Research Topics
| Padma KaulSummaryAffiliation: University of Alberta Country: Canada Publications
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Detail Information
Publications
Incidence of heart failure and mortality after acute coronary syndromesPadma Kaul
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Am Heart J 165:379-85.e2. 2013..We examined the 1-year incidence of HF and its association with mortality among patients surviving their first acute coronary syndrome (ACS) hospitalization...
Relative prognostic value of baseline Q wave and time from symptom onset among men and women with ST-elevation myocardial infarction undergoing percutaneous coronary interventionPadma Kaul
University of Alberta, Edmonton, Alberta, Canada
Am J Cardiol 110:1555-60. 2012..0 to 2.7) and women (2.3, 1.2 to 4.2). In conclusion, in this gender-specific analysis, baseline Q wave was found be a better marker of risk of 90-day mortality than time from symptom onset to PCI, overall, and especially in women...
Relation between baseline risk and treatment decisions in non-ST elevation acute coronary syndromes: an examination of international practice patternsP Kaul
University of Alberta, Edmonton, Alberta, Canada
Heart 91:876-81. 2005..To examine whether ST segment depression influenced clinical decision making and whether there was international variation in the use of cardiac procedures across ST segment depression categories...
Economic analysis of the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT-3) study: costs of reperfusion strategies in acute myocardial infarctionPadma Kaul
Department of Medicine, Duke Clinical Research Institute, Durham, NC, USA
Am Heart J 149:637-44. 2005....
Optimizing use of revascularization and clinical outcomes in ST-elevation myocardial infarction: insights from the GUSTO-V trialPadma Kaul
University of Alberta, 7, 226 Aberhart Center I, Edmonton, Alberta, Canada T6G 2J3
Eur Heart J 27:1198-206. 2006..To examine the relative contribution of system and patient level factors to the variation in international revascularization rates, and their impact on mortality outcomes...
Assessment of activity status and survival according to the Canadian Cardiovascular Society angina classificationPadma Kaul
Division of Cardiology, University of Alberta, Edmonton, Alberta T6G 2M8, Canada
Can J Cardiol 25:e225-31. 2009..Despite its widespread use, limited data on the validity of the Canadian Cardiovascular Society angina (CCSA) classification relative to other measures of functional status have been reported...
Differences in admission rates and outcomes between men and women presenting to emergency departments with coronary syndromesPadma Kaul
Division of Cardiology, Department of Medicine, and the Canadian VIGOUR Centre, University of Alberta, Edmonton, Alta
CMAJ 177:1193-9. 2007..We sought to examine sex-related differences at an earlier point in care--presentation to the emergency department...
Resource use in the last 6 months of life among patients with heart failure in CanadaPadma Kaul
Department of Medicine, Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
Arch Intern Med 171:211-7. 2011..Heart failure (HF) is a debilitating and chronic condition associated with significant morbidity and mortality. However, much less is known about end-of-life (EOL) costs among patients with HF...
Temporal trends in patient and treatment delay among men and women presenting with ST-elevation myocardial infarctionPadma Kaul
Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Am Heart J 161:91-7. 2011..Whether these have resulted in changes in sex differences in time to treatment is unknown. We examined temporal trends in time to reperfusion therapy among men and women with STEMI...
Long-term mortality of patients with acute myocardial infarction in the United States and Canada: comparison of patients enrolled in Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-IPadma Kaul
University of Alberta, 7221 Aberhart Center I, 8440 112 St, Edmonton, AB T6G 2B7, Canada
Circulation 110:1754-60. 2004..4%, adjusted P=0.02). We sought to determine whether Canadian-US differences in practice patterns in GUSTO-I had an impact on 5-year mortality...
Impact of different patterns of invasive care on quality of life outcomes in patients with non-ST elevation acute coronary syndrome: results from the GUSTO-IIb Canada-United States substudyPadma Kaul
University of Alberta, Edmonton
Can J Cardiol 20:760-6. 2004....
Ethnic differences in 1-year mortality among patients hospitalised with heart failurePadma Kaul
Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Heart 97:1048-53. 2011..The objective of this study was to examine the impact of ethnicity on 1-year mortality among patients with heart failure in a single payer healthcare system with universal access...
International differences in evolution of early discharge after acute myocardial infarctionPadma Kaul
University of Alberta, Edmonton, Alberta, Canada
Lancet 363:511-7. 2004..We aimed to identify the extent to which countries have taken advantage of the opportunity for early discharge...
Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI) trialRajendra H Mehta
Duke Clinical Research Institute, Durham, NC 27715, USA
Am Heart J 163:797-803. 2012..Information on practice patterns and outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary interventions (PCIs) in Canada vs United States is limited...
Impact of sex on long-term mortality from acute myocardial infarction vs unstable anginaWei-Ching Chang
Department of Medicine, University of Alberta, Edmonton, Canada
Arch Intern Med 163:2476-84. 2003..Additional investigation into the causes, treatment, and policy implications of the age-sex interaction is warranted...
Interinstitutional variation in the use of abciximab for percutaneous coronary interventionCynthia M Westerhout
Department of Public Health Sciences, University of Alberta, Edmonton
Can J Cardiol 20:405-10. 2004..The absence of provincial or national guidelines may have influenced the uptake and application of this novel therapy...
Trends in heart failure care: has the incident diagnosis of heart failure shifted from the hospital to the emergency department and outpatient clinics?Justin A Ezekowitz
Division of Cardiology 2C2 WMC, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
Eur J Heart Fail 13:142-7. 2011..Our objective was to describe the incidence, prevalence, or outcomes for HF patients diagnosed in the outpatient or emergency department (ED) setting...
Resource use in the last 6 months of life among medicare beneficiaries with heart failure, 2000-2007Kathleen T Unroe
Duke Clinical Research Institute, Durham, NC 27715, USA
Arch Intern Med 171:196-203. 2011..Heart failure is a common cause of death among Medicare beneficiaries, but little is known about health care resource use at the end of life...
Effects of socioeconomic status on mortality after acute myocardial infarctionWei Ching Chang
University of Alberta, Edmonton, Alberta, Canada
Am J Med 120:33-9. 2007..To assess the effects of socioeconomic status on mortality in patients with acute myocardial infarction...
Sex differences in patients seeking medical attention for prodromal symptoms before an acute coronary eventMichelle M Graham
Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Am Heart J 156:1210-1216.e1. 2008..We used population-level data to determine the rate at which such patients seek medical attention for these symptoms, whether sex differences are present, and if an association between prodromes and 1-year mortality exists...
Forecasting mortality: dynamic assessment of risk in ST-segment elevation acute myocardial infarctionWei-Ching Chang
Department of Medicine, University of Alberta, 2-51 Medical Sciences Building, Edmonton, Alberta, Canada T6G 2H7
Eur Heart J 27:419-26. 2006..g. the identification of high-risk patients for possible co-interventions. CONCLUSION: Dynamic modelling for STEMI patients enhances the risk assessment and stratification and should provide valuable ongoing guidance for their management...
Predicting the risk of unplanned readmission or death within 30 days of discharge after a heart failure hospitalizationAnita G Au
Division of General Internal Medicine, University of Alberta, Edmonton, Canada
Am Heart J 164:365-72. 2012..The accuracy of current models to predict the risk of unplanned readmission or death after a heart failure (HF) hospitalization is uncertain...
Troponin T and quantitative ST-segment depression offer complementary prognostic information in the risk stratification of acute coronary syndrome patientsPadma Kaul
Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA
J Am Coll Cardiol 41:371-80. 2003..4 vs. 1.5). CONCLUSIONS: Quantitative ST and cTnT status are complementary in assessing risk among ACS patients and both should be employed to determine prognosis and assist in medical decision making...
Poverty, process of care, and outcome in acute coronary syndromesSunil V Rao
Duke Clinical Research Institute, dDuke University, PO Box 17969, Durham, NC 27715, USA
J Am Coll Cardiol 41:1948-54. 2003..We sought to determine whether income-based disparities in care processes and outcome exist in patients with acute coronary syndromes...
Impact of specialist follow-up in outpatients with congestive heart failureJustin A Ezekowitz
Division of Cardiology, University of Alberta, Edmonton, Alta
CMAJ 172:189-94. 2005..Methods to improve timely and appropriate access to specialists and to improve collaborative care structures are needed...
Declining in-hospital mortality and increasing heart failure incidence in elderly patients with first myocardial infarctionJustin A Ezekowitz
Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
J Am Coll Cardiol 53:13-20. 2009..The purpose of this study was to examine the long-term incidence of heart failure (HF) in elderly patients with myocardial infarction (MI)...
Changes in heart failure outcomes after a province-wide change in health service provision a natural experiment in Alberta, CanadaFinlay A McAlister
Divisions of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada
Circ Heart Fail 6:76-82. 2013..The Alberta Cardiac Access (ACA) initiative was implemented in the spring of 2008 to increase access to specialized heart failure (HF) clinics after hospital discharge...
Influence of racial disparities in procedure use on functional status outcomes among patients with coronary artery diseasePadma Kaul
University of Alberta, Edmonton, Alberta, Canada
Circulation 111:1284-90. 2005..Differential use of coronary revascularization may contribute to the poorer functional outcomes observed among black patients with documented coronary disease...
Acute heart failure: perspectives from a randomized trial and a simultaneous registryJustin A Ezekowitz
Mazankowski Alberta Heart Institute and the University of Alberta, Edmonton, AB, Canada
Circ Heart Fail 5:735-41. 2012....
International variation in and factors associated with hospital readmission after myocardial infarctionRobb D Kociol
Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715, USA
JAMA 307:66-74. 2012..Recently, 30-day readmission rates have been proposed as a metric for care of patients with STEMI. However, international rates and predictors of 30-day readmission after STEMI have not been studied...
Acute heart failure in the emergency department: short and long-term outcomes of elderly patients with heart failureJustin A Ezekowitz
Division of Cardiology, Department of Medicine University of Alberta, Canada
Eur J Heart Fail 10:308-14. 2008..We examined discharge rates, and whether outcomes, including mortality, differed based on admission status in AHF...
Recent temporal trends and geographic distribution of cardiac procedures in AlbertaM Sean McMurtry
University of Alberta, Edmonton, Alberta, Canada
Can J Cardiol 29:460-5. 2013..Prior Canadian studies of cardiac procedure rates showed changes over time and regional variability, but more recent Canadian cardiac procedure rates are unknown...
Patterns of care and outcomes differ for urban versus rural patients with newly diagnosed heart failure, even in a universal healthcare systemJohn Michael Gamble
Department of Public Health Sciences, University of Alberta, Edmonton, Canada
Circ Heart Fail 4:317-23. 2011..We aimed to determine whether outcomes differ for patients with incident heart failure (HF) by urban-rural status...
From controlled trials to clinical practice: monitoring transmyocardial revascularization use and outcomesEric D Peterson
Duke Clinical Research Institute, Durham, North Carolina 27710, USA
J Am Coll Cardiol 42:1611-6. 2003..We also identified important risk factors for TMR and compared outcomes of TMR combined with coronary artery bypass graft surgery (TMR + CABG) versus bypass alone in patients receiving incomplete revascularization...
Regional patterns of use of a medical management strategy for patients with non-ST-segment elevation acute coronary syndromes: insights from the EARLY ACS TrialMatthew T Roe
Duke Clinical Research Institute, Durham, NC, USA
Circ Cardiovasc Qual Outcomes 5:205-13. 2012..Regional differences in the profile and prognosis of non-ST-segment elevation acute coronary syndrome (NSTE ACS) patients treated with medical management after angiography remain uncertain...
The epidemiology and management of elderly patients with myocardial infarction or heart failureJustin A Ezekowitz
Division of Cardiology, University of Alberta, 2C2 WMC, 8440 112 Street, Edmonton, Alberta T6G 2B7, Canada
Heart Fail Rev 15:407-13. 2010..Attention to this issue is important when selecting treatment strategies and a focus on the goals of care is critical when decisions for care must be undertaken...
Determining the cost economic "tipping point" for the addition of a regional percutaneous coronary intervention facilityJeffrey A Bakal
Canadian VIGOUR Centre, Edmonton, Alberta, Canada
Can J Cardiol 27:567-72. 2011..A new regional PCI facility could be economically viable if implementation costs are at least comparable to urgent transportation and interventional team clinical competency is maintained...
Electrocardiographic identification of the culprit coronary artery in inferior wall ST elevation myocardial infarctionMohammed Almansori
Division of Cardiology, Department of Medicine, University of Alberta, Alberta, Canada
Can J Cardiol 26:293-6. 2010..In the setting of inferior wall myocardial infarction (IWMI), identification of the right coronary artery (RCA) as the culprit artery is important because of the potential complications associated with its involvement...
Trends in utilization of coronary artery bypass surgery and associated outcomes: Alberta, Manitoba, and Nova ScotiaPadma Kaul
Duke Clinical Research Institute, Duke University, 2400 Pratt Street, Room 0311, Durham, NC 27705, USA
Am J Med Qual 17:103-12. 2002..Whereas ALOS, complications rates, and mortality rates decreased in all provinces over the study period, there was considerable variation in province-specific rates...
Prognostic value of ST segment depression in acute coronary syndromes: insights from PARAGON-A applied to GUSTO-IIb. PARAGON-A and GUSTO IIb Investigators. Platelet IIb/IIIa Antagonism for the Reduction of Acute Global Organization NetworkP Kaul
University of Alberta, Edmonton, Canada
J Am Coll Cardiol 38:64-71. 2001..CONCLUSIONS: These data provide new evidence supporting the powerful prognostic value of the baseline electrocardiogram and, in particular, the magnitude and distribution of ST segment depression in predicting unfavorable events...
Six-month outcomes of percutaneous coronary balloon angioplasty in acute coronary syndromes: Results from the PURSUIT trialMarino Labinaz
University of Ottawa Heart Institute, Ottawa, Ontario
Can J Cardiol 20:773-8. 2004..For patients with ACS undergoing percutaneous balloon angioplasty without coronary stenting in the era of platelet glycoprotein IIb/IIIa blockade, the long-term prognosis is less clear...
Connecting the pieces of the cardiovascular care puzzle in CanadaPadma Kaul
Can J Cardiol 19:1114-5. 2003
Myocardial infarction following coronary artery bypass graft surgery increases healthcare resource utilizationJohn C Chen
Division of Cardiothoracic Surgery, University of Hawaii School of Medicine, Honolulu, USA
Crit Care Med 35:1296-301. 2007..To assess the health economic impact of perioperative myocardial infarction in a cohort of patients undergoing coronary artery bypass graft surgery...
Country specific cost comparisons from multinational clinical trials using empirical Bayesian shrinkage estimation: the Canadian ASSENT-3 economic analysisAndrew R Willan
Program in Population Health Sciences, Sick Kids Research Institute, and Department of Public Health Sciences, University of Toronto, Canada
Health Econ 14:327-38. 2005..The approaches are illustrated and compared using the data from the ASSENT-3 trial...
Cost-effectiveness of cardiac resynchronization therapy in patients with symptomatic heart failureGraham Nichol
University of Washington Harborview Prehospital Emergency Care Research and Training Center and Harborview Medical Center, Seattle, Washington 98104, USA
Ann Intern Med 141:343-51. 2004..Resynchronization of ventricular contraction in patients with heart failure improves ejection fraction. The long-term morbidity and costs associated with such cardiac resynchronization therapy remain unclear...
Charting the course of clinical research: from an inspired past to a promising futurePaul W Armstrong
Am Heart J 148:190-2. 2004
Cost-effectiveness of high-dose atorvastatin compared with usual-dose simvastatin: less than IDEAL?Padma Kaul
Eur Heart J 28:1405-6. 2007
