Research Topics
| Carlo MarraSummaryAffiliation: University of British Columbia Country: Canada Publications
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Detail Information
Publications
Willingness to pay to assess patient preferences for therapy in a Canadian settingCarlo A Marra
Pharmaceutical Sciences Clinical Service Unit, Vancouver Hospital and Health Sciences Centre, Vancouver British Columbia, Canada
BMC Health Serv Res 5:43. 2005..The purpose of this study was to elicit treatment location preferences and willingness to pay (WTP) from patients referred to an OPAT program...- Rheumatoid arthritis: a primer for pharmacistsCarlo Marra
Arthritis Research Centre of Canada, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
Am J Health Syst Pharm 63:S4-10. 2006..Traditional and newer scoring instruments to measure disease severity, progression, disability, and response to therapy are reviewed and introduced, respectively. The impact of RA on disability and quality of life (QOL) is also explored... - A comparison of generic, indirect utility measures (the HUI2, HUI3, SF-6D, and the EQ-5D) and disease-specific instruments (the RAQoL and the HAQ) in rheumatoid arthritisCarlo A Marra
Faculty of Pharmaceutical Sciences, University of British Columbia, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, 717 828 West 10th Ave, Vancouver, BC, Canada V6Z 1Y6
Soc Sci Med 60:1571-82. 2005..We conclude that the all of the preference-based utility measures that were evaluated appear to adequately discriminate across levels of RA severity... - Factors influencing quality of life in patients with active tuberculosisCarlo A Marra
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
Health Qual Life Outcomes 2:58. 2004..The objective of our study was to identify areas of QoL that are affected by active TB using focus groups and individual interviews... - Health state utility values: a description of their development and application for rheumatic diseasesNick Bansback
Centre for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada
Arthritis Rheum 59:1018-26. 2008 - Using the health assessment questionnaire to estimate preference-based single indices in patients with rheumatoid arthritisNick Bansback
St Paul s Hospital, Vancouver, British Columbia, Canada
Arthritis Rheum 57:963-71. 2007.... - Are indirect utility measures reliable and responsive in rheumatoid arthritis patients?Carlo A Marra
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
Qual Life Res 14:1333-44. 2005..However, differences in the magnitude of the absolute change scores have important implications for cost-effectiveness analyses... - An assessment of quality of sleep and the use of drugs with sedating properties in hospitalized adult patientsLuciana Frighetto
Pharmaceutical Sciences Clinical Service Unit, Vancouver Hospital and Health Sciences Center, 855 West 12th Avenue, Vancouver, BC, Canada
Health Qual Life Outcomes 2:17. 2004..The primary objectives of this study were to assess sleep disturbance and its determinants including the use of drugs with sedating properties... - Economic burden of asthma: a systematic reviewKatayoun Bahadori
Centre for Clinical Epidemiology and Evaluation C2E2, UBC, Vancouver, BC, Canada
BMC Pulm Med 9:24. 2009..It is also associated with the loss of future potential earnings related to both morbidity and mortality. The objective of the study is to determine the burden of disease costs associated with asthma... - Technical note: acceptability curves could be misleading when correlated strategies are comparedMohsen Sadatsafavi
University of British Columbia, Vancouver, Canada
Med Decis Making 28:306-7. 2008 - Meta-analysis of basiliximab for immunoprophylaxis in renal transplantationPaul Keown
Department of Medicine, University of British Columbia, Vancouver, British Columbia and Syreon Corporation, Vancouver, British Columbia, Canada
BioDrugs 17:271-9. 2003..However, incorporation of basiliximab immunoprophylaxis into routine practice depends upon the demonstration of benefit across treatment regimens and quantitation of the treatment effect... - A comparison of four indirect methods of assessing utility values in rheumatoid arthritisCarlo A Marra
Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada
Med Care 42:1125-31. 2004..Agreement among the instruments was moderate but poorer at lower utilities. It is unlikely that these utility values, if used as the weightings for quality-adjusted life years, would result in comparable estimates... - Measuring health-related quality of life in tuberculosis: a systematic reviewNa Guo
Faculty of Pharmaceutical Sciences, Collaboration for Outcomes Research and Evaluation, University of British Columbia, Vancouver, BC, Canada
Health Qual Life Outcomes 7:14. 2009..The objectives of this study were to better understand the impact of tuberculosis and its treatment on people's quality of life, and to review quality of life instruments used in current tuberculosis research... - Pharmacists' preferences for providing patient-centered services: a discrete choice experiment to guide health policyKelly A Grindrod
University of British Columbia, Vancouver, Canada
Ann Pharmacother 44:1554-64. 2010..In Canada, most pharmacists are not paid to provide patient-centered services. In other areas of the world these services have suffered from poor adoption by pharmacists... - Do visual analogue scale (VAS) derived standard gamble (SG) utilities agree with Health Utilities Index utilities? A comparison of patient and community preferences for health status in rheumatoid arthritis patientsAmir Adel Rashidi
Centre for Clinical Epidemiology and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Canada
Health Qual Life Outcomes 4:25. 2006..The objective of this study is to assess the agreement between community preferences derived from the Health Utilities Index Mark 2 (HUI2) and Mark 3 (HUI3) systems, and patient preferences... - Ontario's plunging price-caps on generics: deeper dives may drown some drugsAslam Anis
Health Economics in the School of Population and Public Health, University of British Columbia, Vancouver
Open Med 5:e149-52. 2011..Generic product substitution legislation is vital to reducing costs to provincial drug plans, yet lower and lower price-caps may undo some of the benefits of substitution legislation if generics find it difficult to survive... - Effectiveness and cost effectiveness of human papillomavirus vaccine: a systematic reviewFawziah Marra
University of British Columbia, Vancouver, British Columbia, Canada
Pharmacoeconomics 27:127-47. 2009.... - The economic impact of obstructive sleep apneaNayef AlGhanim
Department of Medicine, University of British Columbia, and Respiratory Division, Vancouver General Hospital, British Columbia, Canada
Lung 186:7-12. 2008..Governments, transportation agencies, industry, and insurance companies need to be better informed concerning the economic impact of untreated OSA and the benefits of therapy... - Cost-effectiveness of LTBI treatment for TB contacts in British ColumbiaMichael C Tan
Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada
Value Health 11:842-52. 2008..Knowing the cost-effectiveness of LTBI therapy for specific TB contact subpopulations may improve the use of limited resources by reducing the treatment of persons at low TB risk... - The validity of generic and condition-specific preference-based instruments: the ability to discriminate asthma control statusHelen M McTaggart-Cowan
Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, 7th Floor, 828 West 10th Avenue, Vancouver, BC, Canada, V5Z 1L8
Qual Life Res 17:453-62. 2008..The objective of this study was to evaluate the validity of generic and condition-specific preference-based instruments, in terms of their ability to distinguish asthma control... - An economic model of 2-hour post-dose ciclosporin monitoring in renal transplantationPaul A Keown
University of British Columbia, Vancouver, British Columbia, Canada
Pharmacoeconomics 22:621-32. 2004..A predictive decision model was used to determine if this approach also reduces total treatment costs in the first 12 months after renal transplantation... - Reliability studies of diagnostic tests are not using enough observers for robust estimation of interobserver agreement: a simulation studyMohsen Sadatsafavi
Center for Health Evaluation and Outcome Research CHEOS, University of British Columbia, Vancouver BC, Canada V6Z 1Y6
J Clin Epidemiol 61:722-7. 2008..We attempted to study the effect of readers' variation on two measures of multireader reliability: pair-wise agreement and Fleiss' kappa... - An ounce of prevention is worth a pound of cure: a cost-effectiveness analysis of incidentally detected aneurysms in functional MRI researchMohsen Sadatsafavi
Collaboration for Outcome Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada
Value Health 13:761-9. 2010..We applied a decision-analytic approach to assess the benefit of various strategies for functional MRI (fMRI) studies using intracranial aneurysms (IA) as a model... - Cost-effectiveness of continuous positive airway pressure therapy for moderate to severe obstructive sleep apnea/hypopneaNajib T Ayas
Department of Medicine and Division of Respiratory Medicine, University of British Columbia, Vancouver, BC, Canada
Arch Intern Med 166:977-84. 2006..CONCLUSION: When quality of life, costs of therapy, and MVC outcomes are considered, CPAP therapy for patients with OSAH is economically attractive... - Quality-of-life assessment in an outpatient parenteral antibiotic programAlan F Goodfellow
Pharmaceutical Sciences Clinical Service Unit, Vancouver Hospital and Health Sciences Centre, British Columbia, Canada
Ann Pharmacother 36:1851-5. 2002..CONCLUSIONS: This study reveals that some domains in HRQoL appear to improve 4 weeks after discharge for adults enrolled in an OPAT program and that there are different predictors for changes in physical and mental health... - The "Lost NNT" can be used to represent uncertainty surrounding number needed to treatMohsen Sadatsafavi
Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver, BC, Canada
J Clin Epidemiol 65:863-8. 2012..However, it is not clear how the CI can help inform treatment decisions. We developed decision-theoretic measures of uncertainty for the NNT... - Failing bodies: body image and multiple chronic conditions in later lifeLaura Hurd Clarke
School of Human Kinetics, University of British Columbia, Vancouver, British Columbia, Canada
Qual Health Res 18:1084-95. 2008..We discuss how the participants view their bodies as both aesthetic and instrumental entities and how gender norms and discourses of successful aging and healthism shape their body evaluations... - Considerations and preliminary proposals for defining a reference case for economic evaluations in ankylosing spondylitisNick Bansback
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, British Columbia, Canada
J Rheumatol 34:1178-83. 2007..Ten methodological issues are presented that will be important for future development of evaluations. Tentative proposals to define the issues in a reference case for AS are made, along with recommendations for further research... - Short-term influence of adalimumab on work productivity outcomes in patients with rheumatoid arthritisWei Zhang
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, Vancouver, British Columbia, Canada
J Rheumatol 35:1729-36. 2008..To evaluate the shortterm effect of adalimumab on work productivity in patients with moderate to severe active rheumatoid arthritis (RA)... - After patients are diagnosed with knee osteoarthritis, what do they do?Kelly A Grindrod
University of British Columbia, Vancouver, British Columbia, Canada
Arthritis Care Res (Hoboken) 62:510-5. 2010..To learn more about the health services and products that patients use after receiving a diagnosis of knee osteoarthritis (OA), as well as the trajectory of their health-related quality of life (HRQOL)... - The independent contribution of executive functions to health related quality of life in older womenJennifer C Davis
Centre for Hip Health and Mobility, University of British Columbia and Vancouver Coastal Health Research Institute VCHRI, 301 2647 Willow Street, Vancouver, British Columbia, V5Z 3P1, Canada
BMC Geriatr 10:16. 2010..We calculated QALYs from the EQ-5D administered at baseline, 6 months and 12 months... - The economics of treatment in early rheumatoid arthritisNick Bansback
Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, BC, Canada
Best Pract Res Clin Rheumatol 23:83-92. 2009..With many services competing to spend often limited health-care budgets, information on the relative benefits and costs of new approaches for treating RA can be useful in deciding on efficient allocation and treatment decisions... - Antibiotic use in children is associated with increased risk of asthmaFawziah Marra
University of British Columbia, Faculty of Pharmaceutical Sciences, Centre for Health Evaluation and Outcomes Sciences, St Paul s Hospital, 620 1081 Burrard St, Vancouver, British Columbia, Canada
Pediatrics 123:1003-10. 2009..Antibiotic exposure in early childhood is a possible contributor to the increasing asthma prevalence in industrialized countries. Although a number of published studies have tested this hypothesis, the results have been conflicting... - Levofloxacin treatment of active tuberculosis and the risk of adverse eventsFawziah Marra
University of British Columbia, Vancouver, BC, Canada
Chest 128:1406-13. 2005..Despite increasing use of these agents, there is little information on their tolerance outside of clinical trial settings... - When patients have to pay a share of drug costs: effects on frequency of physician visits, hospital admissions and filling of prescriptionsAslam H Anis
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC
CMAJ 173:1335-40. 2005..We investigated the effect of prescription drug cost-sharing on overall health care utilization among elderly patients with rheumatoid arthritis... - Health economic evaluation: a primer for the practicing rheumatologistMichael C Y Tan
Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada
Arthritis Rheum 55:648-56. 2006 - Cost effectiveness of herpes zoster vaccine in CanadaMehdi Najafzadeh
Collaboration for Outcomes Research and Evaluation CORE, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
Pharmacoeconomics 27:991-1004. 2009..The lifetime risk of HZ is about 20-30% and the incidence increases with age. The protective effect of the HZ vaccine has been shown in a large clinical trial; however, the effectiveness of the vaccine decreased with age of vaccination... - Cost-effectiveness of self-managed versus physician-managed oral anticoagulation therapyDean A Regier
Collaboration for Outcomes Research and Evaluation, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, BC
CMAJ 174:1847-52. 2006..INTERPRETATION: This model suggests that self-management is a cost-effective strategy for those receiving long-term oral anticoagulation therapy for atrial fibrillation or for a mechanical heart valve... - Patterns of use and patients' attitudes toward complementary medications: a survey of adult general medicine patients at a major Canadian teaching hospitalTroy Frederick Cook
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
Can J Clin Pharmacol 9:183-9. 2002.... - Practical pharmacogenetics: the cost effectiveness of screening for thiopurine s-methyltransferase polymorphisms in patients with rheumatological conditions treated with azathioprineCarlo A Marra
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
J Rheumatol 29:2507-12. 2002..CONCLUSION: The introduction of PCR testing to identify TPMT polymorphisms prior to AZA treatment may represent good value in certain health care settings... - Infliximab treatment of rheumatoid arthritis and Crohn's diseaseIbrahim K Nahar
Division of Rheumatology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
Ann Pharmacother 37:1256-65. 2003.... - A case for rimantadine to be marketed in Canada for prophylaxis of influenza A virus infectionFawziah Marra
Faculty of Pharmaceutical Sciences, University of British Columbia and British Columbia Centre for Disease Control, Vancouver, Canada
Can Respir J 10:381-8. 2003..To evaluate the efficacy and safety of amantadine and rimantadine, the first generation antivirals, for the prophylaxis of influenza virus... - Influence of standardized orders on postoperative nausea and vomiting after gynecologic surgeryEdith St Pierre
Clinical Services Unit, Pharmaceutical Sciences, Vancouver Hospital and Health Sciences Centre, Vancouver General Hospital Site, Vancouver, BC, Canada
Ann Pharmacother 36:210-7. 2002..CONCLUSIONS: The implementation of preprinted order forms for PONV prophylaxis and treatment appears to be an effective and economically attractive strategy... - Parental perceived value of a diagnosis for intellectual disability (ID): a qualitative comparison of families with and without a diagnosis for their child's IDNancy L Makela
Collaboration for Outcomes Research and Evaluation CORE, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
Am J Med Genet A 149:2393-402. 2009..Surprisingly, between the two groups there were no differences in the parents' perceptions or experiences related to the presence or absence of an etiological diagnosis for their child's ID... - Cost-effectiveness of oral appliances in the treatment of obstructive sleep apnoea-hypopnoeaMohsen Sadatsafavi
Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, BC, Canada
Sleep Breath 13:241-52. 2009..Oral appliances (OA) are commonly prescribed for the treatment of obstructive sleep apnoea-hypopnoea (OSAH), but there is limited evidence on their cost-effectiveness... - Health-related quality of life trajectories among adults with tuberculosis: differences between latent and active infectionCarlo A Marra
Collaboration for Outcome Research and Evaluation, Faculty of Pharmacetical Sciences, University of British Columbia, Vancouver, BC, Canada
Chest 133:396-403. 2008..Tuberculosis (TB) remains a public health threat with significant annual impacts on morbidity and mortality. However, few studies have examined the impact of active and latent TB infection (LTBI) on health-related quality of life (HRQL)... - Health state utilities in latent and active tuberculosisNa Guo
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
Value Health 11:1154-61. 2008..Numerous cost-effectiveness analyses of TB screening and treatment strategies have been recently published, but none have utilized quality-adjusted life-years as recommended because of the lack of utilities for TB health states... - Abatacept: a novel treatment for moderate-to-severe rheumatoid arthritisJennifer Reynolds
Division of Rheumatology, Faculty of Medicine, University of British Columbia, Vancouver, Canada
Pharmacotherapy 27:1693-701. 2007..However, additional clinical trials evaluating its long-term effect on patient safety and disease outcomes are needed... - Does antibiotic exposure during infancy lead to development of asthma?: a systematic review and metaanalysisFawziah Marra
Health Economics Program, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, Faculty of Pharmaceutical Sciences, University of BC, 828 W Tenth Avenue, Vancouver, BC, V5Z 1L8 Canada
Chest 129:610-8. 2006..Because of the limitations of the studies conducted to date, additional large-scale, prospective studies are needed to confirm this potential association... - Improving osteoarthritis detection in the community: pharmacist identification of new, diagnostically confirmed osteoarthritisCarlo A Marra
Collaboration for Outcomes Research and Evaluation, University of British Columbia, Centre for Clinical Epidemiology and Evaluation, British Columbia, Canada
Arthritis Rheum 57:1238-44. 2007..Our objective was to determine if pharmacists, using a simple screening questionnaire, can identify individuals with previously undiagnosed knee OA... - Physical activity as a mediator of the impact of chronic conditions on quality of life in older adultsRichard Sawatzky
Nursing Department, Trinity Western University, 7600 Langley, British Columbia, V2Y 1Y1, Canada
Health Qual Life Outcomes 5:68. 2007..We examined whether physical activity mediates the relationship between different chronic conditions and several health outcomes that are important to the quality of life of older adults... - An overview of economic evaluations for drugs used in rheumatoid arthritis : focus on tumour necrosis factor-alpha antagonistsNick J Bansback
Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK
Drugs 65:473-96. 2005.... - Evolution of clinical pharmacy in the practice of rheumatologyAyana K Rowley
Department of Pharmacy, Clinical Center, National Institutes of Health, Bethesda, MD, USA
Ann Pharmacother 41:1705-7. 2007 - Evaluating health-related quality-of-life studies in paediatric populations: some conceptual, methodological and developmental considerations and recent applicationsMirella De Civita
Department of Medicine, McGill University, Montreal, Province of Quebec, Canada
Pharmacoeconomics 23:659-85. 2005..In addition, many of the concerns in the development of HR-QOL instruments should also be applied to the utility scales such that they reflect adequately children's preferences for health states...