Andrew Kertesz

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Frontotemporal dementia: one disease, or many?: probably one, possibly two
    Andrew Kertesz
    Cognitive Neurology, Department of Psychology, Social Science Centre, SSC 7418, University of Western Ontario, London, Ontario
    Alzheimer Dis Assoc Disord 19:S19-24. 2005
  2. ncbi Progress in clinical neurosciences: Frontotemporal dementia-pick's disease
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St. Joseph's Hospital, University of Western Ontario, London, Ontario, Canada
    Can J Neurol Sci 33:141-8. 2006
  3. ncbi Frontotemporal dementia
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St Joseph s Hospital, University of Western Ontario, 268 Grosvenor Street, London, Ontario N6A 4V2, Canada
    Med Clin North Am 86:501-18, vi. 2002
  4. ncbi The aphasia quotient: the taxonomic approach to measurement of aphasic disability. 1974
    Andrew Kertesz
    Department of Clinical Neurological Sciences, University of Western Ontario, St. Joseph's Hospital, London, Ontario, Canada
    Can J Neurol Sci 31:175-84. 2004
  5. ncbi Quantitative and qualitative analyses of clock drawing in frontotemporal dementia and Alzheimer's disease
    Mervin Blair
    Department of Cognitive Neurology, St Joseph s Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2
    J Int Neuropsychol Soc 12:159-65. 2006
  6. ncbi Relationship between frontotemporal dementia and corticobasal degeneration/progressive supranuclear palsy
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St Joseph s Hospital, University of Western Ontario, London, Ont, Canada
    Dement Geriatr Cogn Disord 17:282-6. 2004
  7. ncbi Historical notes on the World Federation of Neurology Research Group on Aphasia and Cognitive Disorders (RGACD)
    Andrew Kertesz
    University of Western Ontario, St Joseph s Hospital, 268 Grosvenor St, London, Ontario, Canada N6A4V2
    J Neurol Sci 298:132-5. 2010
  8. ncbi Frontotemporal dementia/Pick's disease
    Andrew Kertesz
    Department of Clinical Neurological Sciences, University of Western Ontario, St Joseph's Hospital, London, Ontario, Canada
    Arch Neurol 61:969-71. 2004
  9. ncbi Frontotemporal dementia, Pick's disease
    Andrew Kertesz
    University of Western Ontario, St Joseph s Hospital, 268 Grosvenor St London, Ontario, Canada N6A4V2
    Ideggyogy Sz 63:4-12. 2010
  10. ncbi The evolution and pathology of frontotemporal dementia
    Andrew Kertesz
    Department of Cognitive Neurology, St Joseph s Hospital, London, Ontario N6A 4V2, Canada
    Brain 128:1996-2005. 2005

Detail Information

Publications59

  1. ncbi Frontotemporal dementia: one disease, or many?: probably one, possibly two
    Andrew Kertesz
    Cognitive Neurology, Department of Psychology, Social Science Centre, SSC 7418, University of Western Ontario, London, Ontario
    Alzheimer Dis Assoc Disord 19:S19-24. 2005
    ..The overlap between them is too great to establish two separate diseases...
  2. ncbi Progress in clinical neurosciences: Frontotemporal dementia-pick's disease
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St. Joseph's Hospital, University of Western Ontario, London, Ontario, Canada
    Can J Neurol Sci 33:141-8. 2006
    ..However the overlap is too great to split the disease. A glossary to navigate the proliferating terminology is included...
  3. ncbi Frontotemporal dementia
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St Joseph s Hospital, University of Western Ontario, 268 Grosvenor Street, London, Ontario N6A 4V2, Canada
    Med Clin North Am 86:501-18, vi. 2002
    ..This article emphasizes the considerable overlap among the different varieties of frontotemporal dementia, as well as the distinctive features of each...
  4. ncbi The aphasia quotient: the taxonomic approach to measurement of aphasic disability. 1974
    Andrew Kertesz
    Department of Clinical Neurological Sciences, University of Western Ontario, St. Joseph's Hospital, London, Ontario, Canada
    Can J Neurol Sci 31:175-84. 2004
    ..This classification is considered a clinically valid baseline for research, diagnosis and prognosis...
  5. ncbi Quantitative and qualitative analyses of clock drawing in frontotemporal dementia and Alzheimer's disease
    Mervin Blair
    Department of Cognitive Neurology, St Joseph s Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2
    J Int Neuropsychol Soc 12:159-65. 2006
    ..In conclusion, both global and error analysis of the CDT helped discriminate the FTD group from controls and AD patients...
  6. ncbi Relationship between frontotemporal dementia and corticobasal degeneration/progressive supranuclear palsy
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St Joseph s Hospital, University of Western Ontario, London, Ont, Canada
    Dement Geriatr Cogn Disord 17:282-6. 2004
    ..The overlap of CBD with PSP and both with PPA and FTD allows to consider these relatively rare conditions as part of a more commonly occurring degenerative disease than previously recognized...
  7. ncbi Historical notes on the World Federation of Neurology Research Group on Aphasia and Cognitive Disorders (RGACD)
    Andrew Kertesz
    University of Western Ontario, St Joseph s Hospital, 268 Grosvenor St, London, Ontario, Canada N6A4V2
    J Neurol Sci 298:132-5. 2010
    ..The purpose is to achieve continuity between the past and present and to document the collective memories of the activities of the group, hereby strengthening its future...
  8. ncbi Frontotemporal dementia/Pick's disease
    Andrew Kertesz
    Department of Clinical Neurological Sciences, University of Western Ontario, St Joseph's Hospital, London, Ontario, Canada
    Arch Neurol 61:969-71. 2004
  9. ncbi Frontotemporal dementia, Pick's disease
    Andrew Kertesz
    University of Western Ontario, St Joseph s Hospital, 268 Grosvenor St London, Ontario, Canada N6A4V2
    Ideggyogy Sz 63:4-12. 2010
    ..Tau and progranulin mutations on Ch-17 and some others, point to molecular mechanisms. A glossary is provided to navigate the complex terminology...
  10. ncbi The evolution and pathology of frontotemporal dementia
    Andrew Kertesz
    Department of Cognitive Neurology, St Joseph s Hospital, London, Ontario N6A 4V2, Canada
    Brain 128:1996-2005. 2005
    ....
  11. ncbi What is semantic dementia?: a cohort study of diagnostic features and clinical boundaries
    Andrew Kertesz
    Department of Clinical Neurological Sciences, University of Western Ontario, 268 Grosvenor St, London, ON N6A 4V2
    Arch Neurol 67:483-9. 2010
    ..To describe a large, clinically defined cohort of patients with semantic dementia (SD) that highlights important, sometimes overlooked features and to compare it with similar entities...
  12. ncbi Behavior and cognition in corticobasal degeneration and progressive supranuclear palsy
    Andrew Kertesz
    Dept of Cognitive Neurology, University of Western Ontario, St Joseph s Hospital, Ontario, Canada
    J Neurol Sci 289:138-43. 2010
    ..The clinical, genetic and pathological relationship is strong between CBD /PSP and the aphasic and behavioral components of the Pick complex...
  13. ncbi Clinical features and diagnosis of frontotemporal dementia
    Andrew Kertesz
    St Joseph s Hospital, University of Western Ontario, London, Ontario, Canada
    Front Neurol Neurosci 24:140-8. 2009
    ....
  14. ncbi The diagnosis and course of frontotemporal dementia
    Andrew Kertesz
    Cognitive Neurology, St Joseph s Hospital, London, and Department of Pathology, University of Western Ontario, Canada
    Alzheimer Dis Assoc Disord 21:155-63. 2007
    ..In conclusion, the clinical associations follow the tau-negative and tau-positive pathologic dichotomy to some extent, but there is too much overlap to consider the clinical groups or their associations separate diseases...
  15. ncbi Galantamine in frontotemporal dementia and primary progressive aphasia
    A Kertesz
    Cognitive Neurology and Alzheimer Research Centre, St Joseph s Hospital, London, Ont, USA
    Dement Geriatr Cogn Disord 25:178-85. 2008
    ..The treatment of frontotemporal dementia (FTD) has been mainly symptomatic. Small randomized or open-label case control studies of neurotransmitters have been inconclusive. We tried galantamine in the 2 most common varieties of FTD...
  16. ncbi Behavioral quantitation is more sensitive than cognitive testing in frontotemporal dementia
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St Joseph s Health Care London, Saint Joseph s Hospital, University of Western Ontario, London, Ontario N6A 4V2, Canada
    Alzheimer Dis Assoc Disord 17:223-9. 2003
    ..To compare behavioral and cognitive testing in the clinical diagnosis of frontotemporal dementia (FTD)...
  17. ncbi Pick Complex: an integrative approach to frontotemporal dementia: primary progressive aphasia, corticobasal degeneration, and progressive supranuclear palsy
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St Joseph s Hospital, University of Western Ontario, London, Ontario, Canada
    Neurologist 9:311-7. 2003
    ..Recently, chromosome 17 localization and tau mutations were discovered in familial forms of the disease...
  18. ncbi Primary progressive aphasia and Pick complex
    Andrew Kertesz
    Department of Clinical Neurological Sciences, University of Western Ontario, St Joseph s Health Care London, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2
    J Neurol Sci 206:97-107. 2003
    ..This series of autopsied cases provides evidence for the clinical and pathological overlap of PPA with FTD and CBD, and contributes to the diagnostic and neuropsychological definition of PPA...
  19. ncbi Extrapyramidal syndromes in frontotemporal degeneration
    Andrew Kertesz
    Department of Neurology, University of Western Ontario, London, ON, Canada
    J Mol Neurosci 45:336-42. 2011
    ..Cross-sectional studies without significant follow-up may not observe the subsequent development language or behavior deficit, or the evolution from PPA and/or FTD-bv to CBD/PSP...
  20. ncbi Pick complex--historical introduction
    Andrew Kertesz
    Cognitive Neurology Unit, St Joseph s Hospital, University of Western Ontario, London, Ontario, Canada
    Alzheimer Dis Assoc Disord 21:S5-7. 2007
    ..A historical perspective helps to prevent the chaos of terminological confusion and reinventing the wheel...
  21. ncbi Primary progressive aphasia: diagnosis, varieties, evolution
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St Joseph s Health Care London, University of Western Ontario, London, Ontario, Canada
    J Int Neuropsychol Soc 9:710-9. 2003
    ..The fluent-nonfluent dichotomy in PPA is mostly stage related. The aphemic-logopenic-agrammatic and semantic distinction is useful, but the outcomes converge...
  22. ncbi Pick's complex and FTDP-17
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St Joseph s Hospital, University of Western Ontario, London, Ontario, Canada
    Mov Disord 18:S57-62. 2003
    ..Although clinical, pathological, and biochemical distinctions continue to be important, integration promises to be productive in this family of not so rare diseases...
  23. ncbi The overlapping syndromes of the pick complex
    A Kertesz
    Department of Neurology, University of Western Ontario, London, Canada
    Curr Alzheimer Res 8:224-8. 2011
    ..Tau and progranulin mutations on Ch-17 and some others, point to molecular mechanisms. A glossary is provided to navigate the complex terminology...
  24. ncbi Corticobasal degeneration and progressive aphasia
    Paul McMonagle
    Department of Cognitive Neurology, University of Western Ontario, St Joseph s Hospital, London, Ontario, Canada
    Neurology 67:1444-51. 2006
    ....
  25. ncbi A longitudinal study of language decline in Alzheimer's disease and frontotemporal dementia
    Mervin Blair
    Department of Cognitive Neurology, St Joseph s Health Care, London, Ontario, Canada
    J Int Neuropsychol Soc 13:237-45. 2007
    ..In conclusion, longitudinal language assessment provides us with a unique understanding of the evolution and progression of language deterioration in various dementias...
  26. ncbi Category and letter fluency in semantic dementia, primary progressive aphasia, and Alzheimer's disease
    Cecile A Marczinski
    Department of Cognitive Neurology, St Joseph s Hospital, University of Western Ontario, London, Ont, Canada
    Brain Lang 97:258-65. 2006
    ..Fluency tasks, with the richness of data obtained, are valuable in distinguishing different dementia syndromes from one another...
  27. ncbi Neuropsychiatric symptom clusters and functional disability in cognitively-impaired-not-demented individuals
    Kevin R Peters
    Department of Psychology, Trent University, Peterborough, Ontario, Canada
    Am J Geriatr Psychiatry 16:136-44. 2008
    ....
  28. ncbi A longitudinal study of behavior in frontotemporal dementia and primary progressive aphasia
    Cecile A Marczinski
    Department of Clinical Neurological Sciences, St Joseph s Hospital, University of Western Ontario, London, Ontario, Canada
    Cogn Behav Neurol 17:185-90. 2004
    ....
  29. ncbi A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly
    April J Ho
    Laboratory of Neuroimaging, Department of Neurology, University of California School of Medicine, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 107:8404-9. 2010
    ..These brain maps reveal that a commonly carried susceptibility allele for obesity is associated with structural brain atrophy, with implications for the health of the elderly...
  30. ncbi The cognitive profile of posterior cortical atrophy
    Paul McMonagle
    Department of Cognitive Neurology, University of Western Ontario, St Joseph s Hospital, London, Ontario, N6A 4V2, Canada
    Neurology 66:331-8. 2006
    ..Posterior cortical atrophy (PCA) is a progressive dementia characterized by prominent disorders of higher visual processing, affecting both dorsal and ventral streams to cause Balint's syndrome, alexia, and visual agnosia...
  31. ncbi Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease
    David A Wolk
    Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 107:10256-61. 2010
    ....
  32. ncbi Delusions and hallucinations in frontotemporal dementia: a clinicopathologic case report
    Maria Carmela Tartaglia
    Department of Clinical Neurological Sciences, Division of Neurology, St Joseph s Hospital, University of Western Ontario, Ontario, Canada
    Cogn Behav Neurol 21:107-10. 2008
    ..Frontotemporal dementia (FTD) is associated with marked behavior changes, but hallucinations and delusions are rare...
  33. ncbi The effects of oxytocin on social cognition and behaviour in frontotemporal dementia
    Sarah Jesso
    Department of Clinical Neurological Sciences, University of Western Ontario, B10 004, 339 Windermere Rd, London, ON, Canada N6A 5A5
    Brain 134:2493-501. 2011
    ....
  34. ncbi The prevalence of misidentification syndromes in neurodegenerative diseases
    Michal Harciarek
    Department of Cognitive Neurology, St Joseph s Hospital, University of Western Ontario, London, Ontario, Canada
    Alzheimer Dis Assoc Disord 22:163-9. 2008
    ..Thus, our findings suggest that MISs are characteristic of AD and DLB, and tend to exclude FTD/Pick complex and PD...
  35. ncbi Argyrophilic thorny astrocyte clusters in association with Alzheimer's disease pathology in possible primary progressive aphasia
    David G Munoz
    Li Ka Shing Knowledge Institute of St Michael s Hospital, University of Toronto, Toronto, ON, Canada
    Acta Neuropathol 114:347-57. 2007
    ....
  36. ncbi Pathologic evaluation of the supraoptic and paraventricular nuclei in dementia
    David Diodati
    Cognitive Neurology and Alzheimer Research Centre, St Joseph s Hospital, Canada
    Can J Neurol Sci 39:213-9. 2012
    ..While patients with Frontotemporal dementia (FTD) display prominent and progressive deficits in such social behaviours, the integrity of these nuclei in FTD is not known...
  37. ncbi Primary progressive aphasia: a review of the neurobiology of a common presentation of Pick complex
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St. Joseph's Health Care, London, Ontario, Canada
    Am J Alzheimers Dis Other Demen 17:30-6. 2002
    ..Several of the cases described with focal Alzheimer's pathology do not fulfill the criteria of PPA, but have Alzheimer's disease with a major aphasic component...
  38. ncbi Preferred terminology
    Andrew Kertesz
    Department of Clinical Neurological Sciences, St. Joseph's Hospital, London, Ontario, Canada
    Ann Neurol 54:S3-6. 2003
  39. ncbi Functional neural correlates of emotional expression processing deficits in behavioural variant frontotemporal dementia
    Karim Virani
    Graduate Program in Neuroscience, University of Western Ontario, London, Ont
    J Psychiatry Neurosci 38:174-82. 2013
    ..As viewing emotional expressions is known to engage many of the same neural systems that are active when experiencing the emotion itself, fMRI during expression processing provides a novel window into the emotions of patients with FTD...
  40. ncbi Genetic variation in GOLM1 and prefrontal cortical volume in Alzheimer's disease
    Becky Inkster
    GlaxoSmithKline Clinical Imaging Centre, Hammersmith Hospital, London, United Kingdom
    Neurobiol Aging 33:457-65. 2012
    ..The greater effect size in AD patients also suggests that the GG genotype could be a risk factor for the expression of cognitive deficits in AD...
  41. ncbi Voxelwise genome-wide association study (vGWAS)
    Jason L Stein
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles School of Medicine, Neuroscience Research Building 225E, 635 Charles Young Drive, Los Angeles, CA 90095 1769, USA
    Neuroimage 53:1160-74. 2010
    ..These genes have high relevance to brain structure. This is the first voxelwise genome wide association study to our knowledge, and offers a novel method to discover genetic influences on brain structure...
  42. ncbi Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
    Katya Rascovsky
    Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 3 West Gates, Philadelphia, PA 19104, USA
    Brain 134:2456-77. 2011
    ..Future studies will be needed to establish the reliability and specificity of these revised diagnostic guidelines...
  43. ncbi Exploded drawing in posterior cortical atrophy
    Paul McMonagle
    Wessex Neurological Centre, Southampton General Hospital, Tremona Road, Southampton SO16 YD, UK
    Neurology 67:1866. 2006
  44. ncbi A frontotemporal family bridge
    Andrew Kertesz
    Arch Neurol 61:318. 2004
  45. ncbi The Consortium to Investigate Vascular Impairment of Cognition: methods and first findings
    Kenneth Rockwood
    Dalhousie University, Halifax, NS, Canada
    Can J Neurol Sci 30:237-43. 2003
    ..Even for patients who do, the proportion identified with VaD varies widely. Criteria based on empirical analyses need to be developed and validated...
  46. ncbi International approaches to frontotemporal dementia diagnosis: from social cognition to neuropsychology
    Bruce L Miller
    UCSF Memory and Aging Center, San Francisco, CA, USA
    Ann Neurol 54:S7-10. 2003
  47. ncbi Frontotemporal degeneration, Pick's disease, Pick complex, and Ravel
    Andrew Kertesz
    Ann Neurol 54:S1-2. 2003
  48. ncbi Efficacy of galantamine in probable vascular dementia and Alzheimer's disease combined with cerebrovascular disease: a randomized trial
    Andrew Kertesz
    Curr Neurol Neurosci Rep 2:503-4. 2002
  49. ncbi The core and halo of primary progressive aphasia and semantic dementia
    M-Marsel Mesulam
    Cognitive Neurology and Alzheimer's Disease Center and Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Ann Neurol 54:S11-4. 2003
  50. ncbi Gerstmann-Sträussler-Scheinker disease with the Q217R mutation mimicking frontotemporal dementia
    John Woulfe
    Acta Neuropathol 110:317-9. 2005
  51. ncbi Clinical and radiographic subtypes of vascular cognitive impairment in a clinic-based cohort study
    Kenneth Rockwood
    Dalhousie University, Canada
    J Neurol Sci 240:7-14. 2006
    ..There is a need for empirical studies to define criteria for vascular cognitive impairment (VCI) subtypes. In this paper, we report the predictive validity of a subtype classification scheme based on clinical and radiographic features...
  52. ncbi Rate of progression differs in frontotemporal dementia and Alzheimer disease
    Andrew Kertesz
    Neurology 66:1607; author reply 1607. 2006
  53. ncbi Outcomes of cognitively impaired not demented at 2 years in the Canadian Cohort Study of Cognitive Impairment and Related Dementias
    Ging-Yuek R Hsiung
    Division of Neurology, Department of Medicine University of British Columbia, Vancouver, Canada
    Dement Geriatr Cogn Disord 22:413-20. 2006
    ..CONCLUSION: CIND consists of a heterogeneous group of disorders that can be classified syndromically. Many subclassess - not just those with pre-AD CIND - are at high risk of progression to dementia, usually to Alzheimer's disease...
  54. ncbi Disease progression in vascular cognitive impairment: cognitive, functional and behavioural outcomes in the Consortium to Investigate Vascular Impairment of Cognition (CIVIC) cohort study
    Kenneth Rockwood
    Dalhousie University, Canada
    J Neurol Sci 252:106-12. 2007
    ..We compared cognitive, functional, and behavioural outcomes in patients with VCI to patients with no cognitive impairment (NCI), and Alzheimer's disease (AD)...
  55. ncbi Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative
    Rosa Rademakers
    Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA
    Lancet Neurol 6:857-68. 2007
    ..The most common mutation in GRN is Arg493X. We aimed to establish the contribution of this mutation to FTLD and related disorders...
  56. ncbi Transition from cognitively impaired not demented to Alzheimer's disease: an analysis of changes in functional abilities in a dementia clinic cohort
    Ging Yuek R Hsiung
    Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Dement Geriatr Cogn Disord 25:483-90. 2008
    ..We evaluated whether impairments on the Disability Assessment for Dementia (DAD) and Functional Rating Scale (FRS) can predict progression to AD...
  57. ncbi Diagnosis and treatment of dementia: 2. Diagnosis
    Howard H Feldman
    Division of Neurology, Department of Medicine, University of British Columbia, and the University of British Columbia Hospital Clinic for Alzheimer s Disease and Related Disorders, Vancouver, BC
    CMAJ 178:825-36. 2008
    ..In this article, we provide physicians with practical guidance on the diagnosis of dementia based on recommendations from the Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia, held in March 2006...
  58. ncbi Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
    Hao Li
    GlaxoSmithKline, Research Triangle Park, North Carolina, USA
    Arch Neurol 65:45-53. 2008
    ..To identify single-nucleotide polymorphisms (SNPs) associated with risk and age at onset of Alzheimer disease (AD) in a genomewide association study of 469 438 SNPs...
  59. ncbi Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions
    Katya Rascovsky
    Memory and Aging Center, University of California, San Francisco, CA 94117, USA
    Alzheimer Dis Assoc Disord 21:S14-8. 2007
    ..In this article, we discuss the limitations of current diagnostic criteria and propose the establishment of an international consortium to revise diagnostic and research criteria for the behavioral variant of frontotemporal dementia...