M Labinaz

Summary

Affiliation: University of Ottawa Heart Institute
Country: Canada

Publications

  1. ncbi request reprint Six-month outcomes of percutaneous coronary balloon angioplasty in acute coronary syndromes: Results from the PURSUIT trial
    Marino Labinaz
    University of Ottawa Heart Institute, Ottawa, Ontario
    Can J Cardiol 20:773-8. 2004
  2. ncbi request reprint Outcomes of patients with acute coronary syndromes and prior percutaneous coronary intervention: a pooled analysis of three randomized clinical trials
    Marino Labinaz
    University of Ottawa Heart Institute, Division of Cardiology, 40 Ruskin Ave, Rm H 150 Ottawa, Ontario, K1Y 4W7 Canada
    Eur Heart J 26:128-36. 2005
  3. ncbi request reprint Comparison of one-year outcomes following coronary artery stenting in diabetic versus nondiabetic patients (from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy [ESPRIT] Trial)
    Marino Labinaz
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am J Cardiol 90:585-90. 2002
  4. pmc Meta-analysis of clinical efficacy and bleeding risk with intravenous glycoprotein IIb/IIIa antagonists for percutaneous coronary intervention
    Marino Labinaz
    University of Ottawa Heart Institute, Ottawa, Canada
    Can J Cardiol 23:963-70. 2007
  5. ncbi request reprint Outcomes of patients with acute coronary syndromes and prior coronary artery bypass grafting: results from the platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial
    Marino Labinaz
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Circulation 105:322-7. 2002
  6. pmc Delivery of primary percutaneous coronary intervention for the management of acute ST segment elevation myocardial infarction: summary of the Cardiac Care Network of Ontario Consensus Report
    Marino Labinaz
    University Ottawa Heart Institute, Division of Cardiology, Ottawa, Ontario
    Can J Cardiol 22:243-50. 2006
  7. ncbi request reprint Outcome of acute ST-segment elevation myocardial infarction in patients with prior coronary artery bypass surgery receiving thrombolytic therapy
    M Labinaz
    University of Ottawa Heart Institute, Department of Medicine, Division of Cardiology, Room 150, 40 Ruskin Ave, Ottawa, Ontario K1Y 4W7, Canada
    Am Heart J 141:469-77. 2001
  8. ncbi request reprint Infusion of an antialpha4 integrin antibody is associated with less neoadventitial formation after balloon injury of porcine coronary arteries
    M Labinaz
    University of Ottawa Heart Institute, Ottawa, Canada
    Can J Cardiol 16:187-96. 2000
  9. ncbi request reprint A comparison of clinical outcomes between Canadian and American patients after nonurgent coronary stenting
    Mina Madan
    Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Can J Cardiol 20:1343-9. 2004
  10. ncbi request reprint Establishing an approach for patients with recent coronary occlusion: identification of viable myocardium
    R S Beanlands
    Division of Cardiology, University of Ottawa Heart Institute, Ontario, Canada
    J Nucl Cardiol 6:298-305. 1999

Detail Information

Publications41

  1. ncbi request reprint Six-month outcomes of percutaneous coronary balloon angioplasty in acute coronary syndromes: Results from the PURSUIT trial
    Marino Labinaz
    University of Ottawa Heart Institute, Ottawa, Ontario
    Can J Cardiol 20:773-8. 2004
    ..For patients with ACS undergoing percutaneous balloon angioplasty without coronary stenting in the era of platelet glycoprotein IIb/IIIa blockade, the long-term prognosis is less clear...
  2. ncbi request reprint Outcomes of patients with acute coronary syndromes and prior percutaneous coronary intervention: a pooled analysis of three randomized clinical trials
    Marino Labinaz
    University of Ottawa Heart Institute, Division of Cardiology, 40 Ruskin Ave, Rm H 150 Ottawa, Ontario, K1Y 4W7 Canada
    Eur Heart J 26:128-36. 2005
    ..We sought to characterize the outcomes of patients with a prior percutaneous coronary intervention (PCI) who presented with a non-ST-segment elevation acute coronary syndrome (ACS)...
  3. ncbi request reprint Comparison of one-year outcomes following coronary artery stenting in diabetic versus nondiabetic patients (from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy [ESPRIT] Trial)
    Marino Labinaz
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am J Cardiol 90:585-90. 2002
    ..There is no evidence of a statistical interaction in the treatment effect of eptifibatide between patients with and without diabetes...
  4. pmc Meta-analysis of clinical efficacy and bleeding risk with intravenous glycoprotein IIb/IIIa antagonists for percutaneous coronary intervention
    Marino Labinaz
    University of Ottawa Heart Institute, Ottawa, Canada
    Can J Cardiol 23:963-70. 2007
    ..The purpose of the present study was to provide an up-to-date meta-analysis on the clinical efficacy and safety of intravenous GP IIb/IIIa antagonists in patients undergoing PCI...
  5. ncbi request reprint Outcomes of patients with acute coronary syndromes and prior coronary artery bypass grafting: results from the platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial
    Marino Labinaz
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Circulation 105:322-7. 2002
    ..90 [95% CI, 0.67 to 1.20]) and in patients without a history of CABG (unadjusted HR, 0.89 [95% CI, 0.80 to 0.99])...
  6. pmc Delivery of primary percutaneous coronary intervention for the management of acute ST segment elevation myocardial infarction: summary of the Cardiac Care Network of Ontario Consensus Report
    Marino Labinaz
    University Ottawa Heart Institute, Division of Cardiology, Ottawa, Ontario
    Can J Cardiol 22:243-50. 2006
    ....
  7. ncbi request reprint Outcome of acute ST-segment elevation myocardial infarction in patients with prior coronary artery bypass surgery receiving thrombolytic therapy
    M Labinaz
    University of Ottawa Heart Institute, Department of Medicine, Division of Cardiology, Room 150, 40 Ruskin Ave, Ottawa, Ontario K1Y 4W7, Canada
    Am Heart J 141:469-77. 2001
    ..We assessed the characteristics and outcomes of such patients undergoing thrombolysis for acute MI...
  8. ncbi request reprint Infusion of an antialpha4 integrin antibody is associated with less neoadventitial formation after balloon injury of porcine coronary arteries
    M Labinaz
    University of Ottawa Heart Institute, Ottawa, Canada
    Can J Cardiol 16:187-96. 2000
    ..The adventitial response to balloon injury is an important determinant of neointimal formation and arterial remodelling...
  9. ncbi request reprint A comparison of clinical outcomes between Canadian and American patients after nonurgent coronary stenting
    Mina Madan
    Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Can J Cardiol 20:1343-9. 2004
    ..Few data are available comparing PCI outcomes between the two countries in the era of coronary stenting and adjunctive glycoprotein IIb/IIIa inhibition...
  10. ncbi request reprint Establishing an approach for patients with recent coronary occlusion: identification of viable myocardium
    R S Beanlands
    Division of Cardiology, University of Ottawa Heart Institute, Ontario, Canada
    J Nucl Cardiol 6:298-305. 1999
    ....
  11. ncbi request reprint Stenting versus thrombolysis in acute myocardial infarction trial (STAT)
    M R Le May
    Division of Cardiology, University of Ottawa Heart Institute, Canada
    J Am Coll Cardiol 37:985-91. 2001
    ..We sought to directly compare primary stenting with accelerated tissue plasminogen activator (t-PA) in patients presenting with acute ST-elevation myocardial infarction (AMI)...
  12. ncbi request reprint Time course and importance of neoadventitial formation in arterial remodeling following balloon angioplasty of porcine coronary arteries
    M Labinaz
    Department of Medicine, University of Ottawa Heart Institute, Ontario, Canada
    Cardiovasc Res 41:255-66. 1999
    ..We hypothesized that arterial remodeling does not occur in all arteries following balloon injury and is dependent on neoadventitial formation...
  13. ncbi request reprint Current reperfusion strategies for ST elevation myocardial infarction: a Canadian perspective
    Catherine S McLellan
    University of Ottawa Heart Institute, Ottawa, Canada
    Can J Cardiol 20:525-33. 2004
    ..The literature regarding pharmacological and mechanical reperfusion is reviewed to emphasize the important issues while a future strategy of facilitated PCI is contemplated...
  14. ncbi request reprint Risk scores for risk stratification in acute coronary syndromes: useful but simpler is not necessarily better
    Andrew T Yan
    Canadian Heart Research Centre, Toronto, Ontario, Canada
    Eur Heart J 28:1072-8. 2007
    ....
  15. ncbi request reprint Safety of coronary stenting with eptifibatide and ultra-low-dose heparin
    Michel Le May
    The University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am J Cardiol 95:630-2. 2005
    ..At 30 days, all patients were free of the primary clinical outcomes defined as a composite of death, myocardial infarction, or repeat target vessel revascularization, and there were no major bleeding complications...
  16. ncbi request reprint Comparison of early mortality of paramedic-diagnosed ST-segment elevation myocardial infarction with immediate transport to a designated primary percutaneous coronary intervention center to that of similar patients transported to the nearest hospital
    Michel R Le May
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am J Cardiol 98:1329-33. 2006
    ..In conclusion, paramedic-referred primary PCI is a safe and feasible strategy for treating STEMI that is associated with rapid and effective reperfusion and very low in-hospital mortality...
  17. ncbi request reprint Hospitalization costs of primary stenting versus thrombolysis in acute myocardial infarction: cost analysis of the Canadian STAT Study
    Michel R Le May
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    Circulation 108:2624-30. 2003
    ..This study looks at the hospitalization costs of primary stenting compared with accelerated tPA...
  18. ncbi request reprint A citywide protocol for primary PCI in ST-segment elevation myocardial infarction
    Michel R Le May
    University of Ottawa Heart Institute, Ottawa, ON, Canada
    N Engl J Med 358:231-40. 2008
    ..The benchmark for a timely PCI intervention has become a door-to-balloon time of less than 90 minutes. Whether regional strategies can be developed to achieve this goal is uncertain...
  19. ncbi request reprint Association of aspirin dosage to clinical outcomes after percutaneous coronary intervention: observations from the Ottawa Heart Institute PCI Registry
    Derek So
    University of Ottawa Heart Institute, Cardiology, Ottawa, Ontario, Canada
    J Invasive Cardiol 21:121-7. 2009
    ..The purpose of this study was to test the hypothesis that high-dose aspirin of 325 mg decreases death and myocardial infarction (MI) compared to a lower dose of 81 mg in patients undergoing PCI...
  20. doi request reprint Primary percutaneous coronary angioplasty with and without eptifibatide in ST-segment elevation myocardial infarction: a safety and efficacy study of integrilin-facilitated versus primary percutaneous coronary intervention in ST-segment elevation myocardi
    Michel R Le May
    University of Ottawa Heart Institute, Division of Cardiology, Ottawa, Ontario, Canada
    Circ Cardiovasc Interv 2:330-8. 2009
    ..We sought to determine whether eptifibatide, a platelet glycoprotein IIb/IIIa inhibitor, given before catheterization would improve clinical outcomes in patients referred for primary percutaneous coronary intervention...
  21. doi request reprint Transcatheter aortic-valve replacement: a cardiac surgeon and cardiologist team perspective
    Marc Ruel
    Division of Cardiac Surgery, University of Ottawa, Ontario, Canada
    Curr Opin Cardiol 25:107-13. 2010
    ..Transcatheter aortic-valve implantation is a promising new treatment modality for patients with aortic-valve disease, where it may revolutionize the treatment of elderly and high-risk patients...
  22. doi request reprint Interventional valve surgery: building a team and working together
    Marc Ruel
    Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Semin Thorac Cardiovasc Surg 22:145-9. 2010
    ....
  23. ncbi request reprint Combined angioplasty and pharmacological intervention versus thrombolysis alone in acute myocardial infarction (CAPITAL AMI study)
    Michel R Le May
    Division of Cardiology, University of Ottawa, Ottawa, Ontario, Canada
    J Am Coll Cardiol 46:417-24. 2005
    ..We compared a strategy of tenecteplase (TNK)-facilitated angioplasty with one of TNK alone in patients presenting with high-risk ST-segment elevation myocardial infarction (STEMI)...
  24. ncbi request reprint Predictors of improvement in left ventricular function after percutaneous revascularization of occluded coronary arteries: a report from the Total Occlusion Study of Canada (TOSCA)
    V Dzavik
    University Health Network, Toronto, Ontario, Canada
    Am Heart J 142:301-8. 2001
    ....
  25. ncbi request reprint Which heparin and how much?
    Peter E Ruchin
    Cardiac Catheterization Laboratory, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    Curr Cardiol Rep 10:312-8. 2008
    ..Finally, there is concern over unwanted thrombotic events with these agents in the cardiac catheterization laboratory...
  26. ncbi request reprint Gene dosage of the common variant 9p21 predicts severity of coronary artery disease
    Sonny Dandona
    John and Jennifer Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada
    J Am Coll Cardiol 56:479-86. 2010
    ..The purpose of this study was to test the hypothesis that 9p21 gene dosage determines the severity of coronary artery disease (CAD)...
  27. ncbi request reprint Lesion characteristics and coronary stent selection with computed tomographic coronary angiography: a pilot investigation comparing CTA, QCA and IVUS
    Malek Kass
    Department of Medicine Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    J Invasive Cardiol 22:328-34. 2010
    ..Computed tomographic coronary angiography (CTA) has been shown to correlate well with QCA and IVUS in the assessment of coronary stenoses and may also have a role in stent guidance...
  28. doi request reprint Safety and effectiveness of drug-eluting and bare-metal stents for patients with off- and on-label indications
    Dennis T Ko
    Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Am Coll Cardiol 53:1773-82. 2009
    ..Our main objective was to evaluate the longer-term safety and efficacy of drug-eluting stents (DES) in off-label indications as compared with bare-metal stents (BMS)...
  29. ncbi request reprint Human in-stent restenosis tissue obtained by means of coronary atherectomy consists of an abundant proteoglycan matrix with a paucity of cell proliferation
    Chris Glover
    Vascular Biology Laboratory, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am Heart J 144:702-9. 2002
    ..The purpose of this study was to examine the histologic features and proliferation profile of coronary ISR tissue derived from atherectomy procedures performed on patients with clinical evidence of ISR...
  30. pmc Effect of operator and institutional volume on clinical outcomes after percutaneous coronary interventions performed in Canada and the United States: a brief report from the Enhanced Suppression of the Platelet glycoprotein IIb/IIIa Receptor with Integril
    Mina Madan
    Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Can J Cardiol 25:e269-72. 2009
    ..It was previously reported that Canadian patients had reduced rates of 30-day and one-year death, myocardial infarction (MI) or target vessel revascularization (TVR) compared with patients in the United States (US)...
  31. ncbi request reprint Potential utility of rubidium 82 PET quantification in patients with 3-vessel coronary artery disease
    R Parkash
    Cardiac PET Center, Department of Medicine, University of Ottawa Heart Institute, Ontario, Canada
    J Nucl Cardiol 11:440-9. 2004
    ..This study determined whether positron emission tomography quantification of perfusion reserve by use of rubidium 82 net retention defined a greater extent of disease than the standard approach in patients with 3-vessel disease...
  32. ncbi request reprint Acute outcome with the flexicut directional coronary atherectomy catheter for the treatment of coronary in-stent restenosis
    E R O'Brien
    Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Invasive Cardiol 13:618-22. 2001
    ..Long-term follow-up of these and additional patients will be helpful in determining the efficacy of the Flexicut atherectomy catheter for the treatment of ISR...
  33. ncbi request reprint Thrombus of the ascending aorta: a rare cause of myocardial infarction
    Allan L Wolfsohn
    Division of Anatomical Pathology, Ottawa Hospital, Ottawa, ON, Canada, K1Y 4E9
    Cardiovasc Pathol 14:214-8. 2005
    ..The diagnosis may be obtained by transesophageal echocardiography, and we generally recommend surgical thrombectomy...
  34. ncbi request reprint Association between completeness of percutaneous coronary revascularization and postprocedure outcomes
    Catherine S McLellan
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am Heart J 150:800-6. 2005
    ..This study evaluated multivessel PCI patients to determine the predictors of complete revascularization and the association of complete revascularization with survival, subsequent CABG, and repeat PCI...
  35. ncbi request reprint Using personal digital assistants and patient care algorithms to improve access to cardiac care best practices
    Kathryn L Momtahan
    The Ottawa Hospital, Nursing Professional Practice Department, Ottawa, Ontario, Canada
    Stud Health Technol Inform 129:117-21. 2007
    ....
  36. pmc The Canadian Association of Interventional Cardiology and the Canadian Cardiovascular Society joint statement on drug-eluting stents
    Machael P Love
    Division of Cardiology, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia
    Can J Cardiol 23:121-3. 2007
    ..The purpose of the present statement is to summarize the available evidence relating to DES thrombosis and to provide practical recommendations regarding DES use and antiplatelet therapy...
  37. ncbi request reprint Cardiac Angiography in Renally Impaired Patients (CARE) study: a randomized double-blind trial of contrast-induced nephropathy in patients with chronic kidney disease
    Richard J Solomon
    Department of Renal Services, Fletcher Allen Health Care, University of Vermont, Burlington, VT 05401, USA
    Circulation 115:3189-96. 2007
    ..No direct comparisons exist of the renal tolerability of the low-osmolality contrast medium iopamidol with that of the iso-osmolality contrast medium iodixanol in high-risk patients...
  38. ncbi request reprint Long-term efficacy of platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention
    J Conor O'Shea
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27705
    JAMA 287:618-21. 2002
    ....
  39. ncbi request reprint Reduction of myocardial ischemic injury following coronary intervention (the MC-1 to Eliminate Necrosis and Damage trial)
    David E Kandzari
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am J Cardiol 92:660-4. 2003
    ..These results support the evaluation of MC-1 in pivotal trials of patients at risk for developing myocardial ischemia, infarction, or reperfusion injury...
  40. ncbi request reprint Randomized, blinded trial comparing fondaparinux with unfractionated heparin in patients undergoing contemporary percutaneous coronary intervention: Arixtra Study in Percutaneous Coronary Intervention: a Randomized Evaluation (ASPIRE) Pilot Trial
    Shamir R Mehta
    McMaster University and the Population Health Research Institute, Hamilton Health Sciences, General Division, 237 Barton St E, Hamilton, Ontario, Canada L6K 1B8
    Circulation 111:1390-7. 2005
    ..We performed a randomized trial to determine the safety and feasibility of fondaparinux in the percutaneous coronary intervention (PCI) setting...
  41. ncbi request reprint Noncardiac surgery in patients with coronary artery stent: what should the anesthesiologist know?
    Jean Yves Dupuis
    Can J Anaesth 52:356-61. 2005