Melanie Martin

Summary

Affiliation: University of Winnipeg
Country: Canada

Publications

  1. ncbi request reprint T(2)-weighted microMRI and evoked potential of the visual system measurements during the development of hypomyelinated transgenic mice
    Melanie Martin
    Department of Physics, University of Winnipeg, 515 Portage Avenue, Winnipeg, Manitoba, Canada, R3B 2E9
    Neurochem Res 32:159-65. 2007
  2. ncbi request reprint Myelin deficiencies visualized in vivo: visually evoked potentials and T2-weighted magnetic resonance images of shiverer mutant and wild-type mice
    Melanie Martin
    Biological Imaging Center, Beckman Institute, Division of Biology, California Institute of Technology, Pasadena, CA, USA
    J Neurosci Res 84:1716-26. 2006
  3. doi request reprint Comparison of manual and semi-automated segmentation methods to evaluate hippocampus volume in APP and PS1 transgenic mice obtained via in vivo magnetic resonance imaging
    Kerrie Hayes
    Department of Biology, University of Winnipeg, 515 Portage Avenue, Winnipeg, MB, Canada R3B 2E9 Electronic address
    J Neurosci Methods 221:103-11. 2014
  4. ncbi request reprint Neurofibrillary tangles and plaques are not accompanied by white matter pathology in aged triple transgenic-Alzheimer disease mice
    Marzena Z Kastyak-Ibrahim
    Department of Physics, University of Winnipeg, 515 Portage Avenue, Winnipeg, Manitoba, R3B 2E9, Canada Electronic address
    Magn Reson Imaging 31:1515-21. 2013
  5. ncbi request reprint Digital three-dimensional atlas of quail development using high-resolution MRI
    Seth W Ruffins
    California Institute of Technology, Division of Biology, Biological Imaging Center, Beckman Institute, Pasadena, CA, USA
    ScientificWorldJournal 7:592-604. 2007
  6. ncbi request reprint Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination
    Jonathan D Thiessen
    Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada Department of Radiology, University of Manitoba, Winnipeg, MB, Canada
    NMR Biomed 26:1562-81. 2013
  7. ncbi request reprint Superiority of 3D wavelet-packet denoising in MR microscopy
    Nilesh R Ghugre
    Biomedical Electrical Engineering, University of Southern California, Los Angeles, CA, USA
    Magn Reson Imaging 21:913-21. 2003
  8. doi request reprint Histochemical visualization and diffusion MRI at 7 Tesla in the TgCRND8 transgenic model of Alzheimer's disease
    Jonathan D Thiessen
    Division of Neurodegenerative Disorders, St Boniface Research Centre, Winnipeg, MB, R2H 2A6, Canada
    Brain Struct Funct 215:29-36. 2010
  9. ncbi request reprint Region-specific myelin pathology in mice lacking the golli products of the myelin basic protein gene
    Erin C Jacobs
    Neuropsychiatric Institute, University of California Los Angeles School of Medicine, Los Angeles, California 90024, USA
    J Neurosci 25:7004-13. 2005

Collaborators

  • J Michael Tyszka
  • Seth W Ruffins
  • Ji Ming Feng
  • A Messing
  • Erin C Jacobs
  • Jonathan D Thiessen
  • Richard Buist
  • Kerrie Hayes
  • Xin Min Li
  • Handi Zhang
  • Jiming Kong
  • Yanbo Zhang
  • Marzena Z Kastyak-Ibrahim
  • Marc R Del Bigio
  • Benedict C Albensi
  • Nilesh R Ghugre
  • Junhui Wang
  • Arthur R Summers
  • Trevor J Vincent
  • Sheryl L Herrera
  • Domenico L Di Curzio
  • Lingyan Wang
  • Kathryn A C Glazner
  • Angela E Schellenberg
  • Solmaz Nafez
  • Miriam Scadeng
  • Robia Pautler
  • Russell Jacobs
  • Carol Readhead
  • Timothy Hiltner
  • Christopher Waters
  • John C Wood

Detail Information

Publications9

  1. ncbi request reprint T(2)-weighted microMRI and evoked potential of the visual system measurements during the development of hypomyelinated transgenic mice
    Melanie Martin
    Department of Physics, University of Winnipeg, 515 Portage Avenue, Winnipeg, Manitoba, Canada, R3B 2E9
    Neurochem Res 32:159-65. 2007
    ..Overall these non-invasive techniques are capable of spatially resolving the increase in myelination in the normally developing and developmentally delayed mouse brain...
  2. ncbi request reprint Myelin deficiencies visualized in vivo: visually evoked potentials and T2-weighted magnetic resonance images of shiverer mutant and wild-type mice
    Melanie Martin
    Biological Imaging Center, Beckman Institute, Division of Biology, California Institute of Technology, Pasadena, CA, USA
    J Neurosci Res 84:1716-26. 2006
    ..These data show the potential of using micro MRI in combination with VEPs to follow changes in both the quality and the quantity of myelin in vivo. These combined methods would be useful for longitudinal studies and therapy testing...
  3. doi request reprint Comparison of manual and semi-automated segmentation methods to evaluate hippocampus volume in APP and PS1 transgenic mice obtained via in vivo magnetic resonance imaging
    Kerrie Hayes
    Department of Biology, University of Winnipeg, 515 Portage Avenue, Winnipeg, MB, Canada R3B 2E9 Electronic address
    J Neurosci Methods 221:103-11. 2014
    ..A hallmark pathological feature of Alzheimer's disease is atrophy of the hippocampus, which is an early biomarker of the disease. MRI can be used to detect and monitor this biomarker...
  4. ncbi request reprint Neurofibrillary tangles and plaques are not accompanied by white matter pathology in aged triple transgenic-Alzheimer disease mice
    Marzena Z Kastyak-Ibrahim
    Department of Physics, University of Winnipeg, 515 Portage Avenue, Winnipeg, Manitoba, R3B 2E9, Canada Electronic address
    Magn Reson Imaging 31:1515-21. 2013
    ..Myelin staining was normal in affected mice. These data suggest that the 3xTg-AD mouse model does not develop MRI detectable white matter changes at the ages we examined. ..
  5. ncbi request reprint Digital three-dimensional atlas of quail development using high-resolution MRI
    Seth W Ruffins
    California Institute of Technology, Division of Biology, Biological Imaging Center, Beckman Institute, Pasadena, CA, USA
    ScientificWorldJournal 7:592-604. 2007
    ..This provides a method for the analysis and examination of the spatial relationships among the different types of information within the context of the entire embryo...
  6. ncbi request reprint Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination
    Jonathan D Thiessen
    Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada Department of Radiology, University of Manitoba, Winnipeg, MB, Canada
    NMR Biomed 26:1562-81. 2013
    ..37ƒ - 0.25). Of the calculated MRI metrics, ƒ was the strongest indicator of myelin content, while longitudinal relaxation rates and diffusivity measurements were the strongest indicators of changes in tissue structure...
  7. ncbi request reprint Superiority of 3D wavelet-packet denoising in MR microscopy
    Nilesh R Ghugre
    Biomedical Electrical Engineering, University of Southern California, Los Angeles, CA, USA
    Magn Reson Imaging 21:913-21. 2003
    ..MR microscopy researchers preferred the denoised images to the unprocessed images for their atlas projects...
  8. doi request reprint Histochemical visualization and diffusion MRI at 7 Tesla in the TgCRND8 transgenic model of Alzheimer's disease
    Jonathan D Thiessen
    Division of Neurodegenerative Disorders, St Boniface Research Centre, Winnipeg, MB, R2H 2A6, Canada
    Brain Struct Funct 215:29-36. 2010
    ....
  9. ncbi request reprint Region-specific myelin pathology in mice lacking the golli products of the myelin basic protein gene
    Erin C Jacobs
    Neuropsychiatric Institute, University of California Los Angeles School of Medicine, Los Angeles, California 90024, USA
    J Neurosci 25:7004-13. 2005
    ..Together, all these findings suggest a role for golli proteins in oligodendrocyte differentiation, migration, and/or myelin elaboration in the brain...