Research Topics
| Stephen G LomberSummaryAffiliation: University of Western Ontario Country: Canada Publications
Research Grants
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Detail Information
Publications
Double dissociation of 'what' and 'where' processing in auditory cortexStephen G Lomber
Centre for Brain and Mind, Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, Middlesex Road, London, Ontario N6A 5K8, Canada
Nat Neurosci 11:609-16. 2008..These findings support a model of cortical organization that proposes that identifying an acoustic stimulus ('what') and its spatial location ('where') are processed in separate streams in auditory cortex...
Acoustic motion processing in auditory cortexSTEPHEN LOMBER
The Brain and Mind Institute, The University of Western Ontario, London, Ontario, Canada
J Acoust Soc Am 131:3441. 2012..Supported by the Canadian Institutes of Health Research and the Natural Sciences and Engineering Research Council of Canada...- Functional specialization in non-primary auditory cortex of the cat: areal and laminar contributions to sound localizationStephen G Lomber
Centre for Brain and Mind, Department of Physiology and Pharmacology, University of Western Ontario, London, ON, Canada
Hear Res 229:31-45. 2007..Therefore, we propose that sound localization signals processed in primary and non-primary auditory cortex are transmitted to the superior colliculus by means of the auditory field of the AES... - Relocation of specific visual functions following damage of mature posterior parietal cortexStephen G Lomber
School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, TX 75080, USA
Prog Brain Res 157:157-72. 2006..Overall, this series of experiments demonstrates that certain visual functions may relocate to specific cortical loci following damage to discrete areas within posterior parietal cortex... - Restoration of acoustic orienting into a cortically deaf hemifield by reversible deactivation of the contralesional superior colliculus: the acoustic "Sprague Effect"Stephen G Lomber
Centre for Brain and Mind, Robarts Research Institute, University of Western Ontario, 100 Perth Drive, London, Ontario N6A 5K8, Canada
J Neurophysiol 97:979-93. 2007..Thus the "Sprague Effect" is not unique to a particular sensory system and deactivation of the contralesional SC can restore either visual or acoustic orienting responses into an impaired hemifield after cortical damage... - Cross-modal plasticity in specific auditory cortices underlies visual compensations in the deafStephen G Lomber
Centre for Brain and Mind, Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada
Nat Neurosci 13:1421-7. 2010.... - Adaptive crossmodal plasticity in deaf auditory cortex: areal and laminar contributions to supranormal vision in the deafStephen G Lomber
Department of Physiology and Pharmacology, Centre for Brain and Mind, The University of Western Ontario, London, Ontario, Canada
Prog Brain Res 191:251-70. 2011.... - Sound localization during homotopic and heterotopic bilateral cooling deactivation of primary and nonprimary auditory cortical areas in the catShveta Malhotra
School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, TX, USA
J Neurophysiol 97:26-43. 2007..Neither unilateral nor bilateral deactivation of AI/DZ, PAF, or AES affected the accurate localization of a visual target. The results suggest that hemispheric deactivations contribute independently to sound localization deficits... - Evidence for hierarchical processing in cat auditory cortex: nonreciprocal influence of primary auditory cortex on the posterior auditory fieldAndres Carrasco
Graduate Program in Neuroscience, University of Western Ontario, London, Ontario N6A 5B8, Canada
J Neurosci 29:14323-33. 2009..In comparison, we did not identify any significant changes in A1 neuronal responses during deactivation of PAF neurons. These findings support proposed models of hierarchal processing in cat auditory cortex... - Reciprocal modulatory influences between tonotopic and nontonotopic cortical fields in the catAndres Carrasco
Graduate Program in Neuroscience, University of Western Ontario, London, Ontario N6A 5B8, Canada
J Neurosci 30:1476-87. 2010.... - Sound localization deficits during reversible deactivation of primary auditory cortex and/or the dorsal zoneShveta Malhotra
Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada
J Neurophysiol 99:1628-42. 2008.... - Influence of core auditory cortical areas on acoustically evoked activity in contralateral primary auditory cortexAndres Carrasco
Brain and Mind Institute, Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A 5C1, Canada
J Neurosci 33:776-89. 2013..These findings demonstrate that during periods of acoustic exposure, callosal projections emanating from core auditory areas modulate A1 neuronal activity via excitatory inputs... - Cortical control of sound localization in the cat: unilateral cooling deactivation of 19 cerebral areasShveta Malhotra
Cerebral Systems Laboratory, School of Behavioral and Brain Sciences, The University of Texas at Dallas, 2601 N. Floyd Road, GR41, Richardson, TX 75080, USA
J Neurophysiol 92:1625-43. 2004..Overall, three regions in auditory cortex (AI, PAF, AES) are critical for accurate sound localization as assessed by orienting... - Neuronal activation times to simple, complex, and natural sounds in cat primary and nonprimary auditory cortexAndres Carrasco
Centre for Brain and Mind, Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
J Neurophysiol 106:1166-78. 2011..Collectively, these results demonstrate that acoustic signals, regardless of complexity, induce a directional pattern of activation in auditory cortex... - Cerebral areas mediating visual redirection of gaze: cooling deactivation of 15 loci in the catStephen G Lomber
Cerebral Systems Laboratory, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA
J Comp Neurol 474:190-208. 2004..These loci have several features in common with cortical fields in monkey and human brains that contribute to the visually guided redirection of the head and eyes... - Prefrontal cortex deactivation in macaques alters activity in the superior colliculus and impairs voluntary control of saccadesMichael J Koval
Graduate Program in Neuroscience, University of Western Ontario, London, Ontario N6A 3K7, Canada
J Neurosci 31:8659-68. 2011..The results suggest that the dlPFC participates in the cognitive control of gaze by suppressing stimulus-evoked automatic saccade programs... - Differential modulatory influences between primary auditory cortex and the anterior auditory fieldAndres Carrasco
Graduate Program in Neuroscience, University of Western Ontario, London, Ontario N6A 5B8, Canada
J Neurosci 29:8350-62. 2009..Collectively, these results suggest that the modulation of acoustic information between A1 and AAF in cat auditory cortex is dominated by a unidirectional AAF to A1 pathway... - Auditory cortex projections target the peripheral field representation of primary visual cortexAmee J Hall
Graduate Program in Neuroscience, University of Western Ontario, London, ON, Canada
Exp Brain Res 190:413-30. 2008..Therefore, direct projections can be identified from tonotopically organized auditory cortex to the earliest stages of visual cortical processing... 
Learning to see the trees before the forest: reversible deactivation of the superior colliculus during learning of local and global visual featuresStephen G Lomber
Cerebral Systems Laboratory, School of Human Development, University of Texas at Dallas, Richardson, TX 75083 0688, USA
Proc Natl Acad Sci U S A 99:4049-54. 2002..Therefore, deactivation of the superficial layers of the SC during pattern discrimination learning reverses the precedence for global visual features that is typical of normal learning...- Areas of cat auditory cortex as defined by neurofilament proteins expressing SMI-32Jeffrey G Mellott
Centre for Brain and Mind, Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, The University of Western Ontario, Medical Sciences Building, Room 216, 1151 Richmond Street North, London, Ontario N6A 5C1, Canada
Hear Res 267:119-36. 2010..The ability to distinguish auditory areas with SMI-32 is valuable for the identification of auditory cerebral areas in electrophysiological, anatomical, and/or behavioral investigations... - Cancellation of visuoparietal lesion-induced spatial neglectBertram R Payne
Cerebral Dynamics, Department of Anatomy and Neurobiology, Boston University School of Medicine, 700 Albany Street, Boston, MA 02118, USA
Exp Brain Res 150:395-8. 2003.... - Cooling produces minimal neuropathology in neocortex and hippocampusXiao-feng Yang
Department of Neurology-Box 8111, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA
Neurobiol Dis 23:637-43. 2006..While there may be biochemical and functional alterations in brain cooled as low as 5 degrees C, the neuropathological consequences of brain cooling appear to be insignificant... - Impact of repetitive transcranial magnetic stimulation of the parietal cortex on metabolic brain activity: a 14C-2DG tracing study in the catAntoni Valero-Cabre
Cerebral Dynamics, Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA
Exp Brain Res 163:1-12. 2005..Thus, in the anesthetized animal, the impact of rTMS is upon a distributed network of structures connected to the primary site of application... - Integrating motion and depth via parallel pathwaysCarlos R Ponce
Harvard MIT Division of Health Sciences and Technology, Harvard Medical School, 260 Longwood Avenue, Boston, Massachusetts 02115, USA
Nat Neurosci 11:216-23. 2008.... - Functional impact of primary visual cortex deactivation on subcortical target structures in the thalamus and midbrainR Jarrett Rushmore
Cerebral Dynamics and Neural Plasticity, Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
J Comp Neurol 488:414-26. 2005..We discuss these findings in terms of neural circuits and in terms of drivers and modulators... - Functional circuitry underlying visual neglectR Jarrett Rushmore
Laboratory of Cerebral Dynamics, Plasticity and Rehabilitation Department of Anatomy and Neurobiology, Boston University School of Medicine Boston, MA 02118, USA
Brain 129:1803-21. 2006..These results suggest that the most effective therapies for visual neglect will be those that act to decrease neural activity in the intermediate layers of the SC contralateral to the brain damage... - Pattern motion selectivity in population responses of area 18Kerstin E Schmidt
Max Planck Institute for Brain Research, Deutschordenstrasse 46, 60528 Frankfurt, Germany
Eur J Neurosci 24:2363-74. 2006.... - Restoration of visual orienting into a cortically blind hemifield by reversible deactivation of posterior parietal cortex or the superior colliculusStephen G Lomber
Laboratory for Visual Perception and Cognition, Department of Anatomy and Neurobiology, Boston University School of Medicine, 700 Albany Street, Boston, MA 02118, USA
Exp Brain Res 142:463-74. 2002..The results are discussed in terms of excitation and disinhibition of visual circuits... - Quantitative analyses of principal and secondary compound parieto-occipital feedback pathways in catBertram R Payne
Cerebral Dynamics, Center for Advanced Biomedical Research, Boston University School of Medicine, 700 Albany Street, Boston, MA 02118, USA
Exp Brain Res 152:420-33. 2003..MS cortex in the contralateral hemisphere also innervates area 18 directly. These data are important for interpreting the impact of deactivating feedback projections from visuoparietal cortex on occipital cortex... - The role of feedback in shaping neural representations in cat visual cortexRalf A W Galuske
Department of Neurophysiology, Max Planck Institute for Brain Research, 60528 Frankfurt am Main, Germany Europe
Proc Natl Acad Sci U S A 99:17083-8. 2002..Thus we propose that higher cortical areas have significant influence over fundamental neuronal properties as they emerge in lower areas...
Research Grants
- DEVELOPMENT OF fMRI COMPATIBLE REVERSIBLE DEACTIVATIONSTEPHEN LOMBER; Fiscal Year: 2005..Such a development should have wide appeal and will greatly advance our ability to dissect functional circuits with fMRI. ..
- CEREBRAL ORGANIZATION FOLLOWING COCHLEAR IMPLANTSTEPHEN LOMBER; Fiscal Year: 2005..The results from these studies will be directly applicable to clinical situations concerning the functional outcomes of cochlear implants in young children. ..