Richard S T Leung

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. doi request reprint Mechanisms of sleep-disordered breathing: causes and consequences
    Richard S T Leung
    St Michael s Hospital Sleep Laboratory, 6 045 Bond Wing, 30 Bond Street, Toronto, ON, Canada
    Pflugers Arch 463:213-30. 2012
  2. doi request reprint Sleep-disordered breathing: autonomic mechanisms and arrhythmias
    Richard S T Leung
    St Michael s Hospital Sleep Laboratory and the University of Toronto, 30 Bond Street, Toronto, Ontario, Canada
    Prog Cardiovasc Dis 51:324-38. 2009
  3. ncbi request reprint Respiratory modulation of heart rate and blood pressure during Cheyne-Stokes respiration
    Richard S T Leung
    Toronto General Hospital University Health Network, Centre for Sleep Medicine and Circadian Biology, University of Toronto, Ontario, Canada
    J Electrocardiol 36:213-7. 2003
  4. ncbi request reprint Influence of Cheyne-Stokes respiration on ventricular response to atrial fibrillation in heart failure
    Richard S T Leung
    Toronto Rehabilitation Institute Sleep Research Laboratory, Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
    J Appl Physiol 99:1689-96. 2005
  5. ncbi request reprint Respiratory modulation of the autonomic nervous system during Cheyne-Stokes respiration
    Richard S T Leung
    University of Toronto Centre for Sleep and Chronobiology, ON, Canada
    Can J Physiol Pharmacol 84:61-6. 2006
  6. ncbi request reprint Provocation of ventricular ectopy by cheyne-stokes respiration in patients with heart failure
    Richard S T Leung
    University of Toronto Centre for Sleep Medicine and Circadian Biology, Ontario, Canada
    Sleep 27:1337-43. 2004
  7. ncbi request reprint Continuous positive airway pressure increases heart rate variability in heart failure patients with obstructive sleep apnoea
    Matthew P Gilman
    Sleep and Cardiovascular Physiology Research Laboratories, Mount Sinai Hospital, Toronto, ON, Canada
    Clin Sci (Lond) 114:243-9. 2008
  8. ncbi request reprint Association between atrial fibrillation and central sleep apnea
    Richard S T Leung
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Ontario, Canada
    Sleep 28:1543-6. 2005
  9. ncbi request reprint Avoidance of the left lateral decubitus position during sleep in patients with heart failure: relationship to cardiac size and function
    Richard S T Leung
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Ontario, Canada
    J Am Coll Cardiol 41:227-30. 2003
  10. ncbi request reprint Influence of Cheyne-Stokes respiration on cardiovascular oscillations in heart failure
    Richard S T Leung
    Toronto General Hospital UHN, NU 9 112, 200 Elizabeth Street, Toronto ON, M5G 2C4, Canada
    Am J Respir Crit Care Med 167:1534-9. 2003

Collaborators

Detail Information

Publications10

  1. doi request reprint Mechanisms of sleep-disordered breathing: causes and consequences
    Richard S T Leung
    St Michael s Hospital Sleep Laboratory, 6 045 Bond Wing, 30 Bond Street, Toronto, ON, Canada
    Pflugers Arch 463:213-30. 2012
    ..These underlying pathophysiological mechanisms provide a framework for understanding why OSA and CSA may predispose to cardiovascular diseases like ischemic heart disease and stroke...
  2. doi request reprint Sleep-disordered breathing: autonomic mechanisms and arrhythmias
    Richard S T Leung
    St Michael s Hospital Sleep Laboratory and the University of Toronto, 30 Bond Street, Toronto, Ontario, Canada
    Prog Cardiovasc Dis 51:324-38. 2009
    ..Therapy consists largely of treatment with continuous positive airway pressure, which has been shown to improve autonomic profile and reduce nocturnal arrhythmias...
  3. ncbi request reprint Respiratory modulation of heart rate and blood pressure during Cheyne-Stokes respiration
    Richard S T Leung
    Toronto General Hospital University Health Network, Centre for Sleep Medicine and Circadian Biology, University of Toronto, Ontario, Canada
    J Electrocardiol 36:213-7. 2003
    ..We conclude that ventilatory oscillations during Cheyne-Stokes respiration can modulate HR and BP independent of the effects of hypoxia and arousals from sleep...
  4. ncbi request reprint Influence of Cheyne-Stokes respiration on ventricular response to atrial fibrillation in heart failure
    Richard S T Leung
    Toronto Rehabilitation Institute Sleep Research Laboratory, Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
    J Appl Physiol 99:1689-96. 2005
    ....
  5. ncbi request reprint Respiratory modulation of the autonomic nervous system during Cheyne-Stokes respiration
    Richard S T Leung
    University of Toronto Centre for Sleep and Chronobiology, ON, Canada
    Can J Physiol Pharmacol 84:61-6. 2006
    ..It is speculated that the rhythmic oscillations in autonomic tone brought about by CSR may ultimately contribute to the sympatho-excitation and increased mortality long observed in patients with heart failure and CSR...
  6. ncbi request reprint Provocation of ventricular ectopy by cheyne-stokes respiration in patients with heart failure
    Richard S T Leung
    University of Toronto Centre for Sleep Medicine and Circadian Biology, Ontario, Canada
    Sleep 27:1337-43. 2004
    ..The objective of this study was to determine whether CSR-CSA directly provokes ventricular ectopy and, if so, whether it is associated with any particular phase of the CSR-CSA breathing cycle...
  7. ncbi request reprint Continuous positive airway pressure increases heart rate variability in heart failure patients with obstructive sleep apnoea
    Matthew P Gilman
    Sleep and Cardiovascular Physiology Research Laboratories, Mount Sinai Hospital, Toronto, ON, Canada
    Clin Sci (Lond) 114:243-9. 2008
    ..01). In conclusion, treatment of coexisting OSA by nocturnal CPAP in patients with heart failure increases HF-HRV during morning wakefulness, indicating improved vagal modulation of heart rate. This may contribute to improved prognosis...
  8. ncbi request reprint Association between atrial fibrillation and central sleep apnea
    Richard S T Leung
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Ontario, Canada
    Sleep 28:1543-6. 2005
    ..We hypothesized that the prevalence of atrial fibrillation might also be increased in patients with central sleep apnea in the absence of other cardiac disease...
  9. ncbi request reprint Avoidance of the left lateral decubitus position during sleep in patients with heart failure: relationship to cardiac size and function
    Richard S T Leung
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Ontario, Canada
    J Am Coll Cardiol 41:227-30. 2003
    ....
  10. ncbi request reprint Influence of Cheyne-Stokes respiration on cardiovascular oscillations in heart failure
    Richard S T Leung
    Toronto General Hospital UHN, NU 9 112, 200 Elizabeth Street, Toronto ON, M5G 2C4, Canada
    Am J Respir Crit Care Med 167:1534-9. 2003
    ..Cheyne-Stokes respiration is therefore one of the mechanisms that contributes to the very low-frequency oscillations in heart rate and blood pressure observed in patients with heart failure...