Research Topics
| Anita KozyrskyjSummaryAffiliation: University of Manitoba Country: Canada Publications
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Detail Information
Publications
Antibiotic treatment of wheezing in children with asthma: what is the practice?Anita L Kozyrskyj
Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
Pediatrics 117:e1104-10. 2006..This study was undertaken to evaluate trends and determinants of antibiotic use in children with wheezing during the fiscal years 1995 through 2001...
Increased risk of childhood asthma from antibiotic use in early lifeAnita L Kozyrskyj
Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, Canada R3T 2N2
Chest 131:1753-9. 2007....
Income-based drug benefit policy: impact on receipt of inhaled corticosteroid prescriptions by Manitoba children with asthmaA L Kozyrskyj
Department of Community Health Sciences, Manitoba Centre for Health Policy and Evaluation, Faculty of Medicine, University of Manitoba, Winnipeg, Man
CMAJ 165:897-902. 2001....
Continued exposure to maternal distress in early life is associated with an increased risk of childhood asthmaAnita L Kozyrskyj
Faculty of Pharmacy, Department of Community Health Sciences, Manitoba Centre for Health Policy, University of Manitoba, Winnipeg, Manitoba, Canada
Am J Respir Crit Care Med 177:142-7. 2008..Evidence is emerging that exposure to maternal distress in early life plays a causal role in the development of childhood asthma...
Characterizing early prescribers of newly marketed drugs in Canada: a population-based studyAnita Kozyrskyj
Faculty of Pharmacy and Medicine, Department of Community Health Sciences and Pediatrics and Child Health, Manitoba Centre for Health Policy, University of Manitoba, 210 Pharmacy Bldg, Winnipeg, MB, Canada
Eur J Clin Pharmacol 63:597-604. 2007..This study was undertaken to determine if early prescribers and users of newly marketed drugs had different sociodemographic and professional characteristics as compared to majority and late users and prescribers...
Use of celecoxib immediately post marketing in Canada: acute or chronic pain?Anita L Kozyrskyj
Faculty of Pharmacy, University of Manitoba, Canada
Can J Clin Pharmacol 14:e70-80. 2007....
Evidence-based prescribing of antibiotics for children: role of socioeconomic status and physician characteristicsAnita L Kozyrskyj
Department of Community Health Sciences, Manitoba Centre for Health Policy, University of Manitoba, Winnipeg
CMAJ 171:139-45. 2004..This study was undertaken to determine child, household and physician factors predictive of nonadherence to evidence-based antibiotic prescribing in children...
Decrease in antibiotic use among children in the 1990s: not all antibiotics, not all childrenAnita L Kozyrskyj
Department of Community Health Sciences, Manitoba Centre for Health Policy, University of Manitoba, Winnipeg
CMAJ 171:133-8. 2004..This study was undertaken to determine trends in the use of antibiotics from fiscal year (FY) 1995 (April 1995 to March 1996) to FY 2001 in a complete population of Manitoba children...
Identifying children with persistent asthma from health care administrative recordsAnita L Kozyrskyj
Department of Community Health Sciences, Manitoba Centre for Health Policy, University of Manitoba, Winnipeg
Can Respir J 11:141-5. 2004..Investigation into the origins of asthma is contingent on definitions of asthma, which can differentiate asthma from transient wheezing syndromes in children...
Socioeconomic status, drug insurance benefits, and new prescriptions for inhaled corticosteroids in schoolchildren with asthmaA L Kozyrskyj
Department of Community Health Sciences, Manitoba Centre for Health Policy and Evaluation, Faculty of Medicine, University of Manitoba, S101 750 Bannatyne Ave, Winnipeg, Manitoba R3E 0W3, Canada
Arch Pediatr Adolesc Med 155:1219-24. 2001..Low-income children with asthma are less likely to receive inhaled corticosteroid prescriptions that can prevent asthma morbidity...
Childhood wheezing syndromes and healthcare dataAnita L Kozyrskyj
Department of Community Health Sciences, Manitoba Centre for Health Policy, University of Manitoba, Winnipeg, Manitoba, Canada
Pediatr Pulmonol 36:131-6. 2003..Healthcare administrative records can be used to describe the natural history of wheezing in children and to identify markers which may discriminate asthma from other syndromes...
Assessing health status in Manitoba children: acute and chronic conditionsAnita L Kozyrskyj
Manitoba Centre for Health Policy, Department of Community Health Sciences, Faculty of Medicine, University of Manitoba, Winnipeg, MB
Can J Public Health 93:S44-9. 2002..CONCLUSION: A minority of Manitoba children suffer from chronic and serious acute health problems in childhood, but the burden of illness is not evenly distributed among children...
The virtual classroom: a summary of child health indicatorsPatricia J Martens
Manitoba Centre for Health Policy, Department of Community Health Sciences, Faculty of Medicine, University of Manitoba, Winnipeg, MB
Can J Public Health 93:S77-80. 2002....
Inhaled corticosteroids in childhood asthma: Income differences in useAnita L Kozyrskyj
Department of Community Health Sciences, Manitoba Centre for Health Policy, Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
Pediatr Pulmonol 36:241-7. 2003..In conclusion, a socioeconomic gradient in the use of inhaled corticosteroids prescriptions can be found among children with universal access to healthcare and drug insurance...
Transient tachypnea of the newborn may be an early clinical manifestation of wheezing symptomsJoel J Liem
Section of Allergy and Clinical Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada
J Pediatr 151:29-33. 2007..To determine risk factors associated with transient tachypnea of the newborn (TTN) and whether TTN is associated with development of wheezing syndromes in early life...
Utilization and costs of antipsychotic agents: a Canadian population-based study, 1996-2006Silvia Alessi-Severini
Faculty of Pharmacy, University of Manitoba, Fort Garry Campus, Winnipeg, Manitoba, Canada
Psychiatr Serv 59:547-53. 2008..This study evaluated the prescribing patterns and costs for antipsychotic agents in the population of the Canadian province of Manitoba over the past decade...
Prescription medications in Manitoba children: are there regional differences?Anita L Kozyrskyj
Manitoba Centre for Health Policy, Department of Community Health Sciences, Faculty of Medicine, University of Manitoba, Winnipeg, MB
Can J Public Health 93:S63-9. 2002..We undertook an evaluation of regional differences in prescription drug use by Manitoba children...
Lower cortisol levels in children with asthma exposed to recurrent maternal distress from birthLisa C Dreger
Department of Psychology, University of Manitoba, Winnipeg, Manitoba, Canada
J Allergy Clin Immunol 125:116-22. 2010....
Community resources and determinants of the future health of ManitobansAnita L Kozyrskyj
Manitoba Centre for Health Policy, Department of Community Health Sciences, Faculty of Medicine, University of Manitoba, Winnipeg, MB
Can J Public Health 93:S70-6. 2002..The objectives of this research were to describe the regional distribution of childhood determinants of adult health, such as school achievement, and the environments which contribute to their development...
Development of a drug treatment-based severity measure in childhood asthmaAnita L Kozyrskyj
Department of Community Health Sciences, Manitoba Centre for Health Policy, Faculty of Medicine, Winnipeg, Canada
J Asthma 39:421-8. 2002..These findings show that a drug treatment-based severity measure in childhood asthma, which can be applied to prescription data, has good reliability and validity, and is responsive to changes in asthma severity over time...
Diagnosing asthma in children: what is the role for methacholine bronchoprovocation testing?Joel J Liem
Section of Allergy and Clinical Immunology, Department of Pediatrics and Child Health, Manitoba Institute of Child Health, University of Manitoba, Manitoba, Canada
Pediatr Pulmonol 43:481-9. 2008..To determine whether measurement of airways responsiveness to methacholine can help physicians diagnose asthma in children...
Using a population-based health information system to study child healthMarni Brownell
Manitoba Centre for Health Policy, Department of Community Health Sciences, Faculty of Medicine, University of Manitoba, Winnipeg, MB
Can J Public Health 93:S9-14. 2002..This paper describes the population-based analyses of measures of child health status used throughout this supplement...
Trends in psychostimulant and antidepressant use by children in 2 Canadian provincesBrendon Mitchell
Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba
Can J Psychiatry 53:152-9. 2008..We used population-based administrative prescription medication data to examine regional differences in psychostimulant and antidepressant (AD) use among children from 2 Canadian provinces: British Columbia (BC) and Manitoba (MB)...
Effect of regulatory warnings on antidepressant prescription rates, use of health services and outcomes among children, adolescents and young adultsLaurence Y Katz
Department of Psychiatry, University of Manitoba, Winnipeg, Man
CMAJ 178:1005-11. 2008..We sought to determine whether the Health Canada warning had the desired effects on prescribing patterns and outcomes and whether it had any unintended health consequences...
The burden of seizures in Manitoba children: a population-based studyAnita L Kozyrskyj
Manitoba Centre for Health Policy, Winnipeg, MB Canada
Can J Neurol Sci 31:48-52. 2004..CONCLUSIONS: Population-based health care administrative data can be used to describe the geographical distribution of seizure disorders. Our data suggest that the burden of seizure disorders is not evenly distributed among children...
Asthma is not enough: continuation of smoking among parents with an asthmatic childJoel J Liem
Section of Allergy and Clinical Immunology, Department of Pediatrics and Child Health, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba
Can Respir J 14:349-53. 2007..Ideally, on diagnosis of asthma in a child, parents are counselled to decrease environmental tobacco smoke exposure to their children...
The relationship of breast-feeding, overweight, and asthma in preadolescentsXiao Mei Mai
Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
J Allergy Clin Immunol 120:551-6. 2007..Breast-feeding is suggested to be associated with overweight or asthma in children. Overweight and asthma may share common environmental influences of which breast-feeding may be one...
Epigenetic regulation of established human type 1 versus type 2 cytokine responsesRuey Chyi Su
Canadian Institute for Health Research, National Training Program in Allergy and Asthma Research, Department of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada
J Allergy Clin Immunol 121:57-63.e3. 2008..Multiple biologic factors influence maintenance of immunologic responsiveness. Here, we studied whether epigenetics has a regulatory function in maintaining pre-established T(H)1-like and T(H)2-like immunity in human beings...
Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthmaKara L McDonald
Faculty of Medicine, Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
J Allergy Clin Immunol 121:626-31. 2008..Early childhood immunizations have been viewed as promoters of asthma development by stimulating a T(H)2-type immune response or decreasing microbial pressure, which shifts the balance between T(H)1 and T(H)2 immunity...
Normalization strategies of children with asthmaJennifer L P Protudjer
Department of Applied Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
Qual Health Res 19:94-104. 2009..These findings suggest that aspects of other researchers' work regarding normalization efforts of children with various chronic diseases also apply in a chronic condition that is less obvious...
A population-based analysis of statin utilization in British ColumbiaColette B Raymond
University of Manitoba, Faculty of Pharmacy, Department of Pharmaceutical Services Health Sciences Centre, Winnipeg, Manitoba, Canada
Clin Ther 29:2107-19. 2007..The purpose of this research was to measure prevalent and incident statin use in the population of British Columbia from 1996 to 2004 across specific patient characteristics (sociodemographic and clinical)...
The risk of developing food allergy in premature or low-birth-weight childrenJoel J Liem
Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada
J Allergy Clin Immunol 119:1203-9. 2007..Premature or low-birth-weight children have increased gut permeability compared with term or normal-birth-weight children...
TLR4 Asp299Gly and Thr399Ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virusRenée N Douville
CIHR National Training Program in Allergy and Asthma Research, Department of Immunology, University of Manitoba, Winnipeg, Canada
PLoS ONE 5:e12087. 2010..Here we determine the importance of these polymorphisms in modulating LPS and respiratory syncytial virus (RSV)--driven cytokine responses. We focus on both healthy children and those with clinically relevant respiratory dysfunction...
Disease, temporal and sociodemographic influences on initial treatment of community-acquired pneumonia in Manitoba, CanadaAnita G Carrie
Faculty of Pharmacy and Pharmaceutical Sciences, 3118 Dentistry Pharmacy Building, University of Alberta, Edmonton, Alberta, Canada T6G 2N8
Int J Antimicrob Agents 28:95-100. 2006..87). Among outpatients, restricted antibiotics were widely received and differences in use by income were modest...
Outpatient treatment of community-acquired pneumonia: evolving trends and a focus on fluoroquinolonesAnita G Carrie
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta
Can J Clin Pharmacol 13:e102-11. 2006..Community-acquired pneumonia (CAP) is commonly treated on an outpatient basis, and recent treatment guidelines suggest only a limited role for fluoroquinolones...
Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissuesKarine Tremblay
Hopital Laval, Universite Laval, Quebec, Canada
J Allergy Clin Immunol 122:529-36.e17. 2008..Eight genes in the immune signaling pathway shown to be differentially expressed in asthmatic lung biopsy specimens in a previous microarray experiment were selected as candidate genes for asthma susceptibility...
Association of urokinase-type plasminogen activator with asthma and atopyPhilippe Bégin
University of Montreal Community Genomic Medicine Centre, Chicoutimi University Hospital, Saguenay, Quebec, Canada
Am J Respir Crit Care Med 175:1109-16. 2007..This region has demonstrated evidence for linkage in a genome scan for asthma in a sample from northeastern Quebec. Here, we hypothesized that uPA may function as a regulator of asthma susceptibility...
