A D Krahn

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi request reprint Utility and cost effectiveness of temporary pacing using active fixation leads and an externally placed reusable permanent pacemaker
    Stephen M Chihrin
    The Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am J Cardiol 98:1613-5. 2006
  2. ncbi request reprint Cardiac monitoring in patients with syncope: making that elusive diagnosis
    Rajesh Subbiah
    London Health Sciences Centre, University Campus, C6 113, 339 Windermere Road, London, Ontario, Canada, N6A 5A5
    Curr Cardiol Rev 9:299-307. 2013
  3. doi request reprint Empiric pacemaker compared with a monitoring strategy in patients with syncope and bifascicular conduction block--rationale and design of the Syncope: Pacing or Recording in ThE Later Years (SPRITELY) study
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, ON, Canada
    Europace 14:1044-8. 2012
  4. doi request reprint Sentinel symptoms in patients with unexplained cardiac arrest: from the cardiac arrest survivors with preserved ejection fraction registry (CASPER)
    Andrew D Krahn
    University of Western Ontario, London, Ontario, Canada Hamilton Health Sciences Center, Hamilton, Ontario, Canada
    J Cardiovasc Electrophysiol 23:60-6. 2012
  5. pmc Using the net benefit regression framework to construct cost-effectiveness acceptability curves: an example using data from a trial of external loop recorders versus Holter monitoring for ambulatory monitoring of "community acquired" syncope
    Jeffrey S Hoch
    Centre for Research on Inner City Health, St Michael s Hospital, Toronto, Canada
    BMC Health Serv Res 6:68. 2006
  6. ncbi request reprint Use of the implantable loop recorder in patients with unexplained syncope
    A D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Minerva Cardioangiol 51:21-7. 2003
  7. doi request reprint Utilization of a national network for rapid response to the Medtronic Fidelis lead advisory: the Canadian Heart Rhythm Society Device Advisory Committee
    Andrew D Krahn
    London Health Sciences Centre University Campus, London, Ontario, Canada
    Heart Rhythm 6:474-7. 2009
  8. doi request reprint Systematic assessment of patients with unexplained cardiac arrest: Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER)
    Andrew D Krahn
    University of Western Ontario, London, Ontario, Canada
    Circulation 120:278-85. 2009
  9. ncbi request reprint Biventricular pacing improves quality of life and exercise tolerance in patients with heart failure and intraventricular conduction delay
    Andrew D Krahn
    London Health Sciences Centre, University Campus, London, Canada
    Can J Cardiol 18:380-7. 2002
  10. doi request reprint Anticoagulation of patients on chronic warfarin undergoing arrhythmia device surgery: wide variability of perioperative bridging in Canada
    Andrew D Krahn
    University of Western Ontario, London, Ontario, Canada, Hamilton Health Sciences Center, Hamilton, Ontario, Canada
    Heart Rhythm 6:1276-9. 2009

Detail Information

Publications103 found, 100 shown here

  1. ncbi request reprint Utility and cost effectiveness of temporary pacing using active fixation leads and an externally placed reusable permanent pacemaker
    Stephen M Chihrin
    The Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am J Cardiol 98:1613-5. 2006
    ..In conclusion, temporary pacing using this technique is a reliable and comfortable alternative to traditional temporary pacing and appears to be a cost-effective temporary pacing option after 18 hours...
  2. ncbi request reprint Cardiac monitoring in patients with syncope: making that elusive diagnosis
    Rajesh Subbiah
    London Health Sciences Centre, University Campus, C6 113, 339 Windermere Road, London, Ontario, Canada, N6A 5A5
    Curr Cardiol Rev 9:299-307. 2013
    ..We provide a comprehensive review of these devices and discuss strategies on how to reach the elusive diagnosis based on current evidencebased recommendations. ..
  3. doi request reprint Empiric pacemaker compared with a monitoring strategy in patients with syncope and bifascicular conduction block--rationale and design of the Syncope: Pacing or Recording in ThE Later Years (SPRITELY) study
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, ON, Canada
    Europace 14:1044-8. 2012
    ..This study seeks to identify the optimal management strategy for patients with syncope in the context of bifascicular block and preserved left ventricular systolic function...
  4. doi request reprint Sentinel symptoms in patients with unexplained cardiac arrest: from the cardiac arrest survivors with preserved ejection fraction registry (CASPER)
    Andrew D Krahn
    University of Western Ontario, London, Ontario, Canada Hamilton Health Sciences Center, Hamilton, Ontario, Canada
    J Cardiovasc Electrophysiol 23:60-6. 2012
    ..We explored the symptom history of patients with apparently unexplained cardiac arrest to determine the frequency of sentinel symptoms...
  5. pmc Using the net benefit regression framework to construct cost-effectiveness acceptability curves: an example using data from a trial of external loop recorders versus Holter monitoring for ambulatory monitoring of "community acquired" syncope
    Jeffrey S Hoch
    Centre for Research on Inner City Health, St Michael s Hospital, Toronto, Canada
    BMC Health Serv Res 6:68. 2006
    ..The net benefit regression framework (NBRF) allows cost-effectiveness analysis to be done in a simple regression framework. The objective of the paper is to illustrate how net benefit regression can be used to construct a CEAC...
  6. ncbi request reprint Use of the implantable loop recorder in patients with unexplained syncope
    A D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Minerva Cardioangiol 51:21-7. 2003
    ....
  7. doi request reprint Utilization of a national network for rapid response to the Medtronic Fidelis lead advisory: the Canadian Heart Rhythm Society Device Advisory Committee
    Andrew D Krahn
    London Health Sciences Centre University Campus, London, Ontario, Canada
    Heart Rhythm 6:474-7. 2009
    ..The Canadian Heart Rhythm Society (CHRS) Device Advisory Committee was commissioned in 2006 to develop a mechanism for responding to advisories regarding cardiac rhythm device and lead performance...
  8. doi request reprint Systematic assessment of patients with unexplained cardiac arrest: Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER)
    Andrew D Krahn
    University of Western Ontario, London, Ontario, Canada
    Circulation 120:278-85. 2009
    ..Provocative testing to unmask a phenotype is often necessary to detect primary electrical disease, direct genetic testing, and perform family screening...
  9. ncbi request reprint Biventricular pacing improves quality of life and exercise tolerance in patients with heart failure and intraventricular conduction delay
    Andrew D Krahn
    London Health Sciences Centre, University Campus, London, Canada
    Can J Cardiol 18:380-7. 2002
    ..Identification of patients most likely to respond to biventricular pacing was not possible...
  10. doi request reprint Anticoagulation of patients on chronic warfarin undergoing arrhythmia device surgery: wide variability of perioperative bridging in Canada
    Andrew D Krahn
    University of Western Ontario, London, Ontario, Canada, Hamilton Health Sciences Center, Hamilton, Ontario, Canada
    Heart Rhythm 6:1276-9. 2009
    ..In patients undergoing cardiac rhythm device surgery, it is common practice to discontinue oral anticoagulation and to perform heparin bridging in order to reduce the risk of bleeding and minimize the risk of thromboembolic events...
  11. doi request reprint Derivation and validation of a simple exercise-based algorithm for prediction of genetic testing in relatives of LQTS probands
    Raymond W Sy
    University of Western Ontario, London, Canada
    Circulation 124:2187-94. 2011
    ..The accuracy of a simple algorithm that incorporates resting and exercise ECG parameters for screening LQTS in asymptomatic relatives was evaluated, with genetic testing as the gold standard...
  12. ncbi request reprint Insertable loop recorder use for detection of intermittent arrhythmias
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Pacing Clin Electrophysiol 27:657-64. 2004
    ..The implantable loop recorder is most useful in patients with infrequent unexplained syncope when noninvasive testing is negative...
  13. doi request reprint Predictors of short-term complications after implantable cardioverter-defibrillator replacement: results from the Ontario ICD Database
    Andrew D Krahn
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Circ Arrhythm Electrophysiol 4:136-42. 2011
    ..In addition, replacement may be a discretionary decision in the context of an advisory or borderline device performance and patient, device, and implanter factors that predict adverse outcome may assist in clinical decision-making...
  14. ncbi request reprint Cost implications of testing strategy in patients with syncope: randomized assessment of syncope trial
    Andrew D Krahn
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    J Am Coll Cardiol 42:495-501. 2003
    ..We sought to assess the cost implications of two investigation strategies in patients with unexplained syncope...
  15. ncbi request reprint Diminishing proportional risk of sudden death with advancing age: implications for prevention of sudden death
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 147:837-40. 2004
    ..We sought to determine the effect of advancing age on the mode of death in the Amiodarone Trialists Metanalysis...
  16. ncbi request reprint Use of the implantable loop recorder in evaluation of patients with unexplained syncope
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    J Cardiovasc Electrophysiol 14:S70-3. 2003
    ....
  17. ncbi request reprint Diagnosis of unexplained cardiac arrest: role of adrenaline and procainamide infusion
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Canada
    Circulation 112:2228-34. 2005
    ..Although these may be evident on the ECG, long-term monitoring or provocative testing is often necessary to unmask latent primary electrical disease...
  18. ncbi request reprint Physiologic pacing in patients with obstructive sleep apnea: a prospective, randomized crossover trial
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    J Am Coll Cardiol 47:379-83. 2006
    ..This study was designed to assess the impact of prevention of bradycardia with physiologic pacing on the severity of obstructive sleep apnea...
  19. doi request reprint Cost of preimplantation cardiac imaging in patients referred for a primary-prevention implantable cardioverter-defibrillator
    Andrew D Krahn
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Am J Cardiol 102:588-92. 2008
    ..In conclusion, verification of ejection fraction identified a significant proportion of patients who were not eligible for an ICD...
  20. doi request reprint Outcome of the Fidelis implantable cardioverter-defibrillator lead advisory: a report from the Canadian Heart Rhythm Society Device Advisory Committee
    Andrew D Krahn
    London Health Sciences Center, University Campus, 339 Windermere Road, London, Ontario, Canada N6A 5A5
    Heart Rhythm 5:639-42. 2008
    ..The Medtronic Sprint Fidelis family of leads has recently been the subject of a widespread advisory. Lead failure rates are estimated at 2.3% at 30 months, 2.6 times the failure rate of the reference Medtronic 6947 lead...
  21. ncbi request reprint The use of monitoring strategies in patients with unexplained syncope--role of the external and implantable loop recorder
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London ON, Canada
    Clin Auton Res 14:55-61. 2004
    ....
  22. ncbi request reprint Detection of asymptomatic arrhythmias in unexplained syncope
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 148:326-32. 2004
    ..We hypothesized that long-term monitoring of patients with syncope would yield significant asymptomatic abnormalities that might preclude waiting for recurrence of actual syncope...
  23. ncbi request reprint Predictive value of presyncope in patients monitored for assessment of syncope
    A D Krahn
    Division of Cardiology, University of Western Ontario, London, Canada
    Am Heart J 141:817-21. 2001
    ..The purpose of this study was to assess the diagnostic value of recording the cardiac rhythm during presyncope in patients undergoing monitoring for undiagnosed syncope...
  24. ncbi request reprint Rate-control versus conversion strategy in postoperative atrial fibrillation: a prospective, randomized pilot study
    J K Lee
    Arrhythmia Monitoring Unit, University of Western Ontario, London Health Sciences Centre, Canada
    Am Heart J 140:871-7. 2000
    ..The optimal strategy to treat the condition has not been established. Several retrospective studies have suggested that a primary rate-control strategy may be equivalent to a strategy that restores sinus rhythm...
  25. ncbi request reprint A randomized, double-blind, placebo-controlled evaluation of the efficacy and safety of intravenously administered dofetilide in patients with Wolff-Parkinson-White syndrome
    A D Krahn
    Division of Cardiology, University of Western Ontario, London, Canada
    Pacing Clin Electrophysiol 24:1258-60. 2001
    ..046). Atrial fibrillation converted to sinus rhythm in 82% of patients who received dofetilide. Intravenous dofetilide was safe and effective at converting induced atrial fibrillation in patients with WPW syndrome...
  26. ncbi request reprint Randomized assessment of syncope trial: conventional diagnostic testing versus a prolonged monitoring strategy
    A D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Circulation 104:46-51. 2001
    ..005). CONCLUSIONS: A prolonged monitoring strategy is more likely to provide a diagnosis than conventional testing in patients with unexplained syncope. Consideration should be given to earlier implementation of a monitoring strategy...
  27. ncbi request reprint Sevoflurane has no effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia
    M D Sharpe
    Department of Anaesthesia, London Health Sciences Centre, University Campus, University of Western Ontario, Canada
    Anesthesiology 90:60-5. 1999
    ....
  28. ncbi request reprint Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results
    John K Lee
    The Arrhythmia Service, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada
    Card Electrophysiol Rev 7:178-84. 2003
    ..Regardless of the strategy, majority of patients will be in sinus rhythm after two months. A larger randomized, controlled study is needed to assess the impact of restoration of sinus rhythm on length of stay...
  29. ncbi request reprint Progression to chronic atrial fibrillation after pacing: the Canadian Trial of Physiologic Pacing. CTOPP Investigators
    A C Skanes
    Division of Cardiology, University of Western Ontario, London, Canada
    J Am Coll Cardiol 38:167-72. 2001
    ..This study examined the effect of physiologic pacing on the development of chronic atrial fibrillation (CAF) in the Canadian Trial Of Physiologic Pacing (CTOPP)...
  30. ncbi request reprint Recurrent seizure diagnosed by the insertable loop recorder
    C S Simpson
    Arrhythmia Service, London Health Sciences Centre London, Ontario, Canada
    J Interv Card Electrophysiol 4:475-9. 2000
    ..The Insertable Loop Recorder (ILR) has emerged as an important new tool in the diagnostic armamentarium for patients with syncope...
  31. ncbi request reprint Use of an extended monitoring strategy in patients with problematic syncope. Reveal Investigators
    A D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Circulation 99:406-10. 1999
    ..A symptom-rhythm correlation is often difficult to obtain during spontaneous syncope because of its sporadic, infrequent, and unpredictable nature...
  32. ncbi request reprint Progressive anterior ablation in the coronary sinus region: evidence to support the presence of a 'slow pathway' input in normal patients?
    A D Krahn
    Division of Cardiology, University of Western Ontario, London, Canada
    Circulation 96:3477-83. 1997
    ..AV node modification is an emerging approach to rate control in patients with medically refractory atrial fibrillation. The mechanism of benefit of this procedure is not completely understood...
  33. doi request reprint Workup of the cardiac arrest survivor: for the symposium on sudden cardiac death for progress in cardiovascular diseases
    Rajesh Subbiah
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Prog Cardiovasc Dis 51:195-203. 2008
    ..Investigation strategies are directed at elucidating a cause or mechanism of sudden cardiac death and ultimately preventing recurrence. Detailed herein is a comprehensive approach to the assessment of a sudden cardiac death survivor...
  34. ncbi request reprint A novel mutation in KVLQT1, L122P, found in a family with autosomal dominant long QT syndrome
    A D Krahn
    Division of Cardiology and the Blackburn Cardiovascular Genetics Laboratory, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada
    Am Heart J 140:146-9. 2000
    ..Linkage and mutation analysis in long QT syndrome kindreds has demonstrated locus heterogeneity, with causative mutations reported in at least 5 different genes, including KVLQT1...
  35. ncbi request reprint Hysteresis of the RT interval with exercise: a new marker for the long-QT syndrome?
    A D Krahn
    Department of Medicine, University of Western Ontario, Canada
    Circulation 96:1551-6. 1997
    ..The diagnosis of the long-QT syndrome (LQTS) may be difficult to establish in patients with normal or borderline prolongation of the QT interval. Noninvasive markers are needed to identify patients with LQTS...
  36. ncbi request reprint Supraventricular tachycardia
    V S Chauhan
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Med Clin North Am 85:193-223, ix. 2001
    ..The mechanism and clinical manifestation of SVTs, which is essential to their correct diagnosis, is reviewed. The therapeutic management of SVTs, including acute and chronic drug therapy and catheter ablation, is discussed also...
  37. ncbi request reprint Safety and feasibility of a novel rate-smoothed ventricular pacing algorithm for atrial fibrillation
    C S Simpson
    Arrhythmia Service, Division of Cardiology, London Health Sciences Centre, London, Ontario, Canada
    Am Heart J 142:294-300. 2001
    ..The RSA may help to reduce symptoms in patients with medically refractory AF; more study is required to define its efficacy in reducing symptoms and morbidity in this population...
  38. doi request reprint Outcome of advisory implantable cardioverter-defibrillator replacement: one-year follow-up
    Paul A Gould
    University of Western Ontario, London, Ontario, Canada
    Heart Rhythm 5:1675-81. 2008
    ..There is currently a paucity of long-term data concerning the complications associated with advisory ICD replacement...
  39. ncbi request reprint Current of injury predicts acute performance of catheter-delivered active fixation pacing leads
    Damian P Redfearn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Pacing Clin Electrophysiol 30:1438-44. 2007
    ..Continuously monitoring lead parameters during fixation might better identify predictors of acute lead stability and performance...
  40. ncbi request reprint Predicting the outcome of patients with unexplained syncope undergoing prolonged monitoring
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Pacing Clin Electrophysiol 25:37-41. 2002
    ..01). The etiology of recurrent syncope is diverse and cannot be predicted by baseline clinical variables. Empiric pacing appears to have little role in the management of this patient population...
  41. ncbi request reprint Comparison of patients with syncope with left ventricular dysfunction and negative electrophysiologic testing to cardiac arrest survivors and patients with syncope and preserved left ventricular function and impact of an implantable defibrillator
    Paul Lelorier
    London Health Sciences Center, University of Western Ontario, London, Ontario, Canada
    Am J Cardiol 90:77-9. 2002
  42. ncbi request reprint Time-dependent change in fast pathway refractoriness after slow pathway ablation in atrioventricular node reentrant tachycardia. Mansfield Polaris Investigators
    A D Krahn
    Division of Cardiology, University Hospital, University of Western Ontario, London
    Can J Cardiol 13:583-8. 1997
    ..To determine the time course of change in fast pathway refractoriness after slow pathway ablation...
  43. ncbi request reprint Cryothermal ablation of the slow pathway for the elimination of atrioventricular nodal reentrant tachycardia
    A C Skanes
    Arrhythmia Services, University of Western Ontario, Montreal, Quebec, Canada
    Circulation 102:2856-60. 2000
    ..We report the first successful slow pathway ablation using a novel catheter-based cryothermal technology for the elimination of atrioventricular nodal reentrant tachycardia (AVNRT)...
  44. ncbi request reprint Recurrent unexplained syncope: diagnostic and therapeutic approach
    A D Krahn
    Department of Medicine, University of Western Ontario, London
    Can J Cardiol 12:989-94. 1996
    ..In the future, such a device may assume a prominent role in the investigation of syncope...
  45. ncbi request reprint Use of medications in Wolff-Parkinson-White syndrome
    D P Redfearn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Expert Opin Pharmacother 6:955-63. 2005
    ..An overview of the agents commonly used is provided together with recommendations...
  46. doi request reprint Defibrillation testing at the time of ICD insertion: an analysis from the Ontario ICD Registry
    J S Healey
    Population Health Research Institute and McMaster University, Hamilton, Canada
    J Cardiovasc Electrophysiol 21:1344-8. 2010
    ..increasingly, ICD implantation is performed without defibrillation testing (DT)...
  47. ncbi request reprint Correlation of waiting time with adverse events in patients admitted for nonelective permanent pacemaker implantation
    C S Simpson
    Division of Cardiology, University of Western Ontario, London
    Can J Cardiol 14:817-21. 1998
    ..To determine the effect of a dedicated permanent pacemaker implantation procedure room on waiting time and waiting time-related morbidity...
  48. ncbi request reprint Noninvasive assessment of atrial substrate change after wide area circumferential ablation: a comparison with segmental pulmonary vein isolation
    Damian P Redfearn
    Arrhythmia Service, London Health Sciences Centre, London, Ontario, Canada
    Ann Noninvasive Electrocardiol 12:329-37. 2007
    ..We examined this prospectively by comparing WACA and segmental pulmonary vein isolation (PVI) using noninvasive surrogate markers...
  49. ncbi request reprint Effect of defibrillation testing on management during implantable cardioverter-defibrillator implantation
    Peter Leong-Sit
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 152:1104-8. 2006
    ..We aimed to determine the frequency that DFT testing resulted in a change at device implant and to identify clinical and echocardiographic predictors of the need for DFT testing...
  50. doi request reprint Feasibility of magnetic resonance imaging in patients with an implantable loop recorder
    Jorge A Wong
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Pacing Clin Electrophysiol 31:333-7. 2008
    ..Our understanding of their functional and safety profile in interfering environments such as magnetic resonance imaging (MRI) becomes increasingly important as they become more prevalent...
  51. ncbi request reprint Long-term outcome of cardiac resynchronization therapy in patients with severe congestive heart failure
    Darryl R Davis
    Division of Cardiology, University of Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada
    Can J Cardiol 21:413-7. 2005
    ..Little is known about the long-term effects of this therapy...
  52. ncbi request reprint Effect of change in posture and exercise on repolarization in patients with long QT syndrome with HERG channel mutations
    Bruce D Walker
    Division of Cardiology and the Blackburn Genetics Laboratory, Roberts Research Institute, University of Western Ontario, London
    Can J Cardiol 21:33-8. 2005
    ....
  53. doi request reprint Irbesartan in patients with atrial fibrillation
    Salim Yusuf
    Population Health Research Institute, McMaster University, Hamilton, ON, Canada
    N Engl J Med 364:928-38. 2011
    ..The risk of cardiovascular events among patients with atrial fibrillation is high. We evaluated whether irbesartan, an angiotensin-receptor blocker, would reduce this risk...
  54. ncbi request reprint Images in cardiovascular medicine. Gastroesophageal reflux facilitates esophageal imaging during pulmonary vein ablation
    Lorne J Gula
    Department of Medicine, Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Circulation 114:e235-6. 2006
  55. doi request reprint Implantation of cardiac rhythm devices without interruption of oral anticoagulation compared with perioperative bridging with low-molecular weight heparin
    Alex Tischenko
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 158:252-6. 2009
    ..We assessed the safety of device implantation without interruption of warfarin therapy...
  56. doi request reprint Does familiarity with technology predict successful use of an external loop recorder? The loop recorder technology cognition study (LOCO)
    Lorne J Gula
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Pacing Clin Electrophysiol 32:466-72. 2009
    ..We prospectively assessed technological familiarity using a Technology Cognition Questionnaire to determine influence on proper and effective use of an external loop recorder (ELR)...
  57. ncbi request reprint Survival rates as a guide to implanted cardioverter-defibrillator replacement strategies for device recalls--adding statistical insight to clinical intuition
    Lorne J Gula
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Am Heart J 153:253-9. 2007
    ..The estimated risks are varied through a wide range to determine the potential range of outcomes...
  58. doi request reprint Is defibrillation testing still necessary? A decision analysis and Markov model
    Lorne J Gula
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    J Cardiovasc Electrophysiol 19:400-5. 2008
    ..To assess the impact of defibrillation threshold (DFT) testing of implanted cardioverter-defibrillators (ICDs) on survival...
  59. pmc Ejection fraction assessment and survival: an analysis of the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)
    Lorne J Gula
    University of Western Ontario, London, Ontario, Canada
    Am Heart J 156:1196-200. 2008
    ..Evidence suggests that measures of EF by different imaging modalities may not be equivalent. In the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial), the type of imaging modality for EF assessment was not mandated...
  60. doi request reprint When should we recommend catheter ablation for patients with the Wolff-Parkinson-White syndrome?
    Alexander Tischenko
    Arrhythmia Service, London Health Sciences Centre, London, Ontario, Canada
    Curr Opin Cardiol 23:32-7. 2008
    ..Its application in asymptomatic individuals with WPW pattern remains controversial. This review will elaborate on the role of catheter ablation in symptomatic and asymptomatic patients with WPW pattern on ECG...
  61. doi request reprint Impact of routine transoesophageal echocardiography on safety, outcomes, and cost of pulmonary vein ablation: inferences drawn from a decision analysis model
    Lorne J Gula
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Europace 12:1550-7. 2010
    ....
  62. ncbi request reprint Transition from narrow to wide complex tachycardia: connection or coincidence?
    Manish D Assar
    Arrhythmia Service, London Health Sciences Center, London, Ontario, Canada
    Pacing Clin Electrophysiol 26:99-100. 2003
  63. ncbi request reprint Unexpected AV block during cavotricuspid isthmus ablation
    Emoke Posan
    Division of Cardiology, Department of Medicine, University of Western Ontario, London Health Sciences Center, 339 Windermere Road, London, Ontario, Canada N6A 5A5
    Pacing Clin Electrophysiol 28:980-1. 2005
  64. ncbi request reprint Utility of a simplified lidocaine and potassium infusion in diagnosing long QT syndrome among patients with borderline QTc interval prolongation
    Vijay S Chauhan
    Division of Cardiology, University of Western Ontario, London, ON, Canada
    Ann Noninvasive Electrocardiol 9:12-8. 2004
    ..This study compared the response of the QTc interval and QT dispersion to a sequential lidocaine/K+ infusion in LQTS patients with borderline QTc interval prolongation and control patients as a means of diagnosing LQTS...
  65. ncbi request reprint Tachycardia with VA dissociation: an unusual tachycardia mechanism
    Lorne J Gula
    Department of Medicine, Division of Cardiology at London Health Sciences Centre, London, Ontario N6A 5A5, Canada
    J Cardiovasc Electrophysiol 16:663-5. 2005
  66. ncbi request reprint A wide QRS tachycardia: what is the diagnosis?
    Basilios Petrellis
    University of Western Ontario, London Health Sciences Centre, Arrhythmia Service, London, Ontario, Canada N6A 5A5
    J Cardiovasc Electrophysiol 15:501-3. 2004
  67. ncbi request reprint Hybrid approach for minimally-invasive operative therapy of arrhythmias
    Allan C Skanes
    Arrhythmia Service, Division of Cardiology, University of Western Ontario, London Health Sciences Centre, University Campus, 339 Windermere Road, London, Ontario, Canada N6A 5A5
    J Interv Card Electrophysiol 9:289-94. 2003
    ..This step will be crucial in understanding why specific procedures ultimately fail to cure AF and other complex arrhythmias...
  68. ncbi request reprint Cryoablation of atrial arrhythmias
    Allan C Skanes
    Arrhythmia Service, University of Western Ontario, London, Ontario, Canada
    Card Electrophysiol Rev 6:383-8. 2002
    ..The ultimate role of catheter-based cryoablation remains to be determined. A number of promising aspects of this ablation energy make it an exciting technology...
  69. ncbi request reprint Syncope and polymorphic ventricular tachycardia
    Bruce D Walker
    Arrhythmia Service, London Health Sciences Center, Ontario, Canada
    Pacing Clin Electrophysiol 25:1259-61. 2002
  70. ncbi request reprint Beta blockers normalize QT hysteresis in long QT syndrome
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 143:528-34. 2002
    ..This study was performed to evaluate the impact of beta blockers on QT adaptation to heart rate during the exercise and recovery phases of exercise testing in long QT syndrome...
  71. ncbi request reprint Primary prophylaxis of sudden death in hypertrophic cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, and dilated cardiomyopathy
    George J Klein
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    J Cardiovasc Electrophysiol 16:S28-34. 2005
    ..A rational approach to these therapies, with emphasis on implanted cardiovertor defibrillators, is discussed...
  72. ncbi request reprint Laser lead extraction: is there a learning curve?
    Nina Ghosh
    Division of Cardiology and Cardiac Surgery, University of Western Ontario, London, Ontario, Canada
    Pacing Clin Electrophysiol 28:180-4. 2005
    ....
  73. doi request reprint Predicting the cause of syncope from clinical history in patients undergoing prolonged monitoring
    Sachin Sud
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Heart Rhythm 6:238-43. 2009
    ..Although these correlate with morbidity and mortality in patients with syncope, their relationship with the mechanism of syncope has not been investigated...
  74. ncbi request reprint Pacing for vasovagal syncope after the second Vasovagal Pacemaker Study (VPS II): a matter of judgement
    Geoffrey M Trim
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Card Electrophysiol Rev 7:416-20. 2003
    ..More needs to be learned about optimal pacing modalities...
  75. doi request reprint Reduction of complex ventricular ectopy and improvement in exercise capacity with flecainide therapy in Andersen-Tawil syndrome
    David J Fox
    Department of Medicine, Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Europace 10:1006-8. 2008
    ....
  76. doi request reprint Evaluation of early complications related to De Novo cardioverter defibrillator implantation insights from the Ontario ICD database
    Douglas S Lee
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Toronto General Hospital, Toronto, Ontario, Canada
    J Am Coll Cardiol 55:774-82. 2010
    ..This study examined the predictors of early complications after defibrillator implantation...
  77. pmc Torsades de pointes during complete atrioventricular block: Genetic factors and electrocardiogram correlates
    Rajesh N Subbiah
    University of Western Ontario, London
    Can J Cardiol 26:208-12. 2010
    ..It was hypothesized that patients with AV block-mediated QT-related arrhythmia may have latent congenital long QT syndrome or a vulnerable genetic polymorphism...
  78. ncbi request reprint Optimal duration of monitoring in patients with unexplained syncope
    Manish D Assar
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am J Cardiol 92:1231-3. 2003
    ..Syncope is most likely to occur in younger patients with less heart disease and more frequent syncope. There is a low risk of syncope after 1 year of monitoring without an event...
  79. doi request reprint Utility of treadmill testing in identification and genotype prediction in long-QT syndrome
    Jorge A Wong
    Arrhythmia Service, Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Circ Arrhythm Electrophysiol 3:120-5. 2010
    ..We sought to develop a provocative testing strategy to unmask the LQTS phenotype and relate this to the results of genetic testing...
  80. pmc Arrhythmia device lead extraction: factors that necessitate laser assistance
    Lorne J Gula
    Department of Medicine, University of Western Ontario, London, Canada
    Can J Cardiol 24:767-70. 2008
    ..It is not an option at all centres and introduces an element of risk to the procedure. Anticipation of the need for laser assistance may be of benefit to procedure planning...
  81. ncbi request reprint The garden path
    Paul A Gould
    Department of Medicine, Division of Cardiology, University of Western Ontario, London, Ontario N6A 5A5, Canada
    J Cardiovasc Electrophysiol 17:440-2. 2006
  82. ncbi request reprint Isolation of pulmonary veins using a transvenous curvilinear cryoablation catheter: feasibility, initial experience, and analysis of recurrences
    Allan C Skanes
    Arrhythmia Service, London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada
    J Cardiovasc Electrophysiol 16:1304-8. 2005
    ..We hypothesized that a linear freezing segment could shorten fluoroscopic and procedure times. We report our initial experience with a novel circular cryothermal catheter...
  83. ncbi request reprint Sudden cardiac death despite an implantable cardioverter-defibrillator in a young female with catecholaminergic ventricular tachycardia
    Uwais Mohamed
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Heart Rhythm 3:1486-9. 2006
  84. ncbi request reprint Implications of mechanism of bradycardia on response to pacing in patients with unexplained syncope
    Sachin Sud
    Division of Cardiology, University of Western Ontario, London Health Sciences Centre, University Campus, C6 113 339 Windermere road, London, Ontario N6A 5A5, Canada
    Europace 9:312-8. 2007
    ....
  85. ncbi request reprint Differentiating arrhythmogenic right ventricular cardiomyopathy from right ventricular outflow tract ventricular tachycardia using multilead QRS duration and axis
    Craig D Ainsworth
    Division of Cardiology, University of Western Ontario, London, Canada
    Heart Rhythm 3:416-23. 2006
    ..Ventricular tachycardia (VT) resulting from arrhythmogenic right ventricular cardiomyopathy (ARVC) may be difficult to differentiate from idiopathic right ventricular outflow tract (RVOT) VT...
  86. ncbi request reprint Atrial response to ventricular antitachycardia pacing discriminates mechanism of 1:1 atrioventricular tachycardia
    Daryl P Ridley
    London Health Sciences Centre, London, Ontario N6A 5A5, Canada
    J Cardiovasc Electrophysiol 16:601-5. 2005
    ..The atrial response to antitachycardia pacing (ATP) may determine the mechanism of 1:1 A:V tachycardia...
  87. doi request reprint Differential ventricular entrainment: a maneuver to differentiate AV node reentrant tachycardia from orthodromic reciprocating tachycardia
    Oliver R Segal
    Division of Cardiology, University Hospital, London Health Sciences Centre, London, Ontario, Canada
    Heart Rhythm 6:493-500. 2009
    ..A pacing maneuver that reliably distinguishes between the two would be of value...
  88. ncbi request reprint Complications associated with implantable cardioverter-defibrillator replacement in response to device advisories
    Paul A Gould
    Division of Cardiology, Department of Medicine, University of Western Ontario, London
    JAMA 295:1907-11. 2006
    ..The risk of ICD generator replacement has not been assessed in this population...
  89. ncbi request reprint Esophageal temperature monitoring during radiofrequency ablation of atrial fibrillation
    Damian P Redfearn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    J Cardiovasc Electrophysiol 16:589-93. 2005
    ..Unfortunately, ablation in the posterior left atrium has been reported to result in fatal atrio-esophageal fistula...
  90. ncbi request reprint An unusual accessory pathway: anteroseptal to ventricular outflow region connection
    Basilios Petrellis
    University of Western Ontario, Arrhythmia Service, London, Ontario, Canada
    J Cardiovasc Electrophysiol 16:546-51. 2005
    ..This is the second such pathway observed at our institution over a 20-year period...
  91. pmc Formation of a national network for rapid response to device and lead advisories: The Canadian Heart Rhythm Society Device Advisory Committee
    A D Krahn
    London Health Sciences Centre, London, Canada
    Can J Cardiol 25:403-5. 2009
    ..The network is an ideal tool to collect specific data on implanted device system performance and allows for prompt reporting of clinically relevant data to front-line clinicians and patients...
  92. pmc Clinical relevance of arrhythmias during sleep: guidance for clinicians
    L J Gula
    Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Heart 90:347-52. 2004
  93. ncbi request reprint Asymptomatic Wolff-Parkinson-White syndrome: is it time to revisit guidelines?
    Derick M Todd
    J Am Coll Cardiol 41:245-8. 2003
  94. ncbi request reprint A classic but uncommon principle
    Emoke Posan
    Department of Medicine, Division of Cardiology at London Health Science Centre, London, Ontario, Canada
    J Cardiovasc Electrophysiol 17:106-7. 2006
  95. ncbi request reprint A sheep in wolf's clothing?
    Oliver R Segal
    Department of Medicine, Division of Cardiology at London Health Science Centre, London, Canada
    J Cardiovasc Electrophysiol 18:1338-9. 2007
  96. ncbi request reprint Worsening of symptoms before presentation with vasovagal syncope
    Robert S Sheldon
    Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Canada
    J Cardiovasc Electrophysiol 18:954-9. 2007
    ..Much of the natural history of vasovagal syncope is unknown. We determined whether patients presenting for care have had a recently worsened syncope frequency...
  97. ncbi request reprint Is ambulatory monitoring for "community-acquired" syncope economically attractive? A cost-effectiveness analysis of a randomized trial of external loop recorders versus Holter monitoring
    Marie Antoinette Rockx
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Am Heart J 150:1065. 2005
    ..The cost-effectiveness of 2 monitoring strategies was assessed in a prospective randomized trial...
  98. ncbi request reprint Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study
    Scott D Corley
    Axio Research Corporation, Seattle, Wash, USA
    Circulation 109:1509-13. 2004
    ..This article reports an "on-treatment" analysis of the relationship of survival to cardiac rhythm and treatment as they changed over time...
  99. ncbi request reprint Take heart: gone but not forgotten?
    David J Fox
    Division of Cardiology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    J Cardiovasc Electrophysiol 19:438-9. 2008
  100. ncbi request reprint Pacemakers and portable media players: harm or harmony?
    Andrew D Krahn
    Heart Rhythm 5:551-2. 2008
  101. ncbi request reprint External loop recorders: determinants of diagnostic yield in patients with syncope
    Lorne J Gula
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 147:644-8. 2004
    ..The purpose of the current study was to determine the optimal duration of external loop recorder (ELR) monitoring in patients with presyncope or syncope and to identify factors that predict failure to activate the device effectively...