Linda M Kohn

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Mechanisms of fungal speciation
    Linda M Kohn
    Department of Botany, University of Toronto, Mississauga, Ontario, Canada L5L 1C6
    Annu Rev Phytopathol 43:279-308. 2005
  2. pmc Population genomics of drug resistance in Candida albicans
    Leah E Cowen
    Department of Botany, University of Toronto, Mississauga, ON, Canada L5L 1C6
    Proc Natl Acad Sci U S A 99:9284-9. 2002
  3. pmc Single nucleotide polymorphism-based diagnostic system for crop-associated Sclerotinia species
    Marion Andrew
    Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario L5L 1C6, Canada
    Appl Environ Microbiol 75:5600-6. 2009
  4. pmc Divergent adaptation promotes reproductive isolation among experimental populations of the filamentous fungus Neurospora
    Jeremy R Dettman
    Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, ON, L5L 1C6, Canada
    BMC Evol Biol 8:35. 2008
  5. ncbi request reprint Marker stability throughout 400 days of in vitro hyphal growth in the filamentous ascomycete, Sclerotinia sclerotiorum
    Linda M Kohn
    Department of Ecology and Evolutionary Biology, University of Toronto, 3359 Mississauga Road North, Mississauga, ON, Canada
    Fungal Genet Biol 45:613-7. 2008
  6. pmc Host-synthesized secondary compounds influence the in vitro interactions between fungal endophytes of maize
    Megan Saunders
    Department of Ecology and Evolutionary Biology, University of Toronto, 3359 Mississauga Road North, Mississauga, Ontario, Canada
    Appl Environ Microbiol 74:136-42. 2008
  7. ncbi request reprint Incipient speciation by divergent adaptation and antagonistic epistasis in yeast
    Jeremy R Dettman
    Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario, L5L 1C6, Canada
    Nature 447:585-8. 2007
  8. ncbi request reprint Evolution of drug resistance in Candida albicans
    Leah E Cowen
    Department of Botany, University of Toronto, Mississauga, Ontario, L5L 1C6, Canada
    Annu Rev Microbiol 56:139-65. 2002
  9. pmc Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae
    James B Anderson
    Department of Botany, University of Toronto, Mississauga, Ontario L5L 1C6, Canada
    Genetics 163:1287-98. 2003
  10. pmc Origins of host-specific populations of the blast pathogen Magnaporthe oryzae in crop domestication with subsequent expansion of pandemic clones on rice and weeds of rice
    Brett C Couch
    Department of Botany, University of Toronto, Mississauga, Ontario, Canada
    Genetics 170:613-30. 2005

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Mechanisms of fungal speciation
    Linda M Kohn
    Department of Botany, University of Toronto, Mississauga, Ontario, Canada L5L 1C6
    Annu Rev Phytopathol 43:279-308. 2005
    ....
  2. pmc Population genomics of drug resistance in Candida albicans
    Leah E Cowen
    Department of Botany, University of Toronto, Mississauga, ON, Canada L5L 1C6
    Proc Natl Acad Sci U S A 99:9284-9. 2002
    ..The three patterns of gene expression were also identified in fluconazole-resistant clinical isolates, providing further evidence that these patterns represent common programs of adaptation to fluconazole...
  3. pmc Single nucleotide polymorphism-based diagnostic system for crop-associated Sclerotinia species
    Marion Andrew
    Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario L5L 1C6, Canada
    Appl Environ Microbiol 75:5600-6. 2009
    ..The SNP-based assay accurately identified 96% of Sclerotinia isolates and could be performed faster than RFLP profiling using pMF2. This method shows promise for accurate, high-throughput species identification...
  4. pmc Divergent adaptation promotes reproductive isolation among experimental populations of the filamentous fungus Neurospora
    Jeremy R Dettman
    Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, ON, L5L 1C6, Canada
    BMC Evol Biol 8:35. 2008
    ..We then measured the influence that initial genetic diversity and the direction of selection (parallel versus divergent) had on the evolution of reproductive isolation...
  5. ncbi request reprint Marker stability throughout 400 days of in vitro hyphal growth in the filamentous ascomycete, Sclerotinia sclerotiorum
    Linda M Kohn
    Department of Ecology and Evolutionary Biology, University of Toronto, 3359 Mississauga Road North, Mississauga, ON, Canada
    Fungal Genet Biol 45:613-7. 2008
    ..This observation has implications for modeling pathogen tolerance or adaptation under conditions of environmental stochasticity, including climate warming...
  6. pmc Host-synthesized secondary compounds influence the in vitro interactions between fungal endophytes of maize
    Megan Saunders
    Department of Ecology and Evolutionary Biology, University of Toronto, 3359 Mississauga Road North, Mississauga, Ontario, Canada
    Appl Environ Microbiol 74:136-42. 2008
    ..The hypothesis drawn from these data is that in the presence of a toxin, fungal species that detoxify their substrate can enhance the colonization rate of less tolerant fungi...
  7. ncbi request reprint Incipient speciation by divergent adaptation and antagonistic epistasis in yeast
    Jeremy R Dettman
    Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario, L5L 1C6, Canada
    Nature 447:585-8. 2007
    ....
  8. ncbi request reprint Evolution of drug resistance in Candida albicans
    Leah E Cowen
    Department of Botany, University of Toronto, Mississauga, Ontario, L5L 1C6, Canada
    Annu Rev Microbiol 56:139-65. 2002
    ..Predicting the evolution of drug resistance is fundamental to prolonging the efficacy of existing drugs and to strategically developing and deploying novel drugs...
  9. pmc Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae
    James B Anderson
    Department of Botany, University of Toronto, Mississauga, Ontario L5L 1C6, Canada
    Genetics 163:1287-98. 2003
    ..In a variation of experiment 2, haploids showed a higher frequency of resistance than diploids, suggesting that degree of dominance and ploidy are important factors in the evolution of antifungal drug resistance...
  10. pmc Origins of host-specific populations of the blast pathogen Magnaporthe oryzae in crop domestication with subsequent expansion of pandemic clones on rice and weeds of rice
    Brett C Couch
    Department of Botany, University of Toronto, Mississauga, Ontario, Canada
    Genetics 170:613-30. 2005
    ..There is evidence of a common origin of both ACE1 virulence genotypes in haplotype 14. Host-haplotype association is evidenced by low pathogenicity on hosts associated with other haplotypes...
  11. pmc Evidence for a common toolbox based on necrotrophy in a fungal lineage spanning necrotrophs, biotrophs, endophytes, host generalists and specialists
    Marion Andrew
    Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario, Canada
    PLoS ONE 7:e29943. 2012
    ..Early oah overexpression likely expands the host range of necrotrophic generalists in the Sclerotiniaceae, while specialists and biotrophs deploy oah, or other as-yet-unknown toolbox genes, differently...
  12. doi request reprint Genome-wide investigation of reproductive isolation in experimental lineages and natural species of Neurospora: identifying candidate regions by microarray-based genotyping and mapping
    Jeremy R Dettman
    Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario, L5L 1C6, Canada
    Evolution 64:694-709. 2010
    ..This study demonstrates how advances in high-throughput, genome-wide genotyping can be applied to mapping reproductive isolation genes and speciation research...
  13. pmc Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populations
    James B Anderson
    Centre for the Analysis of Genome Function, Department of Cell and Systems Biology, and Department of Ecology and Evolutionary Biology, University of Toronto, Mississauga, Ontario, Canada
    Curr Biol 20:1383-8. 2010
    ..This DM interaction is the first reported between experimentally evolved alleles of known genes and shows how reproductive isolation can arise rapidly when divergent selection is strong...
  14. ncbi request reprint An optimized method for mycelial compatibility testing in Sclerotinia sclerotiorum
    Michelle R Schafer
    Biology Department, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada
    Mycologia 98:593-7. 2006
    ..Workers are advised to optimize conditions before screening a new population sample...