K M Khan

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. ncbi request reprint Overuse tendinosis, not tendinitis part 1: a new paradigm for a difficult clinical problem
    K M Khan
    Allan McGavin Sports Medicine Centre, University of British Columbia, Vancouver, BC, V6T 1Z1, Can
    Phys Sportsmed 28:38-48. 2000
  2. ncbi request reprint Histopathology of common tendinopathies. Update and implications for clinical management
    K M Khan
    School of Human Kinetics, University of British Columbia, Vancouver, Canada
    Sports Med 27:393-408. 1999
  3. pmc Are ultrasound and magnetic resonance imaging of value in assessment of Achilles tendon disorders? A two year prospective study
    K M Khan
    Department of Family Practice, University of British Columbia, Vancouver, BC, Canada
    Br J Sports Med 37:149-53. 2003
  4. pmc New criteria for female athlete triad syndrome? As osteoporosis is rare, should osteopenia be among the criteria for defining the female athlete triad syndrome?
    K M Khan
    Department of Family Practice, University of British Columbia, Vancouver, Canada
    Br J Sports Med 36:10-3. 2002
  5. doi request reprint Does a novel school-based physical activity model benefit femoral neck bone strength in pre- and early pubertal children?
    H M Macdonald
    Department of Orthopaedics, University of British Columbia, 302 2647 Willow St, Vancouver, BC, Canada, V5Z 3P1
    Osteoporos Int 19:1445-56. 2008
  6. ncbi request reprint A school-based exercise intervention augments bone mineral accrual in early pubertal girls
    K J MacKelvie
    School of Human Kinetics, University of British Columbia, Vancouver, Canada
    J Pediatr 139:501-8. 2001
  7. ncbi request reprint Lifestyle risk factors for osteoporosis in Asian and Caucasian girls
    K J MacKelvie
    School of Human Kinetics, University of British Columbia, Vancouver, BC, Canada
    Med Sci Sports Exerc 33:1818-24. 2001
  8. pmc Increased versican content is associated with tendinosis pathology in the patellar tendon of athletes with jumper's knee
    A Scott
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Scand J Med Sci Sports 18:427-35. 2008
  9. pmc Results of a 10 week community based strength and balance training programme to reduce fall risk factors: a randomised controlled trial in 65-75 year old women with osteoporosis
    N D Carter
    BC Women's Hospital and Health Centre Osteoporosis Program and Faculty of Medicine, University of British Columbia, Vancouver, Canada
    Br J Sports Med 35:348-51. 2001
  10. pmc Does frequency of resistance training affect tibial cortical bone density in older women? A randomized controlled trial
    M C Ashe
    Center for Hip Health and Mobility, 7F 2635 Laurel Street, Vancouver, BC, V5Z 1M9, Canada
    Osteoporos Int 24:623-32. 2013

Collaborators

Detail Information

Publications52

  1. ncbi request reprint Overuse tendinosis, not tendinitis part 1: a new paradigm for a difficult clinical problem
    K M Khan
    Allan McGavin Sports Medicine Centre, University of British Columbia, Vancouver, BC, V6T 1Z1, Can
    Phys Sportsmed 28:38-48. 2000
    ..These include adaptation of advice given when counseling, interaction with the physical therapist and athletic trainer, interpretation of imaging, choice of conservative management, and consideration of whether surgery is an option...
  2. ncbi request reprint Histopathology of common tendinopathies. Update and implications for clinical management
    K M Khan
    School of Human Kinetics, University of British Columbia, Vancouver, Canada
    Sports Med 27:393-408. 1999
    ..We conclude that effective treatment of athletes with tendinopathies must target the most common underlying histopathology, tendinosis, a noninflammatory condition...
  3. pmc Are ultrasound and magnetic resonance imaging of value in assessment of Achilles tendon disorders? A two year prospective study
    K M Khan
    Department of Family Practice, University of British Columbia, Vancouver, BC, Canada
    Br J Sports Med 37:149-53. 2003
    ....
  4. pmc New criteria for female athlete triad syndrome? As osteoporosis is rare, should osteopenia be among the criteria for defining the female athlete triad syndrome?
    K M Khan
    Department of Family Practice, University of British Columbia, Vancouver, Canada
    Br J Sports Med 36:10-3. 2002
  5. doi request reprint Does a novel school-based physical activity model benefit femoral neck bone strength in pre- and early pubertal children?
    H M Macdonald
    Department of Orthopaedics, University of British Columbia, 302 2647 Willow St, Vancouver, BC, Canada, V5Z 3P1
    Osteoporos Int 19:1445-56. 2008
    ..Our intervention also enhanced bone mass accrual by 2-4% at the lumbar spine and total body in boys...
  6. ncbi request reprint A school-based exercise intervention augments bone mineral accrual in early pubertal girls
    K J MacKelvie
    School of Human Kinetics, University of British Columbia, Vancouver, Canada
    J Pediatr 139:501-8. 2001
    ..05); gain at other sites did not differ. CONCLUSIONS: In girls, early puberty may be a particularly opportune time during growth for simple exercise interventions to have a positive effect on bone health...
  7. ncbi request reprint Lifestyle risk factors for osteoporosis in Asian and Caucasian girls
    K J MacKelvie
    School of Human Kinetics, University of British Columbia, Vancouver, BC, Canada
    Med Sci Sports Exerc 33:1818-24. 2001
    ..CONCLUSION: Thus, there was greater ethnic disparity in lifestyle factors related to bone health and absolute measures of bone mineral with advanced maturity...
  8. pmc Increased versican content is associated with tendinosis pathology in the patellar tendon of athletes with jumper's knee
    A Scott
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Scand J Med Sci Sports 18:427-35. 2008
    ....
  9. pmc Results of a 10 week community based strength and balance training programme to reduce fall risk factors: a randomised controlled trial in 65-75 year old women with osteoporosis
    N D Carter
    BC Women's Hospital and Health Centre Osteoporosis Program and Faculty of Medicine, University of British Columbia, Vancouver, Canada
    Br J Sports Med 35:348-51. 2001
    ..However, trends toward improvement in key independent risk factors for falling suggest that a study with greater power may show that these variables can be improved to a level that reaches statistical significance...
  10. pmc Does frequency of resistance training affect tibial cortical bone density in older women? A randomized controlled trial
    M C Ashe
    Center for Hip Health and Mobility, 7F 2635 Laurel Street, Vancouver, BC, V5Z 1M9, Canada
    Osteoporos Int 24:623-32. 2013
    ..There was no mean difference in change in tibial cortical vBMD in older women who engaged in resistance training (RT) one or two times/week compared with the control group over 12 months after adjusting for baseline values...
  11. ncbi request reprint Hand dominance and bone response after a distal radial fracture: a peripheral QCT study
    M C Ashe
    University of British Columbia, Vancouver, British Columbia, Canada
    J Clin Densitom 10:93-101. 2007
    ..This cross-sectional study suggests that the bone response to a nondominant fracture may differ from a dominant fracture...
  12. doi request reprint Muscle power is related to tibial bone strength in older women
    M C Ashe
    Centre for Hip Health and Mobility, Vancouver, BC, Canada
    Osteoporos Int 19:1725-32. 2008
    ..9% in the section modulus after accounting for age, height, weight, and physical activity; moderate to vigorous physical activity was related to muscle power in the lower extremity...
  13. ncbi request reprint Bone geometric response to chronic disuse following stroke: a pQCT study
    M C Ashe
    Department of Family Practice, University of British Columbia, Vancouver, British Columbia, Canada V6T 1V6
    J Musculoskelet Neuronal Interact 6:226-33. 2006
    ..The objectives of this study were to 1) assess volumetric bone geometry and density at the distal radius of individuals with chronic stroke and 2) assess whether bone strength is associated with measures of muscle strength and impairment...
  14. pmc "Bounce at the Bell": a novel program of short bouts of exercise improves proximal femur bone mass in early pubertal children
    H A McKay
    University of British Columbia, 588 828 West 10th Ave, Vancouver, BC, V52 1L8, Canada
    Br J Sports Med 39:521-6. 2005
    ..To examine the effects of a simple and inexpensive physical activity intervention on change in bone mass and structure in school aged children...
  15. doi request reprint Economic evaluation of dose-response resistance training in older women: a cost-effectiveness and cost-utility analysis
    J C Davis
    Centre for Hip Health and Mobility, University of British Columbia, Vancouver, Canada
    Osteoporos Int 22:1355-66. 2011
    ..Both resistance training interventions were more likely to save health care resource money and offer better health outcomes for falls prevention than balance and tone classes...
  16. pmc A randomised clinical trial of the efficacy of drop squats or leg extension/leg curl exercises to treat clinically diagnosed jumper's knee in athletes: pilot study
    L J Cannell
    The Allan McGavin Sports Medicine Centre and School of Human Kinetics, University of British Columbia, Vancouver, Canada
    Br J Sports Med 35:60-4. 2001
    ..To compare the therapeutic effect of two different exercise protocols in athletes with jumper's knee...
  17. doi request reprint SF-6D and EQ-5D result in widely divergent incremental cost-effectiveness ratios in a clinical trial of older women: implications for health policy decisions
    J C Davis
    Centre for Clinical Epidemiology and Evaluation, VCH Research Institute, The University of British Columbia, Research Pavilion, 7th Floor, 828 West 10th Avenue, Vancouver, BC, V5Z 1M9, Canada
    Osteoporos Int 23:1849-57. 2012
    ..We found that the incremental QALYs estimated from the SF-6D were two- to threefold greater than those estimated from the EQ-5D...
  18. doi request reprint Does a home-based strength and balance programme in people aged > or =80 years provide the best value for money to prevent falls? A systematic review of economic evaluations of falls prevention interventions
    J C Davis
    Centre for Hip Health and Mobility, University of British Columbia and Vancouver Coastal Health Research Institute, Vancouver, Canada
    Br J Sports Med 44:80-9. 2010
    ..To investigate the value for money of strategies to prevent falls in older adults living in the community...
  19. ncbi request reprint Muscle cross-sectional area is associated with specific site of bone in prepubertal girls: a quantitative magnetic resonance imaging study
    A Heinonen
    School of Human Kinetics, University of British Columbia, Vancouver, Canada
    Bone 29:388-92. 2001
    ..This relationship was present in a regional, site-specific fashion...
  20. doi request reprint International comparison of cost of falls in older adults living in the community: a systematic review
    J C Davis
    Centre for Hip Health and Mobility, University of British Columbia, Vancouver, Canada
    Osteoporos Int 21:1295-306. 2010
    ..Our systematic review emphasized the need for a consensus on methodology for cost of falls studies to enable more accurate comparisons and subgroup-specific estimates among different countries...
  21. ncbi request reprint Exercise in the prevention of falls in older people: a systematic literature review examining the rationale and the evidence
    N D Carter
    Department of Family Practice, University of British Columbia, Vancouver, Canada
    Sports Med 31:427-38. 2001
    ..Further investigation, using trials designed with the current limitations in mind, is necessary to establish the optimum exercise programme to maximise fall prevention in older adults...
  22. pmc High strain mechanical loading rapidly induces tendon apoptosis: an ex vivo rat tibialis anterior model
    A Scott
    Department of Family Practice and School of Human Kinetics, University of British Columbia, Vancouver, Canada
    Br J Sports Med 39:e25. 2005
    ..The role of apoptosis, or programmed cell death, has only recently been explored in tendon...
  23. ncbi request reprint Accuracy of pQCT for evaluating the aged human radius: an ashing, histomorphometry and failure load investigation
    M C Ashe
    Department of Family Practice, University of British Columbia, Suite 320 5950 University Blvd, Vancouver, British Columbia, Canada, V6T 1Z3
    Osteoporos Int 17:1241-51. 2006
    ..However, in a compromised osteoporotic bone, thin cortices and low scan resolution can limit accurate analysis...
  24. ncbi request reprint Community-dwelling seniors who present to the emergency department with a fall do not receive Guideline care and their fall risk profile worsens significantly: a 6-month prospective study
    A E Salter
    UBC Bone Health Research Group, Centre for Hip Health, Department of Orthopaedics, University of British Columbia and Vancouver Coastal Health Research Institute, Vancouver, B C, Canada
    Osteoporos Int 17:672-83. 2006
    ..Fall risk is a major contributor to fracture risk; implementing fall reduction programmes remains a challenge for health professionals and policy-makers...
  25. pmc The VISA-A questionnaire: a valid and reliable index of the clinical severity of Achilles tendinopathy
    J M Robinson
    Department of Family Practice, University of British Columbia, Vancouver, Canada
    Br J Sports Med 35:335-41. 2001
    ..The test is not designed to be diagnostic. Further studies are needed to determine whether the VISA-A score predicts prognosis...
  26. pmc What do we mean by the term "inflammation"? A contemporary basic science update for sports medicine
    A Scott
    University of British Columbia, Vancouver, Canada
    Br J Sports Med 38:372-80. 2004
    ....
  27. doi request reprint Increased mast cell numbers in human patellar tendinosis: correlation with symptom duration and vascular hyperplasia
    A Scott
    Department of Medicine, University of British Columbia, Vancouver, Canada
    Br J Sports Med 42:753-7. 2008
    ..It has been suggested that because of the close anatomical associations between mast cells and vessels in connective tissues, mast cells may mediate the development of tendon hypervascularity or oedema...
  28. ncbi request reprint Change in lean body mass is a major determinant of change in areal bone mineral density of the proximal femur: a 12-year observational study
    T Liu-Ambrose
    UBC Bone Health Research Group Centre for Hip Health, BC Women s Hospital and Health Centre Osteoporosis Program, and Faculty of Medicine, University of British Columbia, 828 West 10th Avenue, Vancouver, BC, Canada, V5Z 1L8
    Calcif Tissue Int 79:145-51. 2006
    ..These novel longitudinal data highlight the important contribution of LBM to the maintenance of proximal femur bone mass at a key time in women's life span, the years surrounding menopause...
  29. pmc Is there a critical period for bone response to weight-bearing exercise in children and adolescents? a systematic review
    K J MacKelvie
    School of Human Kinetics, University of British Columbia, 6081 University Boulevard, Vancouver, BC V6T 1Z1, Canada
    Br J Sports Med 36:250-7; discussion 257. 2002
    ..The effects of hormonal factors and growth on bone mineral change during puberty are examined, and the possibility of a critical period during which bone is especially adaptable to exercise is discussed...
  30. pmc Exercise interventions for health: time to focus on dimensions, delivery, and dollars
    H A McKay
    School of Human Kinetics, University of British Columbia, Vancouver, BC V6T 1Z1, Canada
    Br J Sports Med 37:98-9. 2003
  31. doi request reprint The cost of fall related presentations to the ED: a prospective, in-person, patient-tracking analysis of health resource utilization
    J C Woolcott
    Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
    Osteoporos Int 23:1513-9. 2012
    ..Using data collected on 102 falls, we found the average cost per fall causing an Emergency Department presentation of $11,408. When hospitalization was required, the average cost per fall was $29,363...
  32. ncbi request reprint Bone mineral response to a 7-month randomized controlled, school-based jumping intervention in 121 prepubertal boys: associations with ethnicity and body mass index
    K J MacKelvie
    School of Human Kinetics, University of British Columbia, Vancouver, Canada
    J Bone Miner Res 17:834-44. 2002
    ..In summary, jumping exercise augmented bone mineral accrual at several regions equally in prepubertal Asian and white boys of average or low BMI, and intervention effects on bone mineral were undetectable in high BMI prepubertal boys...
  33. ncbi request reprint A randomized school-based jumping intervention confers site and maturity-specific benefits on bone structural properties in girls: a hip structural analysis study
    M A Petit
    School of Human Kinetics, University of British Columbia, Vancouver, Canada
    J Bone Miner Res 17:363-72. 2002
    ..0%, p = 0.04), but not at the IT region. There were no differences at the primarily cortical FS. These data provide insight into geometric changes that underpin exercise-associated gain in bone strength in early-pubertal girls...
  34. pmc Mechanotherapy: how physical therapists' prescription of exercise promotes tissue repair
    K M Khan
    Centre for Hip Health and Mobility and Department of Family Practice, University of British Columbia, Vancouver, Canada
    Br J Sports Med 43:247-52. 2009
    ..After first outlining the process of mechanotransduction, we provide well-known clinical therapeutic examples of mechanotherapy-turning movement into tissue healing...
  35. pmc The de morton mobility index: normative data for a clinically useful mobility instrument
    E M Macri
    Centre for Hip Health and Mobility, University of British Columbia, Vancouver, BC, Canada V5Z 1M9
    J Aging Res 2012:353252. 2012
    ..49) or reported falls history (P = 0.21). Normative data for the DEMMI mobility instrument provides vital reference scores to facilitate its use across the mobility spectrum in clinical, research, and policymaking settings...
  36. pmc Body position affects performance in untrained cyclists
    M C Ashe
    University of British Columbia, Vancouver, BC, Canada
    Br J Sports Med 37:441-4. 2003
    ..To compare cardiovascular and ventilatory variables in upright versus aero cycle ergometry at submaximal and maximal exercise intensities in untrained cyclists...
  37. pmc Balance confidence improves with resistance or agility training. Increase is not correlated with objective changes in fall risk and physical abilities
    T Liu-Ambrose
    School of Human Kinetics, University of British Columbia, Vancouver, Canada
    Gerontology 50:373-82. 2004
    ..However, there are no prospective reports that correlate change in balance confidence with changes in fall risk and physical abilities as induced by participating in a group-based exercise program...
  38. ncbi request reprint The effects of proprioceptive or strength training on the neuromuscular function of the ACL reconstructed knee: a randomized clinical trial
    T Liu-Ambrose
    School of Human Kinetics, University of British Columbia, Canada
    Scand J Med Sci Sports 13:115-23. 2003
    ..a strength training (ST) program on neuromuscular function after anterior cruciate ligament (ACL) reconstruction. The second purpose was to establish the determinants of functional ability for the operated limb...
  39. pmc What is "inflammation"? Are we ready to move beyond Celsus?
    A Scott
    University of British Columbia, Vancouver, Canada
    Br J Sports Med 38:248-9. 2004
  40. pmc Ground reaction forces associated with an effective elementary school based jumping intervention
    H McKay
    Department of Family Practice and Orthopaedics, Faculty of Medicine, University of British Columbia, Vancouver, Canada
    Br J Sports Med 39:10-4. 2005
    ..Ground reaction forces (GRFs) may provide a surrogate measure for the strain experienced by bone on landing and at take off. However, there appear to be no paediatric studies that assess GRFs across a variety of loading activities...
  41. ncbi request reprint The influence of back pain on balance and functional mobility in 65- to 75-year-old women with osteoporosis
    T Liu-Ambrose
    Fall Free BC Research Group, BC Women s Hospital, University of British Columbia, Vancouver, Canada
    Osteoporos Int 13:868-73. 2002
    ..Prospective studies are needed to determine whether pain management will improve balance and functional mobility...
  42. ncbi request reprint Effect of nutrition and body composition on bone density after liver transplantation
    K M Khan
    Department of Pediatrics University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transplant Proc 39:3292-4. 2007
    ..We investigated the relationship between nutrition, body composition, and bone mineral density (BMD) in young adults after liver transplantation...
  43. ncbi request reprint Dancing for bone health: a 3-year longitudinal study of bone mineral accrual across puberty in female non-elite dancers and controls
    B L Matthews
    Centre for Health, Exercise and Sports Medicine School of Physiotherapy, The University of Melbourne, Melbourne, Victoria 3010, Australia
    Osteoporos Int 17:1043-54. 2006
    ..However, the window of opportunity for optimizing positive effects of exercise on peak bone mass remains to be fully defined. Ballet dancing provides a model of mechanical loading patterns required to site-specifically modulate bone...
  44. ncbi request reprint Outcome of surgery for chronic Achilles tendinopathy. A critical review
    C Tallon
    Department of Orthopaedic Surgery, University of Aberdeen Medical School, Scotland
    Am J Sports Med 29:315-20. 2001
    ..01). Study methods may influence reported surgical outcome, and we suggest guidelines for improving study design in this area of clinical research. We acknowledge that study methods have improved over the course of the past 20 years...
  45. ncbi request reprint Epidural abscess and vertebral osteomyelitis caused by Listeria monocytogenes: case report and literature review
    K M Khan
    Department of Internal Medicine, New York Presbyterian Hospital-Weill Cornell Medical Center, NY 10021, USA
    Scand J Infect Dis 33:714-6. 2001
    ..To our knowledge, no cases of epidural abscess and only 3 cases of osteomyelitis have previously been reported in association with this organism...
  46. ncbi request reprint Role of laminin in matrix induction of macrophage urokinase-type plasminogen activator and 92-kDa metalloproteinase expression
    K M Khan
    Department of Pathology, Cornell University Medical College, New York, New York 10021, USA
    J Biol Chem 272:8270-5. 1997
    ..These results demonstrate that macrophage binding to laminin plays an important role in the regulation of their degradative phenotype via the up-regulation of uPA and MMP-9...
  47. ncbi request reprint Achilles tendinopathy
    J L Cook
    Musculoskeletal Research Centre, La Trobe University, Victoria, Australia
    Man Ther 7:121-30. 2002
    ..Surgical treatment is effective after complete tendon rupture, but may not assist recovery from overuse tendinopathy. Further research into the clinical aspects of Achilles tendinopathy is required...
  48. ncbi request reprint Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) are positioned to modulate afferent signaling in the cochlea
    M J Drescher
    Laboratory of Bio Otology, Department of Otolaryngology, Wayne State University School of Medicine, 261 Lande Medical Research Building, 540 East Canfield Avenue, Detroit, MI 48201, USA
    Neuroscience 142:139-64. 2006
    ..Additionally, PACAP/PAC1-R may modulate secretion of catecholamines from adrenergic terminals within the organ of Corti...
  49. ncbi request reprint Abnormal tenocyte morphology is more prevalent than collagen disruption in asymptomatic athletes' patellar tendons
    J L Cook
    Musculoskeletal Research Centre, La Trobe University, Victoria 3086, Australia
    J Orthop Res 22:334-8. 2004
    ..No tendons demonstrated neovascularization. It appears that cellular changes must be present if there is an increase in ground substance, or collagen and vascular changes. Further research is required to confirm these findings...
  50. pmc Anthropometry, physical performance, and ultrasound patellar tendon abnormality in elite junior basketball players: a cross-sectional study
    J L Cook
    Musculoskeletal Research Centre, La Trobe University, Bundoora, VIC 3083, Australia
    Br J Sports Med 38:206-9. 2004
    ..This cross-sectional study examined the anthropometric and physical performance results of elite junior basketball players with normal or abnormal patellar tendons to see if any measures were associated with changes in tendon morphology...
  51. pmc Risk factors associated with exertional medial tibial pain: a 12 month prospective clinical study
    S G Burne
    University of NSW, Birchgrove, New South Wales, Australia
    Br J Sports Med 38:441-5. 2004
    ..To investigate in a military setting the potential role of intrinsic biomechanical and anthropometric risk factors for, and the incidence of, exertional medial tibial pain (EMTP)...
  52. doi request reprint International Olympic Committee consensus statement: molecular basis of connective tissue and muscle injuries in sport
    Arne Ljungqvist
    International Olympic Committee Medical Commission, Lausanne, Switzerland
    Clin Sports Med 27:231-9, x-xi. 2008
    ..The International Olympic Committee (IOC) now has high-level scientific advisors who can advise the IOC as to the use and abuse of these technologies...