recovery of conduction to the pulmonary veins immediately after isolation. However, it is not known whether this is prognostic for permanent recovery of conduction or recurrence of AF...
  15. doi request reprint Is defibrillation testing still necessary? A decision analysis and Markov model
    Lorne J Gula
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    J Cardiovasc Electrophysiol 19:400-5. 2008
    ..To assess the impact of defibrillation threshold (DFT) testing of implanted cardioverter-defibrillators (ICDs) on survival...
  16. ncbi request reprint Cryoablation versus RF ablation for AVNRT: A meta-analysis and systematic review
    Mikael Hanninen
    Arrhythmia Service, London Health Science Center, London, Ontario, Canada
    J Cardiovasc Electrophysiol 24:1354-60. 2013
    ..High success rates have been accompanied with a small risk of atrioventricular (AV) block. Cryoablation has been used as an alternative to radiofrequency (RF) ablation, but studies have been underpowered in comparing the 2 techniques...
  17. doi request reprint Risk of arrhythmia and sudden death in patients with asymptomatic preexcitation: a meta-analysis
    Manoj N Obeyesekere
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Circulation 125:2308-15. 2012
    ..The purpose of this meta-analysis was to define the incidence of SCD and supraventricular tachycardia in patients with asymptomatic Wolff-Parkinson-White ECG pattern...
  18. doi request reprint Does familiarity with technology predict successful use of an external loop recorder? The loop recorder technology cognition study (LOCO)
    Lorne J Gula
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Pacing Clin Electrophysiol 32:466-72. 2009
    ..We prospectively assessed technological familiarity using a Technology Cognition Questionnaire to determine influence on proper and effective use of an external loop recorder (ELR)...
  19. doi request reprint Impact of routine transoesophageal echocardiography on safety, outcomes, and cost of pulmonary vein ablation: inferences drawn from a decision analysis model
    Lorne J Gula
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Europace 12:1550-7. 2010
    ....
  20. ncbi request reprint Patient reperfusion preferences in acute myocardial infarction: mortality versus stroke, benefits versus costs, high technology versus drugs
    W Tsui
    Department of Medicine, London Health Sciences Centre, University of Western Ontario, London, Canada
    Can J Cardiol 21:423-31. 2005
    ..PCI reduces the risk of death and stroke compared with tPA, but at increased costs. The authors explored patient preferences for the various reperfusion strategies...
  21. ncbi request reprint Survival rates as a guide to implanted cardioverter-defibrillator replacement strategies for device recalls--adding statistical insight to clinical intuition
    Lorne J Gula
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Am Heart J 153:253-9. 2007
    ..The estimated risks are varied through a wide range to determine the potential range of outcomes...
  22. ncbi request reprint The expectation effect and cardiac pacing for refractory vasovagal syncope
    Sachin Sud
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Am J Med 120:54-62. 2007
    ..Clinical trials of pacing for vasovagal syncope have shown conflicting results. We performed a meta-analysis to determine whether permanent pacemaker therapy prevents refractory vasovagal syncope...
  23. doi request reprint Myocardial fibrosis and quality of life in patients with non-ischemic cardiomyopathy: a cardiovascular magnetic resonance imaging study
    Razi Khan
    Division of Cardiology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, 363 Colborne St, Suite 2503, London, ON, N6B 3N3, Canada
    Int J Cardiovasc Imaging 29:395-404. 2013
    ..Therefore, the severity of underlying myocardial tissue disease, a recognized substrate for ventricular arrhythmia, cannot and should not be inferred from the patient's symptom status or QOL...
  24. ncbi request reprint The number remaining at risk: an adjunct to the number needed to treat
    D Massel
    Division of Cardiology, Department of Medicine, University of Western Ontario, London
    Can J Cardiol 18:254-8. 2002
    ..The NRR is a simple index that can easily be calculated from the published results of a clinical trial. As an adjunct to the NNT, it provides a measure of the impact of therapy and the average prognosis of remaining patients...
  25. ncbi request reprint An echocardiographic study of the limitations of the Tei index in aortic stenosis
    Sachin Sud
    Department of Medicine, Division of Cardiology, London Health Sciences Centre, University Campus, University of Western Ontario, Ontario, Canada
    Echocardiography 26:891-9. 2009
    ..However, these time intervals can be influenced by valvular heart disease and the role of the Tei index among patients with aortic stenosis (AS) and left ventricular systolic dysfunction remains incompletely defined...
  26. ncbi request reprint Diagnosing acute myocardial infarction in the setting of left bundle branch block: prevalence and observer variability from a large community study
    Lorne J Gula
    Department of Medicine, University of Western Ontario, London, Canada
    Coron Artery Dis 14:387-93. 2003
    ..We sought to determine the test characteristics and observer reliability of well-known criteria for the diagnosis of AMI when LBBB is present on the electrocardiogram (ECG)...
  27. ncbi request reprint Ejection fraction velocity ratio as an indicator of aortic stenosis severity
    A M Al-Ghamdi
    The Department of Medicine, Division of Cardiology, London Health Sciences Centre, Victoria Campus, University of Western Ontario, London, Ontario, Canada
    Echocardiography 22:195-202. 2005
    ..As such, simpler methods of assessing aortic stenosis severity have been pursued...
  28. ncbi request reprint Model study of AREDS antioxidant supplementation of AMD compared to Visudyne: a dominant strategy?
    John Trevithick
    Department of Biochemistry, Faculty of Medicine, University of Western Ontario, London, Ontario, Canada
    Ophthalmic Epidemiol 11:337-46. 2004
    ....
  29. ncbi request reprint Instruments to measure acceptability of information and acquisition of knowledge in patients with heart failure
    Femida Gwadry-Sridhar
    Division of Cardiology, London Health Sciences Centre, London, Canada
    Eur J Heart Fail 5:783-91. 2003
    ..Providing patients with knowledge through education is one mechanism to help them improve compliance with complicated treatment regimens...
  30. ncbi request reprint External loop recorders: determinants of diagnostic yield in patients with syncope
    Lorne J Gula
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 147:644-8. 2004
    ..The purpose of the current study was to determine the optimal duration of external loop recorder (ELR) monitoring in patients with presyncope or syncope and to identify factors that predict failure to activate the device effectively...
  31. ncbi request reprint Reducing bedrest following arterial puncture for coronary interventional procedures--impact on vascular complications: the BAC Trial
    W Vlasic
    Principal Investigator, BAC Trial, 79 Glenridge Crescent, London, Ontario, Canada, N6G 4W6
    J Invasive Cardiol 13:788-92. 2001
    ..This study was designed to test the hypothesis that reducing time to ambulation from 6 hours to 2 hours would not increase vascular complications...
  32. ncbi request reprint Predictors of intracranial hemorrhage with fibrinolytic therapy in unselected community patients: a report from the FASTRAK II project
    Thao Huynh
    Montreal General Hospital, McGill Health University Center, Montreal, Quebec, Canada
    Am Heart J 148:86-91. 2004
    ..Because the frequency and predictors of ICH reported from these studies may not be widely applicable, we sought to examine this matter further in unselected patients with acute myocardial infarction in the community...
  33. ncbi request reprint Primary angioplasty or thrombolysis for acute myocardial infarction?
    David Massel
    Lancet 361:967; author reply 967-8. 2003
  34. pmc Anticoagulation
    David Massel
    CMAJ 170:447; author reply 451. 2004