Lisa M Lix

Summary

Affiliation: University of Manitoba
Country: Canada

Publications

  1. ncbi request reprint Validity of the RAI-MDS for ascertaining diabetes and comorbid conditions in long-term care facility residents
    Lisa M Lix
    University of Manitoba, Winnipeg, MB, Canada
    BMC Health Serv Res 14:17. 2014
  2. pmc Predictive performance of comorbidity measures in administrative databases for diabetes cohorts
    Lisa M Lix
    Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada
    BMC Health Serv Res 13:340. 2013
  3. pmc The effects of a long-term care walking program on balance, falls and well-being
    Vanina P M Dal Bello-Haas
    School of Rehabilitation Sciences, McMaster University, Hamilton, Ontario, Canada
    BMC Geriatr 12:76. 2012
  4. doi request reprint Longitudinal study of quality of life and psychological functioning for active, fluctuating, and inactive disease patterns in inflammatory bowel disease
    Lisa M Lix
    Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada
    Inflamm Bowel Dis 14:1575-84. 2008
  5. doi request reprint Selection of women aged 50-64 yr for bone density measurement
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, MB, Canada Electronic address
    J Clin Densitom 16:570-8. 2013
  6. doi request reprint Does osteoporosis therapy invalidate FRAX for fracture prediction?
    William D Leslie
    Department of Medicine C5121, University of Manitoba, 409 Tache Avenue, Winnipeg, Manitoba, Canada
    J Bone Miner Res 27:1243-51. 2012
  7. doi request reprint Proton-pump inhibitor use is not associated with osteoporosis or accelerated bone mineral density loss
    Laura E Targownik
    Section of Gastroenterology, Division of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Gastroenterology 138:896-904. 2010
  8. doi request reprint Absolute fracture risk assessment using lumbar spine and femoral neck bone density measurements: derivation and validation of a hybrid system
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    J Bone Miner Res 26:460-7. 2011
  9. doi request reprint Validation of ten-year fracture risk prediction: a clinical cohort study from the Manitoba Bone Density Program
    William D Leslie
    Department of Medicine C5121, 409 Tache Avenue, Winnipeg, Manitoba, Canada
    Bone 43:667-71. 2008
  10. doi request reprint Effects of FRAX(®) model calibration on intervention rates: a simulation study
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    J Clin Densitom 14:272-8. 2011

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Validity of the RAI-MDS for ascertaining diabetes and comorbid conditions in long-term care facility residents
    Lisa M Lix
    University of Manitoba, Winnipeg, MB, Canada
    BMC Health Serv Res 14:17. 2014
    ..This study assessed the validity of the Resident Assessment Instrument Minimum Data Set (RAI-MDS) Version 2.0 for diagnoses of diabetes and comorbid conditions in residents of long-term care facilities (LTCFs)...
  2. pmc Predictive performance of comorbidity measures in administrative databases for diabetes cohorts
    Lisa M Lix
    Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada
    BMC Health Serv Res 13:340. 2013
    ..The objectives were to evaluate performance for: (a) disease-specific and general health outcomes, (b) data based on the ICD-9 and ICD-10 diagnoses, and (c) different age groups...
  3. pmc The effects of a long-term care walking program on balance, falls and well-being
    Vanina P M Dal Bello-Haas
    School of Rehabilitation Sciences, McMaster University, Hamilton, Ontario, Canada
    BMC Geriatr 12:76. 2012
    ....
  4. doi request reprint Longitudinal study of quality of life and psychological functioning for active, fluctuating, and inactive disease patterns in inflammatory bowel disease
    Lisa M Lix
    Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada
    Inflamm Bowel Dis 14:1575-84. 2008
    ..The aim was to assess quality of life (QOL) and psychological functioning in inflammatory bowel disease (IBD) as related to patterns of disease activity over time...
  5. doi request reprint Selection of women aged 50-64 yr for bone density measurement
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, MB, Canada Electronic address
    J Clin Densitom 16:570-8. 2013
    ..These data may help to inform an evidence-based approach for targeting BMD testing in postmenopausal women younger than 65yr under the NOF treatment guidelines...
  6. doi request reprint Does osteoporosis therapy invalidate FRAX for fracture prediction?
    William D Leslie
    Department of Medicine C5121, University of Manitoba, 409 Tache Avenue, Winnipeg, Manitoba, Canada
    J Bone Miner Res 27:1243-51. 2012
    ..Although FRAX should not be used to assess the reduction in fracture risk in individuals on treatment, it may still have value for guiding the need for continued treatment or treatment withdrawal..
  7. doi request reprint Proton-pump inhibitor use is not associated with osteoporosis or accelerated bone mineral density loss
    Laura E Targownik
    Section of Gastroenterology, Division of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Gastroenterology 138:896-904. 2010
    ..The mechanism by which PPI use promotes the development of hip fracture is uncharacterized. Therefore, we sought to determine whether PPI use is associated with osteoporosis or accelerated bone mineral density (BMD) loss...
  8. doi request reprint Absolute fracture risk assessment using lumbar spine and femoral neck bone density measurements: derivation and validation of a hybrid system
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    J Bone Miner Res 26:460-7. 2011
    ..The improvement in fracture risk prediction is small but supports clinical interest in a system that integrates LS in fracture risk assessment...
  9. doi request reprint Validation of ten-year fracture risk prediction: a clinical cohort study from the Manitoba Bone Density Program
    William D Leslie
    Department of Medicine C5121, 409 Tache Avenue, Winnipeg, Manitoba, Canada
    Bone 43:667-71. 2008
    ..Absolute 10-year fracture risk is the preferred method for fracture risk assessment. The validity of applying published fracture rates from one population to another population is uncertain...
  10. doi request reprint Effects of FRAX(®) model calibration on intervention rates: a simulation study
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    J Clin Densitom 14:272-8. 2011
    ..These results highlight the importance of FRAX(®) model calibration, and speak to the importance of using high-quality fracture epidemiology in constructing FRAX(®) tools...
  11. doi request reprint Simplified 10-year absolute fracture risk assessment: a comparison of men and women
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    J Clin Densitom 13:141-6. 2010
    ..Despite evidence of greater referral bias in men resulting in a higher rate of clinical risk factors, the performance of the prediction algorithm was not affected...
  12. ncbi request reprint Fracture risk in androgen deprivation therapy: a Canadian population based analysis
    Yiu Keung Lau
    Department of Medical Oncology and Hematology, CancerCare Manitoba, Winnipeg, Manitoba, Canada
    Can J Urol 16:4908-14. 2009
    ..We sought to confirm the higher fracture risk of men with prostate cancer on ADT in the Canadian population...
  13. doi request reprint Imputation of 10-year osteoporotic fracture rates from hip fractures: a clinical validation study
    William D Leslie
    Faculty of Medicine, University of Manitoba, Winnipeg, Canada
    J Bone Miner Res 25:388-92. 2010
    ..Since collection of population-based hip fracture data is considerably easier than collection of non-hip fracture data, this study supports the current emphasis on using hip fractures as the preferred site for FRAX model calibration...
  14. doi request reprint Health-related quality of life after stroke: does response shift occur in self-perceived physical function?
    Ruth Barclay-Goddard
    Department of Physical Therapy, School of Medical Rehabilitation, University of Manitoba, Winnipeg, Canada
    Arch Phys Med Rehabil 92:1762-9. 2011
    ..To determine whether response shift (a change in the self-perceived meaning of health-related quality of life [HRQL]) was present in a model of physical function over time poststroke...
  15. doi request reprint A before-and-after study of fracture risk reporting and osteoporosis treatment initiation
    William D Leslie
    University of Manitoba, Winnipeg, Canada
    Ann Intern Med 153:580-6. 2010
    ..Several national organizations recommend that fracture risk assessment and osteoporotic treatment be based on estimated absolute 10-year fracture risk rather than bone mineral density (BMD) alone...
  16. pmc Use of proton pump inhibitors and risk of osteoporosis-related fractures
    Laura E Targownik
    Department of Gastroenterology, Division of Internal Medicine, University of Manitoba, Winnipeg, Man
    CMAJ 179:319-26. 2008
    ..The use of proton pump inhibitors has been associated with an increased risk of hip fracture. We sought to further explore the relation between duration of exposure to proton pump inhibitors and osteoporosis-related fractures...
  17. doi request reprint Temporal trends in obesity, osteoporosis treatment, bone mineral density, and fracture rates: a population-based historical cohort study
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    J Bone Miner Res 29:952-9. 2014
    ..5%; 95% CI, -1.8 to +1.0). In summary, major osteoporotic fracture rates declined substantially and linearly from 1996 to 2006, and this was explained by improvements in BMD rather than greater rates of obesity or osteoporosis treatment...
  18. ncbi request reprint The disconnect between better quality of glucocorticoid-induced osteoporosis preventive care and better outcomes: a population-based cohort study
    Sumit R Majumdar
    From the Department of Medicine, University of Alberta, Edmonton, Alberta the Departments of Community Health Sciences and Medicine and Radiology, University of Manitoba, Winnipeg, Manitoba and the Department of Medicine, McGill University, Montreal, Quebec, Canada
    J Rheumatol 40:1736-41. 2013
    ..The assumption that improvements in GIOP preventive care will lead to better outcomes has not been tested...
  19. doi request reprint Independent clinical validation of a Canadian FRAX tool: fracture prediction and model calibration
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    J Bone Miner Res 25:2350-8. 2010
    ..In conclusion, a Canadian FRAX tool calibrated on national hip fracture data generates fracture risk predictions that generally are consistent with observed fracture rates across a wide range of risk categories...
  20. doi request reprint Simplified system for absolute fracture risk assessment: clinical validation in Canadian women
    William D Leslie
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    J Bone Miner Res 24:353-60. 2009
    ..3-16.4] per 1000 person-years) or major CS use (11.2 [95% CI, 4.1-18.2] per 1000 person-years). This simplified fracture risk assessment system provides an assessment of fracture risk that is consistent with observed fracture rates...
  21. doi request reprint Effect of total hip bone area on osteoporosis diagnosis and fractures
    William D Leslie
    Faculty of Medicine, University of Manitoba, Winnipeg, Canada
    J Bone Miner Res 23:1468-76. 2008
    ..Incident fracture rates correlate equally well with BMD across all bone area quartiles when adjusted for age...
  22. ncbi request reprint Major osteoporotic to hip fracture ratios in canadian men and women with Swedish comparisons: a population-based analysis
    Anna Lam
    University of Manitoba, Winnipeg, Canada
    J Bone Miner Res 29:1067-73. 2014
    ..These differences have implications for updating and calibrating FRAX tools, fracture risk estimation, and intervention rates. Moreover, wherever possible, it is important that countries try to collect accurate non-hip fracture data...
  23. doi request reprint The Manitoba IBD Index: evidence for a new and simple indicator of IBD activity
    Ian Clara
    University of Manitoba Inflammatory Bowel Disease Clinical and Research Centre, Winnipeg, Manitoba, Canada
    Am J Gastroenterol 104:1754-63. 2009
    ....
  24. ncbi request reprint Healthcare utilization in patients with Parkinson's disease: a population-based analysis
    Douglas E Hobson
    Movement Disorder Clinic, 200 Woodlawn Street, Winnipeg, Manitoba, Canada
    Parkinsonism Relat Disord 18:930-5. 2012
    ..To investigate factors associated with healthcare utilization and prescription drug use for Parkinson's disease (PD) patients and matched controls...
  25. doi request reprint Using multiple data features improved the validity of osteoporosis case ascertainment from administrative databases
    Lisa M Lix
    Manitoba Centre for Health Policy, University of Manitoba, Canada
    J Clin Epidemiol 61:1250-60. 2008
    ..The aim was to construct and validate algorithms for osteoporosis case ascertainment from administrative databases and to estimate the population prevalence of osteoporosis for these algorithms...
  26. doi request reprint Response shift was identified over multiple occasions with a structural equation modeling framework
    Ruth Barclay-Goddard
    Department of Physical Therapy, School of Medical Rehabilitation, University of Manitoba, R106 771 McDermot Avenue, Winnipeg, Manitoba, Canada
    J Clin Epidemiol 62:1181-8. 2009
    ..To develop and apply a framework that uses structural equation modeling to identify response shift (RS) in data with more than two time points...
  27. doi request reprint Body composition and bone density in Canadian White and Aboriginal women: the First Nations Bone Health Study
    William D Leslie
    University of Manitoba, Department of Medicine, Canada
    Bone 42:990-5. 2008
    ....
  28. ncbi request reprint Single-site vs multisite bone density measurement for fracture prediction
    William D Leslie
    Faculty of Medicine, University of Manitoba, Winnipeg, MB R2H 2A6, Canada
    Arch Intern Med 167:1641-7. 2007
    ..Bone density measurement with dual-energy x-ray absorptiometry is widely used for fracture risk assessment. Discordance between measurement sites is common, but it is unclear how this affects fracture prediction...
  29. doi request reprint Outcomes among 3.5 million newly diagnosed hypertensive Canadians
    Hude Quan
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Can J Cardiol 29:592-7. 2013
    ..This population-based study assessed rates of all-cause mortality, myocardial infarction, heart failure, and stroke for up to 12 years of follow-up in 3.5 million Canadian adults newly diagnosed with hypertension...
  30. doi request reprint Direct costs of fractures in Canada and trends 1996-2006: a population-based cost-of-illness analysis
    William D Leslie
    Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    J Bone Miner Res 26:2419-29. 2011
    ..We found that there are large incremental health care costs associated with incident fractures in Canada. Identifying COI from HCR use offers a cost baseline for measuring the effects of evidence-based guidelines implementation...
  31. pmc Ethnic and regional differences in prevalence and correlates of chronic diseases and risk factors in northern Canada
    Joykrishna Sarkar
    University of Manitoba, Winnipeg, Canada
    Prev Chronic Dis 7:A13. 2010
    ..We investigated ethnic and geographic variations in major chronic diseases and risk factors in northern Canada, an area that is undergoing rapid changes in its social, cultural, and physical environments...
  32. ncbi request reprint Biphasic fracture risk in diabetes: a population-based study
    William D Leslie
    Department of Medicine C5121, University of Manitoba, 409 Tache Avenue, Winnipeg, Manitoba, Canada R2H 2A6
    Bone 40:1595-601. 2007
    ..It is hypothesized that the opposing effects of overweight/obesity and diabetes-related complications contribute to the observed biphasic fracture risk, though causality cannot be proven from this observational study...
  33. ncbi request reprint Residential mobility of individuals with diagnosed schizophrenia: a comparison of single and multiple movers
    Lisa M Lix
    Dept of Community Health Sciences, Manitoba Centre for Health Policy, University of Manitoba, 408 727 McDermot Avenue, Winnipeg, MB, R3E 3P5, Canada
    Soc Psychiatry Psychiatr Epidemiol 42:221-8. 2007
    ..Little research has been undertaken to describe differences between single (i.e., infrequent) and multiple (i.e., frequent) movers with schizophrenia, and the association between frequency of mobility and health and health service use...