Scott A Mabury

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. pmc Exploring indirect sources of human exposure to perfluoroalkyl carboxylates (PFCAs): evaluating uptake, elimination, and biotransformation of polyfluoroalkyl phosphate esters (PAPs) in the rat
    Jessica C D'eon
    Department of Chemistry, University of Toronto, Ontario, Canada
    Environ Health Perspect 119:344-50. 2011
  2. doi request reprint Biodegradation of polyfluoroalkyl phosphates as a source of perfluorinated acids to the environment
    Holly Lee
    Department of Chemistry, University of Toronto, Toronto, Ontario, Canada
    Environ Sci Technol 44:3305-10. 2010
  3. doi request reprint Atmospheric chemistry of 4:2 fluorotelomer iodide (n-C4F9CH2CH2I): kinetics and products of photolysis and reaction with OH radicals and Cl atoms
    Cora J Young
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6
    J Phys Chem A 112:13542-8. 2008
  4. doi request reprint Distribution of perfluorocarboxylate isomers in select samples from the North American environment
    Amila O De Silva
    University of Toronto, Department of Chemistry, Toronto, Ontario, Canada
    Environ Toxicol Chem 28:1801-14. 2009
  5. ncbi request reprint Spatial trends of perfluoroalkyl compounds in ringed seals (Phoca hispida) from the Canadian Arctic
    Craig M Butt
    Department of Chemistry, University of Toronto, Toronto, Ontario, Canada
    Environ Toxicol Chem 27:542-53. 2008
  6. ncbi request reprint Observation of a commercial fluorinated material, the polyfluoroalkyl phosphoric acid diesters, in human sera, wastewater treatment plant sludge, and paper fibers
    Jessica C D'eon
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 43:4589-94. 2009
  7. doi request reprint Perfluorinated phosphonic acids in Canadian surface waters and wastewater treatment plant effluent: discovery of a new class of perfluorinated acids
    Jessica C D'eon
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 28:2101-7. 2009
  8. ncbi request reprint Prevalence of long-chained perfluorinated carboxylates in seabirds from the Canadian Arctic between 1975 and 2004
    Craig M Butt
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 41:3521-8. 2007
  9. ncbi request reprint Perfluoroalkyl contaminants in a food web from Lake Ontario
    Jonathan W Martin
    Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 38:5379-85. 2004
  10. ncbi request reprint Atmospheric chemistry of N-methyl perfluorobutane sulfonamidoethanol, C4F9SO2N(CH3)CH2CH2OH: kinetics and mechanism of reaction with OH
    Jessica C D'eon
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada
    Environ Sci Technol 40:1862-8. 2006

Collaborators

Detail Information

Publications75

  1. pmc Exploring indirect sources of human exposure to perfluoroalkyl carboxylates (PFCAs): evaluating uptake, elimination, and biotransformation of polyfluoroalkyl phosphate esters (PAPs) in the rat
    Jessica C D'eon
    Department of Chemistry, University of Toronto, Ontario, Canada
    Environ Health Perspect 119:344-50. 2011
    ..Biotransformation of the polyfluoroalkyl phosphate esters (PAPs) is a possible source of PFCA exposure, because PAPs are used in food-contact paper packaging and have been observed in human sera...
  2. doi request reprint Biodegradation of polyfluoroalkyl phosphates as a source of perfluorinated acids to the environment
    Holly Lee
    Department of Chemistry, University of Toronto, Toronto, Ontario, Canada
    Environ Sci Technol 44:3305-10. 2010
    ..This observation, together with the diPAP concentrations observed in WWTP sludge, suggest PAPs-containing commercial products may be a significant contributor to the increased PFCA mass flows observed in WWTP effluents...
  3. doi request reprint Atmospheric chemistry of 4:2 fluorotelomer iodide (n-C4F9CH2CH2I): kinetics and products of photolysis and reaction with OH radicals and Cl atoms
    Cora J Young
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6
    J Phys Chem A 112:13542-8. 2008
    ..A mechanism for the atmospheric oxidation of fluorotelomer iodides, (C(x)F(2x+1)CH(2)CH(2)I, where x = 2, 4, 6,...) is proposed. Atmospheric oxidation of fluorotelomer iodides is a potential source of perfluorocarboxylic acids...
  4. doi request reprint Distribution of perfluorocarboxylate isomers in select samples from the North American environment
    Amila O De Silva
    University of Toronto, Department of Chemistry, Toronto, Ontario, Canada
    Environ Toxicol Chem 28:1801-14. 2009
    ..The presence of longer-chain isopropyl isomers may be preliminary evidence of isopropyl fluorinated organic precursors...
  5. ncbi request reprint Spatial trends of perfluoroalkyl compounds in ringed seals (Phoca hispida) from the Canadian Arctic
    Craig M Butt
    Department of Chemistry, University of Toronto, Toronto, Ontario, Canada
    Environ Toxicol Chem 27:542-53. 2008
    ..After adjusting for delta13C values, concentrations of most PFCs generally were statistically greater in the Grise Fiord, Qikiqtarjuaq, Arviat, and Nain populations...
  6. ncbi request reprint Observation of a commercial fluorinated material, the polyfluoroalkyl phosphoric acid diesters, in human sera, wastewater treatment plant sludge, and paper fibers
    Jessica C D'eon
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 43:4589-94. 2009
    ..DiPAPs were observed in paper fiber extracts at concentrations ranging from 34 +/- 30 to 2200 +/- 400 ng/g. The high diPAP concentrations in WWTP sludge suggest PAP materials may be prevalent in our daily lives...
  7. doi request reprint Perfluorinated phosphonic acids in Canadian surface waters and wastewater treatment plant effluent: discovery of a new class of perfluorinated acids
    Jessica C D'eon
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 28:2101-7. 2009
    ....
  8. ncbi request reprint Prevalence of long-chained perfluorinated carboxylates in seabirds from the Canadian Arctic between 1975 and 2004
    Craig M Butt
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 41:3521-8. 2007
    ..Finally, the detection of the 8:2 and 10:2 FTUCAs in seabirds is suggestive of fluorotelomer alcohols as a source of some PFCAs...
  9. ncbi request reprint Perfluoroalkyl contaminants in a food web from Lake Ontario
    Jonathan W Martin
    Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 38:5379-85. 2004
    ....
  10. ncbi request reprint Atmospheric chemistry of N-methyl perfluorobutane sulfonamidoethanol, C4F9SO2N(CH3)CH2CH2OH: kinetics and mechanism of reaction with OH
    Jessica C D'eon
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada
    Environ Sci Technol 40:1862-8. 2006
    ....
  11. doi request reprint Atmospheric degradation of perfluoro-2-methyl-3-pentanone: photolysis, hydrolysis and hydration
    Derek A Jackson
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, ON, Canada M5S 3H6
    Environ Sci Technol 45:8030-6. 2011
    ..The atmospheric fate of PFMP seems to be direct photolysis which, under low NO(x) conditions, gives PFPrA in a small yield. PFMP degradation contributes to, but does not appear to be the major source of, PFPrA observed in rainwater...
  12. ncbi request reprint Organochlorine compounds in Lake Superior: chiral polychlorinated biphenyls and biotransformation in the aquatic food web
    Charles S Wong
    Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 38:84-92. 2004
    ..This result suggests that significant biotransformation may occur for metabolizable PCB congeners over the lifespan of these biota. This study highlights the potential of chiral analysis to study biotransformation processes in food webs...
  13. ncbi request reprint Perfluoroalkyl contaminants in the Canadian Arctic: evidence of atmospheric transport and local contamination
    Naomi L Stock
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 41:3529-36. 2007
    ..1 to 5.9 pg/m3). In addition, results of this study also indicate that local perfluoroalkyl contamination of Resolute Lake, which is located downstream of an airport wastewater input, has occurred...
  14. ncbi request reprint Temporal trends of perfluoroalkyl compounds with isomer analysis in lake trout from Lake Ontario (1979-2004)
    Vasile I Furdui
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, ON M5S 3H6
    Environ Sci Technol 42:4739-44. 2008
    ..However, the most recent samples, comprised almost exclusively of linear isomers, indicate that current PFCA sources to Lake Ontario result from the telomerization process of linear telogens...
  15. ncbi request reprint Isomer distribution of perfluorocarboxylates in human blood: potential correlation to source
    Amila O De Silva
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6
    Environ Sci Technol 40:2903-9. 2006
    ..Predominance of linear PFCA isomers and the [even PFCA] > [odd PFCA] concentration trend in blood is suggestive of additional input from a strictly linear perfluoroalkyl source...
  16. doi request reprint Assessing the structure-activity relationships of fluorotelomer unsaturated acids and aldehydes with glutathione. Reactivity of glutathione with fluorotelomer unsaturated acids and aldehydes
    Amy A Rand
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, ON, M5S 3H6, Canada
    Cell Biol Toxicol 28:115-24. 2012
    ..This is the first study to examine the relationship of FTUCAs and FTUALs with biological nucleophiles by quantifying their intrinsic reactivity...
  17. doi request reprint Atmospheric chemistry of 4:2 fluorotelomer acrylate [C4F9CH2CH2OC(O)CH=CH2]: kinetics, mechanisms, and products of chlorine-atom- and OH-radical-initiated oxidation
    Craig M Butt
    Department of Chemistry, 80 St George Street, University of Toronto, Toronto, Ontario, Canada M5S 3H6
    J Phys Chem A 113:3155-61. 2009
    ..The atmospheric oxidation of fluorotelomer acrylates is a potential source of perfluorinated carboxylic acids in remote locations...
  18. ncbi request reprint Poly and perfluorinated carboxylates in North American precipitation
    Brian F Scott
    Aquatic Ecosystem Protection Research Division, Environment Canada, 867 Lakeshore Road, Burlington, Ontario, Canada
    Environ Sci Technol 40:7167-74. 2006
    ..S. sites indicate highly populated urban areas in the New York to Washington corridor as the main sources of PFOA, although low PFOA levels associated with air masses coming off the Atlantic Ocean imply multiple sources...
  19. ncbi request reprint Atmospheric lifetime and global warming potential of a perfluoropolyether
    Cora J Young
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 40:2242-6. 2006
    ..PFPMIE was shown to have instantaneous radiative forcing of 0.65 W m(-2) ppb(-1), which corresponds to a global warming potential on a 100 year time scale of 9000 relative to CO2 and 1.95 relative to CFC-11...
  20. ncbi request reprint Rapid response of Arctic ringed seals to changes in perfluoroalkyl production
    Craig M Butt
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 41:42-9. 2007
    ..Further, the relatively short doubling times of the PFCAs and PFOS disappearance half-lives support the hypothesis of atmospheric transport as the main transport mechanism of PFCs to the arctic environment...
  21. ncbi request reprint Identification of long-chain perfluorinated acids in biota from the Canadian Arctic
    Jonathan W Martin
    Department of Chemistry, University of Toronto, 80 St George Street, Lash Miller Building, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 38:373-80. 2004
    ..Future studies should continue to monitor all fluorinated contaminants and examine the absolute and relative toxicities for this novel suite of PFCAs...
  22. doi request reprint Atmospheric oxidation of polyfluorinated amides: historical source of perfluorinated carboxylic acids to the environment
    Derek A Jackson
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, ON, Canada M5S 3H6
    Environ Sci Technol 47:4317-24. 2013
    ..These primary products react further to give perfluorocarboxylic acids (PFCAs) as detected by LC-MS/MS, suggesting that eight carbon PFAMs were a historical source of PFCAs to remote regions, including the Canadian Arctic...
  23. ncbi request reprint Analysis for perfluorocarboxylic acids/anions in surface waters and precipitation using GC--MS and analysis of PFOA from large-volume samples
    Brian F Scott
    Environment Canada, National Water Research Institute, Aquatic Ecosystem Protection, Research Branch, 867 Lakeshore Road, Burlington, Ontario, Canada, L7R 4A6
    Environ Sci Technol 40:6405-10. 2006
    ..01 ng/L. This method was applied to Lake Superior samples which produced good agreement for C6-C9 PFCAs between regular analysis (GC-MS) and the XAD-7 followed by GC-MS analysis...
  24. doi request reprint Elucidating the pathways of poly- and perfluorinated acid formation in rainbow trout
    Craig M Butt
    Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 44:4973-80. 2010
    ..Alternatively PFOA could be formed directly through the beta-oxidation of the 7:3 beta-keto acid...
  25. ncbi request reprint Isolating isomers of perfluorocarboxylates in polar bears (Ursus maritimus) from two geographical locations
    Amila O De Silva
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6
    Environ Sci Technol 38:6538-45. 2004
    ..However, in comparison to the amount of branched isomers in the ECF PFOA standard, such minor percentages of branched PFCAs may suggest additional input from an exclusively linear isomer source...
  26. ncbi request reprint Trace level determination of perfluorinated compounds in water by direct injection
    Vasile I Furdui
    University of Toronto, Department of Chemistry, 80 St George Street, Toronto, Ontario, Canada M5S 3H6
    Chemosphere 73:S24-30. 2008
    ..Both PFOS and PFOA were present at less than 10 ng l(-1) in all Great Lake samples. Higher levels were detected in tributaries of Lake Ontario and effluents from sewage treatment plants...
  27. ncbi request reprint Vapor pressures of the fluorinated telomer alcohols--limitations of estimation methods
    Naomi L Stock
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, M5S 3H6 Canada
    Environ Sci Technol 38:1693-9. 2004
    ..It appears likely that the unique molecular geometry of the FTOHs influences not only their vapor pressure but also other physical properties and hence environmental fate and dissemination...
  28. ncbi request reprint Perfluorinated acids in Arctic snow: new evidence for atmospheric formation
    Cora J Young
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6, CLF Chem Consulting, 28 Rue Edouard Olivier, Brussels, Belgium
    Environ Sci Technol 41:3455-61. 2007
    ..A decrease in PFOS concentrations through time was observed, suggesting a fast response to changes in production. These data suggest that atmospheric oxidation of volatile precursors is a primary source of PFAs to the Arctic...
  29. doi request reprint Covalent binding of fluorotelomer unsaturated aldehydes (FTUALs) and carboxylic acids (FTUCAs) to proteins
    Amy A Rand
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 47:1655-63. 2013
    ..1 (±3.0)% binding, and was statistically similar to the percent binding associated with 8:2 FTUAL exposure (p > 0.05), indicating that the binding of 8:2 FTUAL to proteins might be a primary fate in the biotransformation of 8:2 FTOH...
  30. doi request reprint Determining the molecular interactions of perfluorinated carboxylic acids with human sera and isolated human serum albumin using nuclear magnetic resonance spectroscopy
    Jessica C D'eon
    Department of Chemistry, University of Toronto, Toronto, Ontario, M5S 3H6 Canada
    Environ Toxicol Chem 29:1678-88. 2010
    ..Interactions between PFCAs and HSA may affect the pharmacokinetics and distribution of fatty acids and certain drugs in the human body and warrant further investigation...
  31. doi request reprint Biotransformation of the 8:2 fluorotelomer acrylate in rainbow trout. 1. In vivo dietary exposure
    Craig M Butt
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 29:2726-35. 2010
    ..The results of the current study demonstrated a scenario in which a biologically labile compound is biotransformed to terminal metabolites that are much more biologically persistent...
  32. ncbi request reprint Degradation of fluorotelomer alcohols: a likely atmospheric source of perfluorinated carboxylic acids
    David A Ellis
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6
    Environ Sci Technol 38:3316-21. 2004
    ..Such reactions are expected to occur during the atmospheric degradation of all polyfluorinated materials, necessitating a reexamination of the environmental fate and impact of this important class of industrial chemicals...
  33. doi request reprint Fate of fluorotelomer acids in a soil-water microcosm
    Anne L Myers
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 29:1689-95. 2010
    ..The observed reactivity and lability of these analytes may contribute to the low levels of FTCAs detected in environmental samples...
  34. ncbi request reprint Polyfluorinated telomer alcohols and sulfonamides in the North American troposphere
    Naomi L Stock
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 38:991-6. 2004
    ..The nonuniform nature of the spatial distribution of both polyfluorinated sulfonamides and FTOHs is indicative of the importance of point sources for the dissemination of these contaminants in the North American troposphere...
  35. doi request reprint Disposition of perfluorinated acid isomers in Sprague-Dawley rats; part 2: subchronic dose
    Amila O De Silva
    Department of Chemistry, University of Toronto, Ontario, Canada
    Environ Toxicol Chem 28:555-67. 2009
    ....
  36. doi request reprint Biotransformation of the 8:2 fluorotelomer acrylate in rainbow trout. 2. In vitro incubations with liver and stomach S9 fractions
    Craig M Butt
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 29:2736-41. 2010
    ..These trends demonstrate the potential for considerable extrahepatic metabolism of the 8:2 FTAc before uptake into the internal tissues, ultimately limiting the overall bioaccumulation...
  37. ncbi request reprint Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes
    Vasile I Furdui
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, M5S 3H6
    Environ Sci Technol 41:1554-9. 2007
    ..The 10:2 FTUCA was detected only in 9% of all samples (nd, 45 pg g(-1)). For those PFCs where we determined lake water concentrations, the highest log BAFs were calculated for PFOS (4.1), PFDA (3.9), and PFOSA (3.8)...
  38. ncbi request reprint Aquatic persistence of eight pharmaceuticals in a microcosm study
    Monica W Lam
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 23:1431-40. 2004
    ..Observed photoproducts of several of the pharmaceuticals remained photoreactive, which led to further degradation in irradiated surface waters...
  39. ncbi request reprint Enantiomer-specific accumulation of PCB atropisomers in the bowhead whale (Balaena mysticetus)
    Paul F Hoekstra
    Department of Environmental Biology, University of Guelph, Ontario, Canada
    Environ Sci Technol 36:1419-25. 2002
    ..Results suggest that enantioselective accumulation of PCB-91, 95, and 149 is influenced by PCB concentrations, age, and/or the modification of an uncharacterized stereoselective process (or processes) during sexual maturity...
  40. doi request reprint Part I. A temporal study of PFCAs and their precursors in human plasma from two German cities 1982-2009
    Leo W Y Yeung
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, M5S 3H6, ON, Canada
    Environ Sci Technol 47:3865-74. 2013
    ..The evidence suggests they have contributed to the continued presence of the longer chain PFCAs and perhaps contribute to the slow decline of PFOA...
  41. ncbi request reprint Production of perfluorinated carboxylic acids (PFCAs) from the biotransformation of polyfluoroalkyl phosphate surfactants (PAPS): exploring routes of human contamination
    Jessica C D'eon
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6
    Environ Sci Technol 41:4799-805. 2007
    ..Previous investigations have found that PAPS can migrate into food from paper packaging. Here we link ingestion of PAPS with in vivo production of perfluorinated acids...
  42. doi request reprint In vitro interactions of biological nucleophiles with fluorotelomer unsaturated acids and aldehydes: fate and consequences
    Amy A Rand
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 46:7398-406. 2012
    ..This is the first study to probe the reactivity of FTUALs and FTUCAs with nucleophiles other than glutathione, further elucidating possible FTUAL and FTUCA fate within biological systems...
  43. doi request reprint Dietary bioaccumulation of perfluorophosphonates and perfluorophosphinates in juvenile rainbow trout: evidence of metabolism of perfluorophosphinates
    Holly Lee
    Department of Chemistry, University of Toronto, 80 St George St, Toronto, Ontario, Canada M5S 3H6
    Environ Sci Technol 46:3489-97. 2012
    ..As was previously observed for PFCAs and PFSAs, none of the BMFs determined here for the PFPAs and PFPiAs were greater than one, which suggests PFAAs do not biomagnify from dietary exposure in juvenile rainbow trout...
  44. doi request reprint Is indirect exposure a significant contributor to the burden of perfluorinated acids observed in humans?
    Jessica C D'eon
    Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6 Canada
    Environ Sci Technol 45:7974-84. 2011
    ....
  45. doi request reprint Toxicokinetics of perfluorocarboxylate isomers in rainbow trout
    Amila O De Silva
    University of Toronto, Department of Chemistry, 80 Saint George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 28:330-7. 2009
    ..As such, the toxicokinetics of PFCA isomers at environmentally realistic levels may deviate from the results of the present study...
  46. ncbi request reprint Fluorotelomer alcohol biodegradation yields poly- and perfluorinated acids
    Mary Joyce A Dinglasan
    Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto, Ontario, Canada M5S 3H6
    Environ Sci Technol 38:2857-64. 2004
    ..Telomer alcohols were demonstrated to be potential sources of PFCAs as a consequence of biotic degradation. Biological transformation may be a major degradation pathway for fluorinated telomer alcohols in aquatic systems...
  47. ncbi request reprint Microcosm evaluation of the fate, toxicity, and risk to aquatic macrophytes from perfluorooctanoic acid (PFOA)
    Mark L Hanson
    Centre for Toxicology, Department of Environmental Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    Arch Environ Contam Toxicol 49:307-16. 2005
    ..were consistently > or = 23.9 mg/L PFOA. A risk assessment for these plant species estimated a negligible probability of toxicity being observed from PFOA exposure at current environmental concentrations...
  48. ncbi request reprint Fluorotelomer acids are more toxic than perfluorinated acids
    Michelle M MacDonald Phillips
    Department of Environmental Biology, University of Guelph, Edmund C Bovey Building, Guelph, Ontario, Canada
    Environ Sci Technol 41:7159-63. 2007
    ..Our data provide the first evidence that PFCA precursors are more toxic than the PFCAs themselves...
  49. doi request reprint Paint solvent to food additive: an environmental route of dehalogenation for 4-chlorobenzotrifluoride
    Cora J Young
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 27:2233-8. 2008
    ....
  50. doi request reprint Environmental properties of pentafluorosulfanyl compounds: physical properties and photodegradation
    Derek A Jackson
    Department of Chemistry, University of Toronto, Toronto, Ontario, Canada
    Environ Toxicol Chem 28:1866-73. 2009
    ..The present study provides the first evidence that pentafluorosulfanyl can degrade under mild, environmentally relevant conditions...
  51. ncbi request reprint Identification of the major sources contributing to PM2.5 observed in Toronto
    Patrick K H Lee
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, M5S 3H6, Canada
    Environ Sci Technol 37:4831-40. 2003
    ..This suggests that in the northeastern part of North America, there are physical and/or chemical processes that lead to close interaction between secondary organic and inorganic aerosols...
  52. ncbi request reprint Aqueous photochemical reaction kinetics and transformations of fluoxetine
    Monica W Lam
    Department of Chemistry, University of Toronto, Toronto, Ontario, Canada
    Environ Sci Technol 39:513-22. 2005
    ..Thus, this latter process could be important in the elimination of FLX in surface waters...
  53. doi request reprint Atmospheric perfluorinated acid precursors: chemistry, occurrence, and impacts
    Cora J Young
    Department of Chemistry, University of Toronto, Toronto, ON, M5S 3H6, Canada
    Rev Environ Contam Toxicol 208:1-109. 2010
    ..It is clear that atmospheric oxidation of volatile precursors contributes to the overall burden of PFAs, though the extent to which this occurs is compound and environment dependent and is difficult to assess accurately...
  54. doi request reprint Uptake and elimination of perfluorinated phosphonic acids in the rat
    Jessica C D'eon
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6 Canada
    Environ Toxicol Chem 29:1319-29. 2010
    ..The biological fate of the mono-PFPAs and di-PFPAs determined here suggest there is the potential for human exposure and that if exposure does occur, they may be long-lived in the body...
  55. ncbi request reprint Enantiomeric composition of chiral polychlorinated biphenyl atropisomers in dated sediment cores
    Charles S Wong
    Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada
    Environ Toxicol Chem 26:254-63. 2007
    ..Thresholds for reductive dechlorination may exist, but they would be at concentrations of less than 30 to 80 microg/g...
  56. ncbi request reprint Biotransformation pathways of fluorotelomer-based polyfluoroalkyl substances: a review
    Craig M Butt
    Department of Chemistry, University of Toronto, Ontario, Canada
    Environ Toxicol Chem 33:243-67. 2014
    ..The PAPs compounds and 8:2 FTAC were shown to be direct precursors to FTOHs and thus follow similar degradation pathways...
  57. ncbi request reprint Analytical challenges hamper perfluoroalkyl research
    Jonathan W Martin
    University of Toronto, Canada
    Environ Sci Technol 38:248A-255A. 2004
  58. doi request reprint Perfluorinated carboxylic acids in directly fluorinated high-density polyethylene material
    Amy A Rand
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 45:8053-9. 2011
    ..The purpose of this study was to measure PFCAs in directly fluorinated material, serving as a previously unidentified source contributing to the environmental load of PFCAs, with potential for human exposure...
  59. ncbi request reprint Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada
    Jules C Carlson
    Lash Miller Chemical Laboratories, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 25:1-10. 2006
    ..These antibiotics are therefore expected to degrade primarily in agricultural soils before moving to greater depths or to groundwater in significant concentrations in most agricultural systems...
  60. ncbi request reprint Measurement of 13C/12C of chloroacetic acids by gas chromatography/combustion/isotope ratio mass spectrometry
    Charles S Wong
    Department of Chemistry, University of Toronto, 80 St George St, Ont, M5S 3H6, Toronto, Canada
    Chemosphere 50:903-9. 2003
    ..Our results underscore the potential of stable isotopes to serve as tracers of environmental sources of CAAs...
  61. ncbi request reprint Aqueous photolysis of 8:2 fluorotelomer alcohol
    Suzanne A Gauthier
    Department of Chemistry, University of Toronto, 80 St George St, Toronto, Ontario M5S 3H6, Canada
    Environ Toxicol Chem 24:1837-46. 2005
    ..The intermediates, 8:2 FTCA and 8:2 FTUCA, were photodegraded to verify the degradation pathway, and a mechanism for the photolysis was proposed whereby the end products of the photolysis pathway were PFOA (major) and PFNA (minor)...
  62. ncbi request reprint Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus mykiss)
    Jonathan W Martin
    University of Guelph, Department of Environmental Biology, Bovey Building, Guelph, Ontario N1G 2W1, Canada
    Environ Toxicol Chem 22:196-204. 2003
    ....
  63. ncbi request reprint Dietary accumulation of perfluorinated acids in juvenile rainbow trout (Oncorhynchus mykiss)
    Jonathan W Martin
    University of Guelph, Department of Environmental Biology, Bovey Building, Guelph, Ontario N1G 2W1, Canada
    Environ Toxicol Chem 22:189-95. 2003
    ..Dietary exposure will not result in biomagnification of PFAs in juvenile trout, but extrapolation of these bioaccumulation parameters to larger fish and homeothermic organisms should not be performed...
  64. ncbi request reprint Airborne haloacetic acids
    Jonathan W Martin
    Department of Environmental Biology, University of Guelph, Bovey Building, Guelph, Ontario, Canada N1G 2W1
    Environ Sci Technol 37:2889-97. 2003
    ..A simple deposition model indicated that dry deposition of TFA and TCA should not be neglected in temperate mid-latitude environments and that precipitation concentrations can be successfully predicted by the Henry's law constant...
  65. ncbi request reprint Rainbow trout (Oncorhynchus mykiss) can eliminate chiral organochlorine compounds enantioselectively
    Charles S Wong
    Department of Chemistry, University of Toronto, Ontario, Canada
    Environ Sci Technol 36:1257-62. 2002
    ..This study highlights the potential of chiral analysis as a tracer of in vivo biotransformation processes of xenobiotic compounds...
  66. doi request reprint Part II. A temporal study of PFOS and its precursors in human plasma from two German cities in 1982-2009
    Leo W Y Yeung
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, M5S 3H6, ON, Canada
    Environ Sci Technol 47:3875-82. 2013
    ..Our detection of di-SAmPAP is the first confirmation of human exposure to this commercially available product which is a plausible source of PFOS in humans...
  67. doi request reprint Enzymatic kinetic parameters for polyfluorinated alkyl phosphate hydrolysis by alkaline phosphatase
    Derek A Jackson
    Department of Chemistry, University of Toronto, Toronto, Ontario, Canada
    Environ Toxicol Chem 31:1966-71. 2012
    ..The results were used in a simple model to suggest that monoPAPs in a typical mammalian digestive tract would hydrolyze in approximately 100 s, supporting a previous study that showed its absence after a dosing study in rats...
  68. doi request reprint Analysis of mixed halogenated dibenzo-p-dioxins and dibenzofurans (PXDD/PXDFs) in soil by gas chromatography tandem mass spectrometry (GC-MS/MS)
    Anne L Myers
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada
    Chemosphere 87:1063-9. 2012
    ..Higher levels of polybrominated PXDD/PXDFs may indicate a significant bromine source was present during combustion...
  69. ncbi request reprint Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatocytes
    Jonathan W Martin
    Graduate Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ont, Canada M5S 2S2
    Chem Biol Interact 155:165-80. 2005
    ..Preincubation with aminobenzotriazole, but not pyrazole, inhibited the formation of metabolites from all FTOHs, suggesting that their oxidation was catalyzed by P450, not alcohol dehydrogenase...
  70. ncbi request reprint Effect of iron type on kinetics and carbon isotopic enrichment of chlorinated ethylenes during abiotic reduction on Fe(0)
    Nancy A VanStone
    Department of Chemistry, University of Toronto, 80 St George St, Toronto, Ontario, Canada M5S 3H6
    Ground Water 42:268-76. 2004
    ....
  71. doi request reprint A pilot survey of legacy and current commercial fluorinated chemicals in human sera from United States donors in 2009
    Holly Lee
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada, M5S 3H6
    Environ Sci Technol 45:8067-74. 2011
    ..PFPiAs were detected for the first time in human sera, with C6/C6 and C6/C8 PFPiAs as the dominant congeners, observed in >50% of the samples...
  72. ncbi request reprint Monitoring perfluorinated surfactants in biota and surface water samples following an accidental release of fire-fighting foam into Etobicoke Creek
    Cheryl A Moody
    Department of Chemistry, University of Toronto, Ontario, Canada
    Environ Sci Technol 36:545-51. 2002
    ..The residence time of perfluorooctanesulfonate in Etobicoke Creek as well as the high bioaccumulation in fish liver suggests that perfluorinated surfactants will persist and bioaccumulate following release into the aquatic environment...
  73. ncbi request reprint Significant residual fluorinated alcohols present in various fluorinated materials
    Mary Joyce A Dinglasan-Panlilio
    Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 40:1447-53. 2006
    ..This study suggests that elimination or reduction of these residual alcohols from all marketed fluorinated polymers and fluorosurfactants is key in reducing the prevalence of perfluorinated acids formed in the environment...
  74. ncbi request reprint Sampling atmospheric carbonaceous aerosols using an integrated organic gas and particle sampler
    Xinghua Fan
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada
    Environ Sci Technol 37:3145-51. 2003
    ..These data illustrate the utility of an IOGAPS system to more accurately determine the particle-bound OC in comparison to FP-based systems...
  75. ncbi request reprint PhetoFate: a new approach in accounting for the contribution of indirect photolysis of pesticides and pharmaceuticals in surface waters
    Monica W Lam
    Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada, M5S 3H6
    Environ Sci Technol 37:899-907. 2003
    ..However, in low nitrate waters, the contribution of cDOM-derived reactive intermediates to the degradation of parent compounds became more apparent..