D Krewski

Summary

Affiliation: University of Ottawa
Country: Canada

Publications

  1. ncbi request reprint Reanalysis of the Harvard Six Cities Study, part II: sensitivity analysis
    D Krewski
    McLaughlin Centre for Population Health Risk Assessment, Institute for Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Inhal Toxicol 17:343-53. 2005
  2. pmc INTEROCC case-control study: lack of association between glioma tumors and occupational exposure to selected combustion products, dusts and other chemical agents
    Aude Lacourt
    University of Montreal Hospital Research Centre CRCHUM, Montreal, Canada
    BMC Public Health 13:340. 2013
  3. pmc Development of a wearable global positioning system for place and health research
    Daniel Rainham
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Int J Health Geogr 7:59. 2008
  4. doi request reprint Development of a copper database for exposure-response analysis
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada
    J Toxicol Environ Health A 73:208-16. 2010
  5. ncbi request reprint Reanalysis of the Harvard Six Cities Study, part I: validation and replication
    D Krewski
    McLaughlin Centre for Population Health Risk Assessment, Institute for Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Inhal Toxicol 17:335-42. 2005
  6. doi request reprint Toxicity testing in the 21st century: a vision and a strategy
    Daniel Krewski
    R Samuel McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health B Crit Rev 13:51-138. 2010
  7. ncbi request reprint Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studies
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Epidemiology 16:137-45. 2005
  8. ncbi request reprint Managing the microbiological risks of drinking water
    Daniel Krewski
    McLaughlin Centre for Population Health, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 67:1591-617. 2004
  9. ncbi request reprint Managing health risks from drinking water--a report to the Walkerton inquiry
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 65:1635-823. 2002
  10. ncbi request reprint Development of acute exposure guideline levels for airborne exposures to hazardous substances
    Daniel Krewski
    University of Ottawa, Ottawa, Ont, Canada
    Regul Toxicol Pharmacol 39:184-201. 2004

Collaborators

Detail Information

Publications125 found, 100 shown here

  1. ncbi request reprint Reanalysis of the Harvard Six Cities Study, part II: sensitivity analysis
    D Krewski
    McLaughlin Centre for Population Health Risk Assessment, Institute for Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Inhal Toxicol 17:343-53. 2005
    ..Overall, this extensive sensitivity analysis both supported the conclusions reached by the original investigators and demonstrated the robustness of these conclusions to alternative analytic approaches...
  2. pmc INTEROCC case-control study: lack of association between glioma tumors and occupational exposure to selected combustion products, dusts and other chemical agents
    Aude Lacourt
    University of Montreal Hospital Research Centre CRCHUM, Montreal, Canada
    BMC Public Health 13:340. 2013
    ....
  3. pmc Development of a wearable global positioning system for place and health research
    Daniel Rainham
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Int J Health Geogr 7:59. 2008
    ..Person-specific GPS data provides a useful source of information to operationalize the concept of place...
  4. doi request reprint Development of a copper database for exposure-response analysis
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada
    J Toxicol Environ Health A 73:208-16. 2010
    ..Efforts are underway to use this database to define the exposure-response curve for Cu excess and deficiency; however, the comprehensive database can be used to carry out other in-depth analyses on Cu toxicity...
  5. ncbi request reprint Reanalysis of the Harvard Six Cities Study, part I: validation and replication
    D Krewski
    McLaughlin Centre for Population Health Risk Assessment, Institute for Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Inhal Toxicol 17:335-42. 2005
    ....
  6. doi request reprint Toxicity testing in the 21st century: a vision and a strategy
    Daniel Krewski
    R Samuel McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health B Crit Rev 13:51-138. 2010
    ..Implementation of these strategies would result in a new toxicity testing paradigm firmly based on human biology...
  7. ncbi request reprint Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studies
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Epidemiology 16:137-45. 2005
    ..Residential exposure to radon is at much lower levels, and the risk of lung cancer with residential exposure is less clear. We conducted a systematic analysis of pooled data from all North American residential radon studies...
  8. ncbi request reprint Managing the microbiological risks of drinking water
    Daniel Krewski
    McLaughlin Centre for Population Health, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 67:1591-617. 2004
    ....
  9. ncbi request reprint Managing health risks from drinking water--a report to the Walkerton inquiry
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 65:1635-823. 2002
  10. ncbi request reprint Development of acute exposure guideline levels for airborne exposures to hazardous substances
    Daniel Krewski
    University of Ottawa, Ottawa, Ont, Canada
    Regul Toxicol Pharmacol 39:184-201. 2004
    ..Techniques are discussed for the extrapolation of effects across different exposure durations. AEGLs provide a viable approach for assisting in the prevention, planning, and response to acute airborne exposures to toxic agents...
  11. ncbi request reprint Overview of the reanalysis of the Harvard Six Cities Study and American Cancer Society Study of Particulate Air Pollution and Mortality
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 66:1507-51. 2003
    ..Collectively, our reanalysis suggest that mortality may be attributable to more than one component of the complex mixture of ambient air pollutants for U.S. urban areas...
  12. doi request reprint The use of categorical regression in modeling copper exposure-response relationships
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario K1N N5, Canada
    J Toxicol Environ Health A 73:187-207. 2010
    ..The resulting exposure-response model could be used to provide information in the determination of an acceptable range of oral intake for Cu...
  13. ncbi request reprint A combined analysis of North American case-control studies of residential radon and lung cancer
    Daniel Krewski
    Department of Epidemiology and Community Medicine, Faculty of Medicine, McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 69:533-97. 2006
    ..Collectively, these results provide direct evidence of an association between residential radon and lung cancer risk, a finding predicted by extrapolation of results from occupational studies of radon-exposed underground miners...
  14. ncbi request reprint Recent advances in research on radiofrequency fields and health: 2001-2003
    Daniel Krewski
    R Samuel McLaughlin Center for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health B Crit Rev 10:287-318. 2007
    ..The results of the ongoing World Health Organization (WHO) study of mobile phones will provide important new information in this regard...
  15. doi request reprint New directions in toxicity testing
    Daniel Krewski
    McLaughlin Center for Population Health Risk Assessment, University of Ottawa, Ontario, Canada
    Annu Rev Public Health 32:161-78. 2011
    ..The implications of the NRC vision for toxicity testing for regulatory risk assessment are also discussed...
  16. ncbi request reprint Ambient air pollution and population health: overview
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 70:275-83. 2007
    ..However, there remains the challenge of how best to achieve these reductions...
  17. ncbi request reprint Association between ozone and hospitalization for respiratory diseases in 16 Canadian cities
    R T Burnett
    Health Canada, Environmental Health Center, Tunney s Pasture, Ottawa, Ontario, Canada
    Environ Res 72:24-31. 1997
    ....
  18. ncbi request reprint Adjusting for temporal variation in the analysis of parallel time series of health and environmental variables
    S Cakmak
    Health Protection Branch, Health Canada, Ottawa, Ontario, Canada
    J Expo Anal Environ Epidemiol 8:129-44. 1998
    ..The association between ambient ozone levels and hospital admissions for respiratory diseases was also sensitive to the season of examination, with weaker associations observed outside the summer months...
  19. ncbi request reprint Spatial analysis of the air pollution-mortality relationship in the context of ecologic confounders
    Michael Jerrett
    School of Geography and Geology, McMaster University, Hamilton, Ontario, Canada
    J Toxicol Environ Health A 66:1735-77. 2003
    ..Confidence limits for the sulfate relative risk include unity in models that simultaneously control for sulfur dioxide and autocorrelation...
  20. pmc Effect of short-term exposure to gaseous pollution on asthma hospitalisation in children: a bi-directional case-crossover analysis
    M Lin
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada
    J Epidemiol Community Health 57:50-5. 2003
    ..Assess associations between short-term exposure to gaseous pollutants and asthma hospitalisation among boys and girls 6 to12 years of age...
  21. ncbi request reprint Association between particulate- and gas-phase components of urban air pollution and daily mortality in eight Canadian cities
    R T Burnett
    Environmental Health Directorate, Health Canada, Ottawa, and Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada
    Inhal Toxicol 12:15-39. 2000
    ..We recommend that measurements of elemental and organic carbon be undertaken in Canadian urban environments to examine their potential effects on human health...
  22. pmc The influence of ambient coarse particulate matter on asthma hospitalization in children: case-crossover and time-series analyses
    Mei Lin
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Canada
    Environ Health Perspect 110:575-81. 2002
    ..For the most part, relative risk estimates from the unidirectional case-crossover analysis were more pronounced compared with both bidirectional case-crossover and time-series analyses...
  23. ncbi request reprint Association between air pollution and multiple respiratory hospitalizations among the elderly in Vancouver, Canada
    Karen Y Fung
    Department of Mathematics and Statistics, University of Windsor, Windsor, Ontario, Canada
    Inhal Toxicol 18:1005-11. 2006
    ..018-1.070). We also found PM10-2.5 for 3-day and 5-day lag to be significant, with the strongest association at 5-day lag (RR = 1.020, 95% CI: 1.001-1.039). No significant associations with admission were found with current day exposure...
  24. ncbi request reprint Assessment and management of residential radon health risks: a report from the health Canada radon workshop
    Bliss L Tracy
    Radiation Protection Bureau, Health Canada, Ottawa, Ontario
    J Toxicol Environ Health A 69:735-58. 2006
    ..The various elements of a comprehensive national radon policy were set forth...
  25. ncbi request reprint First analysis of cancer incidence and occupational radiation exposure based on the National Dose Registry of Canada
    W N Sont
    Radiation Protection Bureau, Health Canada, Ottawa, Ontario
    Am J Epidemiol 153:309-18. 2001
    ..The thyroid standardized incidence ratios in this study are highly significant, but further investigation is needed to assess the possibility of association with occupational radiation exposure...
  26. pmc On the relationship between time-series studies, dynamic population studies, and estimating loss of life due to short-term exposure to environmental risks
    Richard T Burnett
    Biostatistics and Epidemiology Division, Safe Environments Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada
    Environ Health Perspect 111:1170-4. 2003
    ..Issues in extrapolating risk estimates based on time-series studies in one population to estimate the amount of life lost in another population are also discussed...
  27. doi request reprint Low dose ionizing radiation exposure and cardiovascular disease mortality: cohort study based on Canadian national dose registry of radiation workers
    Jan M Zielinski
    Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada
    Int J Occup Med Environ Health 22:27-33. 2009
    ....
  28. ncbi request reprint The effect of censoring on cancer risk estimates based on the Canadian National Dose Registry of occupational radiation exposure
    Hwashin Shin
    R Samuel McLaughlin Centre for Population Health Risk Assessment, Ottawa, ON, Canada
    J Expo Anal Environ Epidemiol 15:398-406. 2005
    ....
  29. ncbi request reprint Mortality and long-term exposure to ambient air pollution: ongoing analyses based on the American Cancer Society cohort
    Daniel Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 68:1093-109. 2005
    ..Information on the influence of covariates at multiple scales and of critical exposure time windows can assist policymakers in establishing timelines for regulatory interventions that maximize population health benefits...
  30. ncbi request reprint Impact of particulate air pollution on quality-adjusted life expectancy in Canada
    Douglas Coyle
    Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 66:1847-63. 2003
    ..Further analysis can assess the efficiency of targeting such initiatives to communities that are most likely to benefit...
  31. ncbi request reprint Asthma and the risk of hospitalization in Canada : the role of socioeconomic and demographic factors
    Y Chen
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Chest 119:708-13. 2001
    ..Asthma is an important determinant of hospitalization. The study aims to examine the modifying effects of demographic and socioeconomic factors on the relationship between asthma and the overall number of hospitalizations...
  32. pmc The spatial association between community air pollution and mortality: a new method of analyzing correlated geographic cohort data
    R Burnett
    Healthy Environments and Consumer Safety Branch, Health Canada, 200 Environmental Health Centre, Tunney s Pasture, Ottawa, Ontario, Canada K1A 0L2
    Environ Health Perspect 109:375-80. 2001
    ..Failure to account for extravariation and spatial autocorrelation can lead to an understatement of the uncertainty of the air pollution association with mortality...
  33. doi request reprint Survey of public perceptions of prion disease risks in Canada: what does the public care about?
    L Lemyre
    GAP Santé Research Unit, McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 72:1113-21. 2009
    ....
  34. ncbi request reprint Association between ozone and hospitalization for acute respiratory diseases in children less than 2 years of age
    R T Burnett
    Environmental Health Directorate, Health Canada, 200 Environmental Health Center, Tunney s Pasture, Ottawa, Ontario, Canada K1A OL2
    Am J Epidemiol 153:444-52. 2001
    ..Ozone was not associated with hospital admissions during the September-April period. Ambient ozone levels in the summertime should be considered a risk factor for respiratory problems in children less than 2 years of age...
  35. doi request reprint Health outcomes of low-dose ionizing radiation exposure among medical workers: a cohort study of the Canadian national dose registry of radiation workers
    Jan M Zielinski
    Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada
    Int J Occup Med Environ Health 22:149-56. 2009
    ..Since such extrapolations are subject to uncertainty, direct information is needed on the risk associated with chronic low-dose occupational exposure to ionizing radiation...
  36. doi request reprint Canadian National Dose Registry of radiation workers: overview of research from 1951 through 2007
    Jan M Zielinski
    Health Environments and Consumer Safety Branch, Health Canada, Tunney s Pasture, Ottawa, Ontario, Canada
    Int J Occup Med Environ Health 21:269-75. 2008
    ..Evidence of an inverse dose-rate effect (i.e. an increase in the risk with a protraction of a given cumulative dose) was found in the NDR cohort...
  37. ncbi request reprint Association between ozone and respiratory admissions among children and the elderly in Vancouver, Canada
    Qiuying Yang
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Inhal Toxicol 15:1297-308. 2003
    ..These associations persisted after adjustment for both copollutant exposures and socioeconomic status...
  38. ncbi request reprint The use of biologically based cancer risk models in radiation epidemiology
    D Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, One Stewart Street, Room 320, Ottawa, Ontario, Canada K1N 6N5
    Radiat Prot Dosimetry 104:367-76. 2003
    ....
  39. ncbi request reprint Spatial regression models for large-cohort studies linking community air pollution and health
    Sabit Cakmak
    Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 66:1811-23. 2003
    ..From a statistical point of view, it appears that a location surface in the deterministic component of the model was preferred to a distance-decay autocorrelation structure in the model's stochastic component...
  40. ncbi request reprint Gaseous air pollutants and asthma hospitalization of children with low household income in Vancouver, British Columbia, Canada
    Mei Lin
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Am J Epidemiol 159:294-303. 2004
    ..No significantly positive associations were found between carbon monoxide and ozone and asthma hospitalization in either low or high socioeconomic groups...
  41. pmc Chlorination disinfection by-products and pancreatic cancer risk
    Minh T Do
    Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Environ Health Perspect 113:418-24. 2005
    ..3). Null findings were also obtained assuming a latency period for pancreatic cancer induction of 3, 8, or 13 years...
  42. ncbi request reprint Air quality risk assessment and management
    Yue Chen
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 71:24-39. 2008
    ..These initiatives serve as the legislative framework for air quality management in North America and Europe...
  43. ncbi request reprint Health risks of electromagnetic fields. Part III: Risk analysis
    Lynn M Brodsky
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Crit Rev Biomed Eng 31:333-54. 2003
    ..Thus it is essential that all stakeholders involved in this issue participate in developing consensus solutions...
  44. ncbi request reprint Neonatal mortality and morbidity in vertex-vertex second twins according to mode of delivery and birth weight
    Q Yang
    OMNI Research Group, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, and Ottawa Health Research Institute, Ottawa, Canada
    J Perinatol 26:3-10. 2006
    ..To assess the risk of neonatal mortality and morbidity in vertex-vertex second twins according to mode of delivery and birth weight...
  45. ncbi request reprint Testing the harvesting hypothesis by time-domain regression analysis. II: covariate effects
    Karen Fung
    Department of Mathematics and Statistics, University of Windsor, Windsor, Ontario, Canada
    J Toxicol Environ Health A 68:1155-65. 2005
    ..We believe that time-scale regression has limited value for detecting mortality displacement in time-series data...
  46. ncbi request reprint Association between particulate air pollution and first hospital admission for childhood respiratory illness in Vancouver, Canada
    Qiuying Yang
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Arch Environ Health 59:14-21. 2004
    ..22 (1.02, 1.48) and 1.14 (0.99, 1.32). The data indicated the possibility of harmful effects from coarse PM on first hospitalization for respiratory disease in early childhood...
  47. ncbi request reprint In utero pesticide exposure and childhood morbidity
    Mandy Weselak
    R Samuel McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Canada
    Environ Res 103:79-86. 2007
    ....
  48. ncbi request reprint World Health Organization's International Radon Project
    Jan M Zielinski
    Healthy Environments and Consumer Safety Branch, Safe Environments Program, Health Canada, Ottawa, Ontario
    J Toxicol Environ Health A 69:759-69. 2006
    ....
  49. ncbi request reprint Adolescent injuries in Canada: findings from the Canadian community health survey, 2000-2001
    Frank Mo
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, ON KIN 6N5, Canada
    Int J Inj Contr Saf Promot 13:235-44. 2006
    ..Low socio-economic status was inversely associated with the occurrence of injury in the past year whereas risk-taking behaviour in the form of cigarette smoking and drinking alcohol was positively associated with injury occurrence...
  50. ncbi request reprint Testing the harvesting hypothesis by time-domain regression analysis. I: baseline analysis
    Karen Fung
    Department of Mathematics and Statistics, University of Windsor, Windsor, Ontario, Canada
    J Toxicol Environ Health A 68:1137-54. 2005
    ..If pollution affects mortality in the frail pool more than entrants, larger effects will occur at shorter time scales...
  51. doi request reprint Health risk perceptions as mediators of socioeconomic differentials in health behaviour
    Jennifer E C Lee
    Institute of Population Health, University of Ottawa, ON, Canada
    J Health Psychol 13:1082-91. 2008
    ..Findings underscore the importance of improving the social environment to fostering better lifestyle and health among disadvantaged individuals...
  52. ncbi request reprint Fine particulate air pollution and all-cause mortality within the Harvard Six-Cities Study: variations in risk by period of exposure
    Paul J Villeneuve
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Ann Epidemiol 12:568-76. 2002
    ..We used Poisson regression methods to examine the relation between temporal changes in the levels of fine particulate air pollution (PM(2.5)) and the risk of mortality among participants of the Harvard Six Cities longitudinal study...
  53. ncbi request reprint Leisure-time energy expenditure in asthmatics and non-asthmatics
    Y Chen
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ontario, Canada
    Respir Med 95:13-8. 2001
    ..It was concluded that asthmatics were not consistently inactive compared with non-asthmatics. Leisure-time physical activity cannot explain the positive association between obesity and asthma...
  54. ncbi request reprint Strategies for clean air and health
    L Craig
    Institute for Risk Research, University of Waterloo, Waterloo, Ontario, Canada
    J Toxicol Environ Health A 70:187-90. 2007
    ....
  55. ncbi request reprint Gender-related differences in the association between socioeconomic status and self-reported diabetes
    Mei Tang
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Int J Epidemiol 32:381-5. 2003
    ..The prevalence of diabetes has been steadily increasing in Western countries. We investigated the impact of socioeconomic status (SES) on the prevalence of self-reported diabetes, and its differences between genders...
  56. pmc A systematic review and meta-analysis of childhood leukemia and parental occupational pesticide exposure
    Donald T Wigle
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Environ Health Perspect 117:1505-13. 2009
    ..We conducted a systematic review and meta-analysis of childhood leukemia and parental occupational pesticide exposure...
  57. ncbi request reprint Selection of ecologic covariates in the American Cancer Society study
    Alette Willis
    Department of Geography and Environmental Studies, Carleton University, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 66:1563-89. 2003
    ....
  58. doi request reprint Multi-jurisdictional expert opinion for improving children's environmental health protection
    Michael G Tyshenko
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Int J Environ Health Res 19:81-96. 2009
    ..Three main areas suggested for strengthening children's environmental health protection included: research and surveillance, institutional organization, and regulatory capacity...
  59. doi request reprint Assessing and managing risks arising from exposure to endocrine-active chemicals
    Karen P Phillips
    Faculty of Health Sciences, University of Ottawa, Ontario, Canada
    J Toxicol Environ Health B Crit Rev 11:351-72. 2008
    ....
  60. doi request reprint Risk assessment practice for essential metals
    M E Meek
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada
    J Toxicol Environ Health A 73:253-60. 2010
    ..Subsequently, recommendations for pragmatic next steps to advance progress and facilitate uptake by the regulatory risk assessment community are presented...
  61. ncbi request reprint Men having sex with men donor deferral risk assessment: an analysis using risk management principles
    William Leiss
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    Transfus Med Rev 22:35-57. 2008
    ..Under these circumstances, other social policy issues, relevant to the idea of changing the deferral period for MSM, become worthy of additional consideration...
  62. ncbi request reprint Disaster and emergency management: Canadian nurses' perceptions of preparedness on hospital front lines
    Tracey L O'Sullivan
    Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada
    Prehosp Disaster Med 23:s11-8. 2008
    ....
  63. pmc Exploring bias in a generalized additive model for spatial air pollution data
    Timothy Ramsay
    R Samuel McLaughlin Centre for Population Health Risk Assessment, Ottawa, Ontario, Canada
    Environ Health Perspect 111:1283-8. 2003
    ..We argue that including a nonparametric function of location in a GAM for spatial epidemiologic data can be expected to result in concurvity. As a result, we recommend caution in using the GAM to analyze this type of data...
  64. ncbi request reprint Residential pesticides and childhood leukemia: a systematic review and meta-analysis
    Michelle C Turner
    Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, ON, Canada
    Cien Saude Colet 16:1915-31. 2011
    ..Further work is needed to confirm previous findings based on self-report, to examine potential exposure-response relationships, and to assess specific pesticides and toxicologically related subgroups of pesticides in more detail...
  65. ncbi request reprint Thermal therapy, Part III: ablation techniques
    Riadh W Y Habash
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health School of Information Technology and Engineering, University of Ottawa, Ottawa, Ontario, Canada
    Crit Rev Biomed Eng 35:37-121. 2007
    ....
  66. pmc Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide
    Daniel Krewski
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health B Crit Rev 10:1-269. 2007
  67. ncbi request reprint A psychosocial risk assessment and management framework to enhance response to CBRN terrorism threats and attacks
    Louise Lemyre
    School of Psychology, Institute of Population Health, McLaughlin Centre, University of Ottawa, Ontario, Canada
    Biosecur Bioterror 3:316-30. 2005
    ....
  68. ncbi request reprint The association between sulfate air pollution and mortality at the county scale: an exploration of the impact of scale on a long-term exposure study
    Alette Willis
    Department of Geography and Environmental Studies, Carleton University, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 66:1605-24. 2003
    ..Thus, at the county scale, long-term exposure to sulfates appears to be more strongly associated with increased risk of all-cause and cardiopulmonary mortality than previously indicated by the ACS study and its reanalysis...
  69. ncbi request reprint Air pollution and public health: a guidance document for risk managers
    Lorraine Craig
    Network for Environmental Risk Assessment and Management, University of Waterloo, Waterloo, Ontario, Canada
    J Toxicol Environ Health A 71:588-698. 2008
    ....
  70. doi request reprint A risk-based classification scheme for genetically modified foods. II: Graded testing
    Eunice Chao
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, 1 Stewart Street, Ottawa, Ont, Canada K1N 6N5
    Regul Toxicol Pharmacol 52:223-34. 2008
    ..Since appropriate test methods are not currently available for all effects of concern, future research to strengthen the testing of GM foods is discussed...
  71. doi request reprint Recent advances in research on radiofrequency fields and health: 2004-2007
    Riadh W Y Habash
    R Samuel McLaughlin Center for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health B Crit Rev 12:250-88. 2009
    ..The results of the ongoing 13-country World Health Organization INTERPHONE study of mobile phones may provide important new information on the potential cancer risks associated with mobile phone use...
  72. ncbi request reprint Influence of relatively low level of particulate ar pollution on hospitalization for COPD in elderly people
    Yue Chen
    Department of Epidemiology and Community Medicine and McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Inhal Toxicol 16:21-5. 2004
    ....
  73. ncbi request reprint Residential radon in Canada: an uncertainty analysis of population and individual lung cancer risk
    Kevin P Brand
    McLauglin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Risk Anal 25:253-69. 2005
    ..This insight is applied in scaling our baseline results to obtain gender-specific estimates, as well as in simplifying and illuminating sensitivity analysis...
  74. ncbi request reprint Cancer mortality among US men and women with asthma and hay fever
    Michelle C Turner
    R Samuel McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Am J Epidemiol 162:212-21. 2005
    ..Collectively, these results suggest an inverse association between a history of allergy and cancer mortality; however, the strength of evidence for this association is limited...
  75. ncbi request reprint Obesity may increase the incidence of asthma in women but not in men: longitudinal observations from the Canadian National Population Health Surveys
    Yue Chen
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Am J Epidemiol 155:191-7. 2002
    ..1, 3.4), whereas the corresponding odds ratio of 1.1 (95% confidence interval: 0.3, 3.6) for men was not significantly different from unity. The authors concluded that obesity was related to development of asthma in women but not in men...
  76. ncbi request reprint Thermal therapy, part 1: an introduction to thermal therapy
    Riadh W Y Habash
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health School of Information Technology and Engineering, University of Ottawa, Ottawa, Ontario, Canada
    Crit Rev Biomed Eng 34:459-89. 2006
    ..The review concludes with an evaluation of human exposure risk to EM energy or the corresponding heat, trends in equipment development, and future research directions...
  77. doi request reprint Toxicity testing in the 21st century: implications for human health risk assessment
    Daniel Krewski
    University of Ottawa, Ottawa, Canada
    Risk Anal 29:474-9. 2009
    ..The present article summarizes and extends the NRC report and examines its implications for risk assessment practice...
  78. ncbi request reprint The effect of coarse ambient particulate matter on first, second, and overall hospital admissions for respiratory disease among the elderly
    Yue Chen
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Inhal Toxicol 17:649-55. 2005
    ..5 has a larger effect on respiratory admissions than PM2.5...
  79. doi request reprint An exposure-response curve for copper excess and deficiency
    Andrea Chambers
    Institute of Population Health, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health B Crit Rev 13:546-78. 2010
    ..To weigh the relative harms of deficiency and excess, it is important that the results be interpreted along with the available information on the nature of the responses that were assigned to each severity score...
  80. pmc Residential pesticides and childhood leukemia: a systematic review and meta-analysis
    Michelle C Turner
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Canada
    Environ Health Perspect 118:33-41. 2010
    ....
  81. doi request reprint Occupations and lung cancer: a population-based case-control study in British Columbia
    Nagarajkumar Yenugadhati
    R Samuel McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ontario, Canada
    J Toxicol Environ Health A 72:658-75. 2009
    ..g., medical radiation, electromagnetic fields, and cooking fumes)...
  82. doi request reprint A risk-based classification scheme for genetically modified foods. I: Conceptual development
    Eunice Chao
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, 1 Stewart Street, Ottawa, Ont, Canada KIN 6N5
    Regul Toxicol Pharmacol 52:208-22. 2008
    ..An overview of the proposed scheme is presented, as well as the application of the scheme to a hypothetical GM food...
  83. ncbi request reprint Thermal therapy, part 2: hyperthermia techniques
    Riadh W Y Habash
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health School of Information Technology and Engineering, University of Ottawa, Ottawa, Ontario, Canada
    Crit Rev Biomed Eng 34:491-542. 2006
    ..The results of combinations of other modalities such as radiotherapy or chemotherapy with hyperthermia as a new treatment strategy are summarized. The article concludes with a discussion of challenges and opportunities for the future...
  84. doi request reprint Health effects of radon: a review of the literature
    Mustafa Al-Zoughool
    McLaughlin Center for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada
    Int J Radiat Biol 85:57-69. 2009
    ..The purpose of the current review is to summarize recent literature and evaluate the weight of evidence on the adverse health effects of radon...
  85. doi request reprint A risk-based classification scheme for genetically modified foods. III: Evaluation using a panel of reference foods
    Eunice Chao
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, 1 Stewart Street, Ottawa, Ont, Canada K1N 6N5
    Regul Toxicol Pharmacol 52:235-41. 2008
    ..Specific issues and suggestions for improvements identified in the concordance study are discussed...
  86. ncbi request reprint Regulatory and nonregulatory strategies for improving children's environmental health in Canada
    Michael G Tyshenko
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario
    J Toxicol Environ Health B Crit Rev 10:143-56. 2007
    ..Recommendations for improving the existing framework for protecting and strengthening children's environmental health are proposed...
  87. ncbi request reprint Thermal therapy, Part IV: electromagnetic and thermal dosimetry
    Riadh W Y Habash
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health School of Information Technology and Engineering, University of Ottawa, Ottawa, Ontario, Canada
    Crit Rev Biomed Eng 35:123-82. 2007
    ..Various imaging techniques for guidance and monitoring necessary for clinical treatments are also discussed. The review concludes by suggesting future avenues for investigations...
  88. ncbi request reprint The effect of concurvity in generalized additive models linking mortality to ambient particulate matter
    Timothy O Ramsay
    Health Canada, Ottawa, Canada
    Epidemiology 14:18-23. 2003
    ....
  89. pmc Association between gaseous ambient air pollutants and adverse pregnancy outcomes in Vancouver, Canada
    Shiliang Liu
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, and Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Environ Health Perspect 111:1773-8. 2003
    ..0 ppm increase) during the first month of pregnancy. In conclusion, relatively low concentrations of gaseous air pollutants are associated with adverse effects on birth outcomes in populations experiencing diverse air pollution profiles...
  90. ncbi request reprint Chronic obstructive pulmonary disease is associated with lung cancer mortality in a prospective study of never smokers
    Michelle C Turner
    McLaughlin Center for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Canada
    Am J Respir Crit Care Med 176:285-90. 2007
    ..Several studies have suggested that previous lung disease may increase the risk of lung cancer. It is important to clarify the association between previous lung disease and lung cancer risk in the general population...
  91. ncbi request reprint Health risks of electromagnetic fields. Part I: Evaluation and assessment of electric and magnetic fields
    Riadh W Y Habash
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Crit Rev Biomed Eng 31:141-95. 2003
    ..Further research is needed to clarify the ambiguous findings from present studies and to determine if EMF exposure poses a health risk...
  92. ncbi request reprint Dietary risk factors for testicular carcinoma
    Michael J Garner
    R Samuel McLaughlin Center for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada
    Int J Cancer 106:934-41. 2003
    ..87; 95% confidence interval [CI] 1.22-2.86; p-trend < 0.001), is associated with an elevated risk of testicular cancer in Canadian males...
  93. ncbi request reprint Association between maternal exposure to ambient air pollutants during pregnancy and fetal growth restriction
    Shiliang Liu
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, 1 Stewart Street, Ontario, Canada
    J Expo Sci Environ Epidemiol 17:426-32. 2007
    ..Our findings add to the emerging body of evidence that exposure to relatively low levels of ambient air pollutants in urban areas during pregnancy is associated with adverse effects on fetal growth...
  94. ncbi request reprint Health risks of electromagnetic fields. Part II: Evaluation and assessment of radio frequency radiation
    Riadh W Y Habash
    McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada
    Crit Rev Biomed Eng 31:197-254. 2003
    ..Additional research is needed to clarify possible associations between RFR and biological effects noted in some studies. Particular attention should be directed toward long-term, low-level exposure to RFR...
  95. ncbi request reprint An overview of the association between allergy and cancer
    Michelle C Turner
    R Samuel McLaughlin Center for Population Health Risk Assessment, University of Ottawa, Canada
    Int J Cancer 118:3124-32. 2006
    ..There is also a need for further basic research to clarify a potential mechanism, should an association exist...
  96. ncbi request reprint Use of generalized linear mixed models in analyzing mutant frequency data from the transgenic mouse assay
    K Y Fung
    Department of Mathematics and Statistics, University of Windsor, Ontario, Canada
    Environ Mol Mutagen 31:48-54. 1998
    ..g., animals, packages, and plates) can be estimated and tested for significance. Data previously reported in the literature involving the lacl gene from the Big Blue mouse are used to illustrate the proposed method...
  97. ncbi request reprint Sex-related interactive effect of smoking and household pets on asthma incidence
    Y Chen
    Dept of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Eur Respir J 20:1162-6. 2002
    ..These results indicate that smoking, having pets at home and other environmental factors can partly explain asthma morbidity among female Canadians...
  98. ncbi request reprint Interaction between two carcinogens in the two-stage clonal expansion model of carcinogenesis
    J Zielinski
    Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario
    J Epidemiol Biostat 6:219-28. 2001
    ..1991) for an approximate form of the two-stage model, which predicts much higher values of the index of synergy S than the exact form of the model when promotion is involved...
  99. doi request reprint Patterns of pregnancy exposure to prescription FDA C, D and X drugs in a Canadian population
    S W Wen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON, Canada
    J Perinatol 28:324-9. 2008
    ..To examine prescription Food and Drug Administration (FDA) C, D and X drugs in general obstetric population...
  100. ncbi request reprint Statistical analysis of lacZ mutant frequency data from MutaMouse mutagenicity assays
    K Y Fung
    Department of Mathematics and Statistics, University of Windsor, Ontario, Canada
    Mutagenesis 13:249-55. 1998
    ..A logistical model was used to further describe the dose-response relationship observed in N-nitrosodibenzylamine-treated liver tissue...
  101. ncbi request reprint Adjusting for measurement error in the Cox proportional hazards regression model
    R Mallick
    School of Mathematics and Statistics, Carleton University, Ottawa, Ontario, Canada K1S 5B6
    J Cancer Epidemiol Prev 7:155-64. 2002
    ..It is well-known that random measurement error leads to downward bias in estimates of risk, and overstatement of the precision of such estimates...