Larry D Lynd

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. pmc Exploring patients' perceptions for insulin therapy in type 2 diabetes: a Brazilian and Canadian qualitative study
    Camila Guimarães
    University of Sao Paulo, Brazil
    Patient Prefer Adherence 4:171-9. 2010
  2. pmc A discrete choice experiment evaluation of patients' preferences for different risk, benefit, and delivery attributes of insulin therapy for diabetes management
    Camila Guimarães
    University of Sao Paulo, Brazil
    Patient Prefer Adherence 4:433-40. 2010
  3. pmc Economic burden of asthma: a systematic review
    Katayoun Bahadori
    Centre for Clinical Epidemiology and Evaluation C2E2, UBC, Vancouver, BC, Canada
    BMC Pulm Med 9:24. 2009
  4. ncbi request reprint A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Can J Clin Pharmacol 14:e215-26. 2007
  5. ncbi request reprint Antiviral agents for influenza: a comparison of cost-effectiveness data
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
    Pharmacoeconomics 23:1083-106. 2005
  6. pmc Prescription to over-the-counter deregulation in Canada: are we ready for it, or do we need to be?
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia and the Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, Vancouver, BC
    CMAJ 173:775-7. 2005
  7. ncbi request reprint A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Can J Clin Pharmacol 14:e215-26. 2007
  8. ncbi request reprint A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Can J Clin Pharmacol 14:e215-26. 2007
  9. pmc An evaluation of the osmole gap as a screening test for toxic alcohol poisoning
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    BMC Emerg Med 8:5. 2008
  10. ncbi request reprint Using the incremental net benefit framework for quantitative benefit-risk analysis in regulatory decision-making--a case study of alosetron in irritable bowel syndrome
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Value Health 13:411-7. 2010

Collaborators

Detail Information

Publications43

  1. pmc Exploring patients' perceptions for insulin therapy in type 2 diabetes: a Brazilian and Canadian qualitative study
    Camila Guimarães
    University of Sao Paulo, Brazil
    Patient Prefer Adherence 4:171-9. 2010
    ..To explore which attributes of insulin therapy drive patients' preferences for management in Canada and Brazil...
  2. pmc A discrete choice experiment evaluation of patients' preferences for different risk, benefit, and delivery attributes of insulin therapy for diabetes management
    Camila Guimarães
    University of Sao Paulo, Brazil
    Patient Prefer Adherence 4:433-40. 2010
    ..To evaluate patients' preferences for various attributes of insulin treatment, including route of insulin delivery...
  3. pmc Economic burden of asthma: a systematic review
    Katayoun Bahadori
    Centre for Clinical Epidemiology and Evaluation C2E2, UBC, Vancouver, BC, Canada
    BMC Pulm Med 9:24. 2009
    ..It is also associated with the loss of future potential earnings related to both morbidity and mortality. The objective of the study is to determine the burden of disease costs associated with asthma...
  4. ncbi request reprint A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Can J Clin Pharmacol 14:e215-26. 2007
    ..g. enoxaparin) as thromboprophylaxis for the prevention of deep vein thrombosis (DVT)...
  5. ncbi request reprint Antiviral agents for influenza: a comparison of cost-effectiveness data
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
    Pharmacoeconomics 23:1083-106. 2005
    ....
  6. pmc Prescription to over-the-counter deregulation in Canada: are we ready for it, or do we need to be?
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia and the Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, Vancouver, BC
    CMAJ 173:775-7. 2005
  7. ncbi request reprint A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Can J Clin Pharmacol 14:e215-26. 2007
    ..g. enoxaparin) as thromboprophylaxis for the prevention of deep vein thrombosis (DVT)...
  8. ncbi request reprint A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Can J Clin Pharmacol 14:e215-26. 2007
    ..g. enoxaparin) as thromboprophylaxis for the prevention of deep vein thrombosis (DVT)...
  9. pmc An evaluation of the osmole gap as a screening test for toxic alcohol poisoning
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    BMC Emerg Med 8:5. 2008
    ....
  10. ncbi request reprint Using the incremental net benefit framework for quantitative benefit-risk analysis in regulatory decision-making--a case study of alosetron in irritable bowel syndrome
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Value Health 13:411-7. 2010
    ....
  11. doi request reprint Socioeconomic differences in preferences and willingness-to-pay for insulin delivery systems in type 1 and type 2 diabetes
    Camila Guimarães
    University of Sao Paulo, Sao Paulo, Brazil
    Diabetes Technol Ther 11:567-73. 2009
    ..The aim of this study was to investigate the association between socioeconomic status (SES) and patients' preferences and willingness to pay (WTP) for various attributes of insulin administration for diabetes management...
  12. doi request reprint Risk of gastrointestinal events in patients with rheumatoid arthritis after withdrawal of rofecoxib
    Carlo A Marra
    Faculty of Pharmaceutical Sciences, University of British Columbia UBC, Vancouver, Canada
    J Rheumatol 39:910-5. 2012
    ..To examine the incidence of gastrointestinal (GI) events in patients with rheumatoid arthritis (RA) after the removal of rofecoxib from the market...
  13. ncbi request reprint Responsiveness of health state utility values in knee osteoarthritis
    Erin M Davis
    From the School of Pharmacy, Memorial University, St John s, Newfoundland and Labrador Collaboration for Outcomes Research and Evaluation CORE, and School of Population and Public Health, University of British Columbia, Arthritis Research Centre, and Centre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute, Vancouver, British Columbia, Canada
    J Rheumatol 40:2075-82. 2013
    ..Therefore, we examined the responsiveness of the Health Utilities Index mark 3 (HUI3) and Paper Adaptive Test-5D (PAT-5DQOL) in a group of patients with knee OA...
  14. pmc Cost-effectiveness of self-managed versus physician-managed oral anticoagulation therapy
    Dean A Regier
    Collaboration for Outcomes Research and Evaluation, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, BC
    CMAJ 174:1847-52. 2006
    ..We sought to compare the incremental cost and health benefits of self-management with those of physician management from the perspective of the Canadian health care payer over a 5-year period...
  15. ncbi request reprint An evaluation of patients' willingness to trade symptom-free days for asthma-related treatment risks: a discrete choice experiment
    Helen M McTaggart-Cowan
    Department of Health Care and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada
    J Asthma 45:630-8. 2008
    ..The objective of this study was to quantify these preferences, in terms of risk-benefits trade-offs, for six asthma treatment attributes using a discrete choice experiment (DCE)...
  16. pmc Agreement between aggregate and individual-level measures of income and education: a comparison across three patient groups
    Carlo A Marra
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    BMC Health Serv Res 11:69. 2011
    ..The purpose of this study was to determine the level of agreement between aggregate-level and individual-level measures of income and education among three distinct patient groups, specifically asthma, diabetes, and rheumatoid patients...
  17. pmc Effects of prescription adaptation by pharmacists
    Michael R Law
    Centre for Health Services and Policy Research, School of Population and Public Health, The University of British Columbia, 201 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada
    BMC Health Serv Res 10:313. 2010
    ..We hypothesize this policy increased drug utilization and drug costs, increased patient adherence to medication, and reduced total healthcare resource use...
  18. pmc Antibiotic consumption in children prior to diagnosis of asthma
    Fawziah Marra
    University of British Columbia, BC, Canada
    BMC Pulm Med 11:32. 2011
    ..Asthma is difficult to diagnose in children and at times misdiagnosis of an infection can occur. However, little is known about the magnitude and patterns of antibiotic consumption in children with asthma relative to those without asthma...
  19. ncbi request reprint The irrationality of the present use of the osmole gap: applicable physical chemistry principles and recommendations to improve the validity of current practices
    Yoshikata Koga
    Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada
    Toxicol Rev 23:203-11. 2004
    ..This correction should be applied before the evaluation of the osmolar gap as a screening test for other low molecular weight substances proceeds...
  20. ncbi request reprint Health economic evaluation: a primer for the practicing rheumatologist
    Michael C Y Tan
    Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada
    Arthritis Rheum 55:648-56. 2006
  21. pmc Trends in asthma-related direct medical costs from 2002 to 2007 in British Columbia, Canada: a population based-cohort study
    Pierrick Bedouch
    Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 7:e50949. 2012
    ..The objective of this work was to analyze direct asthma-related medical costs, and trends in total and per-patient costs of hospitalizations, physician visits, and medications...
  22. doi request reprint Evaluating societal preferences for human papillomavirus vaccine and cervical smear test screening programme
    Bridgette Oteng
    Faculty of Pharmaceutical Sciences, University of British Columbia, 2146 East Mall, Vancouver V5Z163, British Columbia, Canada
    Sex Transm Infect 87:52-7. 2011
    ..Public preferences for HPV vaccines and smear test screening were determined using a discrete choice experiment...
  23. ncbi request reprint Antibiotic use in children is associated with increased risk of asthma
    Fawziah Marra
    University of British Columbia, Faculty of Pharmaceutical Sciences, Centre for Health Evaluation and Outcomes Sciences, St Paul s Hospital, 620 1081 Burrard St, Vancouver, British Columbia, Canada
    Pediatrics 123:1003-10. 2009
    ..Antibiotic exposure in early childhood is a possible contributor to the increasing asthma prevalence in industrialized countries. Although a number of published studies have tested this hypothesis, the results have been conflicting...
  24. ncbi request reprint Predicting response to day treatment for personality disorder
    John S Ogrodniczuk
    Department of Psychiatry, University of British Columbia, Vancouver, British Columbia
    Can J Psychiatry 56:110-7. 2011
    ..Efforts to improve the effectiveness of day treatment should attend to factors that influence treatment response. Our prospective study identified predictors of response to day treatment for personality disorder (PD)...
  25. doi request reprint Dispensation of long-acting β agonists with or without inhaled corticosteroids, and risk of asthma-related hospitalisation: a population-based study
    Mohsen Sadatsafavi
    Institute for Heart and Lung Health, Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada
    Thorax 69:328-34. 2014
    ....
  26. doi request reprint Pharmacists' preferences for providing patient-centered services: a discrete choice experiment to guide health policy
    Kelly A Grindrod
    University of British Columbia, Vancouver, Canada
    Ann Pharmacother 44:1554-64. 2010
    ..In Canada, most pharmacists are not paid to provide patient-centered services. In other areas of the world these services have suffered from poor adoption by pharmacists...
  27. ncbi request reprint Comparison of HRQL between unicompartmental knee arthroplasty and total knee arthroplasty for the treatment of osteoarthritis
    Katie Sweeney
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    J Arthroplasty 28:187-90. 2013
    ..Adjusting for age and gender, there was no significant difference between UKA and TKA in HRQL over the first 6 months following surgery...
  28. ncbi request reprint Approval process and access to prescription drugs in Canada
    Carlo A Marra
    University of British Columbia, Arthritis Research Centre of Canada, Centre for Clinical Epidemiology and Evaluation, 717 828 West 10th Avenue, Vancouver, British Columbia V5Z 1L8, Canada
    Arthritis Rheum 55:9-11. 2006
  29. doi request reprint Barriers to integrating personalized medicine into clinical practice: a best-worst scaling choice experiment
    Mehdi Najafzadeh
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    Genet Med 14:520-6. 2012
    ..The objective of this study was to elicit the preferences of physicians about regarding applying personalized medicine in their clinical practice as these strategies become available...
  30. ncbi request reprint The use of the osmole gap as a screening test for the presence of exogenous substances
    Roy A Purssell
    Division of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Toxicol Rev 23:189-202. 2004
    ....
  31. ncbi request reprint The validity of generic and condition-specific preference-based instruments: the ability to discriminate asthma control status
    Helen M McTaggart-Cowan
    Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, 7th Floor, 828 West 10th Avenue, Vancouver, BC, Canada, V5Z 1L8
    Qual Life Res 17:453-62. 2008
    ..The objective of this study was to evaluate the validity of generic and condition-specific preference-based instruments, in terms of their ability to distinguish asthma control...
  32. doi request reprint A quantitative evaluation of the regulatory assessment of the benefits and risks of rofecoxib relative to naproxen: an application of the incremental net-benefit framework
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Pharmacoepidemiol Drug Saf 19:1172-80. 2010
    ....
  33. pmc Genomic testing to determine drug response: measuring preferences of the public and patients using Discrete Choice Experiment (DCE)
    Mehdi Najafzadeh
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    BMC Health Serv Res 13:454. 2013
    ..e. sensitivity and specificity of the test), invasiveness of the testing procedure, test cost, and the probability and severity of side effects associated with treatment...
  34. doi request reprint Predictors of premature termination of day treatment for personality disorder
    John S Ogrodniczuk
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
    Psychother Psychosom 77:365-71. 2008
    ..Efforts to improve compliance should begin by recognising risk factors for premature termination. This prospective study identified predictors of premature termination from a day treatment program for personality disorder...
  35. doi request reprint Inadequate statistical power to detect clinically significant differences in adverse event rates in randomized controlled trials
    Ruth Tsang
    Vancouver General Hospital, Vancouver, British Columbia, Canada
    J Clin Epidemiol 62:609-16. 2009
    ..To determine the statistical power to detect potentially clinically significant differences in serious adverse events between drug therapies reported in a sample of randomized controlled trials (RCTs)...
  36. doi request reprint Randomized controlled trial evaluating pictogram augmentation of HIV medication information
    Kyle Wilby
    University of British Columbia, Vancouver, British Columbia, Canada
    Ann Pharmacother 45:1378-83. 2011
    ..The use of pictograms on medication vials as a means of improving patients' understanding of medication information has been shown to positively influence understanding and adherence compared to those using text alone...
  37. doi request reprint Patient preferences and experiences of CPAP and oral appliances for the treatment of obstructive sleep apnea: a qualitative analysis
    Fernanda R Almeida
    Oral Health Sciences, University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada, V6T 1Z3
    Sleep Breath 17:659-66. 2013
    ..The aim of this study is to better understand patients' perspectives and preferences about treatment with continuous positive airway pressure (CPAP) and oral appliance (OA) devices for obstructive sleep apnea...
  38. pmc The effects of long-acting bronchodilators on total mortality in patients with stable chronic obstructive pulmonary disease
    Agnes Kliber
    Department of Medicine Respiratory Division, University of British Columbia, 6040 Iona Drive, Vancouver, V6T 2E8, Canada
    Respir Res 11:56. 2010
    ..We performed a comprehensive systematic review and meta-analysis to evaluate the effects of long-acting bronchodilators on total mortality in stable COPD...
  39. ncbi request reprint Using administrative healthcare data to recruit study subjects: experience with 'camouflaged sampling'
    Larry D Lynd
    Department of Health Care and Epidemiology, Faculty of Medicine University of British Columbia, Centre for Health Evaluation and Outcomes Sciences, Vancouver, BC, Canada
    Eur J Epidemiol 19:517-25. 2004
    ..To recruit a sample of asthmatics heterogeneous for short-acting (SA) beta-agonist use while protecting their privacy, and to compare participants recruited via 'camouflaged sampling' to those recruited through media advertising...
  40. ncbi request reprint Patterns of inhaled asthma medication use: a 3-year longitudinal analysis of prescription claims data from British Columbia, Canada
    Larry D Lynd
    Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada V6Z 1Y6
    Chest 122:1973-81. 2002
    ..To assess trends in asthma management and to identify factors associated with increasing short-acting (SA) beta-agonist utilization in British Columbia using administrative prescription data...
  41. ncbi request reprint Reconcilable differences: a cross-sectional study of the relationship between socioeconomic status and the magnitude of short-acting beta-agonist use in asthma
    Larry D Lynd
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Chest 126:1161-8. 2004
    ..To assess the association between socioeconomic status (SES) and short-acting (SA) beta-agonist use, controlling for asthma severity...
  42. ncbi request reprint Advances in risk-benefit evaluation using probabilistic simulation methods: an application to the prophylaxis of deep vein thrombosis
    Larry D Lynd
    Centre for Evaluation of Medicines, St Joseph s Hospital, Hamilton, Ontario, Canada
    J Clin Epidemiol 57:795-803. 2004
    ..Published data are used to introduce the risk-benefit acceptability curve as a novel method of illustrating risk-benefit analysis...
  43. ncbi request reprint Cost-effectiveness of the implantable cardioverter defibrillator: a review of current evidence
    Larry D Lynd
    Centre for Evaluation of Medicines, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Cardiovasc Electrophysiol 14:S99-103. 2003
    ..The high relative cost of therapy with the ICD versus antiarrhythmic drugs has raised questions regarding its cost-effectiveness. To address these questions, we review the literature on ICD cost-effectiveness...