- Activity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cellsJohn P Wiebe
Hormonal Regulatory Mechanisms Laboratory, Department of Biology, University of Western Ontario, London, Ontario, Canada N6A 5B7
BMC Cancer 3:9. 2003....
- Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinomaMichael J Lewis
Department of Biology University of Western Ontario, London, Canada
BMC Cancer 4:27. 2004..The aim of this study was to determine if the differences in enzyme activities between tumorous and nontumorous breast tissues are associated with differences in progesterone metabolizing enzyme gene expression...