Angela B Lange

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Evidence for crustacean cardioactive peptide-like innervation of the gut in Locusta migratoria
    Andrew Donini
    Department of Zoology, University of Toronto at Mississauga, 3359, Mississauga Road, North Mississauga, Ont, Canada L5L 1C6
    Peptides 23:1915-23. 2002
  2. ncbi request reprint Dopaminergic control of foregut contractions in Locusta migratoria
    Angela B Lange
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ont, Canada L5L 1C6
    J Insect Physiol 54:222-30. 2008
  3. ncbi request reprint The presence and distribution of crustacean cardioactive peptide in the central and peripheral nervous system of the stick insect, Baculum extradentatum
    Angela B Lange
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Rd, Mississauga, ON, Canada L5L 1C6
    Regul Pept 129:191-201. 2005
  4. ncbi request reprint Neural and hormonal control of muscular activity of the spermatheca in the locust, Locusta migratoria
    Angela B Lange
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario L5L 1C6, Canada
    Peptides 28:174-84. 2007
  5. ncbi request reprint A review of the involvement of proctolin as a cotransmitter and local neurohormone in the oviduct of the locust, Locusta migratoria
    Angela B Lange
    Department of Zoology, University of Toronto, 3359 Mississauga Road, Ont, Canada L5L 1C6
    Peptides 23:2063-70. 2002
  6. ncbi request reprint A neurohormonal role for serotonin in the control of locust oviducts
    Angela B Lange
    Department of Biology, University of Toronto at Mississauga, Mississauga, ON, Canada
    Arch Insect Biochem Physiol 56:179-90. 2004
  7. doi request reprint Effects of the mycotoxin destruxin A on Locusta migratoria visceral muscles
    Esau Ruiz-Sanchez
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, Canada
    Toxicon 56:1043-51. 2010
  8. pmc Identification and expression of the CCAP receptor in the Chagas' disease vector, Rhodnius prolixus, and its involvement in cardiac control
    Dohee Lee
    Department of Biology, University of Toronto Mississauga, Mississauga, Ontario, Canada
    PLoS ONE 8:e68897. 2013
  9. ncbi request reprint Evidence for a possible neurotransmitter/neuromodulator role of tyramine on the locust oviducts
    Andrew Donini
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, Canada, L5L 1C6
    J Insect Physiol 50:351-61. 2004
  10. doi request reprint An unusual myosuppressin from the blood-feeding bug Rhodnius prolixus
    Dohee Lee
    University of Toronto Mississauga, Department of Biology, 3359 Mississauga Road, Mississauga, ON, Canada, L5L 1C6
    J Exp Biol 215:2088-95. 2012

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Evidence for crustacean cardioactive peptide-like innervation of the gut in Locusta migratoria
    Andrew Donini
    Department of Zoology, University of Toronto at Mississauga, 3359, Mississauga Road, North Mississauga, Ont, Canada L5L 1C6
    Peptides 23:1915-23. 2002
    ..Results suggest that a CCAP-like substance acts as a neurotransmitter/neuromodulator at the locust hindgut...
  2. ncbi request reprint Dopaminergic control of foregut contractions in Locusta migratoria
    Angela B Lange
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ont, Canada L5L 1C6
    J Insect Physiol 54:222-30. 2008
    ..Dopamine has direct effects on the foregut muscle in the absence of the ventricular ganglia, inhibiting a proctolin-induced contraction in a dose-dependent manner...
  3. ncbi request reprint The presence and distribution of crustacean cardioactive peptide in the central and peripheral nervous system of the stick insect, Baculum extradentatum
    Angela B Lange
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Rd, Mississauga, ON, Canada L5L 1C6
    Regul Pept 129:191-201. 2005
    ..The presence of CCAP in the central nervous system, the stomatogastric nervous system, the corpus cardiacum and the alimentary canal, suggest broad ranging roles for CCAP in B. extradentatum...
  4. ncbi request reprint Neural and hormonal control of muscular activity of the spermatheca in the locust, Locusta migratoria
    Angela B Lange
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario L5L 1C6, Canada
    Peptides 28:174-84. 2007
    ..A comparison is made between the control of oviducts and spermatheca in L. migratoria with regard to their neural substrate and the composition of neuroactive chemicals...
  5. ncbi request reprint A review of the involvement of proctolin as a cotransmitter and local neurohormone in the oviduct of the locust, Locusta migratoria
    Angela B Lange
    Department of Zoology, University of Toronto, 3359 Mississauga Road, Ont, Canada L5L 1C6
    Peptides 23:2063-70. 2002
    ..1 to 0.2nM. This review extends the role of proctolin in insects, and suggests that proctolin may play a neurohormonal role in the locust...
  6. ncbi request reprint A neurohormonal role for serotonin in the control of locust oviducts
    Angela B Lange
    Department of Biology, University of Toronto at Mississauga, Mississauga, ON, Canada
    Arch Insect Biochem Physiol 56:179-90. 2004
    ....
  7. doi request reprint Effects of the mycotoxin destruxin A on Locusta migratoria visceral muscles
    Esau Ruiz-Sanchez
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, Canada
    Toxicon 56:1043-51. 2010
    ....
  8. pmc Identification and expression of the CCAP receptor in the Chagas' disease vector, Rhodnius prolixus, and its involvement in cardiac control
    Dohee Lee
    Department of Biology, University of Toronto Mississauga, Mississauga, Ontario, Canada
    PLoS ONE 8:e68897. 2013
    ..This is the first report of a GPCR knock-down in R. prolixus and the first report showing that a reduction in CCAPR transcript levels leads to a reduction in cardiac output in any insect. ..
  9. ncbi request reprint Evidence for a possible neurotransmitter/neuromodulator role of tyramine on the locust oviducts
    Andrew Donini
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, Canada, L5L 1C6
    J Insect Physiol 50:351-61. 2004
    ....
  10. doi request reprint An unusual myosuppressin from the blood-feeding bug Rhodnius prolixus
    Dohee Lee
    University of Toronto Mississauga, Department of Biology, 3359 Mississauga Road, Mississauga, ON, Canada, L5L 1C6
    J Exp Biol 215:2088-95. 2012
    ....
  11. doi request reprint Effects of crustacean cardioactive peptide on the hearts of two Orthopteran insects, and the demonstration of a Frank-Starling-like effect
    Sara R da Silva
    Department of Chemistry, University of Toronto Mississauga, Mississauga, Ontario, Canada L5L 1C6
    Gen Comp Endocrinol 171:218-24. 2011
    ..Therefore, crustacean cardioactive peptide alters the contractile properties of cardiac tissue in both B. extradentatum and L. migratoria, allowing for an increase in blood flow and circulation...
  12. ncbi request reprint Proctolin-like immunoreactivity in the central and peripheral nervous systems of the locust, Locusta migratoria
    Lisa Clark
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Rd, Mississauga, Ont, Canada L5L 1C6
    Peptides 27:549-58. 2006
    ..The midgut contained PLI in a regular latticework pattern with many varicosities and blebs. No difference in PLI in cells and processes of the central nervous system (CNS) was found between males and females...
  13. ncbi request reprint The neural and peptidergic control of gut contraction in Locusta migratoria: the effect of an FGLa/AST
    Lisa Robertson
    Department of Biology, University of Toronto Mississauga, Mississauga, Ontario, Canada L5L 1C6
    J Exp Biol 215:3394-402. 2012
    ..Overall, this study shows how FGLa/ASTs contribute to the complex regulation and fine tuning of gut contraction...
  14. doi request reprint Sequencing and biological effects of an adipokinetic/hypertrehalosemic peptide in the stick insect, Baculum extradentatum
    Ayesha Malik
    Department of Biology, University of Toronto Mississauga, Mississauga, ON, Canada
    Peptides 34:51-6. 2012
    ..extradentatum: the tryptophan residue at position 8 is post-translationally modified to kynurenine...
  15. doi request reprint Crustacean cardioactive peptide in the Chagas' disease vector, Rhodnius prolixus: presence, distribution and physiological effects
    Do Hee Lee
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, Canada L5L 1C6
    Gen Comp Endocrinol 174:36-43. 2011
    ..Also, CCAP was found to increase the frequency of the heartbeat in a reversible, dose-dependent manner, with threshold close to 10(-11) M and maximum response at 10(-10) M CCAP...
  16. doi request reprint Neural substrate and allatostatin-like innervation of the gut of Locusta migratoria
    Lisa Robertson
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, Ont, Canada
    J Insect Physiol 56:893-901. 2010
    ....
  17. doi request reprint Tyramine as a possible neurotransmitter/neuromodulator at the spermatheca of the African migratory locust, Locusta migratoria
    Rosa da Silva
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, Ontario L5L 1C6, Canada
    J Insect Physiol 54:1306-13. 2008
    ..Taken together, these results suggest that tyramine may be a co-transmitter with octopamine at the spermatheca, with both neuroactive chemicals acting on an octopamine receptor...
  18. ncbi request reprint The association of serotonin with the alimentary canal of the African migratory locust, Locusta migratoria: distribution, physiology and pharmacological profile
    Goudarz Molaei
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, L5L 1C6, Canada
    J Insect Physiol 49:1073-82. 2003
    ..The serotonin antagonist cyproheptadine was less effective leading to a 39% reduction of the 5x10(-6) M serotonin-induced relaxation. Ketanserin was a weak antagonist...
  19. ncbi request reprint The association of crustacean cardioactive peptide with the spermatheca of the African migratory locust, Locusta migratoria
    Rosa da Silva
    Department of Biology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ont, L5L 1C6 Canada
    J Insect Physiol 52:399-409. 2006
    ..The present study suggests that CCAP acts as a neuromodulator/neurotransmitter at the spermathecal visceral tissue of female Locusta migratoria...
  20. doi request reprint The regulation of cardiac activity by nitric oxide (NO) in the Vietnamese stick insect, Baculum extradentatum
    Rosa da Silva
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, Canada
    Cell Signal 24:1344-50. 2012
    ..Contrary to the cardioexcitatory effect of NO on other insect hearts, we have found that NO inhibits stick insect heart rate independently from any nervous system input, in a similar inhibitory fashion as that of vertebrate hearts...
  21. doi request reprint Effects of the cyclopeptide mycotoxin destruxin A on the Malpighian tubules of Rhodnius prolixus (Stål)
    Esau Ruiz-Sanchez
    Department of Biology, University of Toronto Mississauga, Mississauga, Ontario, Canada
    Toxicon 55:1162-70. 2010
    ..prolixus. Changes in properties of the TEP suggest that one of the target sites for this peptide toxin might be associated with inhibition of the apical V-type H(+) ATPase of tubule cells...
  22. ncbi request reprint Isolation, cloning, and tissue expression of a putative octopamine/tyramine receptor from locust visceral muscle tissues
    Goudarz Molaei
    Department of Biology, University of Toronto at Mississauga, Mississauga, Canada
    Arch Insect Biochem Physiol 59:132-49. 2005
    ..Southern blot analyses using EcoRI and HindIII restriction endonucleases recognized at least two distinct gene bands...
  23. ncbi request reprint The effects of crustacean cardioactive peptide on locust oviducts are calcium-dependent
    Andrew Donini
    Department of Zoology, University of Toronto at Mississauga, 3359, Mississauga Road North, L5L 1C6, Mississauga, Ontario, Canada
    Peptides 23:683-91. 2002
    ..The involvement of calcium from intracellular stores in CCAP-induced contractions of the oviducts is likely since, an intracellular calcium antagonist decreased CCAP-induced contractions by 30-35%...
  24. doi request reprint Neuropeptides modulate the heart of the stick insect Baculum extradentatum
    Angela B Lange
    Department of Biology, University of Toronto Mississauga, Mississauga, Ontario, Canada
    Ann N Y Acad Sci 1163:448-50. 2009
    ..Immunoreactive processes are also localized to the valves of the incurrent ostia and excurrent ostia and to the lateral cardiac nerve and lateral cardiac neurons...
  25. ncbi request reprint Proctolin: A possible releasing factor in the corpus cardiacum/corpus allatum of the locust
    Lisa Clark
    Department of Biology, University of Toronto at Mississauga 3359, Mississauga Rd, Mississauga, Ont, Canada L5L 1C6
    Peptides 27:559-66. 2006
    ..These results suggest that proctolin may act as a releasing factor for AKHs and JH in the locust but does not act as a releasing factor for JH in the cockroach...
  26. pmc The Proctolin Gene and Biological Effects of Proctolin in the Blood-Feeding Bug, Rhodnius prolixus
    Ian Orchard
    Department of Biology, University of Toronto Mississauga Mississauga, ON, Canada
    Front Endocrinol (Lausanne) 2:59. 2011
    ..Contrary to the previous suggestion that proctolin is absent from R. prolixus, proctolin is indeed present and biologically active in this medically important bug...
  27. doi request reprint Tyramine: from octopamine precursor to neuroactive chemical in insects
    Angela B Lange
    Department of Biology, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ont, L5L 1C6 Canada
    Gen Comp Endocrinol 162:18-26. 2009
    ..This composite evidence is strong, although the final proof still awaits analysis on a uniquely identifiable tyraminergic neuron as has been possible with octopamine...
  28. doi request reprint Evidence of a central pattern generator regulating spermathecal muscle activity in Locusta migratoria and its coordination with oviposition
    Rosa da Silva
    Department of Biology, University of Toronto Mississauga, Mississauga, ON, Canada
    J Exp Biol 214:757-63. 2011
    ..These results provide further insight into the intricate coordination and control of reproductive tissues underlying reproductive behaviours in locusts...
  29. ncbi request reprint Evidence for the association of FMRFamide-related peptides with the spermatheca of Locusta migratoria
    Julie Clark
    Department of Zoology, University of Toronto at Mississauga, Ontario, L5L 1C6, Mississauga, Canada
    Peptides 23:613-9. 2002
    ..SchistoFLRFamide, and ADVGHVFLRFamide, had an inhibitory effect, decreasing the amplitude of neurally evoked spermathecal contractions...
  30. ncbi request reprint Neural mechanisms coordinating the female reproductive system in the locust
    Angela B Lange
    Department of Biology, University of Toronto Mississauga, Mississauga, ON, L5L 1C6, Canada
    Front Biosci (Landmark Ed) 14:4401-15. 2009
    ..These neural mechanisms are integrated such as to produce coordinated behavior, leading to the accomplishment of the ultimate task, that of producing viable offspring...
  31. doi request reprint Peptidergic control of the heart of the stick insect, Baculum extradentatum
    Aiza Ejaz
    University of Toronto at Mississauga, Department of Biology, 3359 Mississauga Road, Mississauga, ON L5L 1C6, Canada
    Peptides 29:214-25. 2008
    ..Isolating the dorsal vessel from the ventral nerve cord led to a change in the pattern of heart contractions, from a tonic, stable heart beat, to one which was phasic. The tonic nature was restored by the application of CCAP...
  32. pmc The distribution and physiological effects of the myoinhibiting peptides in the kissing bug, rhodnius prolixus
    Angela B Lange
    Department of Biology, University of Toronto Mississauga Mississauga, ON, Canada
    Front Neurosci 6:98. 2012
    ..In addition, both peptides activate the Drosophila SP receptor. The MIP/SP receptors are therefore activated by peptides with the unusual W(X(7))Wamide motif...