A R Levy

..The question of how to implement the recommendations remains to be elucidated, as does an evaluation of the trade-offs between costs and benefits of obtaining better information on cost-effectiveness...

..The objective of this analysis was to compare survival after the treatment decision between patients who underwent CABG and those who remained untreated...

..Our objective was to compare the cumulative incidence for death on the wait list according to the length of wait lists at the time of registration for the operation...

..We sought to determine what proportion of patients have had late coronary bypass surgery after registration on wait lists of different size in a network of hospitals with uniform standards for timing of surgery...

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..Therefore, we sought to improve the estimates of the risk of death associated with delayed surgical treatment of coronary artery disease...

..The objective of the paper is to illustrate how to construct and interpret a CEAC...

..The purpose of this study was to estimate the cost-effectiveness of beta-blocker therapy with either metoprolol or carvedilol in addition to conventional therapy for patients with heart failure (HF) in Canada...

..To estimate the reduction in all-cause mortality conferred by beta-blockers in a population-based cohort of elderly survivors of myocardial infarction during the year following hospital discharge...

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..There is scant population-based information on the age and sex distributions of patients receiving these medications...

..It is therefore difficult to ascertain whether higher operative mortality among women is due to biological differences or to delayed access to elective CABG...

..We sought to determine whether the period of registration on wait lists had an effect on time to isolated CABG and whether the period effect was similar across priority groups...

..To describe patterns of healthcare resource utilisation and associated costs for patients with advanced melanoma in the United Kingdom (UK), Italy, and France...

..We evaluated whether longer delays contribute to the probability of death before surgery among patients prioritized into the less urgent category...

..Prospective cohort study of patients registered for elective surgical lumbar discectomy (ESLD) between November 1999 and December 2003 at a major tertiary care center in Vancouver...

..4%, dementia with Lewy bodies 2.5%, and unclassifiable 1.8%. The ACCORD cohort will allow a detailed study of the longitudinal course of CIND, and the longer-term outcomes of both treated and untreated dementia subjects...

..If the impact on survival seen in these trials compares to that seen in observational studies, LABA and the combination treatment are likely to be cost-effective in the United States...

..However, prescribing differed by training characteristics such as medical specialty and year and medical school of graduation...

..We estimate the effects of beta-blocker therapy on one-year all-cause mortality after an incident hospitalization for heart failure, in the absence of data describing disease severity, which is believed to be a confounder...

..The administration of proton pump inhibitors intravenously after endoscopic treatment of peptic ulcers significantly reduces the recurrence of bleeding...

..Moreover, a particular computational approach for posterior inference is developed, because application of MCMC in a standard manner is seen to be ineffective in this problem...

..The objective here was to compare the direct medical costs of kidney, liver, heart, and lung transplantations in British Columbia (BC), Canada...

..The Morisky medication adherence scale is a commonly used adherence screening tool. It is composed of 4 yes/no questions about past medication use patterns and is thus quick and simple to use during drug history interviews...

..These results provide powerful additional motivation to accelerate the roll out of HAART programs aggressively targeting those in medical need, both for their own benefit and as a means of decreasing new HIV infections...

..This study determined the relationship between the number of medications dispensed and adherence with chronic cardiovascular regimens...

..Methods: Analysis was based on a cohort of individuals initiating HAART between 1996 and 2001. The primary outcome was hospitalization for one or more days. Survival methods were used to assess the impact of adherence on hospitalization...

..CONCLUSIONS: The rate of ICP among HIV-positive individuals on ART appears to be increasing; in addition, the duration of time on ART is independently associated with ICP after adjustment for patient demographic characteristics...

..These findings highlight the importance of closely monitoring patients starting therapy with low CD4 cell counts in order to mediate or prevent outcomes requiring hospitalization...

..Our objective is to investigate the performance of the method compared to sensitivity analysis, which assumes that there is no relationship between measured and unmeasured confounders...

..We describe type, frequency, severity, seriousness, and onset time of adverse drug events and test the hypothesis that fomepizole results in fewer adverse drug events than ethanol...

..The purpose was to estimate preference weights from the general population in four developed countries for standardized health states experienced by persons with CML...

..Using 2 Canadian population surveys, the purpose of this study was to identify changes in health-related quality of life in individuals with stroke from 1996 to 2005...

..We estimated the incremental cost-effectiveness of 10 strategies for colorectal cancer screening, as well as no screening, incorporating quality of life, noncompliance and data on the costs and benefits of chemotherapy...

..While the basic method applies to piecewise-constant hazards and covariate effects, it is easy to apply importance sampling to consider smoother functions...

..The aim of the study was to determine whether the use of specialist transport personnel improves patient outcome at the receiving hospital for critically ill patients transferred to higher centers...

..Pneumonia is a common reason for hospital admission, and the cost of treatment is primarily determined by length of stay (LOS)...

..001). CONCLUSION: Only a relatively low prevalence of multidrug resistance was observed in this cohort, indicating that the exhaustion of treatment options because of drug resistance was not a significant contributor to mortality...

..The primary objective of this study therefore, was to examine the relationship of SES to LOS and early re-admission among adult patients hospitalized with community-acquired pneumonia in a setting with universal health insurance...

..We evaluated the effect of reference-based pricing for H2RAs and special authority for PPIs on dispensing and reimbursement for senior citizen beneficiaries of BC Pharmacare...

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..CONCLUSIONS: Type 2 RP of NSAIDs achieved its goal of reducing drug expenditures and was more effective than Type 1 RP. The effects of RP on patient health and associated health care costs remain to be investigated...

..This study tested the predictive role of psychological distress in cancer survival, while attempting to overcome several important methodological and statistical limitations that have clouded the issue...

..Consequently, economic factors often play a role in guiding treatment selection...