F S Kibenge


Affiliation: University of Prince Edward Island
Country: Canada


  1. Kibenge M, Wang Y, Gayeski N, Morton A, Beardslee K, McMillan B, et al. Piscine orthoreovirus sequences in escaped farmed Atlantic salmon in Washington and British Columbia. Virol J. 2019;16:41 pubmed publisher
    ..This study emphasizes the need to screen Atlantic salmon broodstock for PRV, particularly where used to supply eggs to the global Atlantic salmon farming industry thereby improving our understanding of PRV epidemiology. ..
  2. Kibenge F. Emerging viruses in aquaculture. Curr Opin Virol. 2019;34:97-103 pubmed publisher
  3. request reprint
    Kibenge F, Kibenge M, Groman D, McGeachy S. In vivo correlates of infectious salmon anemia virus pathogenesis in fish. J Gen Virol. 2006;87:2645-52 pubmed
    ..The identified pathogenicity phenotypes may aid in the identification of molecular markers of ISAV virulence. ..
  4. Kibenge F, Xu H, Kibenge M, Qian B, Joseph T. Characterization of gene expression on genomic segment 7 of infectious salmon anaemia virus. Virol J. 2007;4:34 pubmed
    ..The 18-kDa (7-ORF1/2) protein is identified as the putative ISAV nuclear export protein based on the presence of nuclear export signals. The function of the 9.5-kDa (7-ORF1/3) protein is not presently known. ..
  5. request reprint
    Kibenge F, Kibenge M, Wang Y, Qian B, Hariharan S, McGeachy S. Mapping of putative virulence motifs on infectious salmon anemia virus surface glycoprotein genes. J Gen Virol. 2007;88:3100-11 pubmed
    ..This direction of evolution supports insertion of specific motifs in the HE protein, resulting in ISAV attenuation. ..
  6. Kibenge F, Godoy M, Wang Y, Kibenge M, Gherardelli V, Mansilla S, et al. Infectious salmon anaemia virus (ISAV) isolated from the ISA disease outbreaks in Chile diverged from ISAV isolates from Norway around 1996 and was disseminated around 2005, based on surface glycoprotein gene sequences. Virol J. 2009;6:88 pubmed publisher
    ..Taken together, these findings suggest that the ISA outbreaks were caused by virus that was already present in Chile that mutated to new strains. This is the first comprehensive report tracing ISAV from Europe to South America. ..
  7. Godoy M, Suarez R, Lazo E, Llegues K, Kibenge M, Wang Y, et al. Genetic analysis and comparative virulence of infectious salmon anemia virus (ISAV) types HPR7a and HPR7b from recent field outbreaks in Chile. Virol J. 2014;11:204 pubmed publisher
    ..Our findings provide evidence of continuing evolution of ISAV in the Chilean aquaculture industry. ..
  8. Kibenge M, Iwamoto T, Wang Y, Morton A, Routledge R, Kibenge F. Discovery of variant infectious salmon anaemia virus (ISAV) of European genotype in British Columbia, Canada. Virol J. 2016;13:3 pubmed publisher
    ..Our results further suggest that ISAV-HPRΔ strains can be present without clinical disease in farmed fish and without being detected by virus isolation using fish cell lines. ..
  9. Godoy M, Kibenge M, Wang Y, Suarez R, Leiva C, Vallejos F, et al. First description of clinical presentation of piscine orthoreovirus (PRV) infections in salmonid aquaculture in Chile and identification of a second genotype (Genotype II) of PRV. Virol J. 2016;13:98 pubmed publisher
    ..The Chilean PRV strains from coho salmon are more genetically diversified than those from Atlantic salmon, and some form a distinct new phylogenetic cluster, designated Genotype II. ..

More Information


  1. Granger Joly de Boissel P, Fournier M, Rodriguez Lecompte J, McKenna P, Kibenge F, Siah A. Functional and molecular responses of the blue mussel Mytilus edulis' hemocytes exposed to cadmium - An in vitro model and transcriptomic approach. Fish Shellfish Immunol. 2017;67:575-585 pubmed publisher
    ..Further investigations need to be pursued to unravel the effects of Cd on the molecular mechanisms identified in this study. ..
  2. Kibenge F, Qian B, Nagy E, Cleghorn J, Wadowska D. Formation of virus-like particles when the polyprotein gene (segment A) of infectious bursal disease virus is expressed in insect cells. Can J Vet Res. 1999;63:49-55 pubmed
  3. Kibenge F, Godoy M, Fast M, Workenhe S, Kibenge M. Countermeasures against viral diseases of farmed fish. Antiviral Res. 2012;95:257-81 pubmed publisher
  4. request reprint
    Kibenge F, Whyte S, Hammell K, Rainnie D, Kibenge M, Martin C. A dual infection of infectious salmon anaemia (ISA) virus and a togavirus-like virus in ISA of Atlantic salmon Salmo salar in New Brunswick, Canada. Dis Aquat Organ. 2000;42:11-5 pubmed
    ..This study confirms that the original ISA outbreaks in New Brunswick, Canada, were caused solely by ISAV...
  5. request reprint
    Kibenge F, Gárate O, Johnson G, Arriagada R, Kibenge M, Wadowska D. Isolation and identification of infectious salmon anaemia virus (ISAV) from Coho salmon in Chile. Dis Aquat Organ. 2001;45:9-18 pubmed
    ..This outbreak, which produced high mortality in Coho salmon due to ISAV, is unique and may represent the introduction of the virus to a native wild fish population or a new strain of ISAV. ..
  6. Kibenge M, Iwamoto T, Wang Y, Morton A, Godoy M, Kibenge F. Whole-genome analysis of piscine reovirus (PRV) shows PRV represents a new genus in family Reoviridae and its genome segment S1 sequences group it into two separate sub-genotypes. Virol J. 2013;10:230 pubmed publisher
    ..The Canadian PRV diverged from Norwegian sub-genotype Ia around 2007?±?1, whereas the Chilean PRV diverged from Norwegian sub-genotype Ib around 2008?±?1. ..