R A Lanius

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. pmc Effect of direct eye contact in PTSD related to interpersonal trauma: an fMRI study of activation of an innate alarm system
    Carolin Steuwe
    LHSC UH, 339 Windermere Road, PO Box 5339, London, Ontario, Canada N6A 5A5
    Soc Cogn Affect Neurosci 9:88-97. 2014
  2. doi How understanding the neurobiology of complex post-traumatic stress disorder can inform clinical practice: a social cognitive and affective neuroscience approach
    R A Lanius
    Department of Psychiatry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada
    Acta Psychiatr Scand 124:331-48. 2011
  3. pmc Does neuroimaging research examining the pathophysiology of posttraumatic stress disorder require medication-free patients?
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Ont, Canada
    J Psychiatry Neurosci 35:80-9. 2010
  4. doi Default mode network connectivity as a predictor of post-traumatic stress disorder symptom severity in acutely traumatized subjects
    R A Lanius
    Department of Psychiatry, The University of Western Ontario, London, ON, Canada
    Acta Psychiatr Scand 121:33-40. 2010
  5. ncbi Neural correlates of traumatic memories in posttraumatic stress disorder: a functional MRI investigation
    R A Lanius
    Department of Psychiatry, University of Western Ontario, London, Canada
    Am J Psychiatry 158:1920-2. 2001
  6. ncbi Neural correlates of trauma script-imagery in posttraumatic stress disorder with and without comorbid major depression: a functional MRI investigation
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
    Psychiatry Res 155:45-56. 2007
  7. ncbi A review of neuroimaging studies in PTSD: heterogeneity of response to symptom provocation
    R A Lanius
    Department of Psychiatry, London Health Sciences Centre, University of Western Ontario, 339 Windermere Road, P O Box 5339, London, Ont, Canada N6A 5A5
    J Psychiatr Res 40:709-29. 2006
  8. ncbi Individual differences in a husband and wife who developed PTSD after a motor vehicle accident: a functional MRI case study
    Ruth A Lanius
    Department of Psychiatry, Medical Biophysics, University of Western Ontario, London, Canada
    Am J Psychiatry 160:667-9. 2003
  9. ncbi The nature of traumatic memories: a 4-T FMRI functional connectivity analysis
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Canada
    Am J Psychiatry 161:36-44. 2004
  10. ncbi Functional connectivity of dissociative responses in posttraumatic stress disorder: a functional magnetic resonance imaging investigation
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
    Biol Psychiatry 57:873-84. 2005

Detail Information

Publications29

  1. pmc Effect of direct eye contact in PTSD related to interpersonal trauma: an fMRI study of activation of an innate alarm system
    Carolin Steuwe
    LHSC UH, 339 Windermere Road, PO Box 5339, London, Ontario, Canada N6A 5A5
    Soc Cogn Affect Neurosci 9:88-97. 2014
    ..In individuals with PTSD, however, direct gaze leads to sustained activation of a subcortical route of eye-contact processing, an innate alarm system involving the SC and the underlying circuits of the PAG. ..
  2. doi How understanding the neurobiology of complex post-traumatic stress disorder can inform clinical practice: a social cognitive and affective neuroscience approach
    R A Lanius
    Department of Psychiatry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada
    Acta Psychiatr Scand 124:331-48. 2011
    ....
  3. pmc Does neuroimaging research examining the pathophysiology of posttraumatic stress disorder require medication-free patients?
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Ont, Canada
    J Psychiatry Neurosci 35:80-9. 2010
    ..The evidence for potentially confounding effects of psychotherapy in PTSD are also discussed...
  4. doi Default mode network connectivity as a predictor of post-traumatic stress disorder symptom severity in acutely traumatized subjects
    R A Lanius
    Department of Psychiatry, The University of Western Ontario, London, ON, Canada
    Acta Psychiatr Scand 121:33-40. 2010
    ..The goal of this study was to investigate the relationship between default mode network connectivity and the severity of post-traumatic stress disorder (PTSD) symptoms in a sample of eleven acutely traumatized subjects...
  5. ncbi Neural correlates of traumatic memories in posttraumatic stress disorder: a functional MRI investigation
    R A Lanius
    Department of Psychiatry, University of Western Ontario, London, Canada
    Am J Psychiatry 158:1920-2. 2001
    ..The neuronal circuitry underlying posttraumatic stress disorder (PTSD) was studied in traumatized subjects with and without PTSD...
  6. ncbi Neural correlates of trauma script-imagery in posttraumatic stress disorder with and without comorbid major depression: a functional MRI investigation
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
    Psychiatry Res 155:45-56. 2007
    ..These results suggest different patterns of brain activation related to comorbid major depression occurring in the context of PTSD...
  7. ncbi A review of neuroimaging studies in PTSD: heterogeneity of response to symptom provocation
    R A Lanius
    Department of Psychiatry, London Health Sciences Centre, University of Western Ontario, 339 Windermere Road, P O Box 5339, London, Ont, Canada N6A 5A5
    J Psychiatr Res 40:709-29. 2006
    ..This review will integrate findings of different experiential, psychophysiological, and neurobiological responses to traumatic symptom provocation with the clinical symptomatology and the neurobiology of PTSD...
  8. ncbi Individual differences in a husband and wife who developed PTSD after a motor vehicle accident: a functional MRI case study
    Ruth A Lanius
    Department of Psychiatry, Medical Biophysics, University of Western Ontario, London, Canada
    Am J Psychiatry 160:667-9. 2003
  9. ncbi The nature of traumatic memories: a 4-T FMRI functional connectivity analysis
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Canada
    Am J Psychiatry 161:36-44. 2004
    ..This study used functional connectivity analyses to assess interregional brain activity correlations during the recall of traumatic memories in traumatized subjects with and without posttraumatic stress disorder (PTSD)...
  10. ncbi Functional connectivity of dissociative responses in posttraumatic stress disorder: a functional magnetic resonance imaging investigation
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
    Biol Psychiatry 57:873-84. 2005
    ..The purpose of this study was to assess interregional brain activity covariations during traumatic script-driven imagery in subjects with posttraumatic stress disorder (PTSD)...
  11. ncbi Brain activation during script-driven imagery induced dissociative responses in PTSD: a functional magnetic resonance imaging investigation
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
    Biol Psychiatry 52:305-11. 2002
    ..The other 30% of patients had a dissociative response with no concomitant increase in heart rate. This article focuses on the latter group...
  12. ncbi Alexithymia in PTSD: psychometric and FMRI studies
    Paul A Frewen
    London Health Sciences Centre, 339 Windermere Road, PO Box 5339, London, Ontario, Canada, N6A 5A5
    Ann N Y Acad Sci 1071:397-400. 2006
    ..In 26 individuals with PTSD, TAS-20 scores correlated positively with response in insula, posterior cingulate cortex (PCC), and thalamus, and negatively with response in ACC...
  13. ncbi Recall of emotional states in posttraumatic stress disorder: an fMRI investigation
    Ruth A Lanius
    Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
    Biol Psychiatry 53:204-10. 2003
    ....
  14. pmc Switching between executive and default mode networks in posttraumatic stress disorder: alterations in functional connectivity
    Judith K Daniels
    Department of Psychiatry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ont, Canada
    J Psychiatry Neurosci 35:258-66. 2010
    ....
  15. doi Neural correlates of self-reflection in post-traumatic stress disorder
    R L Bluhm
    Department of Philosophy and Religious Studies, Old Dominion University, Norfolk, VA, USA
    Acta Psychiatr Scand 125:238-46. 2012
    ..We hypothesized that individuals with PTSD would differ from controls in functional activation of the MPFC and PCC during SRP...
  16. pmc Emotion modulation in PTSD: Clinical and neurobiological evidence for a dissociative subtype
    Ruth A Lanius
    Department of Psychiatry, The University of Western Ontario, London, Canada
    Am J Psychiatry 167:640-7. 2010
    ..These findings have important implications for treatment of PTSD, including the need to assess patients with PTSD for dissociative symptoms and to incorporate the treatment of dissociative symptoms into stage-oriented trauma treatment...
  17. doi Cognitive distortions in an acutely traumatized sample: an investigation of predictive power and neural correlates
    J K Daniels
    Department of Psychiatry, The University of Western Ontario, University Hospital, London, Ontario, Canada
    Psychol Med 41:2149-57. 2011
    ..Previous studies have shown that cognitive distortions in the early aftermath of traumatic events can predict future PTSD severity but, to date, no studies have investigated the neural correlates of this association...
  18. pmc Spontaneous low-frequency fluctuations in the BOLD signal in schizophrenic patients: anomalies in the default network
    Robyn L Bluhm
    Department of Psychiatry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada
    Schizophr Bull 33:1004-12. 2007
    ..Because these data suggest significant abnormalities in resting-state neural networks in schizophrenia, further investigations of spontaneous slow fluctuations of the BOLD signal seem warranted in this population...
  19. doi Meta-analysis of alexithymia in posttraumatic stress disorder
    Paul A Frewen
    Department of Psychology, The University of Western Ontario, Ontario, Canada
    J Trauma Stress 21:243-6. 2008
    ..A large effect size was found associating PTSD with alexithymia. Effect sizes were higher in studies of male combat PTSD samples in comparison with studies of other PTSD samples. Clinical and research directions are discussed...
  20. ncbi Toward a psychobiology of posttraumatic self-dysregulation: reexperiencing, hyperarousal, dissociation, and emotional numbing
    Paul A Frewen
    Department of Psychology, The University of Western Ontario UWO, N6A 5C2 London, Ontario, Canada
    Ann N Y Acad Sci 1071:110-24. 2006
    ..We conclude by discussing the clinical significance of this framework for psychological assessment and treatment of posttrauma psychopathology...
  21. doi Default mode network connectivity: effects of age, sex, and analytic approach
    Robyn L Bluhm
    Department of Psychiatry, Schulich School of Medicine and Dentistry, Canada
    Neuroreport 19:887-91. 2008
    ..Age and sex differences were small and there was less agreement between analytic techniques regarding age and sex effects than regarding default mode network structure...
  22. ncbi Neuroimaging studies of psychological interventions for mood and anxiety disorders: empirical and methodological review
    Paul A Frewen
    Department of Psychology, The University of Western Ontario, Canada
    Clin Psychol Rev 28:228-46. 2008
    ..Specific recommendations for future studies are outlined, and the clinical and theoretical significance of this research is discussed...
  23. doi Clinical and neural correlates of alexithymia in posttraumatic stress disorder
    Paul A Frewen
    Department of Psychology, University of Western Ontario, London, Ontario, Canada
    J Abnorm Psychol 117:171-81. 2008
    ..Clinical and theoretical implications and future research directions are discussed...
  24. ncbi Neurobiology of dissociation: unity and disunity in mind-body-brain
    Paul A Frewen
    Department of Psychology, The University of Western Ontario, 339 Windermere Road, P O Box 5339, London, Ontario N6A 5A5, Canada
    Psychiatr Clin North Am 29:113-28, ix. 2006
  25. ncbi Psychologic trauma, posttraumatic stress disorder, and dermatology
    Madhulika A Gupta
    Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
    Dermatol Clin 23:649-56. 2005
    ....
  26. ncbi Neural correlates of reexperiencing, avoidance, and dissociation in PTSD: symptom dimensions and emotion dysregulation in responses to script-driven trauma imagery
    James W Hopper
    Behavioral Psychopharmacology Research Laboratory, Department of Psychiatry, Harvard Medical School and McLean Hospital, Belmont, MA 02478, USA
    J Trauma Stress 20:713-25. 2007
    ..Theoretical and clinical implications are discussed, particularly with respect to an emotion-dysregulation account of PTSD...
  27. ncbi Functional magnetic resonance imaging: application to posttraumatic stress disorder
    Katherine H Taber
    Department of Radiology, Baylor College of Medicine, Houston, Texas 77030 3498, USA
    J Neuropsychiatry Clin Neurosci 15:125-9. 2003
  28. ncbi Stage-oriented trauma treatment using dialectical behaviour therapy
    Ruth A Lanius
    Can J Psychiatry 48:126-7. 2003