W S Kendal

..A population-based analysis of cancer patients was carried out here, comparing suicide risk between the genders, to elucidate the features specific to each gender...

..The observed density patterns, and proposed model, presumably represent the convergent summation of multiple stochastic processes within the evolutionary history of the chromosome...

..To investigate the possible association between pelvic irradiation for rectal cancer and subsequent second primary cancers...

..Cancer survival is influenced by age, comorbidity, and type of cancer. A population-based study was conducted to compare the interplay between age and mortality for different cancers...

..Cancer patients appear at higher risk of accidental death and suicide. The reasons for this and how suicide and accidental death relate remain unclear...

..The Tweedie convergence theorem provides a unified mathematical explanation for the origin of Taylor's law and 1/f noise applicable to a wide range of biological, physical, and mathematical processes, as well as to multifractality...

..Since the number of sampled nodes similarly approximated a negative binomial distribution, random involvement with superimposed population heterogeneity would more credibly explain both sets of observations...

..To investigate a putative increased risk of rectal cancer subsequent to prostatic radiotherapy...

..Here the scientific basis of this assumption will be examined...

..To describe the frequency distribution for the number of residual subclinical metastatic tumor cells after removal of the primary cancer...

..A model for the random gain and loss of metastatic CSC is developed to investigate how the balance between these processes might affect metastatic efficiency, tumour involution and treatment response...

..Assessments like these implicitly assume that spurious effects can be discounted. Here the influence of chance on the burden of metastasis is studied to determine whether or not this assumption is valid...

..Both models were consistent with the hypothesis that the nodal metastasis is a chance event, with the probability of involvement greatest for nodes contiguous to the primary tumor and proportioned by lymphatic flow...

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..56, similar to the corresponding figure from murine lung metastasis. These findings lend support to the hypothesis that the observed clustering of metastases is a consequence of fractal variations in lung blood flow...

..To illustrate how probability-generating functions (PGFs) can be employed to derive a simple probabilistic model for clonogenic survival after exposure to ionizing irradiation...

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..Here an analysis of the physical distribution of gene structures on human chromosome 7 was performed to confirm the presence of clustering, and to elucidate possible underlying statistical and biological mechanisms...

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..These estimates were consistent with measurements from conventional studies. This PG model thus provides an alternative to Monte Carlo simulation for description of the distribution of SNPs...

..To determine how inhomogeneities in blood perfusion might affect the number of metastases that develop within an individual with cancer...

..The precise localization of the prostate is critical for dose-escalated conformal radiotherapy. This study identifies and characterizes a potential cause of inaccurate prostatic localization-respiratory-induced movement...

..These observations supported the hypothesis of normally distributed growth times, and qualified the utility of the lognormal and Gompertz-normal distributions for the size distribution of metastases...

..Because most people who develop local recurrence of colorectal cancer will die from their disease, the main contribution of a multimodality approach may be towards palliation...

..Here the population-based Surveillance, Epidemiology, and End Results (SEER) registry is used to study the survival of renal leiomyosarcomas...