Kevin B Laupland

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. pmc Population-based laboratory surveillance for Giardia sp. and Cryptosporidium sp. infections in a large Canadian health region
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Infect Dis 5:72. 2005
  2. ncbi request reprint To close or not to close, that is one of the questions? Perceptions of Trauma Association of Canada surgical members on the management of the open abdomen
    Shahzeer Karmali
    Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 60:287-93. 2006
  3. pmc Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study
    Sean M Bagshaw
    Department of Critical Care Medicine, Calgary Health Region, University of Calgary, Calgary, Alberta, Canada
    Crit Care 9:R700-9. 2005
  4. ncbi request reprint Are occult pneumothoraces truly occult or simply missed?
    Chad G Ball
    Department of Surgery, Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 60:294-8 discussion 298-9. 2006
  5. pmc Prospective evaluation of hand-held focused abdominal sonography for trauma (FAST) in blunt abdominal trauma
    Andrew W Kirkpatrick
    Department of Critical Care Medicine, Foothills Medical Centre, Calgary, Alberta
    Can J Surg 48:453-60. 2005
  6. ncbi request reprint Incidence, risk factors, and outcomes for occult pneumothoraces in victims of major trauma
    Chad G Ball
    Department of Surgery, Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 59:917-24; discussion 924-5. 2005
  7. pmc Salmonella enterica bacteraemia: a multi-national population-based cohort study
    Kevin B Laupland
    Department of Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada
    BMC Infect Dis 10:95. 2010
  8. ncbi request reprint Investigation of sources of potential bias in laboratory surveillance for anti-microbial resistance
    Kevin B Laupland
    Department of Medicine, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    Clin Invest Med 30:E159-66. 2007
  9. ncbi request reprint One-year mortality of bloodstream infection-associated sepsis and septic shock among patients presenting to a regional critical care system
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, 3535 Research Road NW, Calgary, AB, T2L 2K8, Canada
    Intensive Care Med 31:213-9. 2005
  10. pmc Population-based laboratory surveillance for AmpC beta-lactamase-producing Escherichia coli, Calgary
    Johann D D Pitout
    University of Calgary, Calgary, Alberta, Canada
    Emerg Infect Dis 13:443-8. 2007

Detail Information

Publications86

  1. pmc Population-based laboratory surveillance for Giardia sp. and Cryptosporidium sp. infections in a large Canadian health region
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Infect Dis 5:72. 2005
    ..This study determined the incidence of and demographic risk factors for developing Giardia sp. and Cryptosporidium sp. infections in a general Canadian population...
  2. ncbi request reprint To close or not to close, that is one of the questions? Perceptions of Trauma Association of Canada surgical members on the management of the open abdomen
    Shahzeer Karmali
    Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 60:287-93. 2006
    ..We sought to evaluate clinical equipoise by surveying Canadian surgeons regarding the use of temporary abdominal closure strategies in damage control and emergency situations...
  3. pmc Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study
    Sean M Bagshaw
    Department of Critical Care Medicine, Calgary Health Region, University of Calgary, Calgary, Alberta, Canada
    Crit Care 9:R700-9. 2005
    ..Severe acute renal failure (sARF) is associated with considerable morbidity, mortality and use of healthcare resources; however, its precise epidemiology and long-term outcomes have not been well described in a non-specified population...
  4. ncbi request reprint Are occult pneumothoraces truly occult or simply missed?
    Chad G Ball
    Department of Surgery, Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 60:294-8 discussion 298-9. 2006
    ..The purpose was to (1) determine whether perceived OPTXs were truly occult or simply missed and (2) address factors that contribute to the poor sensitivity of the supine CXR...
  5. pmc Prospective evaluation of hand-held focused abdominal sonography for trauma (FAST) in blunt abdominal trauma
    Andrew W Kirkpatrick
    Department of Critical Care Medicine, Foothills Medical Centre, Calgary, Alberta
    Can J Surg 48:453-60. 2005
    ..Although hand-held US equipment is now commercially available and may expand the availability and speed of US in assessing the trauma patient, it has not been subjected to controlled evaluation in early trauma care...
  6. ncbi request reprint Incidence, risk factors, and outcomes for occult pneumothoraces in victims of major trauma
    Chad G Ball
    Department of Surgery, Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 59:917-24; discussion 924-5. 2005
    ..Computed tomographic (CT) scanning often detects PTXs that were not diagnosed on CXR (occult PTXs [OPTXs]). The purpose of this study was to define the incidence, predictors, and outcomes for OPTXs after trauma...
  7. pmc Salmonella enterica bacteraemia: a multi-national population-based cohort study
    Kevin B Laupland
    Department of Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada
    BMC Infect Dis 10:95. 2010
    ..However, population-based data are limited. The objective of this study was to define the occurrence of S. enterica bacteremia in a large international population and to evaluate temporal and regional differences...
  8. ncbi request reprint Investigation of sources of potential bias in laboratory surveillance for anti-microbial resistance
    Kevin B Laupland
    Department of Medicine, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    Clin Invest Med 30:E159-66. 2007
    ..Our objective was to evaluate the potential magnitude of bias in reporting of etiologic agents and their resistance rates associated with inclusion of multiple patient samples and non-random timing and location of sampling...
  9. ncbi request reprint One-year mortality of bloodstream infection-associated sepsis and septic shock among patients presenting to a regional critical care system
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, 3535 Research Road NW, Calgary, AB, T2L 2K8, Canada
    Intensive Care Med 31:213-9. 2005
    ....
  10. pmc Population-based laboratory surveillance for AmpC beta-lactamase-producing Escherichia coli, Calgary
    Johann D D Pitout
    University of Calgary, Calgary, Alberta, Canada
    Emerg Infect Dis 13:443-8. 2007
    ..In this large Canadian region, AmpC beta-lactamase-producing E. coli is an emerging community pathogen that commonly causes urinary tract infections in older women...
  11. pmc Intensive care unit-acquired urinary tract infections in a regional critical care system
    Kevin B Laupland
    Department of Critical Care Medicine, Center for Anti microbial Resistance, Calgary Health Region, Calgary Laboratory Services, and University of Calgary, Calgary, Alberta, Canada
    Crit Care 9:R60-5. 2005
    ..The objectives of this study were to describe the occurrence, microbiology, and risk factors for acquiring UTIs in the ICU and to determine whether these infections independently increase mortality...
  12. pmc Molecular epidemiology of metallo-beta-lactamase-producing Pseudomonas aeruginosa in the Calgary Health Region: emergence of VIM-2-producing isolates
    Johann D D Pitout
    Division of Microbiology, Calgary Laboratory Services, 9, 3535 Research Road NW, Calgary, Alberta, Canada T2L 2K8
    J Clin Microbiol 45:294-8. 2007
    ..Our findings suggest that CR and dissemination of MBL clusters among P. aeruginosa populations in large geographic healthcare regions are dynamic processes that require continuous molecular surveillance...
  13. pmc Community-wide outbreaks of clonally related CTX-M-14 beta-lactamase-producing Escherichia coli strains in the Calgary health region
    Johann D D Pitout
    Division of Microbiology, Calgary Laboratory Services, 9 3535 Research Rd NW, Calgary, Alberta T2L 2K8, Canada
    J Clin Microbiol 43:2844-9. 2005
    ..Further studies are warranted to investigate whether community-onset diseases caused by ESBL-producing E. coli are related to a point source or transmission within the community...
  14. doi request reprint Community-onset extended-spectrum beta-lactamase (ESBL) producing Escherichia coli: importance of international travel
    Kevin B Laupland
    Department of Medicine, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    J Infect 57:441-8. 2008
    ..Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli have emerged as significant causes of community-onset disease. We sought to identify risk factors for acquiring community-onset ESBL-producing E. coli...
  15. ncbi request reprint Distribution and determinants of critical illness among status Aboriginal Canadians. A population-based assessment
    Kevin B Laupland
    Department of Critical Care Medicine, Calgary Health Region, University of Calgary, Calgary, Alberta, Canada T2L 2K8
    J Crit Care 21:243-7. 2006
    ..The aim of the study is to determine the incidence, demographic risk factors, and outcomes of critical illness among all adult status Aboriginal Canadians (SACs) admitted to intensive care units (ICUs)...
  16. doi request reprint Epidemiology of Haemophilus influenzae bacteremia: a multi-national population-based assessment
    Kevin B Laupland
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Infect 62:142-8. 2011
    ..Haemophilus influenzae is an important cause of invasive infection but contemporary data in non-selected populations is limited...
  17. ncbi request reprint Severe bloodstream infections: a population-based assessment
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, Calgary Health Region, and Calgary Laboratory Services, Calgary, Alberta, Canada
    Crit Care Med 32:992-7. 2004
    ..We sought to define the incidence and microbiology of severe bloodstream infection (bloodstream infection associated with intensive care unit admission within 48 hrs) and assess risk factors for acquisition and death...
  18. doi request reprint Effect of comorbid illness on the long-term outcome of adults suffering major traumatic injury: a population-based cohort study
    Daniel J Niven
    Department of Critical Care Medicine, University of Calgary and Alberta Health Services, Peter Lougheed Centre, 3500 26th Ave NE, Calgary, Alberta, Canada T1Y 6J4
    Am J Surg 204:151-6. 2012
    ..This study investigated the influence of comorbidities as measured by the Charlson Comorbidity Index (CCI) on the 1-year mortality after major traumatic injury...
  19. doi request reprint Staphylococcus aureus bloodstream infections: risk factors, outcomes, and the influence of methicillin resistance in Calgary, Canada, 2000-2006
    Kevin B Laupland
    Department of Medicine, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    J Infect Dis 198:336-43. 2008
    ..We sought to describe the epidemiological profile of S. aureus bacteremia and to assess whether the incidence and severity of and the antimicrobial resistance rates associated with this bacteremia are increasing...
  20. ncbi request reprint Population-based epidemiological study of infections caused by carbapenem-resistant Pseudomonas aeruginosa in the Calgary Health Region: importance of metallo-beta-lactamase (MBL)-producing strains
    Kevin B Laupland
    Department of Medicine, University of Calgary, Centre for Anti microbial Resistance, and Calgary Health Region, Calgary, Alberta, Canada
    J Infect Dis 192:1606-12. 2005
    ....
  21. doi request reprint Concomitant ceftriaxone and high-concentration intravenous calcium therapy in adult critical care patients: a matched cohort study
    Bruce R Dalton
    Department of Pharmacy Services, Foothills Medical Centre, Alberta Health Services, Calgary, Alberta, Canada
    Ann Pharmacother 44:1158-63. 2010
    ..Systematic population-based data to guide clinicians with respect to this risk are, however, lacking...
  22. pmc Molecular epidemiology of CTX-M-producing Escherichia coli in the Calgary Health Region: emergence of CTX-M-15-producing isolates
    Johann D D Pitout
    Calgary Laboratory Services, Department of Pathology and Laboratory Medicine, University of Calgary, 9, 3535 Research Road NW, Calgary, Alberta, Canada T2L 2K8
    Antimicrob Agents Chemother 51:1281-6. 2007
    ..This study illustrates the importance of molecular surveillance in tracking CTX-M-producing E. coli strains in the community and investigating their influx into hospitals...
  23. pmc Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill
    Houman Khosravani
    Department of Critical Care Medicine, University of Calgary, Calgary, Alberta T2N 2T9, Canada
    Crit Care 13:R90. 2009
    ..We sought to determine the occurrence and relation of hyperlactatemia with ICU mortality in all patients admitted to four ICUs in a large regional critical care system...
  24. ncbi request reprint Non-neurologic organ dysfunction in severe traumatic brain injury
    David A Zygun
    Departments of Critical Care Medicine, University of Calgary, Calgary Alberta, Canada
    Crit Care Med 33:654-60. 2005
    ..To describe the incidence of non-neurologic organ dysfunction and its association with outcome in patients with severe traumatic brain injury admitted to intensive care...
  25. doi request reprint Antimicrobial susceptibility of well-characterised multiresistant CTX-M-producing Escherichia coli: failure of automated systems to detect resistance to piperacillin/tazobactam
    Johann D D Pitout
    Division of Microbiology, Calgary Laboratory Services, Calgary, Alberta, Canada
    Int J Antimicrob Agents 32:333-8. 2008
    ..coli. We recommend that laboratories using Vitek should employ alternative susceptibility testing methods for TZP before reporting the activity of this agent against ESBL-producing E. coli...
  26. pmc Population-based epidemiology of intensive care: critical importance of ascertainment of residency status
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, Calgary Health Region, and Calgary Laboratory Services, Calgary, Alberta, Canada
    Crit Care 8:R431-6. 2004
    ..The objective of this study was to evaluate the potential effects of inclusion of nonresidents in population-based studies in intensive care...
  27. ncbi request reprint Invasive Candida species infections: a 5 year population-based assessment
    Kevin B Laupland
    Department of Medicine, Calgary Health Region and University of Calgary, Calgary, Alberta, Canada
    J Antimicrob Chemother 56:532-7. 2005
    ..The objective of this study was to define the occurrence of, risk factors for, and antifungal susceptibilities of invasive Candida species infections in a large Canadian health region...
  28. ncbi request reprint One-year mortality in critically ill patients by severity of kidney dysfunction: a population-based assessment
    Sean M Bagshaw
    Department of Critical Care Medicine, Calgary Health Region and University of Calgary, Alberta, Canada
    Am J Kidney Dis 48:402-9. 2006
    ..Kidney dysfunction in the intensive care unit (ICU) results in increased morbidity, mortality, and health care costs; however, long-term mortality has not been described across strata of severity in kidney dysfunction...
  29. ncbi request reprint Adequacy of empirical antifungal therapy and effect on outcome among patients with invasive Candida species infections
    Michael D Parkins
    Department of Medicine, Calgary Health Region and University of Calgary, Calgary, Alberta, Canada
    J Antimicrob Chemother 60:613-8. 2007
    ..We sought to assess the adequacy of empirical therapy and its effect on mortality in invasive Candida species infections...
  30. doi request reprint Risk of bloodstream infection in patients with chronic kidney disease not treated with dialysis
    Matthew T James
    Department of Medicine, University of Calgary, Foothills Medical Center, 1403 29th St NW, Calgary, AB T2N 2T9, Canada
    Arch Intern Med 168:2333-9. 2008
    ..Whether patients with chronic kidney disease who are not receiving dialysis are also at increased risk of bloodstream infection is less clear...
  31. doi request reprint Epidemiology of Staphylococcus aureus nasal colonization and influence on outcome in the critically ill
    Daniel J Niven
    Department of Medicine, University of Calgary, Calgary Health Region, and Calgary Laboratory Services, Calgary, Alberta, Canada
    J Crit Care 24:583-9. 2009
    ..To determine the rate of Staphylococcus aureus nasal colonization at admission to intensive care units (ICU) and assess its effect on the development of an ICU-acquired S aureus infection...
  32. doi request reprint A population-based study of pyogenic liver abscesses in the United States: incidence, mortality, and temporal trends
    Liisa Meddings
    Department of Medicine, University of Calgary, Alberta, Canada
    Am J Gastroenterol 105:117-24. 2010
    ..Few population-based studies have evaluated pyogenic liver abscess (PLA) in North America. We assessed the incidence of PLA and evaluated predictors of mortality...
  33. ncbi request reprint Population-based assessment of intensive care unit-acquired bloodstream infections in adults: Incidence, risk factors, and associated mortality rate
    Kevin B Laupland
    Division of Critical Care Medicine, University of Calgary, Calgary Health Region, Alberta, Canada
    Crit Care Med 30:2462-7. 2002
    ..The study objective was to define the incidence, risk factors, microbiology, and clinical outcomes of intensive care unit-acquired bloodstream infections...
  34. pmc Dialysis Disequilibrium Syndrome: brain death following hemodialysis for metabolic acidosis and acute renal failure--a case report
    Sean M Bagshaw
    Department of Critical Care Medicine, Calgary Health Region, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 5:9. 2004
    ..We describe a case of DDS-induced cerebral edema that resulted in irreversible brain injury and death following acute HD and review the relevant literature of the association of DDS and HD...
  35. doi request reprint A cohort study of nutrition practices in the intensive care unit following abdominal aortic aneurysm repair
    Melanie R Ksienski
    Department of Nutrition Services, Alberta Health Services, Calgary, Alberta, Canada
    JPEN J Parenter Enteral Nutr 37:261-7. 2013
    ....
  36. doi request reprint Can cervical spine computed tomography assist in detecting occult pneumothoraces?
    Chad G Ball
    Department of Surgery, The University of Calgary, Trauma Services Foothills Medical Centre, 1403 29 Street N W, T2N 2T9 Calgary, Alberta, Canada
    Injury 43:51-4. 2012
    ..Because abdominal CT imaging misses OPTXs in the upper thorax, the objective of this study was to evaluate the utility of cervical spine (C-spine) CT screening for diagnosing OPTXs...
  37. ncbi request reprint Clostridium perfringens pleuropulmonary infection and septic shock: case report and population-based laboratory surveillance study
    Shannon Jackson
    Department of Medicine, Calgary Laboratory Services, University of Calgary, and the Calgary Health Region, Calgary, Alberta, Canada
    Scand J Infect Dis 35:883-6. 2003
    ..Population-based laboratory surveillance was subsequently conducted that identified an annual incidence of invasive C. perfringens disease of 0.83 per 100,000 population with a striking age-related increased risk for acquisition...
  38. ncbi request reprint Severe traumatic brain injury in a large Canadian health region
    David A Zygun
    Department of Critical Care Medicine, University of Calgary and the Calgary Health Region, Calgary, AB Canada
    Can J Neurol Sci 32:87-92. 2005
    ..We sought to define the incidence, risk factors and outcome of patients suffering sTBI in a large Canadian region...
  39. pmc Molecular characteristics of extended-spectrum-beta-lactamase-producing Escherichia coli isolates causing bacteremia in the Calgary Health Region from 2000 to 2007: emergence of clone ST131 as a cause of community-acquired infections
    Johann D D Pitout
    Division of Microbiology, Calgary Laboratory Services, 9, 3535 Research Road NW, Calgary, Alberta, Canada
    Antimicrob Agents Chemother 53:2846-51. 2009
    ..coli isolates; and this is the first study to identify CTX-M-14 in E. coli clone ST131...
  40. doi request reprint The changing burden of pediatric bloodstream infections in Calgary, Canada, 2000-2006
    Kevin B Laupland
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Pediatr Infect Dis J 28:114-7. 2009
    ....
  41. ncbi request reprint Long-term mortality outcome associated with prolonged admission to the ICU
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary and Calgary Health Region, Calgary, AB, Canada
    Chest 129:954-9. 2006
    ..The objective of this study was to describe the occurrence and factors predictive of prolonged ICU stay at admission, and to define the long-term (>/= 1 year) mortality outcome...
  42. doi request reprint Hospital mortality among adults admitted to and discharged from intensive care on weekends and evenings
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    J Crit Care 23:317-24. 2008
    ..Patient care may be inconsistent during off hours. We sought to determine whether adults admitted to or discharged from intensive care units (ICUs) on evenings and weekends have increased mortality rates...
  43. doi request reprint Use of near-infrared spectroscopy as a physiologic monitor for intra-abdominal hypertension
    Sandy Widder
    Regional Trauma Services, Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 64:1165-8. 2008
    ..We sought to examine whether NIRS measurement of the AW was safe, and correlated with intra-abdominal pressure (IAP) in ICU patients...
  44. ncbi request reprint Population-based laboratory surveillance for Escherichia coli-producing extended-spectrum beta-lactamases: importance of community isolates with blaCTX-M genes
    Johann D D Pitout
    Department of Pathology and Laboratory Medicine, University of Calgary, Calgary Laboratory Services, and the Centre for Antimicrobial Resistance, Calgary, Alberta, Canada
    Clin Infect Dis 38:1736-41. 2004
    ..2; 95% confidence interval, 3.69-54.84). Strains of E. coli with blaCTX-M genes commonly cause community-onset infections, and women and older patients are at highest risk...
  45. doi request reprint Molecular epidemiology of extended-spectrum-β-lactamase-producing Klebsiella pneumoniae over a 10 year period in Calgary, Canada
    Gisele Peirano
    Division of Microbiology, Calgary Laboratory Services, Calgary, Alberta, Canada
    J Antimicrob Chemother 67:1114-20. 2012
    ..A study was designed to investigate the molecular epidemiology of extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae isolated in a centralized region over a 10 year period (2000-09)...
  46. ncbi request reprint Validation of a rapid diagnostic strategy for determination of significant bacterial counts in bronchoalveolar lavage samples
    Kevin B Laupland
    Department of Critical Care Medicine, Centre for Antimicrobial Resistance, University of Calgary, Alberta, Canada
    Arch Pathol Lab Med 129:78-81. 2005
    ..We developed a rapid diagnostic testing strategy that is highly sensitive for screening bacteria in bronchoalveolar lavage (BAL) samples, with results available within hours of collection...
  47. pmc Molecular characteristics of travel-related extended-spectrum-beta-lactamase-producing Escherichia coli isolates from the Calgary Health Region
    Johann D D Pitout
    Division of Microbiology, Calgary Laboratory Services, University of Calgary, Calgary, Alberta, Canada
    Antimicrob Agents Chemother 53:2539-43. 2009
    ..Our study suggested that clone ST131 coproducing CTX-M-15, OXA-1, TEM-1, and AAC(6')-Ib-cr and clonally unrelated CTX-M-14 producers have emerged as important causes of community-acquired, travel-related infections...
  48. ncbi request reprint Polyclonal intravenous immunoglobulin for the treatment of severe sepsis and septic shock in critically ill adults: a systematic review and meta-analysis
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, Calgary, AB, Canada
    Crit Care Med 35:2686-92. 2007
    ..To systematically review the literature to assess whether adjunctive therapy with polyclonal intravenous immunoglobulin (ivIg) reduces mortality among critically ill adults with severe sepsis and septic shock...
  49. doi request reprint Extended-spectrum beta-lactamase-producing Enterobacteriaceae: an emerging public-health concern
    Johann D D Pitout
    Division of Microbiology, Calgary Laboratory Services, Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada
    Lancet Infect Dis 8:159-66. 2008
    ..Thus, more rapid diagnostic testing of ESBL-producing bacteria and the possible modification of guidelines for community-onset bacteraemia associated with UTIs are required...
  50. ncbi request reprint Limited ability of SOFA and MOD scores to discriminate outcome: a prospective evaluation in 1,436 patients
    David A Zygun
    Department of Critical Care Medicine, University of Calgary, Foothills Medical Centre, 1403 29th Street, NW, Calgary, Alberta T2N 2T9, Canada
    Can J Anaesth 52:302-8. 2005
    ..We sought to compare the performance of the SOFA and MOD scores in a large cohort of consecutive multisystem intensive care unit (ICU) patients...
  51. doi request reprint Long-term mortality outcome of victims of major trauma
    Kevin B Laupland
    Department of Medicine, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    Injury 41:69-72. 2010
    ..Although trauma is associated with major acute morbidity and mortality, its long-term outcome is less well defined. We sought to define the rate of readmission to hospital and long-term mortality of victims of major trauma...
  52. doi request reprint Incidence, risk factors, and outcomes of Klebsiella pneumoniae bacteremia
    Bonnie L Meatherall
    Department of Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada
    Am J Med 122:866-73. 2009
    ..We sought to describe the incidence of, risk factors for, and outcomes associated with K. pneumoniae bacteremia...
  53. pmc Population-based study of severe trauma due to electrocution in the Calgary Health Region, 1996-2002
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary and the Calgary Health Region, Calgary, Alberta
    Can J Surg 48:289-92. 2005
    ..We therefore studied an active population of adult victims of severe electrical trauma in a large area of Canada (the Calgary Health Region [CHR])...
  54. doi request reprint Development of a novel electronic surveillance system for monitoring of bloodstream infections
    Jenine Leal
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Infect Control Hosp Epidemiol 31:740-7. 2010
    ..Electronic surveillance systems (ESSs) that utilize existing information in databases are more efficient than conventional infection surveillance methods...
  55. doi request reprint Time to blood culture positivity in Staphylococcus aureus bacteremia: association with 30-day mortality
    Joseph Kim
    Division of Infectious Diseases, University of Calgary, 3500 26 Avenue NE, Calgary, AB, Canada T1Y 6J4
    J Infect 61:197-204. 2010
    ..This study describes the relationship between TTP and clinical outcome in all patients with Staphylococcus aureus bacteremia (SAB) in a large Canadian health region...
  56. ncbi request reprint Renal arterial resistive index response to intraabdominal hypertension in a porcine model
    Andrew W Kirkpatrick
    Department of Surgery, Foothills Medical Centre, Calgary, Alberta, Canada
    Crit Care Med 35:207-13. 2007
    ....
  57. ncbi request reprint Factors related to the failure of radiographic recognition of occult posttraumatic pneumothoraces
    Chad G Ball
    Department of Surgery, Foothills Medical Centre, Room EG23, 1403 29 Street NW, Calgary, Alberta, Canada
    Am J Surg 189:541-6; discussion 546. 2005
    ..Computed tomography (CT) often identifies occult pneumothoraces (OPTXs). Previous descriptions of OPTX topography have been poor. Our purpose was to define their distribution and aid in the targeting of thoracic ultrasound...
  58. ncbi request reprint A population-based assessment of major trauma in a large Canadian region
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary and the Calgary Health Region, Calgary, Alberta, Canada
    Am J Surg 189:571-5; discussion 576. 2005
    ..The cause of major trauma has not been well defined using population-based methodologies...
  59. doi request reprint Fever in the critically ill: a review of epidemiology, immunology, and management
    Daniel J Niven
    Department of Critical Care Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada
    J Intensive Care Med 27:290-7. 2012
    ..As such, a review of the epidemiology, molecular mechanisms, and immunology of fever as well as the evidence behind management of fever in the critically ill is pertinent to all critical care practitioners...
  60. pmc The distinct category of healthcare associated bloodstream infections
    Ryan Lenz
    Department of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada
    BMC Infect Dis 12:85. 2012
    ..However, a third category of healthcare-associated (HCA) community onset disease has been increasingly recognized. The objective of this study was to compare and contrast characteristics of HCA-BSI with CA-BSI and HA-BSI...
  61. doi request reprint Colonization of returning travelers with CTX-M-producing Escherichia coli
    Gisele Peirano
    Division of Microbiology, Calgary Laboratory Services, University of Calgary, Calgary, Alberta, Canada
    J Travel Med 18:299-303. 2011
    ....
  62. doi request reprint CKD and risk of hospitalization and death with pneumonia
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Kidney Dis 54:24-32. 2009
    ..The objective of this study is to determine the associations between estimated glomerular filtration rate (eGFR) and hospitalization or death with pneumonia...
  63. ncbi request reprint Intravenous immunoglobulin for severe infections: a survey of Canadian specialists
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary, and Calgary Health Region, Calgary, Alberta, Canada
    J Crit Care 19:75-81. 2004
    ..To survey the opinions of Canadian critical care medicine and infectious disease specialists about the use of intravenous immunoglobulin (IVIG) for the treatment of severe infections...
  64. ncbi request reprint Spill your guts! Perceptions of Trauma Association of Canada member surgeons regarding the open abdomen and the abdominal compartment syndrome
    Andrew W Kirkpatrick
    Department of Medicine, Foothills Medical Centre, Calgary, Alberta, Canada
    J Trauma 60:279-86. 2006
    ..To survey surgeon opinion regarding the management of the open abdomen (OA) and abdominal compartment syndrome (ACS) to assess current practice and direct future prospective clinical studies...
  65. ncbi request reprint Isolation of Candida species from critically ill patients
    Kevin B Laupland
    Department of Critical Care Medicine, Calgary Health Region, University of Calgary, Calgary, Alberta, Canada T2N 2T5
    J Crit Care 22:250-1. 2007
  66. ncbi request reprint Ventilator-associated pneumonia in severe traumatic brain injury
    David A Zygun
    Department of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada
    Neurocrit Care 5:108-14. 2006
    ..An additional goal was to define the relationship of ventilator-associated pneumonia (VAP) with nonneurological organ dysfunction...
  67. ncbi request reprint Characteristics and conviction rates of injured alcohol-impaired drivers admitted to a tertiary care Canadian Trauma Centre
    Michelle E Goecke
    Departments of Surgery, University of Calgary, Calgary, Alberta, Canada
    Clin Invest Med 30:26-32. 2007
    ..Despite greater societal attention, medical admission after MVC results in avoidance of legal consequences. We sought to determine characteristics of, and consequences to, injured alcohol-impaired drivers (IAIDs)...
  68. doi request reprint Severe community-acquired pneumonia in adults: current antimicrobial chemotherapy
    Daniel J Niven
    Department of Medicine, University of Calgary, and Calgary Health Region, Calgary, AB, Canada
    Expert Rev Anti Infect Ther 7:69-81. 2009
    ..There is limited evidence to guide the use of specific drugs, multidrug effective regimens and the duration of therapy, and an individualized approach is needed...
  69. ncbi request reprint Epidemiology of intensive care unit-acquired urinary tract infections
    Sean M Bagshaw
    Department of Critical Care Medicine, Calgary Laboratory Services, Calgary Health Region, and University of Calgary, Calgary, Alberta, Canada
    Curr Opin Infect Dis 19:67-71. 2006
    ..We review the occurrence, microbiology, risk factors for acquisition, and outcomes associated with intensive care unit-acquired urinary tract infections...
  70. ncbi request reprint Is regional citrate superior to systemic heparin anticoagulation for continuous renal replacement therapy? A prospective observational study in an adult regional critical care system
    Sean M Bagshaw
    Department of Critical Care Medicine, University of Calgary and Calgary Health Region, Foothills Medical Centre, Alberta, Canada
    J Crit Care 20:155-61. 2005
    ..We report our regional CRRT protocol that was developed using the principles of quality improvement and compare the effect of regional citrate with systemic heparin anticoagulation on filter life span...
  71. pmc Virulence factors of Escherichia coli isolates that produce CTX-M-type extended-spectrum beta-lactamases
    Johann D D Pitout
    Department of Pathology and Laboratory Medicine, University of Calgary, Alberta, Canada
    Antimicrob Agents Chemother 49:4667-70. 2005
    ..Our results indicate that CTX-M type predicts phylogenetic background, and the virulence potential of ESBL-producing E. coli isolates is a complex issue, requiring further study and ongoing surveillance...
  72. ncbi request reprint Emergence of Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBLs) in the community
    Johann D D Pitout
    Division of Microbiology, Calgary Laboratory Services, Alberta, Canada
    J Antimicrob Chemother 56:52-9. 2005
    ....
  73. ncbi request reprint Emerging gram-positive bacterial infections
    Sameer Elsayed
    Department of Pathology and Laboratory Medicine, University of Calgary, 9, 3535 Research Road NW, Calgary, Alberta T2L 2K8, Canada
    Clin Lab Med 24:587-603, v. 2004
    ..This review focuses on the clinical and microbiologic aspects of key emerging infections caused by this group of microorganisms...
  74. ncbi request reprint Incidence and risk factors for acquiring nosocomial urinary tract infection in the critically ill
    Kevin B Laupland
    Division of Critical Care Medicine, University of Calgary, Calgary Health Region, Canada
    J Crit Care 17:50-7. 2002
    ..However, the epidemiology of intensive care unit (ICU)-acquired UTIs is not well defined. The objective of this study was to describe the incidence, risk factors, and clinical outcomes of ICU-acquired UTIs...
  75. ncbi request reprint Population-based study of the epidemiology of and the risk factors for pyogenic liver abscess
    Gilaad G Kaplan
    Department of Medicine, University of Calgary, Calgary Health Region, Alberta, Canada
    Clin Gastroenterol Hepatol 2:1032-8. 2004
    ..Our objective was to characterize the incidence of, risk factors for, and outcomes of PLA in a nonselected population...
  76. ncbi request reprint Population-based study of the epidemiology of and the risk factors for invasive Staphylococcus aureus infections
    Kevin B Laupland
    Department of Medicine, University of Calgary, Calgary Health Region, Calgary, Canada
    J Infect Dis 187:1452-9. 2003
    ..This study provides important data on the burden of ISA disease and identifies risk groups that may potentially benefit from preventive efforts...
  77. ncbi request reprint The burden of large and small duct primary sclerosing cholangitis in adults and children: a population-based analysis
    Gilaad G Kaplan
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Gastroenterol 102:1042-9. 2007
    ....
  78. ncbi request reprint Economic evaluation in critical care medicine
    Heather L Cox
    Department of Surgery, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada T2L 2K8
    J Crit Care 21:117-24. 2006
    ..This article highlights the need for randomized clinical trials and economic evaluations of therapies in critical care medicine for which the effect of the therapy on health outcomes and/or costs are unknown...
  79. ncbi request reprint A rare case of pleuropulmonary infection and septic shock associated with Enterococcus faecium endocarditis
    Paul MacEachern
    Department of Medicine, University of Calgary, Calgary, Alta, Canada
    J Infect 50:84-8. 2005
    ..Enterococci rarely cause pleuropulmonary infections. A novel case of definitively diagnosed nosocomial Enterococcus faecium pneumonia, empyema, and endocarditis associated with septic shock is reported...
  80. pmc Blood cultures in ambulatory outpatients
    Kevin B Laupland
    Department of Medicine, Centre for Anti microbial Resistance and Infectious Diseases Research Group, University of Calgary, Calgary Health Region, and Calgary Laboratory Services, Calgary, Alberta, Canada
    BMC Infect Dis 5:35. 2005
    ..However, the low yield may limit their usefulness, particularly in low-risk populations. This study was conducted to assess the utility of blood cultures drawn from ambulatory outpatients...
  81. pmc A potentially preventable case of serious influenza infection in a pregnant patient
    Michael D Parkins
    Department of Medicine, University of Calgary, and Calgary Health Region, Calgary, Alta
    CMAJ 177:851-3. 2007
  82. pmc Development of a Health-Related Quality of Life Questionnaire (HRQL) for patients with Extremity Soft Tissue Infections (ESTI)
    Aric J Storck
    Department of Emergency Medicine, Calgary Health Region, Calgary, Alberta, Canada
    BMC Infect Dis 6:148. 2006
    ..The objective of this study was to develop a health-related quality of life questionnaire (HRQL) for patients with extremity soft tissue infections (ESTI) for future use in clinical trials...
  83. ncbi request reprint Treatment of Staphylococcus aureus colonization and prophylaxis for infection with topical intranasal mupirocin: an evidence-based review
    Kevin B Laupland
    Department of Medicine, University of Calgary and the Calgary Health Region, Calgary, Alberta, Canada
    Clin Infect Dis 37:933-8. 2003
    ..Although mupirocin is effective at reducing nasal carriage, routine use of topical intranasal mupirocin for infection prophylaxis is not supported by the currently available evidence...
  84. ncbi request reprint Evaluation of a rapid bacterial ATP assay for screening BAL samples from ICU patients submitted for quantitative bacterial cultures
    Kevin B Laupland
    Department of Critical Care Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada
    Diagn Microbiol Infect Dis 47:465-9. 2003
    ..A combined negative rapid test consisting of Gram's stain/bacterial ATP assay rules out significant bacteria in BAL samples with a high degree of certainty. Future studies are needed to clinically validate these observations...
  85. pmc Population-based laboratory surveillance of Hafnia alvei isolates in a large Canadian health region
    Kevin B Laupland
    Department of Medicine, University of Calgary and Calgary Health Region, Calgary Alberta, Canada
    Ann Clin Microbiol Antimicrob 5:12. 2006
    ..Hospital-based series have characterized Hafnia alvei primarily as an infrequent agent of polymicrobial nosocomial infections in males with underlying illness...
  86. ncbi request reprint Outpatient parenteral antibiotic therapy: evolution of the Calgary adult home parenteral therapy program
    Kevin B Laupland
    Department of Medicine, University of Calgary, Alta
    Clin Invest Med 25:185-90. 2002
    ....