Mortimer Mamelak

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint A pilot study on the effects of sodium oxybate on sleep architecture and daytime alertness in narcolepsy
    Mortimer Mamelak
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Sleep 27:1327-34. 2004
  2. doi request reprint Sporadic Alzheimer's disease: the starving brain
    Mortimer Mamelak
    Department of Psychiatry, University of Toronto and Baycrest Centre, Toronto, ON, Canada
    J Alzheimers Dis 31:459-74. 2012
  3. ncbi request reprint Alzheimer' s disease, oxidative stress and gammahydroxybutyrate
    Mortimer Mamelak
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Neurobiol Aging 28:1340-60. 2007
  4. doi request reprint Narcolepsy and depression and the neurobiology of gammahydroxybutyrate
    Mortimer Mamelak
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Prog Neurobiol 89:193-219. 2009

Detail Information

Publications4

  1. ncbi request reprint A pilot study on the effects of sodium oxybate on sleep architecture and daytime alertness in narcolepsy
    Mortimer Mamelak
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Sleep 27:1327-34. 2004
    ..To measure the effect of nocturnal sodium oxybate administration on sleep architecture in patients with narcolepsy...
  2. doi request reprint Sporadic Alzheimer's disease: the starving brain
    Mortimer Mamelak
    Department of Psychiatry, University of Toronto and Baycrest Centre, Toronto, ON, Canada
    J Alzheimers Dis 31:459-74. 2012
    ..Evidence is presented that gammahydroxybutyrate, a natural product of the GABA shunt, can provide the necessary energy, carbon, and antioxidant power and that its use may be able to delay the onset and progress of Alzheimer's disease...
  3. ncbi request reprint Alzheimer' s disease, oxidative stress and gammahydroxybutyrate
    Mortimer Mamelak
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Neurobiol Aging 28:1340-60. 2007
    ..It may therefore be possible to utilize GHB to strengthen the brain's innate defences against the pathological processes operating in the Alzheimer brain and, in this way, stem the advance of Alzheimer's disease...
  4. doi request reprint Narcolepsy and depression and the neurobiology of gammahydroxybutyrate
    Mortimer Mamelak
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Prog Neurobiol 89:193-219. 2009
    ..As such, the repeated use of GHB at night and the stabilization of sleep over time makes GHB an effective treatment for narcolepsy and a potentially effective treatment for depression...