J C Marshall

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Intra-abdominal infections
    John C Marshall
    Department of Surgery and the Interdepartmental Division of Critical Care Medicine, University of Toronto and the Toronto General Hospital, University Health Network, Toronto, Ont, Canada M5G 2C4
    Microbes Infect 6:1015-25. 2004
  2. pmc The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?
    John C Marshall
    University of Toronto, General and Critical Care Surgery, Toronto General Hospital, Toronto, Ontario, Canada
    Crit Care 6:465-7. 2002
  3. ncbi request reprint Such stuff as dreams are made on: mediator-directed therapy in sepsis
    John C Marshall
    Department of Surgery and the Interdepartmental Division of Critical Care Medicine, University of Toronto, Eaton North 9 234, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, Ontario, Canada
    Nat Rev Drug Discov 2:391-405. 2003
  4. ncbi request reprint Measures, markers, and mediators: toward a staging system for clinical sepsis. A report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25-26, 2000
    John C Marshall
    Department of Surgery and Interdepartmental, Division of Critical Care, University of Toronto, Canada
    Crit Care Med 31:1560-7. 2003
  5. ncbi request reprint Intensive care unit management of intra-abdominal infection
    John C Marshall
    Department of Surgery, University of Toronto and Toronto General Hospital, University Health Network, Ontario, Canada
    Crit Care Med 31:2228-37. 2003
  6. ncbi request reprint The effects of granulocyte colony-stimulating factor in preclinical models of infection and acute inflammation
    John C Marshall
    Department of Surgery and the Interdepartmental Division of Critical Care, Toronto General Hospital, University of Toronto, Ontario, Canada
    Shock 24:120-9. 2005
  7. pmc Measurements in the intensive care unit: what do they mean?
    John C Marshall
    Department of Surgery and the Interdepartmental Division of Critical Care Medicine, University of Toronto, and the Toronto General Hospital, University Health Network, Toronto, Canada
    Crit Care 7:415-6. 2003
  8. ncbi request reprint Sepsis: current status, future prospects
    John C Marshall
    Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Curr Opin Crit Care 10:250-64. 2004
  9. pmc Transfusion trigger: when to transfuse?
    John C Marshall
    University of Toronto, Toronto, Ontario, Canada
    Crit Care 8:S31-3. 2004
  10. ncbi request reprint Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study
    John C Marshall
    University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Infect Dis 190:527-34. 2004

Detail Information

Publications71

  1. ncbi request reprint Intra-abdominal infections
    John C Marshall
    Department of Surgery and the Interdepartmental Division of Critical Care Medicine, University of Toronto and the Toronto General Hospital, University Health Network, Toronto, Ont, Canada M5G 2C4
    Microbes Infect 6:1015-25. 2004
    ..Successful management depends on aggressive resuscitation and hemodynamic support, administration of adequate antimicrobial therapy, and the timely use of source control measures appropriate to the clinical situation...
  2. pmc The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?
    John C Marshall
    University of Toronto, General and Critical Care Surgery, Toronto General Hospital, Toronto, Ontario, Canada
    Crit Care 6:465-7. 2002
  3. ncbi request reprint Such stuff as dreams are made on: mediator-directed therapy in sepsis
    John C Marshall
    Department of Surgery and the Interdepartmental Division of Critical Care Medicine, University of Toronto, Eaton North 9 234, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, Ontario, Canada
    Nat Rev Drug Discov 2:391-405. 2003
    ....
  4. ncbi request reprint Measures, markers, and mediators: toward a staging system for clinical sepsis. A report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25-26, 2000
    John C Marshall
    Department of Surgery and Interdepartmental, Division of Critical Care, University of Toronto, Canada
    Crit Care Med 31:1560-7. 2003
    ..The evaluation of effective therapies has been hampered by limitations in our ability to characterize the process and to stratify patients into more homogeneous groups with respect to pathogenesis...
  5. ncbi request reprint Intensive care unit management of intra-abdominal infection
    John C Marshall
    Department of Surgery, University of Toronto and Toronto General Hospital, University Health Network, Ontario, Canada
    Crit Care Med 31:2228-37. 2003
    ..To review the biologic characteristics of, and management approaches to, intra-abdominal infection in the critically ill patient...
  6. ncbi request reprint The effects of granulocyte colony-stimulating factor in preclinical models of infection and acute inflammation
    John C Marshall
    Department of Surgery and the Interdepartmental Division of Critical Care, Toronto General Hospital, University of Toronto, Ontario, Canada
    Shock 24:120-9. 2005
    ..Significant variability in the design and reporting of studies of preclinical models of acute illness precludes more sophisticated data synthesis...
  7. pmc Measurements in the intensive care unit: what do they mean?
    John C Marshall
    Department of Surgery and the Interdepartmental Division of Critical Care Medicine, University of Toronto, and the Toronto General Hospital, University Health Network, Toronto, Canada
    Crit Care 7:415-6. 2003
  8. ncbi request reprint Sepsis: current status, future prospects
    John C Marshall
    Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Curr Opin Crit Care 10:250-64. 2004
  9. pmc Transfusion trigger: when to transfuse?
    John C Marshall
    University of Toronto, Toronto, Ontario, Canada
    Crit Care 8:S31-3. 2004
    ..Arbitrary numeric hemoglobin triggers, however, cannot supercede intervention based on individual physiologic need and clinical circumstances...
  10. ncbi request reprint Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study
    John C Marshall
    University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Infect Dis 190:527-34. 2004
    ..Stepwise logistic regression analysis showed that elevated Acute Physiology and Chronic Health Evaluation II score, gram-negative infection, and emergency admission status were independent predictors of EA...
  11. pmc Measurement of endotoxin activity in critically ill patients using whole blood neutrophil dependent chemiluminescence
    John C Marshall
    Medical Surgical Intensive Care Unit, University Health Network, Toronto, Ontario, Canada
    Crit Care 6:342-8. 2002
    ..The relationship between endotoxaemia, Gram-negative infection and the clinical syndrome of sepsis has been difficult to establish, in part because of the limitations of available endotoxin assays...
  12. ncbi request reprint Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome
    J C Marshall
    Department of Surgery, University Health Network, University of Toronto, Ontario, Canada
    Crit Care Med 29:S99-106. 2001
    ....
  13. ncbi request reprint The gut in critical illness: evidence from human studies
    J C Marshall
    Department of Surgery, University of Toronto, Ontario, Canada
    Shock 6:S10-6. 1996
    ..The challenge to replace them is no less compelling and no less treacherous than it was in the era of Metchnikoff, Lane, or their ancient forebears...
  14. ncbi request reprint A rapid assay of endotoxin in whole blood using autologous neutrophil dependent chemiluminescence
    A D Romaschin
    Department of Clinical Biochemistry, The Toronto Hospital, University of Toronto, Ontario, Canada
    J Immunol Methods 212:169-85. 1998
    ..This was reproducible over a wide range of LPS concentrations (0.017-1.6 EU/ml or 20-2000 pg/ml). This assay may be a clinically useful tool for the diagnosis of infection or endotoxin in patients...
  15. ncbi request reprint Hemorrhagic shock primes for increased expression of cytokine-induced neutrophil chemoattractant in the lung: role in pulmonary inflammation following lipopolysaccharide
    J Fan
    Department of Surgery, The Toronto Hospital, University of Toronto, Ontario, Canada
    J Immunol 161:440-7. 1998
    ....
  16. ncbi request reprint Clinical trials of mediator-directed therapy in sepsis: what have we learned?
    J C Marshall
    Department of Surgery, The University of Toronto, The Toronto General Hospital, Ontario, Canada
    Intensive Care Med 26:S75-83. 2000
    ....
  17. ncbi request reprint The gut as a potential trigger of exercise-induced inflammatory responses
    J C Marshall
    Department of Surgery, University of Toronto, Ontario, Canada
    Can J Physiol Pharmacol 76:479-84. 1998
    ....
  18. pmc Subcutaneous heparin versus low-molecular-weight heparin as thromboprophylaxis in patients undergoing colorectal surgery: results of the canadian colorectal DVT prophylaxis trial: a randomized, double-blind trial
    R S McLeod
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Ann Surg 233:438-44. 2001
    ..To compare the effectiveness and safety of low-dose unfractionated heparin and a low-molecular-weight heparin as prophylaxis against venous thromboembolism after colorectal surgery...
  19. ncbi request reprint Source control in the management of sepsis
    M F Jimenez
    Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Intensive Care Med 27:S49-62. 2001
    ..Moreover evidence-based support for these principles is weak. In the final analysis, the elusive process of experienced surgical judgement is invaluable for all but the most straightforward problems...
  20. doi request reprint Event adjudication and data monitoring in an intensive care unit observational study of thromboprophylaxis
    D Cook
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Crit Care 24:168-75. 2009
    ....
  21. doi request reprint Discordance between perception and treatment practices associated with intensive care unit-acquired bacteriuria and funguria: a Canadian physician survey
    Clarence Chant
    Pharmacy Department, St Michael s Hospital, Toronto, Ontario, Canada
    Crit Care Med 36:1158-67. 2008
    ..To determine physician practice and perception about the management of intensive care unit (ICU)-acquired bacteriuria and funguria...
  22. ncbi request reprint Empiric antimicrobial therapy in critical illness: results of a surgical infection society survey
    Mary Anne W Aarts
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Surg Infect (Larchmt) 8:329-36. 2007
    ..Often, therapy is initiated empirically; practice patterns are not well characterized. We documented approaches to empiric antibiotic therapy among members of the Surgical Infection Society (SIS)...
  23. ncbi request reprint Source control in the management of severe sepsis and septic shock: an evidence-based review
    John C Marshall
    From the Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Crit Care Med 32:S513-26. 2004
    ....
  24. ncbi request reprint DNR directives are established early in mechanically ventilated intensive care unit patients
    Tasnim Sinuff
    Department of Medicine, McMaster University Health Sciences Center, Room 2C11, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Can J Anaesth 51:1034-41. 2004
    ..Our objective was to study the rate of establishing do-not-resuscitate (DNR) directives, determinants, and outcomes of those directives for mechanically ventilated patients...
  25. ncbi request reprint Antibiotic management of suspected nosocomial ICU-acquired infection: does prolonged empiric therapy improve outcome?
    Mary Anne W Aarts
    University of Toronto, Interdepartmental Division of Critical Care Medicine and the Department of Surgery, Toronto, Canada
    Intensive Care Med 33:1369-78. 2007
    ..To characterize empiric antibiotic use in patients with suspected nosocomial ICU-acquired infections (NI), and determine the impact of prolonged therapy in the absence of infection...
  26. ncbi request reprint Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels
    Edward A Panacek
    Department of Medicine, University of California Davis Medical Center, Sacramento, CA, USA
    Crit Care Med 32:2173-82. 2004
    ..To evaluate whether administration of afelimomab, an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment, would reduce 28-day all-cause mortality in patients with severe sepsis and elevated serum levels of IL-6...
  27. ncbi request reprint Outcome measures for clinical research in sepsis: a report of the 2nd Cambridge Colloquium of the International Sepsis Forum
    John C Marshall
    Department of Surgery, Interdepartmental Division of Critical Care Medicine, University of Toronto, St Michael s Hospital, Canada
    Crit Care Med 33:1708-16. 2005
    ..We sought to evaluate existing approaches and to draw on insights from other disciplines to propose a comprehensive approach to outcome evaluation in sepsis clinical trials...
  28. ncbi request reprint Lipopolysaccharide: an endotoxin or an exogenous hormone?
    John C Marshall
    Interdepartmental Division of Critical Care Medicine, Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Clin Infect Dis 41:S470-80. 2005
    ..Thus, LPS is not less an endotoxin than an exohormone, and its neutralization may potentially result in either benefit or harm...
  29. doi request reprint Sepsis: rethinking the approach to clinical research
    John C Marshall
    Department of Surgery and Critical Care Medicine, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada
    J Leukoc Biol 83:471-82. 2008
    ....
  30. pmc Iatrogenesis, inflammation and organ injury: insights from a murine model
    John C Marshall
    University of Toronto, St Michael s Hospital, 30 Bond St Rm 4 007, Bond Wing, Toronto, Ontario, Canada M5B 1W8
    Crit Care 10:173. 2006
    ....
  31. pmc The staging of sepsis: understanding heterogeneity in treatment efficacy
    John C Marshall
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Crit Care 9:626-8. 2005
    ..They will be no less important in the optimal management of sepsis...
  32. ncbi request reprint Neutralization of tumor necrosis factor in preclinical models of sepsis
    Jose A Lorente
    Department of Critical Care Medicine, Hospital Universitario de Getafe, Madrid, Spain
    Shock 24:107-19. 2005
    ....
  33. ncbi request reprint Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury
    Lauralyn A McIntyre
    Centre for Transfusion and Critical Care Research, Clinical Epidemiology Unit, Critical Care Program, University of Ottawa and Ottawa Health Research Institute, Ottawa, Ontario
    Neurocrit Care 5:4-9. 2006
    ..To compare a restrictive versus a liberal transfusion strategy in patients with moderate to severe closed head injury following multiple trauma in 13 Canadian intensive care units (ICUs)...
  34. ncbi request reprint Surgical decision-making: integrating evidence, inference, and experience
    John C Marshall
    Departments of Surgery and Critical Care Medicine, University of Toronto, St Michael s Hospital, 4th Floor Bond Wing, Room 4 007, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8
    Surg Clin North Am 86:201-15, xii. 2006
    ....
  35. ncbi request reprint Controversies in sepsis clinical trials: proceedings of a meeting of the International Sepsis Forum, Lausanne, Switzerland, September 29, 2001
    R Phillip Dellinger
    Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08854, USA
    J Crit Care 21:38-47. 2006
    ..Once a therapy is approved, adopting less stringent but still appropriate criteria for the use of that therapy in clinical practice may be appropriate...
  36. ncbi request reprint Daily variation in endotoxin levels is associated with increased organ failure in critically ill patients
    David J Klein
    St Michael s Hospital, University of Toronto, Ontario, Canada
    Shock 28:524-9. 2007
    ..Further studies are warranted to assess the role of daily variation in endotoxin levels in the pathogenesis and potential therapy of organ failure in the critically ill...
  37. ncbi request reprint Intraabdominal infections in infants and children: descriptions and definitions
    Ann E Thompson
    Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine, PA, USA
    Pediatr Crit Care Med 6:S30-5. 2005
    ..To define intraabdominal infections in infants and children...
  38. ncbi request reprint 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
    Mitchell M Levy
    Rhode Island Hospital, Brown University School of Medicine, 593 Eddy Street, Providence, RI 02903, USA
    Crit Care Med 31:1250-6. 2003
    ..Nevertheless, there has been an impetus from experts in the field to modify these definitions to reflect our current understanding of the pathophysiology of these syndromes...
  39. ncbi request reprint Saturday night fever: finding and controlling the source of sepsis in critical illness
    Sandro B Rizoli
    Department of Surgery, Interdepartmental Division of Critical Care, Sepsis Research Laboratories, Toronto General Hospital, University of Toronto, Ontario, Canada
    Lancet Infect Dis 2:137-44. 2002
    ....
  40. ncbi request reprint Monocyte adhesion and transmigration induce tissue factor expression: role of the mitogen-activated protein kinases
    Ian D McGilvray
    Department of Surgery, University of Toronto and University Health Network, Ontario, Canada
    Shock 18:51-7. 2002
    ..The selective inhibition of the mitogen-activated protein kinases may offer a novel therapeutic means of modulating this inflammatory sequence...
  41. ncbi request reprint In defense of evidence: the continuing saga of selective decontamination of the digestive tract
    Mary Anne Aarts
    Am J Respir Crit Care Med 166:1014-5. 2002
  42. ncbi request reprint 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
    Mitchell M Levy
    Rhode Island Hospital, 593 Eddy Street, MICU Main 7, Providence RI 02903, USA
    Intensive Care Med 29:530-8. 2003
    ..Nevertheless, there has been an impetus from experts in the field to modify these definitions to reflect our current understanding of the pathophysiology of these syndromes...
  43. pmc The PIRO concept: R is for response
    Herwig Gerlach
    Department of Anaesthesiology and Intensive Care Medicine, Vivantes Klinikum Neukoelln, Germany
    Crit Care 7:256-9. 2003
  44. pmc The PIRO concept: O is for organ dysfunction
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
    Crit Care 7:260-4. 2003
  45. ncbi request reprint Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity
    Ravi Taneja
    Department of Surgery, The Toronto General Hospital, University Health Network, University of Toronto, Ontario, Canada
    Crit Care Med 32:1460-9. 2004
    ....
  46. pmc Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis
    Song Hui Jia
    Department of Surgery, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada
    J Clin Invest 113:1318-27. 2004
    ..These data identify PBEF as a novel inflammatory cytokine that plays a requisite role in the delayed neutrophil apoptosis of clinical and experimental sepsis...
  47. ncbi request reprint Measuring organ dysfunction in the intensive care unit: why and how?
    John C Marshall
    Can J Anaesth 52:224-30. 2005
  48. ncbi request reprint Modulating neutrophil apoptosis
    John C Marshall
    Department of Surgery, Interdepartmental Division of Critical Care Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    Novartis Found Symp 280:53-66; discussion 67-72, 160-4. 2007
    ..A complex series of interactions between the neutrophil and microorganisms or their products regulates the duration and intensity of an inflammatory response, and so provides an attractive target for therapeutic manipulation...
  49. ncbi request reprint Judging the angles formed by visible and imaginary clock hands: a study of hemispatial effects in healthy volunteers
    Juraj Kukolja
    Institute of Medicine, Forschungszentrum Julich, Julich, Germany
    Cortex 40:329-37. 2004
    ..No such operation is required in the perceptual condition where the hands are clearly visible...
  50. ncbi request reprint Hypertonic preconditioning prevents hepatocellular injury following ischemia/reperfusion in mice: a role for interleukin 10
    George D Oreopoulos
    Department of Surgery, University Health Network and University of Toronto, Toronto, Ontario, Canada
    Hepatology 40:211-20. 2004
    ....
  51. ncbi request reprint Regulation of Toll-like receptor 4 expression in the lung following hemorrhagic shock and lipopolysaccharide
    Jie Fan
    Department of Surgery, University Health Network, St Michael s Hospital and University of Toronto, Toronto, Ontario, Canada
    J Immunol 168:5252-9. 2002
    ....
  52. ncbi request reprint Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8
    Song Hui Jia
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    J Biol Chem 283:5402-13. 2008
    ....
  53. doi request reprint Pre-B cell colony-enhancing factor (PBEF)/visfatin: a novel mediator of innate immunity
    Tracy Luk
    Department of Surgery and the Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Ontario, Canada
    J Leukoc Biol 83:804-16. 2008
    ..This review summarizes the admittedly incomplete body of emerging knowledge about a remarkable new mediator of innate immunity...
  54. doi request reprint Temporal activation patterns of lateralized cognitive and task control processes in the human brain
    Rene Gobbele
    Department of Neurology, University Hospital Aachen, RWTH Aachen, Germany
    Brain Res 1205:81-90. 2008
    ..In addition, activation of ACC prior and after this differential activation is consistent with previous findings suggesting that this area may be involved in cognitive control...
  55. ncbi request reprint Through a glass darkly: the brave new world of in silico modeling
    John C Marshall
    Crit Care Med 32:2157-9. 2004
  56. pmc Surviving sepsis: a guide to the guidelines
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Route de Lennik 808, B 1070 Brussels, Belgium
    Crit Care 12:162. 2008
    ..The revised guidelines are far from perfect, but they represent the best available synthesis of contemporary knowledge in this area and as such should be promoted...
  57. ncbi request reprint Up-regulation of functional CXCR4 expression on human lymphocytes in sepsis
    Ziqiang Ding
    Division of Thoracic Surgery, Department of Surgery, Toronto General Research Institute of the University Health Network, University of Toronto, Toronto, ON, Canada
    Crit Care Med 34:3011-7. 2006
    ..The purpose of this study was to examine chemokine receptor expression and function in lymphocytes from septic patients and healthy donors...
  58. ncbi request reprint ARDS and the multiple organ dysfunction syndrome. Common mechanisms of a common systemic process
    Rachel G Khadaroo
    Department of Surgery, Interdepartmental Division of Critical Care, Sepsis Research Laboratories, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    Crit Care Clin 18:127-41. 2002
    ..The growing recognition that iatrogenic factors contribute to the expression of MODS has highlighted the need for the clinician to be aware of the potential for harm inherent with every intervention...
  59. ncbi request reprint Neural mechanisms underlying spatial judgements on seen and imagined visual stimuli in the left and right hemifields in men
    Juraj Kukolja
    Institute of Medicine, Cognitive Neurology Group, Research Centre Julich, Germany
    Neuropsychologia 44:2846-60. 2006
    ..Overall, our findings converge with neuropsychological data showing that representational and visuospatial neglect do not always co-occur...
  60. ncbi request reprint Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
    R Phillip Dellinger
    Crit Care Med 32:858-73. 2004
    ....
  61. ncbi request reprint Burden of illness in venous thromboembolism in critical care: a multicenter observational study
    Rakesh Patel
    Department of Medicine, University of Ottawa, Canada K1Y 4E9
    J Crit Care 20:341-7. 2005
    ....
  62. ncbi request reprint Neutrophils in the pathogenesis of sepsis
    John C Marshall
    St Michael s Hospital, Toronto, Ontario, Canada
    Crit Care Med 33:S502-5. 2005
  63. ncbi request reprint Left inferior parietal cortex integrates time and space during collision judgments
    Ann Assmus
    Institute of Medicine, Research Center Julich, 52425, Julich, Germany
    Neuroimage 20:S82-8. 2003
    ..Furthermore, the data suggest that the left supramarginal gyrus combines temporal and spatial variables more widely than previously supposed...
  64. ncbi request reprint Preclinical models of shock and sepsis: what can they tell us?
    John C Marshall
    St Michael s Hospital, Toronto, Ontario, Canada
    Shock 24:1-6. 2005
    ..Hence, greater model standardization would aid in interpreting data and in pooling results into systematic data syntheses: such efforts should be promoted and undertaken...
  65. ncbi request reprint Cerebral localization, then and now
    John C Marshall
    University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK
    Neuroimage 20:S2-7. 2003
    ....
  66. ncbi request reprint Twenty-five percent albumin prevents lung injury following shock/resuscitation
    Kinga A Powers
    Department of Surgery, University Health Network, Toronto, Canada
    Crit Care Med 31:2355-63. 2003
    ....
  67. ncbi request reprint Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
    R Phillip Dellinger
    Section of Critical Care Medicine, Cooper University Hospital, One Cooper Plaza, 393 Dorrance, Camden, NJ 08103, USA
    Intensive Care Med 30:536-55. 2004
    ....
  68. ncbi request reprint Modeling MODS: what can be learned from animal models of the multiple-organ dysfunction syndrome?
    John C Marshall
    Intensive Care Med 31:605-8. 2005
  69. ncbi request reprint Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome
    Yumiko Imai
    Department of Critical Care, St Michael s Hospital, University of Toronto, Toronto, Ontario
    JAMA 289:2104-12. 2003
    ..Recent clinical trials have demonstrated a decrease in multiple organ dysfunction syndrome (MODS) and mortality in patients with acute respiratory distress syndrome (ARDS) treated with a protective ventilatory strategy...
  70. ncbi request reprint The pathogenesis and molecular biology of sepsis
    John C Marshall
    Department of Surgery, and Interdepartmental Division of Critical Care Medicine, University of Toronto, Ontario, Canada
    Crit Care Resusc 8:227-9. 2006
  71. ncbi request reprint The surviving sepsis campaign
    John C Marshall
    Crit Care Resusc 8:181-2. 2006