Nikolai Malykhin

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. doi request reprint Fronto-limbic volumetric changes in major depressive disorder
    Nikolai V Malykhin
    Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
    J Affect Disord 136:1104-13. 2012
  2. doi request reprint In vivo quantification of hippocampal subfields using 4.7 T fast spin echo imaging
    N V Malykhin
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Neuroimage 49:1224-30. 2010
  3. doi request reprint Structural organization of the prefrontal white matter pathways in the adult and aging brain measured by diffusion tensor imaging
    Nikolai Malykhin
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2V2, Canada
    Brain Struct Funct 216:417-31. 2011
  4. pmc Structural changes in the hippocampus in major depressive disorder: contributions of disease and treatment
    Nikolai V Malykhin
    Department of Psychiatry, and Centre for Neuroscience, University of Alberta, Edmonton, Alta
    J Psychiatry Neurosci 35:337-43. 2010
  5. doi request reprint Aging hippocampus and amygdala
    Nikolai V Malykhin
    Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
    Neuroreport 19:543-7. 2008
  6. doi request reprint Diffusion tensor imaging tractography and reliability analysis for limbic and paralimbic white matter tracts
    Nikolai Malykhin
    Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
    Psychiatry Res 164:132-42. 2008
  7. doi request reprint Intact limbic-prefrontal connections and reduced amygdala volumes in Parkinson's disease with mild depressive symptoms
    Ian Surdhar
    Centre for Neuroscience, University of Alberta, Edmonton, Canada
    Parkinsonism Relat Disord 18:809-13. 2012
  8. ncbi request reprint Proton spectral editing for discrimination of lactate and threonine 1.31 ppm resonances in human brain in vivo
    Changho Choi
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Magn Reson Med 56:660-5. 2006
  9. doi request reprint Selective effects of aging on brain white matter microstructure: a diffusion tensor imaging tractography study
    Stijn Michielse
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Neuroimage 52:1190-201. 2010
  10. ncbi request reprint Age and dementia-associated atrophy predominates in the hippocampal head and amygdala in Parkinson's disease
    Thomas P Bouchard
    Department of Medicine Neurology, University of Alberta, 10230, 111th Avenue, Edmonton, Alberta, Canada
    Neurobiol Aging 29:1027-39. 2008

Collaborators

Detail Information

Publications12

  1. doi request reprint Fronto-limbic volumetric changes in major depressive disorder
    Nikolai V Malykhin
    Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
    J Affect Disord 136:1104-13. 2012
    ..The present structural MRI study aimed to determine the relationship between amygdala, cingulate and subgenual prefrontal cortex volumes in MDD and their associations with child abuse and antidepressants...
  2. doi request reprint In vivo quantification of hippocampal subfields using 4.7 T fast spin echo imaging
    N V Malykhin
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Neuroimage 49:1224-30. 2010
    ....
  3. doi request reprint Structural organization of the prefrontal white matter pathways in the adult and aging brain measured by diffusion tensor imaging
    Nikolai Malykhin
    Department of Biomedical Engineering, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2V2, Canada
    Brain Struct Funct 216:417-31. 2011
    ..The results of our study demonstrate regional age-related changes in the prefrontal white matter tracts of the human brain. This study was cross-sectional and therefore additional longitudinal studies are needed to confirm our findings...
  4. pmc Structural changes in the hippocampus in major depressive disorder: contributions of disease and treatment
    Nikolai V Malykhin
    Department of Psychiatry, and Centre for Neuroscience, University of Alberta, Edmonton, Alta
    J Psychiatry Neurosci 35:337-43. 2010
    ..Recent structural MRI studies have addressed the question of whether changes in the volume of hippocampal subregions may be associated with MDD...
  5. doi request reprint Aging hippocampus and amygdala
    Nikolai V Malykhin
    Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
    Neuroreport 19:543-7. 2008
    ....
  6. doi request reprint Diffusion tensor imaging tractography and reliability analysis for limbic and paralimbic white matter tracts
    Nikolai Malykhin
    Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
    Psychiatry Res 164:132-42. 2008
    ..97 (0.99), ventromedial prefrontal white matter 0.92 (0.93), crus of fornix 0.80 (0.81). The reported DTI protocol provides a reliable method to analyze limbic and paralimbic white matter tracts relevant to psychiatric disorders...
  7. doi request reprint Intact limbic-prefrontal connections and reduced amygdala volumes in Parkinson's disease with mild depressive symptoms
    Ian Surdhar
    Centre for Neuroscience, University of Alberta, Edmonton, Canada
    Parkinsonism Relat Disord 18:809-13. 2012
    ..Depression is very common in Parkinson's disease (PD). The neuropathological basis for this remains unclear; however, dysfunction in prefrontal and limbic regions may play a role...
  8. ncbi request reprint Proton spectral editing for discrimination of lactate and threonine 1.31 ppm resonances in human brain in vivo
    Changho Choi
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Magn Reson Med 56:660-5. 2006
    ..Using the calculated yields, the concentrations of Lac and Thr in the human occipital cortex were estimated to be 0.47+/-0.07 and 0.56+/-0.06 mM (mean+/-SD, N=7), respectively, with reference to Cr at 8 mM...
  9. doi request reprint Selective effects of aging on brain white matter microstructure: a diffusion tensor imaging tractography study
    Stijn Michielse
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Neuroimage 52:1190-201. 2010
    ..This study was cross-sectional, and therefore, additional longitudinal studies are needed to confirm our findings...
  10. ncbi request reprint Age and dementia-associated atrophy predominates in the hippocampal head and amygdala in Parkinson's disease
    Thomas P Bouchard
    Department of Medicine Neurology, University of Alberta, 10230, 111th Avenue, Edmonton, Alberta, Canada
    Neurobiol Aging 29:1027-39. 2008
    ..35, p=0.02); AG volumes correlated with CVLT-II recall (r=0.35, p=0.02). No correlations were found in non-PD (p>0.4). In conclusion, functionally meaningful age-associated hippocampal and amygdala atrophy occurs in PD...
  11. ncbi request reprint Measurement of brain glutamate and glutamine by spectrally-selective refocusing at 3 Tesla
    Changho Choi
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Magn Reson Med 55:997-1005. 2006
    ..The concentrations of Glu and Gln in the prefrontal cortex were estimated to be 9.7+/-0.5 and 3.0+/-0.7 mM (mean+/-SD, N=7), with reference to Cr at 8 mM...
  12. ncbi request reprint Detection of the myo-inositol 4.06-ppm resonance by selective J rewinding: application to human prefrontal cortex in vivo
    Changho Choi
    Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
    Magn Reson Med 54:1536-40. 2005
    ..The myo-inositol concentration in human prefrontal cortex is estimated to be 5.7 +/- 0.9 mumol/g (mean +/- SD, n = 7), with reference to NAA at 10 micromol/g...