B J Manns

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. ncbi request reprint The epidemiology of severe sepsis syndrome and its treatment with recombinant human activated protein C
    Christopher James Doig
    Department of Critical Care Medicine, Faculty of Medicine, University of Calgary, Calgary AB, T2N 2T9, Canada
    Expert Opin Pharmacother 4:1789-99. 2003
  2. pmc Activated protein C: cost-effective or costly?
    Savtaj Singh Brar
    Crit Care 11:164. 2007
  3. pmc The effects of nocturnal hemodialysis compared to conventional hemodialysis on change in left ventricular mass: rationale and study design of a randomized controlled pilot study
    Michael Walsh
    Department of Medicine, University of Calgary, Calgary, Canada
    BMC Nephrol 7:2. 2006
  4. pmc Prevention of catheter lumen occlusion with rT-PA versus heparin (Pre-CLOT): study protocol of a randomized trial [ISRCTN35253449]
    Brenda R Hemmelgarn
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 7:8. 2006
  5. pmc Trace elements in hemodialysis patients: a systematic review and meta-analysis
    Marcello Tonelli
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    BMC Med 7:25. 2009
  6. ncbi request reprint The economics of end-stage renal disease care in Canada: incentives and impact on delivery of care
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, T2N 2T9, AB, Canada
    Int J Health Care Finance Econ 7:149-69. 2007
  7. ncbi request reprint The impact of education on chronic kidney disease patients' plans to initiate dialysis with self-care dialysis: a randomized trial
    Braden J Manns
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 68:1777-83. 2005
  8. ncbi request reprint The Southern Alberta Renal Program database: a prototype for patient management and research initiatives
    B J Manns
    Department of Medicine, University of Calgary, Alta
    Clin Invest Med 24:164-70. 2001
  9. ncbi request reprint Quality of life in patients treated with hemodialysis or peritoneal dialysis: what are the important determinants?
    B Manns
    Department of Medicine, Foothills Medical Center, University of Calgary, Alberta, Canada
    Clin Nephrol 60:341-51. 2003
  10. ncbi request reprint Illustrating the impact of including future costs in economic evaluations: an application to end-stage renal disease care
    Braden Manns
    Department of Medicine, Division of Nephrology, University of Calgary, Canada
    Health Econ 12:949-58. 2003

Collaborators

Detail Information

Publications77

  1. ncbi request reprint The epidemiology of severe sepsis syndrome and its treatment with recombinant human activated protein C
    Christopher James Doig
    Department of Critical Care Medicine, Faculty of Medicine, University of Calgary, Calgary AB, T2N 2T9, Canada
    Expert Opin Pharmacother 4:1789-99. 2003
    ..This review discusses the epidemiology of sepsis, preclinical and clinical evidence supporting the use of rhAPC use, controversies about the evidence of efficacy in severe sepsis syndrome and cost-effectiveness data...
  2. pmc Activated protein C: cost-effective or costly?
    Savtaj Singh Brar
    Crit Care 11:164. 2007
    ....
  3. pmc The effects of nocturnal hemodialysis compared to conventional hemodialysis on change in left ventricular mass: rationale and study design of a randomized controlled pilot study
    Michael Walsh
    Department of Medicine, University of Calgary, Calgary, Canada
    BMC Nephrol 7:2. 2006
    ..We have undertaken a multi-center RCT in hemodialysis patients comparing the effect of NHD to CvHD on left ventricular (LV) mass, as measured by cardiac magnetic resonance imaging (cMR)...
  4. pmc Prevention of catheter lumen occlusion with rT-PA versus heparin (Pre-CLOT): study protocol of a randomized trial [ISRCTN35253449]
    Brenda R Hemmelgarn
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 7:8. 2006
    ..The Prevention of Catheter Lumen Occlusion with rt-PA versus Heparin (PreCLOT) study will determine if use of weekly rt-PA, compared to regular heparin, as a catheter locking solution, will decrease the risk of catheter malfunction...
  5. pmc Trace elements in hemodialysis patients: a systematic review and meta-analysis
    Marcello Tonelli
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    BMC Med 7:25. 2009
    ..We conducted a systematic review to summarize existing literature on trace element status in hemodialysis patients...
  6. ncbi request reprint The economics of end-stage renal disease care in Canada: incentives and impact on delivery of care
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, T2N 2T9, AB, Canada
    Int J Health Care Finance Econ 7:149-69. 2007
    ..This paper explains how ESRD care fits into the Canadian health care system, describes the epidemiology of ESRD in Canada, and offers economic explanations for international discrepancies...
  7. ncbi request reprint The impact of education on chronic kidney disease patients' plans to initiate dialysis with self-care dialysis: a randomized trial
    Braden J Manns
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 68:1777-83. 2005
    ....
  8. ncbi request reprint The Southern Alberta Renal Program database: a prototype for patient management and research initiatives
    B J Manns
    Department of Medicine, University of Calgary, Alta
    Clin Invest Med 24:164-70. 2001
    ..Programs caring for patients with chronic medical conditions such as ESRD should examine how computer databases could assist in clinical care and improve the efficiency with which that care is delivered to their patients...
  9. ncbi request reprint Quality of life in patients treated with hemodialysis or peritoneal dialysis: what are the important determinants?
    B Manns
    Department of Medicine, Foothills Medical Center, University of Calgary, Alberta, Canada
    Clin Nephrol 60:341-51. 2003
    ..In part, this is due to the intrusiveness of the treatment (hemodialysis or peritoneal dialysis) that is required. It is unclear whether hemodialysis or peritoneal dialysis is associated with a higher HRQOL...
  10. ncbi request reprint Illustrating the impact of including future costs in economic evaluations: an application to end-stage renal disease care
    Braden Manns
    Department of Medicine, Division of Nephrology, University of Calgary, Canada
    Health Econ 12:949-58. 2003
    ....
  11. doi request reprint Nocturnal hemodialysis does not improve overall measures of quality of life compared to conventional hemodialysis
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 75:542-9. 2009
    ....
  12. ncbi request reprint Establishment and maintenance of vascular access in incident hemodialysis patients: a prospective cost analysis
    Braden Manns
    Department of Medicine, University of Calgary, Alberta, Canada
    J Am Soc Nephrol 16:201-9. 2005
    ..01). Vascular access care is responsible for a significant proportion of health care costs in the first year of hemodialysis. These results support clinical practice guidelines that recommend preferential placement of a native fistula...
  13. ncbi request reprint An economic evaluation of activated protein C treatment for severe sepsis
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    N Engl J Med 347:993-1000. 2002
    ....
  14. ncbi request reprint Restricting cadaveric kidney transplantation based on age: the impact on efficiency and equity
    R R Quinn
    Department of Medicine, Division of Nephrology, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada
    Transplant Proc 39:1362-7. 2007
    ..When compared to long-term dialysis as a therapy for ESRD, kidney transplantation increases survival, improves quality of life, and is cost saving...
  15. doi request reprint A description of the costs of living and standard criteria deceased donor kidney transplantation
    L Barnieh
    Department of Community Health Sciences Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Transplant 11:478-88. 2011
    ..Living donor kidney transplantation has similar costs at 2 years compared with deceased donor transplantation. These results can be used by health care decision makers to inform strategies to increase donation...
  16. pmc Population based screening for chronic kidney disease: cost effectiveness study
    Braden Manns
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMJ 341:c5869. 2010
    ..To determine the cost effectiveness of one-off population based screening for chronic kidney disease based on estimated glomerular filtration rate...
  17. ncbi request reprint Progression of kidney dysfunction in the community-dwelling elderly
    B R Hemmelgarn
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 69:2155-61. 2006
    ..Strategies aimed at slowing progression of kidney disease should consider underlying risk factors for progression and the negligible loss of kidney function that occurs in the majority of older adults...
  18. ncbi request reprint Cost of intensive care unit-acquired bloodstream infections
    K B Laupland
    Department of Critical Care Medicine, University of Calgary, Calgary Health Region, Calgary, Alberta, Canada
    J Hosp Infect 63:124-32. 2006
    ..These data support expenditures on infection prevention and control programmes and further research into reducing the impact of these infections...
  19. ncbi request reprint The routine use of high-resolution immunological screening of recipients of primary deceased donor kidney allografts is cost-effective
    Kevin McLaughlin
    Division of Nephrology, University of Calgary, Calgary, Alberta, Canada
    Transplantation 81:1278-84. 2006
    ..The objective of this study was to evaluate the cost-effectiveness of routine use of high-resolution flow-cytometry cross-matching and solid-phase screening for all recipients of primary deceased donor kidney transplants...
  20. ncbi request reprint Cost analysis of ongoing care of patients with end-stage renal disease: the impact of dialysis modality and dialysis access
    Helen Lee
    Department of Economics, University of Calgary, Alberta, Canada
    Am J Kidney Dis 40:611-22. 2002
    ..Care of patients with end-stage renal disease (ESRD) is important and resource intense. To enable ESRD programs to develop strategies for more cost-efficient care, an accurate estimate of the cost of caring for patients with ESRD is needed...
  21. pmc Residence location and likelihood of kidney transplantation
    Marcello Tonelli
    Division of Nephrology and Transplant Immunology, Department of Medicine, University of Alberta, Edmonton, Alta
    CMAJ 175:478-82. 2006
    ..Within each region we also determined whether distance from the closest transplant centre was associated with the likelihood of transplantation...
  22. doi request reprint Why do patients choose self-care dialysis?
    Kevin McLaughlin
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, AB, Canada
    Nephrol Dial Transplant 23:3972-6. 2008
    ..Our objectives were to identify perceived advantages of SCD associated with increased odds of selecting SCD, and to evaluate the effect of an educational intervention on patients' perceptions of these advantages...
  23. doi request reprint Economic evaluation of dialysis therapies
    Scott Klarenbach
    Department of Medicine, Division of Nephrology, University of Alberta, Edmonton, Alberta, T6G 2G3 Canada
    Semin Nephrol 29:524-32. 2009
    ..There is some evidence to suggest that the modality of home nocturnal dialysis may offer improvements in clinical outcomes including quality of life, but further study of the cost effectiveness of this modality is required...
  24. ncbi request reprint Why patients with ESRD do not select self-care dialysis as a treatment option
    Kevin McLaughlin
    Department of Medicine, Division of Nephrology, University of Calgary and Foothills Hospital, Calgary, Alberta, Canada
    Am J Kidney Dis 41:380-5. 2003
    ..The purpose of this study is to describe reasons in-center hemodialysis patients choose not to perform self-care dialysis and identify variables associated with a negative attitude toward self-care dialysis...
  25. doi request reprint The effect of increasing dialysis dose in overweight hemodialysis patients on quality of life: a 6-week randomized crossover trial
    Wenjie Wang
    Department of Medicine, Division of Nephrology, University of Calgary, Foothills Medical Center, Calgary, Alberta, Canada
    Am J Kidney Dis 51:796-803. 2008
    ..Whether increasing dialysis adequacy in large patients not achieving KDOQI targets improves HRQL is unknown...
  26. pmc Death and renal transplantation among Aboriginal people undergoing dialysis
    Marcello Tonelli
    Department of Medicine, Division of Nephrology, University of Alberta, Edmonton, Alta
    CMAJ 171:577-82. 2004
    ..We evaluated differences in survival and rate of renal transplantation among Aboriginal and white patients after initiation of dialysis...
  27. ncbi request reprint A systematic review of the effect of nocturnal hemodialysis on blood pressure, left ventricular hypertrophy, anemia, mineral metabolism, and health-related quality of life
    Michael Walsh
    Department of Medicine, University of Calgary, Alberta, Canada
    Kidney Int 67:1500-8. 2005
    ..A systematic review of the current available literature was undertaken to examine the effect of nocturnal hemodialysis on key health outcomes...
  28. ncbi request reprint Development of a survey to identify barriers to living donation in kidney transplant candidates
    Lianne Barnieh
    University of Calgary, Calgary, Alberta, Canada
    Prog Transplant 19:304-11. 2009
    ..Numerous barriers may impede the identification of, and transplantation from, living donors...
  29. ncbi request reprint Home care assistance and the utilization of peritoneal dialysis
    M J Oliver
    Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Kidney Int 71:673-8. 2007
    ..Barriers to self-care PD are very common in the elderly ESRD population but home care assistance significantly increases the number of patients who can be safely offered PD...
  30. ncbi request reprint Detailed cost analysis of care for survivors of severe sepsis
    Helen Lee
    Centre for Health and Policy Studies, University of Calgary, Alberta, Canada
    Crit Care Med 32:981-5. 2004
    ..The objectives of our study were to accurately describe the costs and resources required to treat survivors of severe sepsis subsequent to hospital discharge and to determine what factors influenced these costs...
  31. doi request reprint Economic evaluation of erythropoiesis-stimulating agents for anemia related to cancer
    Scott Klarenbach
    Department of Medicine, University of Alberta Edmonton, Alberta, Canada
    Cancer 116:3224-32. 2010
    ..Concerns about toxicity have led to more restrictive recommendations for ESA use; however, the incremental costs and benefits of such a strategy are unknown...
  32. pmc Modeling survival of arteriovenous accesses for hemodialysis: semiparametric versus parametric methods
    Pietro Ravani
    Department of Medicine, Division of Nephrology, University of Calgary, Foothills Medical Centre, 1403 29th St NW, Calgary, AB, T2N2T9, Canada
    Clin J Am Soc Nephrol 5:1243-8. 2010
    ..Comparing outcomes of arteriovenous grafts and fistulas is challenging because the pathophysiology of access dysfunction and failure rate profiles differ by access type. Studying how risks vary over time may be important...
  33. doi request reprint Relation between kidney function, proteinuria, and adverse outcomes
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 303:423-9. 2010
    ..Although proteinuria is also associated with adverse outcomes, it is not used to refine risk estimates of adverse events in this current system...
  34. pmc Association between proximity to the attending nephrologist and mortality among patients receiving hemodialysis
    Marcello Tonelli
    Division of Nephrology and Transplant Immunology, Department of Medicine, University of Alberta, Edmonton, Alta
    CMAJ 177:1039-44. 2007
    ..We investigated whether patients receiving hemodialysis who live farther from their attending nephrologist are more likely to die than those who live closer...
  35. ncbi request reprint Dialysate potassium and risk of death in chronic hemodialysis patients
    Ghassan Al-Ghamdi
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    J Nephrol 23:33-40. 2010
    ..Few data guide the prescription of dialysate potassium (dK) in hemodialysis, which is usually prescribed empirically on the basis of predialysis serum potassium levels...
  36. doi request reprint Economic evaluation of continuous renal replacement therapy in acute renal failure
    Scott Klarenbach
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Int J Technol Assess Health Care 25:331-8. 2009
    ..Controversy exists regarding the optimal method of providing dialysis in critically ill patients with acute renal failure. We sought to determine the cost-effectiveness of treatment strategies...
  37. doi request reprint Phosphate removal with several thrice-weekly dialysis methods in overweight hemodialysis patients
    Marcello Tonelli
    Department of Medicine, University of Alberta, Edmonton, Canada
    Am J Kidney Dis 54:1108-15. 2009
    ..Whether modifying dialysis prescription to intensify small-solute clearance also leads to better phosphate clearance is unknown...
  38. ncbi request reprint A systematic review of sevelamer in ESRD and an analysis of its potential economic impact in Canada and the United States
    Braden Manns
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 66:1239-47. 2004
    ..The objective of this study is to use the example of sevelamer to outline the information that is needed to assist health care payers with the decision to fund a new and expensive therapy...
  39. ncbi request reprint Costing health care procedures: art or science?
    Gillian R Currie
    Department of Economics, University of Calgary, Calgary, Canada
    Can J Gastroenterol 16:467-9. 2002
  40. doi request reprint Nephrology visits and health care resource use before and after reporting estimated glomerular filtration rate
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 303:1151-8. 2010
    ..Laboratory reporting of estimated glomerular filtration rate (GFR) has been widely implemented, with limited evaluation...
  41. pmc Histopathologic features aid in predicting risk for progression of IgA nephropathy
    Michael Walsh
    Division of Nephrology, Foothills Medical Centre, Calgary, AB, T2N 0L9, Canada
    Clin J Am Soc Nephrol 5:425-30. 2010
    ..Accurately identifying patients who are at risk for progressive disease is challenging. The extent to which histopathologic features improves prognostication is uncertain...
  42. ncbi request reprint Systematic review of the clinical efficacy and safety of sevelamer in dialysis patients
    Marcello Tonelli
    Foothills Medical Centre, 1403 29th Street NW, Calgary, Alberta T2N 2T9, Canada
    Nephrol Dial Transplant 22:2856-66. 2007
    ..The relative effectiveness and safety of sevelamer for treatment of hyperphosphataemia in dialysis patients is uncertain, as compared with calcium-based phosphate binders...
  43. ncbi request reprint Heparin induced thrombocytopaenia secondary to intraperitoneal heparin exposure
    Gilaad G Kaplan
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Nephrol Dial Transplant 20:2561-2. 2005
  44. ncbi request reprint Cost of acute renal failure requiring dialysis in the intensive care unit: clinical and resource implications of renal recovery
    Braden Manns
    Department of Medicine, University of Calgary, Alberta, Canada
    Crit Care Med 31:449-55. 2003
    ..As such, the objective of this study was to estimate the cost of CRRT and intermittent hemodialysis in the intensive care unit and to explore the impact of renal recovery on subsequent clinical outcomes and costs among survivors...
  45. doi request reprint Renal replacement therapy in patients with acute renal failure: a systematic review
    Neesh Pannu
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    JAMA 299:793-805. 2008
    ..Acute renal failure requiring dialytic support is associated with a high risk of mortality and substantial morbidity...
  46. pmc Relation between access blood flow and mortality in chronic hemodialysis patients
    Mohammed Al-Ghonaim
    Department of Medicine, University of Alberta, Edmonton, Canada
    Clin J Am Soc Nephrol 3:387-91. 2008
    ..Patients were followed from the date of Qa measurement until death; follow-up was discontinued at loss to follow-up, kidney transplantation, or end of study...
  47. ncbi request reprint To reuse or not to reuse? An economic evaluation of hemodialyzer reuse versus conventional single-use hemodialysis for chronic hemodialysis patients
    Braden J Manns
    University of Calgary
    Int J Technol Assess Health Care 18:81-93. 2002
    ....
  48. ncbi request reprint In the dark: the reporting of blinding status in randomized controlled trials
    Victor M Montori
    Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Clin Epidemiol 55:787-90. 2002
    ..Until such reporting occurs, clinicians will be left with uncertainty about the validity of RCTs that guide their clinical practice...
  49. ncbi request reprint Adapting the Charlson Comorbidity Index for use in patients with ESRD
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Kidney Dis 42:125-32. 2003
    ..The purpose of this study is to assess the validity of the Charlson index in incident dialysis patients and modify the index for use specifically in this patient population...
  50. ncbi request reprint The cost-effectiveness of maintaining higher hemoglobin targets with erythropoietin in hemodialysis patients
    Marcello Tonelli
    Division of Nephrology, University of Alberta, Edmonton, Alberta, Canada
    Kidney Int 64:295-304. 2003
    ..There is uncertainty regarding the appropriate target hemoglobin level in hemodialysis patients treated with erythropoietin (EPO)...
  51. ncbi request reprint Economic evaluation in critical care medicine
    Heather L Cox
    Department of Surgery, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada T2L 2K8
    J Crit Care 21:117-24. 2006
    ..This article highlights the need for randomized clinical trials and economic evaluations of therapies in critical care medicine for which the effect of the therapy on health outcomes and/or costs are unknown...
  52. ncbi request reprint Dialysis adequacy and health related quality of life in hemodialysis patients
    Braden J Manns
    Department of Medicine, University of Calgary, Alberta, Canada
    ASAIO J 48:565-9. 2002
    ..Dialysis adequacy was significantly associated with HRQOL in hemodialysis patients. Controlled studies that examine the effect of increasing Kt/V on HRQOL are needed...
  53. pmc Comorbidities do not influence primary fistula success in incident hemodialysis patients: a prospective study
    Wenjie Wang
    Division of Nephrology, University of Calgary, Foothills Medical Center, Calgary, Canada
    Clin J Am Soc Nephrol 3:78-84. 2008
    ..Concern about primary fistula failure may contribute to the underuse of arteriovenous fistula. The objective of this study was to investigate the baseline clinical parameters associated with primary fistula success...
  54. ncbi request reprint An economic evaluation of operative compared with nonoperative management of displaced intra-articular calcaneal fractures
    Carmen A Brauer
    Harvard Center for Risk Analysis, Harvard School of Public Health, 718 Huntington Avenue, Boston, MA 02115, USA
    J Bone Joint Surg Am 87:2741-9. 2005
    ..We performed an economic evaluation, based on the results of a randomized clinical trial, to evaluate the economic implications of operative compared with nonoperative management of this fracture...
  55. ncbi request reprint Differences in use of peritoneal dialysis and survival among East Asian, Indo Asian, and white ESRD patients in Canada
    Brenda R Hemmelgarn
    Department of Medicine, Division of Nephrology, University of Calgary, Canada
    Am J Kidney Dis 48:964-71. 2006
    ..Racial differences in health outcomes in general are well documented; however, few studies examined the impact of East Asian and Indo Asian race on choice of dialytic modality and survival among patients with end-stage renal disease (ESRD)...
  56. ncbi request reprint The reporting of methodological factors in randomized controlled trials and the association with a journal policy to promote adherence to the Consolidated Standards of Reporting Trials (CONSORT) checklist
    P J Devereaux
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Control Clin Trials 23:380-8. 2002
    ..Until these inadequacies are resolved health-care providers will remain limited in their ability to make informed inferences about the validity of the studies upon which they base their clinical practice...
  57. ncbi request reprint Association between multidisciplinary care and survival for elderly patients with chronic kidney disease
    Brenda R Hemmelgarn
    Department of Medicine, Community Health Schiences, University of Calgary, Calgary, Canada
    J Am Soc Nephrol 18:993-9. 2007
    ..The benefits of MDC and an assessment of their economic impact should be tested in a randomized, controlled trial...
  58. ncbi request reprint Impact of anemia on hospitalization and mortality in older adults
    Bruce F Culleton
    Department of Medicine, University of Calgary, Foothills Hospital, Rm C210, 1403 29th St NW, Calgary, AB, Canada T2N 2T9
    Blood 107:3841-6. 2006
    ..Consideration should be given to redefine "normal" hemoglobin values in the elderly. Clinical trials are also necessary to determine whether anemia correction improves quality or quantity of life in this population...
  59. ncbi request reprint Use of the U.S. and U.K. scoring algorithm for the EuroQol-5D in an economic evaluation of cardiac care
    Fiona M Shrive
    Department of Community Health Sciences, Centre for Health and Policy Studies at the University of Calgary, Calgary, Alberta, Canada
    Med Care 45:269-73. 2007
    ..We recently published an economic evaluation assessing the use of drug-eluting stents in patients undergoing percutaneous coronary intervention (PCI)...
  60. ncbi request reprint NSAID use and progression of chronic kidney disease
    Katherine Gooch
    Institute of Health Economics, Edmonton, Alberta, Canada
    Am J Med 120:280.e1-7. 2007
    ..Due to the high prevalence of both CKD and NSAID use in older adults, we sought to determine the association between NSAID use and the progression of CKD in an elderly community-based cohort...
  61. ncbi request reprint Defining the optimal treatment of locally advanced esophageal cancer: a systematic review and decision analysis
    Andrew J Graham
    Department of Surgery, Division of Thoracic Surgery, University of Calgary, Institute of Health Economics, Calgary, Alberta, Canada
    Ann Thorac Surg 83:1257-64. 2007
    ..The objective of this study was to combine systematic review and decision analytic techniques to determine the optimal treatment strategy for patients with locally advanced esophageal cancer...
  62. ncbi request reprint Managing anemia. What do we do now? Views from Canada
    David C Mendelssohn
    Humber River Regional Hospital, Toronto, Ontario, Canada
    Nephrol News Issues 21:55-7. 2007
  63. pmc Economic evaluation of sirolimus-eluting stents
    Fiona M Shrive
    Department of Community Health Sciences, University of Calgary, Calgary, Alta
    CMAJ 172:345-51. 2005
    ..Given that sirolimus-eluting stents cost about 4 times as much as conventional stents, and considering the volume of PCI procedures, the decision to use sirolimus-eluting stents has large economic implications...
  64. ncbi request reprint Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial
    Bruce F Culleton
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 298:1291-9. 2007
    ..Morbidity and mortality rates in hemodialysis patients remain excessive. Alterations in the delivery of dialysis may lead to improved patient outcomes...
  65. ncbi request reprint Acetylcysteine in the prevention of contrast-induced nephropathy: a case study of the pitfalls in the evolution of evidence
    Sean M Bagshaw
    Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada
    Arch Intern Med 166:161-6. 2006
    ....
  66. pmc Cost-effectiveness of computerized tomographic colonography versus colonoscopy for colorectal cancer screening
    Steven J Heitman
    Department of Medicine, University of Calgary, Calgary, Alta
    CMAJ 173:877-81. 2005
    ..Its main advantage, a better safety profile, may be offset by its limitations: lower sensitivity, need for colonoscopy in cases where results are positive, and expense...
  67. ncbi request reprint Double blind, you have been voted off the island!
    P J Devereaux
    McMaster University, Hamilton, Ontario, Canada
    Evid Based Ment Health 5:36-7. 2002
  68. ncbi request reprint Cost-effectiveness of hemofiltration to prevent contrast nephropathy in patients with chronic kidney disease
    Scott W Klarenbach
    Department of Medicine, Division of Nephrology, University of Alberta, Canada
    Crit Care Med 34:1044-51. 2006
    ..We sought to explore the potential scope and cost-effectiveness of this strategy...
  69. ncbi request reprint Double blind, you are the weakest link--good-bye!
    P J Devereaux
    ACP J Club 136:A11. 2002
  70. ncbi request reprint An observational study found that authors of randomized controlled trials frequently use concealment of randomization and blinding, despite the failure to report these methods
    P J Devereaux
    Department of Medicine, Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Room 2C8, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    J Clin Epidemiol 57:1232-6. 2004
    ..We undertook an observational study to determine whether concealment of randomization or blinding was used in RCTs that failed to report these bias-reducing strategies...
  71. ncbi request reprint Vitamin B12 decreases, but does not normalize, homocysteine and methylmalonic acid in end-stage renal disease: a link with glycine metabolism and possible explanation of hyperhomocysteinemia in end-stage renal disease
    Matthew Eric Hyndman
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Metabolism 52:168-72. 2003
    ..05). High-dose vitamin therapy significantly lowers, but does not normalize, MMA and tHcy levels. The MTHFR genotype, while influencing homocysteine levels, was not responsible for the majority of the elevation in plasma tHcy...
  72. pmc Access to health care among status Aboriginal people with chronic kidney disease
    Song Gao
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, AB
    CMAJ 179:1007-12. 2008
    ..We determined whether access to care differed between status Aboriginal people (Aboriginal people registered under the federal Indian Act) and non-Aboriginal people with chronic kidney disease...
  73. doi request reprint Nonmedical costs of colorectal cancer screening with the fecal occult blood test and colonoscopy
    Steven J Heitman
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 6:912-917.e1. 2008
    ..The nonmedical costs of colorectal cancer screening are unknown. However, they might influence screening uptake and impact the cost-effectiveness of colorectal cancer screening modalities...
  74. ncbi request reprint Moving beyond the cost per quality-adjusted life year: modelling the budgetary impact and clinical outcomes associated with the use of sirolimus-eluting stents
    Fiona M Shrive
    Department of Community Health Sciences, University of Calgary, Canada
    Can J Cardiol 21:783-7. 2005
    ..Several issues that decision-makers and providers may wish to consider when making such funding decisions are discussed...
  75. ncbi request reprint Early risk of stroke after transient ischemic attack: a systematic review and meta-analysis
    Caren M Wu
    Department of Medicine, University of Calgary, Calgary, AB, Canada
    Arch Intern Med 167:2417-22. 2007
    ....
  76. ncbi request reprint Prevalence of chronic kidney disease and survival among aboriginal people
    Song Gao
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, Alberta, Canada
    J Am Soc Nephrol 18:2953-9. 2007
    ....
  77. ncbi request reprint Meta-analysis: antibiotics for prophylaxis against hemodialysis catheter-related infections
    Matthew T James
    University of Calgary, Calgary, and University of Alberta and Institute of Health Economics, Edmonton, Alberta, Canada
    Ann Intern Med 148:596-605. 2008
    ..Catheter-related infections cause morbidity and mortality in patients undergoing hemodialysis...