Research Topics
| J W MartinSummaryAffiliation: University of Alberta Country: Canada Publications
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Detail Information
Publications
PFOS or PreFOS? Are perfluorooctane sulfonate precursors (PreFOS) important determinants of human and environmental perfluorooctane sulfonate (PFOS) exposure?Jonathan W Martin
Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, University of Alberta, 10 102 Clinical Sciences Building, Edmonton, Alberta, CanadaT6G 2G3
J Environ Monit 12:1979-2004. 2010..Two new source tracking principles are presented and applied to human serum...- Ozonation of oil sands process-affected water accelerates microbial bioremediationJonathan W Martin
Division of Analytical and Environmental Toxicology, Department of Biological Sciences, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
Environ Sci Technol 44:8350-6. 2010..The toxicity of ozonated OSPW to higher organisms needs to be assessed, but there is promise that this technique could be applied to accelerate the bioremediation of large volumes of OSPW in Northern Alberta, Canada... - Bioactivation of fluorotelomer alcohols in isolated rat hepatocytesJonathan W Martin
Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, University of Alberta, 10 102 Clinical Sciences Bldg, Edmonton, Alberta, Canada
Chem Biol Interact 177:196-203. 2009..Further research into the nature of protein modification is warranted for these current-use fluorochemicals... - Comparison of high- and low-resolution electrospray ionization mass spectrometry for the analysis of naphthenic acid mixtures in oil sands process waterJonathan W Martin
Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada
Rapid Commun Mass Spectrom 22:1919-24. 2008.... 
Atmospheric chemistry of perfluoroalkanesulfonamides: kinetic and product studies of the OH radical and Cl atom initiated oxidation of N-ethyl perfluorobutanesulfonamideJ W Martin
Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada
Environ Sci Technol 40:864-72. 2006..Taken together, results suggest a plausible route by which perfluorooctanesulfonamides may serve as atmospheric sources of PFCAs, including perfluorooctanoic acid...- Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatocytesJonathan W Martin
Graduate Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ont, Canada M5S 2S2
Chem Biol Interact 155:165-80. 2005..Preincubation with aminobenzotriazole, but not pyrazole, inhibited the formation of metabolites from all FTOHs, suggesting that their oxidation was catalyzed by P450, not alcohol dehydrogenase... - Atmospheric lifetime of fluorotelomer alcoholsD A Ellis
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, Canada M5S 3H6
Environ Sci Technol 37:3816-20. 2003.... - Biological monitoring of polyfluoroalkyl substances: A reviewMagali Houde
Department of Environmental Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
Environ Sci Technol 40:3463-73. 2006..Continuous monitoring with key sentinel species and standardization of analytical methods are recommended... - Capillary HPLC/QTOF-MS for characterizing complex naphthenic acid mixtures and their microbial transformationM Bataineh
Department of Laboratory Medicine and Pathology, 10-102 Clinical Sciences Building, University of Alberta, Edmonton, AB T6G 2G3, Canada
Anal Chem 78:8354-61. 2006..A biodegradation study revealed that tailings water microorganisms preferentially deplete the least alkyl-substituted fraction and may be responsible for the NA profile in aged tailings water... - Thermolysis of fluoropolymers as a potential source of halogenated organic acids in the environmentD A Ellis
Department of Chemistry, 80 St George Street, University of Toronto, Toronto, Ontario, Canada, M5S 3H6
Nature 412:321-4. 2001.... - Perfluoroalkyl contaminants in a food web from Lake OntarioJonathan W Martin
Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada
Environ Sci Technol 38:5379-85. 2004.... - Isomer profiling of perfluorinated substances as a tool for source tracking: a review of early findings and future applicationsJonathan P Benskin
Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, T6G 2G3, Canada
Rev Environ Contam Toxicol 208:111-60. 2010..Finally, given the recent increase of production of PFOSF-based chemicals, following their 2002 phase out, the ability of using isomer profiles to distinguish between historical and currently produced PFOS may also be possible... - Perfluorooctane sulfonate toxicity, isomer-specific accumulation, and maternal transfer in zebrafish (Danio rerio) and rainbow trout (Oncorhynchus mykiss)Rainie L Sharpe
Department of Biological Sciences, University of Alberta, Edmonton, Alberta T5G 2E9, Canada
Environ Toxicol Chem 29:1957-66. 2010..1 +/- 7.6 microg/g). The isomer profile in eggs was not significantly different from that of adults, suggesting that the maternal transfer of branched and linear PFOS isomers in fish is largely nonisomer specific... - Identification of long-chain perfluorinated acids in biota from the Canadian ArcticJonathan W Martin
Department of Chemistry, University of Toronto, 80 St. George Street, Lash Miller Building, Toronto, Ontario M5S 3H6, Canada
Environ Sci Technol 38:373-80. 2004..Future studies should continue to monitor all fluorinated contaminants and examine the absolute and relative toxicities for this novel suite of PFCAs... - Perfluorooctane sulfonate (PFOS) precursors can be metabolized enantioselectively: principle for a new PFOS source tracking toolYuan Wang
Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada, T6G 2G3
Environ Sci Technol 43:8283-9. 2009.... - Monitoring perfluorinated surfactants in biota and surface water samples following an accidental release of fire-fighting foam into Etobicoke CreekCheryl A Moody
Department of Chemistry, University of Toronto, Ontario, Canada
Environ Sci Technol 36:545-51. 2002..The residence time of perfluorooctanesulfonate in Etobicoke Creek as well as the high bioaccumulation in fish liver suggests that perfluorinated surfactants will persist and bioaccumulate following release into the aquatic environment... - Estimating the in situ biodegradation of naphthenic acids in oil sands process waters by HPLC/HRMSXiumei Han
Department of Laboratory Medicine and Pathology, Division of Analytical and Environmental Toxicology, University of Alberta, Edmonton, Alberta, Canada
Chemosphere 76:63-70. 2009..8-13.6 years. Alternative fate mechanisms to explain the slow disappearance of parent NAs from OSPW are discussed, including adsorption and atmospheric partitioning... - Branched perfluorooctane sulfonate isomer quantification and characterization in blood serum samples by HPLC/ESI-MS(/MS)Nicole Riddell
Wellington Laboratories Inc, Guelph, Ontario, Canada
Environ Sci Technol 43:7902-8. 2009.... - Isomer-specific biotransformation rates of a perfluorooctane sulfonate (PFOS)-precursor by cytochrome P450 isozymes and human liver microsomesJonathan P Benskin
Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine, University of Alberta, Canada
Environ Sci Technol 43:8566-72. 2009.... - Polyfluorinated telomer alcohols and sulfonamides in the North American troposphereNaomi L Stock
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada
Environ Sci Technol 38:991-6. 2004..The nonuniform nature of the spatial distribution of both polyfluorinated sulfonamides and FTOHs is indicative of the importance of point sources for the dissemination of these contaminants in the North American troposphere... - Analytical challenges hamper perfluoroalkyl researchJonathan W Martin
University of Toronto, Canada
Environ Sci Technol 38:248A-255A. 2004 - Maternal exposure to perfluorinated acids and fetal growthMichele P Hamm
Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
J Expo Sci Environ Epidemiol 20:589-97. 2010..These results suggest that maternal PFA exposure has no substantial effect on fetal weight and length of gestation at the concentrations observed in this population... - Disposition of perfluorinated acid isomers in Sprague-Dawley rats; part 2: subchronic doseAmila O De Silva
Department of Chemistry, University of Toronto, Ontario, Canada
Environ Toxicol Chem 28:555-67. 2009.... - Disposition of perfluorinated acid isomers in Sprague-Dawley rats; part 1: single doseJonathan P Benskin
Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alverta, Canada
Environ Toxicol Chem 28:542-54. 2009..Source assignment based on PFA isomer profiles in biota must therefore be conducted with caution, because isomer profiles are unlikely to be conserved in biological samples... - Degradation of fluorotelomer alcohols: a likely atmospheric source of perfluorinated carboxylic acidsDavid A Ellis
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, Canada M5S 3H6
Environ Sci Technol 38:3316-21. 2004..Such reactions are expected to occur during the atmospheric degradation of all polyfluorinated materials, necessitating a reexamination of the environmental fate and impact of this important class of industrial chemicals... - Influence of molecular structure on the biodegradability of naphthenic acidsXiumei Han
Department of Laboratory Medicine and Pathology, Division of Analytical and Environmental Toxicology, 10 102 Clinical Sciences Building, University of Alberta, Edmonton, AB, T6G 2G3, Canada
Environ Sci Technol 42:1290-5. 2008..It is anticipated that these data will facilitate development of strategic solutions for remediating billions of cubic meters of OSPW stored, or predicted to be generated, in Northern Alberta... - Dietary accumulation, disposition, and metabolism of technical pentabrominated diphenyl ether (de-71) in pregnant mink (Mustela vison) and their offspringSi Zhang
Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada
Environ Toxicol Chem 27:1184-93. 2008..On a mass basis, OH-PBDEs accounted for 28 to 32% of the excreted fraction, indicating metabolism was an important elimination pathway. Further studies are required to understand the mechanisms of PBDE biotransformation... - Endogenous high-performance liquid chromatography/tandem mass spectrometry interferences and the case of perfluorohexane sulfonate (PFHxS) in human serum; are we overestimating exposure?Emily Chan
Department of Public Health Sciences, University of Alberta Public Health Sciences10 111 Clinical Sciences Building, Edmonton, Alberta T6G 2G3, Canada
Rapid Commun Mass Spectrom 23:1405-10. 2009..In conclusion, it was shown that routine analytical methods are prone to systematically overestimating PFHxS concentrations in serum of men or women, but that this can be avoided by alternative chromatographic steps or MS/MS transitions... - Simultaneous characterization of perfluoroalkyl carboxylate, sulfonate, and sulfonamide isomers by liquid chromatography-tandem mass spectrometryJonathan P Benskin
Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, 10 102 Clinical Sciences Building, University of Alberta, Edmonton, AB, Canada
Anal Chem 79:6455-64. 2007..This fact, and for reasons of improved accuracy and sensitivity, investigators are urged to utilize more efficient separation methods capable of isomer characterization in perfluoroalkyl research... - Collection of airborne fluorinated organics and analysis by gas chromatography/chemical ionization mass spectrometryJonathan W Martin
Department of Environmental Biology, University of Guelph, Ontario
Anal Chem 74:584-90. 2002..Low concentrations of fluoroorganics were consistently detected in blanks (<4 pg m(-3)); however, this did not prevent confirmation or quantification of environmental concentrations... - Circumpolar study of perfluoroalkyl contaminants in polar bears (Ursus maritimus)Marla Smithwick
Department of Environmental Biology, University of Guelph, Bovey Building, Guelph, Ontario N1G 2W1, Canada
Environ Sci Technol 39:5517-23. 2005.... - Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus mykiss)Jonathan W Martin
University of Guelph, Department of Environmental Biology, Bovey Building, Guelph, Ontario N1G 2W1, Canada
Environ Toxicol Chem 22:196-204. 2003.... - Dietary accumulation of perfluorinated acids in juvenile rainbow trout (Oncorhynchus mykiss)Jonathan W Martin
University of Guelph, Department of Environmental Biology, Bovey Building, Guelph, Ontario N1G 2W1, Canada
Environ Toxicol Chem 22:189-95. 2003..Dietary exposure will not result in biomagnification of PFAs in juvenile trout, but extrapolation of these bioaccumulation parameters to larger fish and homeothermic organisms should not be performed... - Contribution of volatile precursor substances to the flux of perfluorooctanoate to the ArcticUrs Schenker
Institute for Chemical and Bioengineering, ETH Zurich, CH 8093 Zurich, Switzerland
Environ Sci Technol 42:3710-6. 2008.... - Dietary and in utero exposure to a pentabrominated diphenyl ether mixture did not affect cholinergic parameters in the cerebral cortex of ranch mink (Mustela vison)Kimberly Bull
Department of Natural Resource Sciences, McGill University, Macdonald Campus, Sainte Anne de Bellevue, Quebec, Canada H9X 3V9
Toxicol Sci 96:115-22. 2007..This study demonstrated that environmentally relevant exposures to DE-71 did not affect key parameters of the cholinergic neurotransmitter system in the brain of ranch mink... - Airborne haloacetic acidsJonathan W Martin
Department of Environmental Biology, University of Guelph, Bovey Building, Guelph, Ontario, Canada N1G 2W1
Environ Sci Technol 37:2889-97. 2003..A simple deposition model indicated that dry deposition of TFA and TCA should not be neglected in temperate mid-latitude environments and that precipitation concentrations can be successfully predicted by the Henry's law constant... - Perflouroalkyl contaminants in liver tissue from East Greenland polar bears (Ursus maritimus)Marla Smithwick
Department of Environmental Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada
Environ Toxicol Chem 24:981-6. 2005..No significant correlations were found between concentrations of PFCAs in liver tissue and previously reported polychlorinated biphenyl (PCB) congeners analyzed in fat samples from the same bears...