Affiliation: University of Ottawa
- Parental bonds in children at high and low familial risk for panic disorderDiana Koszycki
Faculty of Education, University of Ottawa, 145 Jean Jacques Lussier, Ottawa, ON, K1N 6N5, Canada
Child Psychiatry Hum Dev 44:278-89. 2013..05). Overall, these data suggest that parental PD does not compromise the parent-child bonds in never-ill offspring...
- CCK-B receptor gene and response to cholecystokinin-tetrapeptide in healthy volunteersDiana Koszycki
Department of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada
Peptides 35:9-13. 2012..The significant association between the risk alleles and anxiety-related personality traits is intriguing and further exploration of this association is merited...
- Interpersonal psychotherapy versus brief supportive therapy for depressed infertile women: first pilot randomized controlled trialDiana Koszycki
Faculty of Education, University of Ottawa, 145 Jean Jacques Lussier, Ottawa, Ontario, Canada
Arch Womens Ment Health 15:193-201. 2012..Should subsequent randomized controlled trials support these findings, this will inform clinical practice and take an important step in assuring optimal care for depressed women struggling with infertility...
- A randomized trial of sertraline, self-administered cognitive behavior therapy, and their combination for panic disorderD Koszycki
Faculty of Education, University of Ottawa, ON, Canada
Psychol Med 41:373-83. 2011..However, it is unknown whether combining SCBT and antidepressants can improve treatment. This trial evaluated the efficacy of SCBT and sertraline, alone or in combination, in PD...
- A multifaith spiritually based intervention for generalized anxiety disorder: a pilot randomized trialDiana Koszycki
Faculty of Education, University of Ottawa, Ontario, Canada
J Clin Psychol 66:430-41. 2010..These preliminary findings are encouraging and suggest that a multifaith SBI may be an effective treatment option for GAD. Further randomized controlled trials are needed to establish the efficacy of this intervention...
- Effects of CCK-4 infusion on the acoustic eye-blink startle and psychophysiological measures in healthy volunteersJ Shlik
Royal Ottawa Hospital, University of Ottawa, Ontario, Canada
J Psychopharmacol 13:385-90. 1999..The results of this study show that a prolonged intravenous administration of CCK-4 may be a useful challenge method for further studies on the role of CCK system in the modulation of human anxiety and stress response...
- Behavioral, cardiovascular, and neuroendocrine profiles following CCK-4 challenge in healthy volunteers: a comparison of panickers and nonpanickersD Koszycki
Stress and Anxiety Clinical Research Unit, Royal Ottawa Hospital, Ontario, Canada
Depress Anxiety 8:1-7. 1998....
- Effect of aging on cholecystokinin-induced panicA J Flint
Department of Psychiatry, University of Toronto, Quebec, Canada
Am J Psychiatry 155:283-5. 1998..The goal of this study was to determine whether aging has an effect on healthy subjects' responses to the panicogenic agent cholecystokinin tetrapeptide (CCK-4)...
- Investigation of cholecystokinin system genes in panic disorderJ L Kennedy
Clarke Division, Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada
Mol Psychiatry 4:284-5. 1999..Our genetic dissection of the CCK system thus far suggests that the CCK-B receptor gene variation may contribute to the neurobiology of panic disorder...
- Neurohormonal responses to cholecystokinin tetrapeptide: a comparison of younger and older healthy subjectsA J Flint
The Department of Psychiatry, University of Toronto, Ontario, Canada
Psychoneuroendocrinology 25:633-47. 2000..For the most part, maximum changes in hormonal levels were not correlated with symptom severity, suggesting that other factors may have contributed to the differential effect of panic on the HPA axis...
- Arginine-vasopressin and oxytocin response to cholecystokinin-tetrapeptideJ M Le Melledo
Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
Peptides 22:1349-57. 2001..AVP and OT may play a role in the hypothalamo-pituitary adrenal (HPA) axis activity associated with the panic response induced by CCK-4...
- Decrease in short-term memory function induced by CCK-4 in healthy volunteersJ Shlik
Stress and Anxiety Clinical Research Unit, Royal Ottawa Hospital, University of Ottawa, Ontario, Canada
Peptides 19:969-75. 1998..The results of this study indicate that CCK-4 may exert a negative influence on memory consolidation and retrieval...
- Behavioral, neurochemical, anatomical and electrophysiological correlates of panic disorder: multiple transmitter interaction and neuropeptide colocalizationR M Zacharko
Psychology Department, Carleton University, Ottawa, Ontario, Canada
Prog Neurobiol 47:371-423. 1995..Such variables presumably underlie the diverse behavioral symptoms associated with panic disorder and variations in the therapeutic efficacy of pharmacological treatment...
- Association study of serotonin-2A receptor gene polymorphism and panic disorder in patients from Canada and GermanyC Rothe
Department of Psychiatry, University of Ottawa and the University of Ottawa Institute of Mental Health Research, Royal Ottawa Hospital, Ottawa, Canada
Neurosci Lett 363:276-9. 2004..Our data suggest thus that this polymorphism is unlikely to play a major role in the pathogenesis of panic disorder...
- A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjectsJ Bradwejn
Royal Ottawa Hospital and the Department of Psychiatry, University of Ottawa, Ontario, Canada
J Clin Psychopharmacol 20:680-4. 2000..These preliminary findings suggest that Gotu Kola has anxiolytic activity in humans as revealed by the ASR. It remains to be seen whether this herb has therapeutic efficacy in the treatment of anxiety syndromes...
- Anxiety sensitivity does not predict fearful responding to 35% carbon dioxide in patients with panic disorderD Koszycki
Stress and Anxiety Clinical Research Unit, Royal Ottawa Hospital, 1145 Carling Avenue, K1Z 7K4, Ottawa, Canada
Psychiatry Res 101:137-43. 2001..Overall, these data do not support the view that anxiety sensitivity plays a key role in mediating behavioural sensitivity to CO(2) inhalation in panic disorder...
- Cholecystokinin and panic disorder: past and future clinical research strategiesJ Bradwejn
Department of Psychiatry, University of Ottawa and the Royal Ottawa Hospital, Ontario, Canada
Scand J Clin Lab Invest Suppl 234:19-27. 2001....
- Prenatal social support, postnatal social support, and postpartum depressionRi Hua Xie
OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada
Ann Epidemiol 19:637-43. 2009..To assess the association of antenatal and postnatal social support with postpartum depression (PPD)...