Doerte Luensmann

Summary

Affiliation: University of Waterloo
Country: Canada

Publications

  1. ncbi request reprint Localization of lysozyme sorption to conventional and silicone hydrogel contact lenses using confocal microscopy
    Doerte Luensmann
    Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 34:683-97. 2009
  2. doi request reprint Protein deposition on contact lenses: the past, the present, and the future
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada
    Cont Lens Anterior Eye 35:53-64. 2012
  3. doi request reprint Corneal staining and cell shedding during the development of solution-induced corneal staining
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada
    Optom Vis Sci 89:868-74. 2012
  4. ncbi request reprint Confocal microscopy and albumin penetration into contact lenses
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 84:839-47. 2007
  5. doi request reprint Impact of fluorescent probes on albumin sorption profiles to ophthalmic biomaterials
    Doerte Luensmann
    School of Optometry, Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario N2L3G1, Canada
    J Biomed Mater Res B Appl Biomater 94:327-36. 2010
  6. pmc The efficiency of contact lens care regimens on protein removal from hydrogel and silicone hydrogel lenses
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, ON, Canada
    Mol Vis 16:79-92. 2010
  7. doi request reprint Determination of albumin sorption to intraocular lenses by radiolabeling and confocal laser scanning microscopy
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    J Cataract Refract Surg 35:2000-7. 2009
  8. pmc Composition of incubation solution impacts in vitro protein uptake to silicone hydrogel contact lenses
    Salsabeel Jadi
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
    Mol Vis 18:337-47. 2012
  9. doi request reprint Impact of tear film components on the conformational state of lysozyme deposited on contact lenses
    Alan Ng
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada
    J Biomed Mater Res B Appl Biomater 101:1172-81. 2013
  10. doi request reprint The effects of hyaluronic acid incorporated as a wetting agent on lysozyme denaturation in model contact lens materials
    Andrea Weeks
    School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada
    J Biomater Appl 28:323-33. 2013

Detail Information

Publications14

  1. ncbi request reprint Localization of lysozyme sorption to conventional and silicone hydrogel contact lenses using confocal microscopy
    Doerte Luensmann
    Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario, Canada
    Curr Eye Res 34:683-97. 2009
    ..To investigate the distribution profile of hen egg lysozyme (HEL) through poly-2-hydroxyethyl methacrylate (pHEMA)-based lens materials and silicone hydrogel (SH) lens materials using confocal laser scanning microscopy (CLSM)...
  2. doi request reprint Protein deposition on contact lenses: the past, the present, and the future
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada
    Cont Lens Anterior Eye 35:53-64. 2012
    ..Newer approaches incorporating phosphorylcholine, polyethers or hyaluronic acid into potential contact lens materials result in reduced protein deposition rates compared to current lens materials...
  3. doi request reprint Corneal staining and cell shedding during the development of solution-induced corneal staining
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada
    Optom Vis Sci 89:868-74. 2012
    ..Following the staining assessment, corneal cells were collected from the ocular surface using a non-contact irrigation system to determine ocular cell shedding rates...
  4. ncbi request reprint Confocal microscopy and albumin penetration into contact lenses
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 84:839-47. 2007
    ..To develop a novel in vitro method to detect the depth of penetration of the tear film protein albumin into contact lens materials using confocal laser scanning microscopy (CLSM)...
  5. doi request reprint Impact of fluorescent probes on albumin sorption profiles to ophthalmic biomaterials
    Doerte Luensmann
    School of Optometry, Centre for Contact Lens Research, University of Waterloo, Waterloo, Ontario N2L3G1, Canada
    J Biomed Mater Res B Appl Biomater 94:327-36. 2010
    ..BSA profiles to pHEMA-based and silicone hydrogel lenses were highly dependent on the fluorescent probe used and none of the probes accurately reflected quantitative protein levels for the lens materials investigated...
  6. pmc The efficiency of contact lens care regimens on protein removal from hydrogel and silicone hydrogel lenses
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, ON, Canada
    Mol Vis 16:79-92. 2010
    ....
  7. doi request reprint Determination of albumin sorption to intraocular lenses by radiolabeling and confocal laser scanning microscopy
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    J Cataract Refract Surg 35:2000-7. 2009
    ..To determine albumin adsorption profiles and penetration depth of 3 intraocular lens (IOL) materials over time using confocal laser scanning microscopy (CLSM) and radiolabeling...
  8. pmc Composition of incubation solution impacts in vitro protein uptake to silicone hydrogel contact lenses
    Salsabeel Jadi
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
    Mol Vis 18:337-47. 2012
    ..To determine the impact of incubation solution composition on protein deposition to silicone hydrogel (SH) contact lenses using a simplistic and a complex model of the tear film...
  9. doi request reprint Impact of tear film components on the conformational state of lysozyme deposited on contact lenses
    Alan Ng
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada
    J Biomed Mater Res B Appl Biomater 101:1172-81. 2013
    ..To investigate the impact of lactoferrin and lipids on the kinetic denaturation of lysozyme deposited on silicone and conventional hydrogel lenses, using a complex artificial tear solution (ATS)...
  10. doi request reprint The effects of hyaluronic acid incorporated as a wetting agent on lysozyme denaturation in model contact lens materials
    Andrea Weeks
    School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada
    J Biomater Appl 28:323-33. 2013
    ..The distribution of hyaluronic acid within hydrogels appears to affect denaturation, with more surface mobile, lower molecular weight hyaluronic acid being more effective in preventing denaturation...
  11. ncbi request reprint Optimization of a fluorescence-based lysozyme activity assay for contact lens studies
    Alan Ng
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada
    Curr Eye Res 38:252-9. 2013
    ....
  12. doi request reprint Albumin adsorption to contact lens materials: a review
    Doerte Luensmann
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, 200, University Avenue West, Waterloo, Ontario, N2L 3G1, Canada
    Cont Lens Anterior Eye 31:179-87. 2008
    ..This review paper summarizes the impact of individual material compositions, water content, hydrophobicity and electrostatic attraction on the adsorption behavior of the protein albumin...
  13. doi request reprint Impact of tear film components on lysozyme deposition to contact lenses
    Alan Ng
    Centre for Contact Lens Research, School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada
    Optom Vis Sci 89:392-400. 2012
    ..To investigate the impact of lactoferrin and lipids on the kinetic deposition of lysozyme on silicone and conventional hydrogel lenses, using a complex artificial tear solution (ATS)...
  14. doi request reprint Hyaluronic acid as an internal wetting agent in model DMAA/TRIS contact lenses
    Andrea Weeks
    School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada
    J Biomater Appl 27:423-32. 2012
    ..These results suggest that HA has great potential to be used as a wetting agent in silicone hydrogel contact lenses to improve wettability and to decrease lysozyme sorption and denaturation...