M Krahn

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Potential cost-effectiveness of a preventive hepatitis C vaccine in high risk and average risk populations in Canada
    Murray D Krahn
    Department of Medicine, University Health Network, Department of Health Policy, Management and Evaluation, University of Toronto, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 1C4
    Vaccine 23:1549-58. 2005
  2. ncbi request reprint A review and meta-analysis of prostate cancer utilities
    Karen E Bremner
    Toronto General Research Institute University Health Network, Canada
    Med Decis Making 27:288-98. 2007
  3. pmc Cohort effects in dynamic models and their impact on vaccination programmes: an example from hepatitis A
    Arni S R Srinivasa Rao
    Department of Mathematics and Statistics, University of Guelph, Guelph, Canada
    BMC Infect Dis 6:174. 2006
  4. pmc A review of interventions triggered by hepatitis A infected food-handlers in Canada
    Andrea C Tricco
    Epidemiology and Biostatistics, GlaxoSmithKline Canada, Mississauga, Ontario, Canada
    BMC Health Serv Res 6:157. 2006
  5. ncbi request reprint Estimating the prognosis of hepatitis C patients infected by transfusion in Canada between 1986 and 1990
    Murray Krahn
    Toronto General Hospital, ES9 408, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    Med Decis Making 24:20-9. 2004
  6. ncbi request reprint Economic issues in the use of office spirometry for lung health assessment
    Murray Krahn
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Can Respir J 10:320-6. 2003
  7. ncbi request reprint Patient and community preferences for outcomes in prostate cancer: implications for clinical policy
    Murray Krahn
    Department of Medicine And Programme in Clinical Epidemiology and Health Care Research, University of Toronto, Ontario, Candada
    Med Care 41:153-64. 2003
  8. ncbi request reprint Responsiveness of disease-specific and generic utility instruments in prostate cancer patients
    Murray Krahn
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Qual Life Res 16:509-22. 2007
  9. ncbi request reprint Construction of the Patient-Oriented Prostate Utility Scale (PORPUS): a multiattribute health state classification system for prostate cancer
    M Krahn
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Clin Epidemiol 53:920-30. 2000
  10. doi request reprint Impact of androgen-deprivation therapy on cognitive function in men with nonmetastatic prostate cancer
    Shabbir M H Alibhai
    University Health Network, Toronto, Ontario, Canada
    J Clin Oncol 28:5030-7. 2010

Detail Information

Publications62

  1. ncbi request reprint Potential cost-effectiveness of a preventive hepatitis C vaccine in high risk and average risk populations in Canada
    Murray D Krahn
    Department of Medicine, University Health Network, Department of Health Policy, Management and Evaluation, University of Toronto, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 1C4
    Vaccine 23:1549-58. 2005
    ..These results provide encouragement to vaccine developers that a vaccine that is moderately effective and reasonably priced should not face economic barriers to implementation and will be attractive to third party payers...
  2. ncbi request reprint A review and meta-analysis of prostate cancer utilities
    Karen E Bremner
    Toronto General Research Institute University Health Network, Canada
    Med Decis Making 27:288-98. 2007
    ..Health-related quality of life is a key issue in prostate cancer (PC) management. The authors summarized published utilities for common health-related quality of life outcomes of PC and determined how methodological factors affect them...
  3. pmc Cohort effects in dynamic models and their impact on vaccination programmes: an example from hepatitis A
    Arni S R Srinivasa Rao
    Department of Mathematics and Statistics, University of Guelph, Guelph, Canada
    BMC Infect Dis 6:174. 2006
    ..As a result, age-stratified seroprevalence profiles often differ from what would be expected from constant infection rates...
  4. pmc A review of interventions triggered by hepatitis A infected food-handlers in Canada
    Andrea C Tricco
    Epidemiology and Biostatistics, GlaxoSmithKline Canada, Mississauga, Ontario, Canada
    BMC Health Serv Res 6:157. 2006
    ..We undertook a systematic review of such incidents to evaluate the extent of viral transmission through food contamination and the scope of post-exposure prophylaxis (PEP) interventions...
  5. ncbi request reprint Estimating the prognosis of hepatitis C patients infected by transfusion in Canada between 1986 and 1990
    Murray Krahn
    Toronto General Hospital, ES9 408, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    Med Decis Making 24:20-9. 2004
    ..To develop a natural history model for chronic hepatitis C virus (HCV) infection to determine allocation of compensatory funds to Canadians who acquired HCV through the blood supply from 1986 through 1990...
  6. ncbi request reprint Economic issues in the use of office spirometry for lung health assessment
    Murray Krahn
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Can Respir J 10:320-6. 2003
    ..Such analyses should play a role in future clinical policy making. Even modest quit rates attributable to screening spirometry may result in highly favourable cost effectiveness ratios...
  7. ncbi request reprint Patient and community preferences for outcomes in prostate cancer: implications for clinical policy
    Murray Krahn
    Department of Medicine And Programme in Clinical Epidemiology and Health Care Research, University of Toronto, Ontario, Candada
    Med Care 41:153-64. 2003
    ..Utilities can be elicited directly from patients using standard techniques, or indirectly, using questionnaires that incorporate preference weights from community members...
  8. ncbi request reprint Responsiveness of disease-specific and generic utility instruments in prostate cancer patients
    Murray Krahn
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Qual Life Res 16:509-22. 2007
    ..Preferences (utilities) for health outcomes have an important role in decisions about prostate cancer screening and treatment. The responsiveness of utility instruments has not been evaluated...
  9. ncbi request reprint Construction of the Patient-Oriented Prostate Utility Scale (PORPUS): a multiattribute health state classification system for prostate cancer
    M Krahn
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Clin Epidemiol 53:920-30. 2000
    ..In conjunction with a set of utility weights, it may be used to develop a health status index, to improve utility measurement in patients, and to serve as a short psychometric (nonutility) instrument...
  10. doi request reprint Impact of androgen-deprivation therapy on cognitive function in men with nonmetastatic prostate cancer
    Shabbir M H Alibhai
    University Health Network, Toronto, Ontario, Canada
    J Clin Oncol 28:5030-7. 2010
    ..To evaluate the effects of androgen-deprivation therapy (ADT) on cognitive function in men with nonmetastatic prostate cancer (PC)...
  11. doi request reprint Impact of androgen-deprivation therapy on physical function and quality of life in men with nonmetastatic prostate cancer
    Shabbir M H Alibhai
    University Health Network, Toronto, Ontario, Canada
    J Clin Oncol 28:5038-45. 2010
    ..This prospective longitudinal study evaluated the effect of androgen deprivation therapy (ADT) on objective and self-reported physical function...
  12. doi request reprint Immigrant patients with chronic hepatitis C and advanced fibrosis have a higher risk of hepatocellular carcinoma
    W Chen
    Toronto Health Economics and Technology Assessment THETA Collaborative, University of Toronto, Canada
    J Viral Hepat 19:574-80. 2012
    ..37; P = 0.318) after adjusting for age and type 2 diabetes. Older age and higher prevalence of type 2 diabetes accounted for the increased risk of HCC among immigrant patients with CHC and advanced fibrosis...
  13. doi request reprint Levels of sex hormones have limited effect on cognition in older men with or without prostate cancer
    S M H Alibhai
    Department of Medicine, University Health Network, Canada
    Crit Rev Oncol Hematol 73:167-75. 2010
    ..Although cognitive function was not generally related to sex hormone levels in older men, there may be a weak association with working memory. These results may help guide future studies...
  14. ncbi request reprint The cost effectiveness of ACE inhibitors as first-line antihypertensive therapy
    Alain J Nordmann
    The Programme in Clinical Epidemiology and Health Care Research, University of Toronto, Toronto, Ontario, Canada
    Pharmacoeconomics 21:573-85. 2003
    ..Current hypertension guidelines differ in their recommendations for first-line antihypertensive therapy...
  15. ncbi request reprint The cost effectiveness of rofecoxib and celecoxib in patients with osteoarthritis or rheumatoid arthritis
    Andreas Maetzel
    University Health Network, Toronto, Ontario, Canada
    Arthritis Rheum 49:283-92. 2003
    ..To evaluate the cost effectiveness of the cyclooxygenase 2 (COX-2) selective nonsteroidal antiinflammatory drug (NSAID) rofecoxib compared with naproxen and the COX-2 NSAID celecoxib compared with ibuprofen and diclofenac...
  16. ncbi request reprint Reliability and validity of the PORPUS, a combined psychometric and utility-based quality-of-life instrument for prostate cancer
    Paul Ritvo
    York University, and Cancer Care Ontario, Division of Preventive Oncology, 620 University Ave, 1236, Toronto, Ontario M5G, Canada
    J Clin Epidemiol 58:466-74. 2005
    ..In this study we developed and tested these two forms of quality-of-life instruments, both based on a single, validated, health classification system...
  17. ncbi request reprint Improving the accuracy of long-term prognostic estimates in hepatitis C virus infection
    Q Yi
    Department of Biostatistics, University Health Network, The University of Toronto, Toronto, Ontario, Canada
    J Viral Hepat 11:166-74. 2004
    ..Application of the method supports the hypothesis that rates of fibrosis vary between stages...
  18. pmc Costs and cost-effectiveness of a universal, school-based hepatitis B vaccination program
    M Krahn
    Department of Medicine, University of Toronto, Ontario, Canada
    Am J Public Health 88:1638-44. 1998
    ..This study evaluated the costs and cost-effectiveness of a school-based grade 6 universal vaccination program against hepatitis B...
  19. doi request reprint Treatment of hepatitis C infection for current or former substance abusers in a community setting
    A John-Baptiste
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
    J Viral Hepat 16:557-67. 2009
    ..Rates of completion and response are comparable to non-substance abusing populations. Antiviral therapy for HCV infection can be successful within the context of ongoing care for substance abuse for carefully selected patients...
  20. ncbi request reprint Indications for interferon/ribavirin therapy in hepatitis C patients: findings from a survey of Canadian hepatologists
    Peter Wang
    Toronto General Hospital, Toronto, Canada
    Can J Gastroenterol 17:183-6. 2003
    ..To survey practising hepatologists about their attitudes and practices regarding interferon and ribavirin combination therapy for hepatitis C (HCV) patients in Canada...
  21. doi request reprint The half-cycle correction explained: two alternative pedagogical approaches
    David M J Naimark
    Division of Nephrology, Sunny brook and Women s College Health Sciences Centre, Toronto, Canada
    Med Decis Making 28:706-12. 2008
    ..Elements of adult learning theory are discussed, which may help the instructor to choose which approach to employ. Implementation of the half-cycle correction in commonly used decision-analytic software is also discussed...
  22. doi request reprint Identifying the best treatment among common nonsurgical neck pain treatments: a decision analysis
    Gabrielle van der Velde
    Institute for Work and Health, Toronto, ON, Canada
    Spine (Phila Pa 1976) 33:S184-91. 2008
    ..Decision analysis...
  23. ncbi request reprint Life expectancy gains and cost-effectiveness of implantable cardioverter/defibrillators for the primary prevention of sudden cardiac death in patients with hypertrophic cardiomyopathy
    John J You
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am Heart J 154:899-907. 2007
    ..Sudden cardiac death (SCD) is a devastating complication of hypertrophic cardiomyopathy (HCM). The optimal strategy for the primary prevention of SCD in HCM remains controversial...
  24. ncbi request reprint Prostate cancers scored as Gleason 6 on prostate biopsy are frequently Gleason 7 tumors at radical prostatectomy: implication on outcome
    Jehonathan H Pinthus
    Prostate Cancer Center, Princess Margaret Hospital, 620 University Avenue, Toronto, Ontario M5G 2M9, Canada
    J Urol 176:979-84; discussion 984. 2006
    ....
  25. ncbi request reprint Cost-effectiveness analyses of hepatitis A vaccine: a systematic review to explore the effect of methodological quality on the economic attractiveness of vaccination strategies
    Andrea M Anonychuk
    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Pharmacoeconomics 26:17-32. 2008
    ..Methodological quality varied across studies. Major methodological flaws included inappropriate model type, comparator, incidence estimate and inclusion/exclusion of costs...
  26. doi request reprint Prevalence and predictors of obesity among individuals with positive hepatitis C antibody in a tertiary referral clinic
    Wendong Chen
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto Western Hospital, Toronto, Ont, Canada M5T 2S8
    J Hepatol 49:711-7. 2008
    ..To determine the prevalence of obesity and investigate factors associated with obesity in a hepatitis C antibody positive clinic population...
  27. doi request reprint The next step in guideline development: incorporating patient preferences
    Murray Krahn
    Toronto Health Economics and Technology Assessment Collaborative, Toronto General Research Institute, and University of Toronto, Toronto, Ontario, Canada
    JAMA 300:436-8. 2008
  28. doi request reprint Acute appendicitis in young children: cost-effectiveness of US versus CT in diagnosis--a Markov decision analytic model
    Michael J Wan
    Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, ON, Canada
    Radiology 250:378-86. 2009
    ..To compare the cost-effectiveness of different imaging strategies in the diagnosis of pediatric appendicitis by using a decision analytic model...
  29. ncbi request reprint Health-state utilities and quality of life in hepatitis C patients
    Christopher A K Y Chong
    Faculty of Medicine, University of Toronto, Ontario, Canada
    Am J Gastroenterol 98:630-8. 2003
    ..Currently, utilities for hepatitis C virus (HCV)-infected patients have been estimated using expert judgments. The purpose of this study was to elicit HCV utilities directly from patients...
  30. doi request reprint Association of temporal trends in risk factors and treatment uptake with coronary heart disease mortality, 1994-2005
    Harindra C Wijeysundera
    Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    JAMA 303:1841-7. 2010
    ..Coronary heart disease (CHD) mortality has declined substantially in Canada since 1994...
  31. pmc Feasibility of internet-based health-related quality of life data collection in a large patient cohort
    Sacha Bhinder
    Faculty of Medicine, University of Toronto, Toronto, Canada
    J Med Internet Res 12:e35. 2010
    ..Internet-based HRQOL questionnaires are a potential solution, allowing home data collection with immediate storage in a central database...
  32. ncbi request reprint Utility-based Quality of Life measures in Alzheimer's disease
    Gary Naglie
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Qual Life Res 15:631-43. 2006
    ....
  33. ncbi request reprint Decision analysis in aerospace medicine: costs and benefits of a hyperbaric facility in space
    Ava John-Baptiste
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Aviat Space Environ Med 77:434-42; discussion 442-3. 2006
    ..We illustrate the use of decision analysis to compare a hyperbaric oxygen (HBO) chamber to currently available therapy for DCS treatment on the ISS...
  34. ncbi request reprint Quality of life in early Parkinson's disease: impact of dyskinesias and motor fluctuations
    Connie Marras
    Division of Neurology, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Mov Disord 19:22-8. 2004
    ..We conclude that motor complications that occur within the first 4 years of treatment of PD do not have a significant negative effect on quality of life as measured by a visual analogue scale for most patients...
  35. doi request reprint Management of decreased bone mineral density in men starting androgen-deprivation therapy for prostate cancer
    Abbas H Panju
    Department of Medicine, University Health Network, Toronto, Ontario, Canada
    BJU Int 103:753-7. 2009
    ....
  36. pmc The effect of English language proficiency on length of stay and in-hospital mortality
    Ava John-Baptiste
    Division of General Internal Medicine, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Gen Intern Med 19:221-8. 2004
    ..In ambulatory care settings, patients with limited English proficiency receive lower quality of care. Limited information is available describing outcomes for inpatients...
  37. ncbi request reprint Vaccines in the public eye
    Paul Ritvo
    School of Kinesiology and Health Sciences and Department of Psychology, York University, Toronto, Ontario M3J 1P3, Canada
    Nat Med 11:S20-4. 2005
    ..As a result, they have received much recent attention in the media that has exposed some of the challenges involved in optimally using vaccine technology...
  38. pmc Economic appraisal of Ontario's Universal Influenza Immunization Program: a cost-utility analysis
    Beate Sander
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
    PLoS Med 7:e1000256. 2010
    ..This is the first large-scale program of its kind worldwide. The objective of this study was to conduct an economic appraisal of Ontario's UIIP compared to a targeted influenza immunization program (TIIP)...
  39. doi request reprint Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian Experience
    Beate Sander
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
    Vaccine 28:6210-20. 2010
    ....
  40. pmc Prescribing patterns for Alzheimer disease: survey of Canadian family physicians
    Melinda Hillmer
    Faculty of Medicine, University of Toronto, Ontario
    Can Fam Physician 52:208-9. 2006
    ..To describe Canadian family physicians' prescribing practices with regard to Alzheimer disease (AD)...
  41. ncbi request reprint Content validity for dementia of three generic preference based health related quality of life instruments
    Michel Silberfeld
    Department of Psychiatry, Baycrest Centre for Geriatric Care, University of Toronto, Ontario, Canada
    Qual Life Res 11:71-9. 2002
    ..Compared to the respondent generated attributes all three utility-based quality of life instruments have important shortcomings in content validity...
  42. ncbi request reprint Kidney transplantation in the elderly: a decision analysis
    Sarbjit V Jassal
    Division of Nephrology, University Health Network, Toronto, Ontario, Canada
    J Am Soc Nephrol 14:187-96. 2003
    ..Prolonged waiting times dramatically decrease the clinical benefits and economic attractiveness of transplantation, suggesting that living donor transplantation may be of particular benefit in this population...
  43. doi request reprint Economics of preventing premature mortality and impaired cognitive development in children through home-fortification: a health policy perspective
    Waseem Sharieff
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    Int J Technol Assess Health Care 24:303-11. 2008
    ..Zinc supplementation may prevent morbidity and mortality related to diarrheal illnesses, and iron supplementation may improve cognitive development, in children...
  44. ncbi request reprint Is there age bias in the treatment of localized prostate carcinoma?
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Cancer 100:72-81. 2004
    ..Previous studies have evaluated the influence of age and comorbidity, but to the authors' knowledge not RLE, on actual treatment decisions...
  45. ncbi request reprint The ten-year rule revisited: accuracy of clinicians' estimates of life expectancy in patients with localized prostate cancer
    Murray D Krahn
    Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada
    Urology 60:258-63. 2002
    ....
  46. ncbi request reprint Continued undertreatment of older men with localized prostate cancer
    Kevin L Schwartz
    University of Toronto, School of Medicine, Toronto, Ontario, Canada
    Urology 62:860-5. 2003
    ..To explore the association among patient factors (age, comorbidity), disease-specific factors (stage, Gleason score), and suboptimal initial treatment in a cohort of men with localized prostate cancer...
  47. ncbi request reprint Do older men benefit from curative therapy of localized prostate cancer?
    Shabbir M H Alibhai
    University Health Network, Room ENG 233, 200 Elizabeth St, Toronto, Ontario, Canada M5G 2C4
    J Clin Oncol 21:3318-27. 2003
    ..We estimated life expectancy (LE) and quality-adjusted life expectancy (QALE) associated with available treatments for localized prostate cancer in men aged >/= 65 years, adjusting for Gleason score, patient preferences, and comorbidity...
  48. ncbi request reprint Delay in surgical therapy for clinically localized prostate cancer and biochemical recurrence after radical prostatectomy
    Robert K Nam
    Division of Urology, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Can J Urol 10:1891-8. 2003
    ..We examined whether delay from diagnosis for patients undergoing surgery for clinically localized prostate cancer affects cancer cure rates...
  49. pmc Preferences of husbands and wives for outcomes of prostate cancer screening and treatment
    Robert J Volk
    Department of Family and Community Medicine, Baylor College of Medicine, Houston, Texas 77098 3915, USA
    J Gen Intern Med 19:339-48. 2004
    ..To explore the preferences of male primary care patients and their spouses for the outcomes of prostate cancer screening and treatment, and quality of life with metastatic prostate cancer...
  50. ncbi request reprint An unadjusted NNT was a moderately good predictor of health benefit
    Christopher A K Y Chong
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Clin Epidemiol 59:224-33. 2006
    ..Whether the number needed to treat (NNT) is sufficiently precise to use in clinical practice remains unclear. We compared unadjusted NNTs to quality-adjusted life years (QALYs) gained, a more comprehensive measures of health benefit...
  51. pmc Predictors of antiviral therapy in a post-transfusion cohort of hepatitis C patients
    Maciej Witkos
    Department of Health Policy, Management and Evaluation, University of Toronto, Toronto General Hospital, Ontario, Canada
    Can J Gastroenterol 20:107-11. 2006
    ..The efficacy of therapy has recently improved with the addition of ribavirin and pegylated interferon. The aim of the present study was to identify the clinical, socioeconomic and health-system predictors of antiviral treatment for HCV...
  52. ncbi request reprint Rethinking 30-day mortality risk after radical prostatectomy
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Urology 68:1057-60. 2006
    ..Although radical prostatectomy (RP) is associated with greater 30-day mortality in older men, the magnitude of the excess risk in older age groups compared with younger ones has not been well characterized...
  53. ncbi request reprint 30-day mortality and major complications after radical prostatectomy: influence of age and comorbidity
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Canada
    J Natl Cancer Inst 97:1525-32. 2005
    ..Prior studies have suggested an increased risk of short-term complications among older men who underwent radical prostatectomy, but these studies did not adjust for comorbidity...
  54. pmc Management of solitary 1 cm to 2 cm liver nodules in patients with compensated cirrhosis: a decision analysis
    Karen E Bremner
    Toronto General Research Institute, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Can J Gastroenterol 21:491-500. 2007
    ..Alternative strategies are immediate treatment or observation until disease progression occurs...
  55. ncbi request reprint Marker states and a health state prompt provide modest improvements in the reliability and validity of the standard gamble and rating scale in prostate cancer patients
    Karen E Bremner
    Toronto General Hospital, University Health Network, Toronto, ON, Canada
    Qual Life Res 16:1665-75. 2007
    ..To evaluate the combined effect of marker states and a prompt on the reliability and validity of direct utility assessment...
  56. ncbi request reprint Azathioprine or ileocolic resection for steroid-dependent terminal ileal Crohn's disease? A Markov analysis
    Erin D Kennedy
    Department of Surgery and Medicine, University of Toronto, the Samuel Lunenfield Research Institute, Mount Sinai Hospital, Toronto, Canada
    Dis Colon Rectum 47:2120-30. 2004
    ....
  57. ncbi request reprint The association between patient age and prostate cancer stage and grade at diagnosis
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, 200 Elizabeth Street, Toronto, Ontario M50 2C4, Canada
    BJU Int 94:303-6. 2004
    ..To investigate the association of age with prostate cancer stage and grade, as the latter factors at the time of diagnosis influence management and prognosis, with some studies suggesting that they may change as a function of patient age...
  58. doi request reprint Is there an optimal comorbidity index for prostate cancer?
    Shabbir M H Alibhai
    Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada
    Cancer 112:1043-50. 2008
    ..Comorbidity is an important consideration in oncology practice, particularly among older patients. Although a variety of comorbidity indices have been employed in research studies, it is unclear whether any one index is preferred...
  59. ncbi request reprint Cost comparison of genetic and clinical screening in families with hereditary hemorrhagic telangiectasia
    Justine H Cohen
    Department of Medicine, Division of Respiratory Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Am J Med Genet A 137:153-60. 2005
    ....
  60. pmc Factors associated with the high cost of liver transplantation in adults
    Mark C Taylor
    Department of Surgery, University of Manitoba, St Boniface General Hospital, Winnipeg, Man
    Can J Surg 45:425-34. 2002
    ..To determine the overall direct cost of liver transplantation in Canadian adults and to identify the factors that are associated with high cost...
  61. ncbi request reprint The role of the ossific nucleus in the treatment of established hip dislocation
    Andreas Roposch
    Department of Orthopaedic Surgery, Great Ormond Street Hospital for Children, London, UK
    Clin Orthop Relat Res 449:295-302. 2006
    ..Level of Evidence: Economic and Decision Analyses, Level II-1. See the Guidelines for Authors for a complete description of levels of evidence...
  62. doi request reprint Estimation of stage-specific fibrosis progression rates in chronic hepatitis C virus infection: a meta-analysis and meta-regression
    Hla Hla Thein
    University Health Network, Division of Clinical Decision Making and Health Care Research, Toronto, Ontario, Canada
    Hepatology 48:418-31. 2008
    ..Estimates of progression to cirrhosis from studies conducted in clinical settings were lower than previous estimates...