R Martin

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. ncbi Multicolor fluorescence in situ hybridization analysis of aneuploidy and diploidy frequencies in 225,846 sperm from 10 normal men
    R H Martin
    Department of Medical Genetics, University of Calgary, Alberta, Canada
    Biol Reprod 54:394-8. 1996
  2. ncbi Chromosomal abnormalities in sperm from testicular cancer patients before and after chemotherapy
    R H Martin
    Department of Genetics, Alberta Children s Hospital, Calgary, Canada
    Hum Genet 99:214-8. 1997
  3. ncbi Analysis of human sperm karyotypes in testicular cancer patients before and after chemotherapy
    R H Martin
    Department of Genetics, Alberta Children s Hospital, Calgary, Canada
    Cytogenet Cell Genet 78:120-3. 1997
  4. ncbi Human sperm chromosome complements in chemotherapy patients and infertile men
    R Martin
    Department of Medical Genetics, University of Calgary, and Department of Genetics, Alberta Children s Hospital, Calgary, Alberta, Canada
    Chromosoma 107:523-7. 1998
  5. ncbi Analysis of aneuploidy for chromosomes 13, 21, X and Y by multicolour fluorescence in situ hybridisation (FISH) in a 47,XYY male
    R H Martin
    Department of Genetics, Alberta Children s Hospital, Calgary, Canada
    Zygote 7:131-4. 1999
  6. ncbi Nondisjunction in human sperm: comparison of frequencies in acrocentric chromosomes
    R H Martin
    Department of Medical Genetics, University of Calgary, Alberta Children s Hospital, Calgary, Alberta, Canada
    Cytogenet Cell Genet 86:43-5. 1999
  7. ncbi Cigarette smoking and aneuploidy in human sperm
    Q Shi
    Department of Medical Genetics, The University of Calgary, Calgary, Alberta, Canada
    Mol Reprod Dev 59:417-21. 2001
  8. ncbi Microwave decondensation and codenaturation: a new methodology to maximize FISH data from donors with very low concentrations of sperm
    E Ko
    Genetics Department, Alberta Children's Hospital, Calgary, Alta, Canada
    Cytogenet Cell Genet 95:143-5. 2001

Collaborators

Detail Information

Publications8

  1. ncbi Multicolor fluorescence in situ hybridization analysis of aneuploidy and diploidy frequencies in 225,846 sperm from 10 normal men
    R H Martin
    Department of Medical Genetics, University of Calgary, Alberta, Canada
    Biol Reprod 54:394-8. 1996
    ..This powerful technology may be useful for future studies of potential environmental and occupational mutagens...
  2. ncbi Chromosomal abnormalities in sperm from testicular cancer patients before and after chemotherapy
    R H Martin
    Department of Genetics, Alberta Children s Hospital, Calgary, Canada
    Hum Genet 99:214-8. 1997
    ..None of the values in the cancer patients differed significantly from 10 normal control donors. Thus our study suggests that BEP chemotherapy does not increase the risk of numerical chromosomal abnormalities in human sperm...
  3. ncbi Analysis of human sperm karyotypes in testicular cancer patients before and after chemotherapy
    R H Martin
    Department of Genetics, Alberta Children s Hospital, Calgary, Canada
    Cytogenet Cell Genet 78:120-3. 1997
    ..Together, these two studies suggest that the sperm of men receiving BEP chemotherapy are not at increased risk of chromosomal abnormalities two or more years after treatment...
  4. ncbi Human sperm chromosome complements in chemotherapy patients and infertile men
    R Martin
    Department of Medical Genetics, University of Calgary, and Department of Genetics, Alberta Children s Hospital, Calgary, Alberta, Canada
    Chromosoma 107:523-7. 1998
    ..Also, FISH analysis for chromosomes 1, 12, 13, 21, XX, YY and XY in 255,613 sperm demonstrated a significant increase in chromosomes 1, 13, 21, and XY disomy in infertile men compared with control donors...
  5. ncbi Analysis of aneuploidy for chromosomes 13, 21, X and Y by multicolour fluorescence in situ hybridisation (FISH) in a 47,XYY male
    R H Martin
    Department of Genetics, Alberta Children s Hospital, Calgary, Canada
    Zygote 7:131-4. 1999
    ..Our results suggest that the extra Y chromosome is eliminated during spermatogenesis in the majority of cells but that there may be a small but significant increase in the frequency of aneuploid sperm in these men...
  6. ncbi Nondisjunction in human sperm: comparison of frequencies in acrocentric chromosomes
    R H Martin
    Department of Medical Genetics, University of Calgary, Alberta Children s Hospital, Calgary, Alberta, Canada
    Cytogenet Cell Genet 86:43-5. 1999
    ..chromosomes 13 and 15; 0.15%) (P < 0.001, Mantel-Haenszel chi(2) test) and other autosomes (chromosomes 1, 2, 4, 9, 12, 13, 15, 16, 18, and 20; 0. 13%) studied in the same men (P < 0.001, Mantel-Haenszel chi(2) test)...
  7. ncbi Cigarette smoking and aneuploidy in human sperm
    Q Shi
    Department of Medical Genetics, The University of Calgary, Calgary, Alberta, Canada
    Mol Reprod Dev 59:417-21. 2001
    ..Mol. Reprod. Dev. 59: 417-421, 2001...
  8. ncbi Microwave decondensation and codenaturation: a new methodology to maximize FISH data from donors with very low concentrations of sperm
    E Ko
    Genetics Department, Alberta Children's Hospital, Calgary, Alta, Canada
    Cytogenet Cell Genet 95:143-5. 2001
    ..There was no significant difference between the frequencies of disomy and diploidy obtained using the two techniques...