Nir Lipsman

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi Informed consent for clinical trials of deep brain stimulation in psychiatric disease: challenges and implications for trial design
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, ON, Canada
    J Med Ethics 38:107-11. 2012
  2. pmc Intracranial Applications of Magnetic Resonance-guided Focused Ultrasound
    Nir Lipsman
    Division of Neurosurgery, University Health Network, University of Toronto, 399 Bathurst Street, 4W 431, Toronoto, M5T 2S8, Canada
    Neurotherapeutics 11:593-605. 2014
  3. ncbi A psychiatric primer for the functional neurosurgeon
    N Lipsman
    University of Toronto, Toronto, Canada
    J Neurosurg Sci 56:209-20. 2012
  4. ncbi Criteria for the ethical conduct of psychiatric neurosurgery clinical trials
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Canada
    Neurosurg Focus 29:E9. 2010
  5. doi Neurosurgical treatment of bipolar depression: defining treatment resistance and identifying surgical targets
    Nir Lipsman
    Division of Neurosurgery, University Health Network Department of Psychiatry, University of Toronto, University Health Network, 399 Bathurst Street, Toronto, Ontario, Canada
    Bipolar Disord 12:691-701. 2010
  6. doi The contemporary practice of psychiatric surgery: results from a global survey of functional neurosurgeons
    Daniel Mendelsohn
    Division of Neurosurgery, Vancouver General Hospital, University of British Columbia, Vancouver, B C, Canada
    Stereotact Funct Neurosurg 91:306-13. 2013
  7. ncbi Neurosurgical treatment of anorexia nervosa: review of the literature from leucotomy to deep brain stimulation
    Nir Lipsman
    Division of Neurosurgery, University Health Network, University of Toronto, Toronto, ON, Canada
    Eur Eat Disord Rev 21:428-35. 2013
  8. doi Measuring impact in stereotactic and functional neurosurgery: an analysis of the top 100 most highly cited works and the citation classics in the field
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ont, Canada
    Stereotact Funct Neurosurg 90:201-9. 2012
  9. doi Neurosurgeons' perspectives on psychosurgery and neuroenhancement: a qualitative study at one center
    Daniel Mendelsohn
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Ontario, Canada
    J Neurosurg 113:1212-8. 2010
  10. doi The contemporary practice of psychiatric surgery: results from a survey of North American functional neurosurgeons
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ont, Canada
    Stereotact Funct Neurosurg 89:103-10. 2011

Collaborators

Detail Information

Publications27

  1. ncbi Informed consent for clinical trials of deep brain stimulation in psychiatric disease: challenges and implications for trial design
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, ON, Canada
    J Med Ethics 38:107-11. 2012
    ..Recommendations are also made for an ethical approach to clinical trial consent acquisition in this unique patient population...
  2. pmc Intracranial Applications of Magnetic Resonance-guided Focused Ultrasound
    Nir Lipsman
    Division of Neurosurgery, University Health Network, University of Toronto, 399 Bathurst Street, 4W 431, Toronoto, M5T 2S8, Canada
    Neurotherapeutics 11:593-605. 2014
    ..We review the principles of MRgFUS and its use for brain-based disorders, and outline future directions for this promising technology. ..
  3. ncbi A psychiatric primer for the functional neurosurgeon
    N Lipsman
    University of Toronto, Toronto, Canada
    J Neurosurg Sci 56:209-20. 2012
    ....
  4. ncbi Criteria for the ethical conduct of psychiatric neurosurgery clinical trials
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Canada
    Neurosurg Focus 29:E9. 2010
    ..Ethical criteria, such as the ones proposed here, need to be established now and applied in earnest if the field is to move forward and if patients with no other therapeutic options are to receive much-needed treatment...
  5. doi Neurosurgical treatment of bipolar depression: defining treatment resistance and identifying surgical targets
    Nir Lipsman
    Division of Neurosurgery, University Health Network Department of Psychiatry, University of Toronto, University Health Network, 399 Bathurst Street, Toronto, Ontario, Canada
    Bipolar Disord 12:691-701. 2010
    ..Herein, we provide the rationale for employing DBS as an alternative treatment avenue in individuals with bipolar depression...
  6. doi The contemporary practice of psychiatric surgery: results from a global survey of functional neurosurgeons
    Daniel Mendelsohn
    Division of Neurosurgery, Vancouver General Hospital, University of British Columbia, Vancouver, B C, Canada
    Stereotact Funct Neurosurg 91:306-13. 2013
    ..We previously reported the results of a survey of North American functional neurosurgeons that evaluated general attitudes towards NPD and the future directions of the field...
  7. ncbi Neurosurgical treatment of anorexia nervosa: review of the literature from leucotomy to deep brain stimulation
    Nir Lipsman
    Division of Neurosurgery, University Health Network, University of Toronto, Toronto, ON, Canada
    Eur Eat Disord Rev 21:428-35. 2013
    ..This has translated into the development of novel, focused therapeutic options for patients with treatment-refractory AN...
  8. doi Measuring impact in stereotactic and functional neurosurgery: an analysis of the top 100 most highly cited works and the citation classics in the field
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ont, Canada
    Stereotact Funct Neurosurg 90:201-9. 2012
    ..For example, papers that have been cited at least 400 times are designated 'citation classics' or works that, by virtue of very high citations, have been deemed of particular importance by researchers working in related disciplines...
  9. doi Neurosurgeons' perspectives on psychosurgery and neuroenhancement: a qualitative study at one center
    Daniel Mendelsohn
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Ontario, Canada
    J Neurosurg 113:1212-8. 2010
    ..The authors sought to gauge the opinions of neurosurgical staff and trainees toward various uses of neuromodulation technology including psychosurgery and neuroenhancement...
  10. doi The contemporary practice of psychiatric surgery: results from a survey of North American functional neurosurgeons
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ont, Canada
    Stereotact Funct Neurosurg 89:103-10. 2011
    ..Given the troubled history of the field and its current renaissance, it is important to evaluate current practices, to serve as a baseline for future comparison, and to gauge changing cultural attitudes towards invasive neuromodulation...
  11. ncbi MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study
    Nir Lipsman
    Division of Neurosurgery, Department of Surgery, Krembil Neuroscience Centre, Toronto Western Hospital, University of Toronto, Toronto, ON M5T 2S8, Canada
    Lancet Neurol 12:462-8. 2013
    ..MR-guided focused ultrasound has been developed as a non-invasive means of generating precisely placed focal lesions. We examined its application to the management of essential tremor...
  12. doi A narrative history of the International Society for Psychiatric Surgery: 1970-1983
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ont, Canada nir lipsman utoronto ca
    Stereotact Funct Neurosurg 90:347-55. 2012
    ....
  13. ncbi Trends in anorexia nervosa research: an analysis of the top 100 most cited works
    Nir Lipsman
    Division of Neurosurgery, Department of Surgery, University Health Network, University of Toronto, Toronto, Canada
    Eur Eat Disord Rev 22:9-14. 2014
    ..Although reasonably diverse, the top 100 papers highlight areas still lagging behind, including the neuroscience of AN as well as research into novel treatment strategies...
  14. doi Probing and regulating dysfunctional circuits using deep brain stimulation
    Andres M Lozano
    Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, Krembil Neuroscience Center, University of Toronto, Toronto, ON M5T 2S8, Canada
    Neuron 77:406-24. 2013
    ..Here we review recent advances in the DBS field and discuss potential future directions in targeted intracranial neuromodulation...
  15. ncbi Beta coherence within human ventromedial prefrontal cortex precedes affective value choices
    Nir Lipsman
    Division of Neurosurgery, Krembil Neuroscience Centre and Toronto Western Research Institute, University Health Network, Department of Surgery, University of Toronto, 399 Bathurst, Toronto, Ontario M5T 2S8, Canada
    Neuroimage 85:769-78. 2014
    ....
  16. doi Deep brain stimulation in obsessive-compulsive disorder: neurocircuitry and clinical experience
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Canada
    Handb Clin Neurol 116:245-50. 2013
    ..These results imply that a common underlying circuit is being modulated, and moreover that there is room for improvement, and debate, in the development of an evidence-driven DBS treatment for this chronic, debilitating illness. ..
  17. doi Evaluating the potential of deep brain stimulation for treatment-resistant anorexia nervosa
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Canada
    Handb Clin Neurol 116:271-6. 2013
    ..As a result, the use of DBS in treatment-resistant anorexia nervosa should be evaluated in carefully designed, early-phase feasibility trials. ..
  18. ncbi Regional anatomy of the pedunculopontine nucleus: relevance for deep brain stimulation
    Marie Pierre Fournier-Gosselin
    Division of Neurosurgery, Hopital Notre Dame, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Mov Disord 28:1330-6. 2013
    ..By providing a functional map and representative schematics of the PPN region, we hope to optimize the placement of deep brain stimulation electrodes, thereby maximizing safety and clinical efficacy...
  19. pmc Patients' perception of the informed consent process for neurooncology clinical trials
    Eva Knifed
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada
    Neuro Oncol 10:348-54. 2008
    ....
  20. ncbi Current and future indications for deep brain stimulation in pediatric populations
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Ontario, Canada
    Neurosurg Focus 29:E2. 2010
    ..The authors conclude that DBS in children can and should be considered a valid and effective treatment option, albeit in highly specific and carefully selected cases...
  21. pmc Deep brain stimulation for disorders of memory and cognition
    Tejas Sankar
    Division of Neurosurgery, Walter C Mackenzie Health Sciences Centre, University of Alberta, 8440 112 Street, Edmonton, Alberta, T6G 2B7, Canada
    Neurotherapeutics 11:527-34. 2014
    ..Such work holds promise as a novel therapeutic approach for one of medicine's most urgent priorities. ..
  22. doi Subcallosal cingulate deep brain stimulation for treatment-refractory anorexia nervosa: a phase 1 pilot trial
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
    Lancet 381:1361-70. 2013
    ..We aimed to assess the safety of DBS to modulate the activity of limbic circuits and to examine how this might affect the clinical features of anorexia nervosa...
  23. doi Personal identity, enhancement and neurosurgery: a qualitative study in applied neuroethics
    Nir Lipsman
    University of Toronto, Toronto, Ontario, Canada
    Bioethics 23:375-83. 2009
    ..The results provide insight into how patients approach their identity prior to potentially identity-altering procedures and what future ethical challenges lay ahead for clinicians and researchers in the field of neurotherapeutics...
  24. doi The most cited works in major depression: the 'Citation classics'
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Canada
    J Affect Disord 134:39-44. 2011
    ..We were interested in identifying such papers in the field of Major Depression...
  25. doi Brain stimulation methods to treat tobacco addiction
    Victoria C Wing
    Biobehavioural Addictions and Concurrent Disorders Research Laboratory, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Brain Stimul 6:221-30. 2013
    ..Brain stimulation methods are gaining increasing interest as possible addiction therapeutics...
  26. ncbi Brain-machine interfaces for motor control: a guide for neuroscience clinicians
    Allan Martin
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, M5T 2S8, Canada
    Can J Neurol Sci 39:11-22. 2012
    ..Ultimately, we hope to help neuroscience clinicians understand and participate in this burgeoning field...
  27. ncbi Deep brain stimulation for treatment-refractory obsessive-compulsive disorder: the search for a valid target
    Nir Lipsman
    Division of Neurosurgery, Toronto Western Hospital, University Health Network and University of Toronto, Toronto, Canada
    Neurosurgery 61:1-11; discussion 11-3. 2007
    ..We hope that a research-driven approach, premised on converging evidence and previous experience, will lead to a safe and effective DBS procedure that will benefit patients who remain disabled despite presently available therapies...