Rees Kassen

Summary

Affiliation: University of Ottawa
Country: Canada

Publications

  1. ncbi request reprint The ecology and genetics of microbial diversity
    Rees Kassen
    Department of Biology and Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, ON K1N 6N5, Canada
    Annu Rev Microbiol 58:207-31. 2004
  2. ncbi request reprint Ecological constraints on diversification in a model adaptive radiation
    Rees Kassen
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
    Nature 431:984-8. 2004
  3. ncbi request reprint Distribution of fitness effects among beneficial mutations before selection in experimental populations of bacteria
    Rees Kassen
    Department of Biology and Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa K1N 6N5, Canada
    Nat Genet 38:484-8. 2006
  4. pmc Genomics of adaptation during experimental evolution of the opportunistic pathogen Pseudomonas aeruginosa
    Alex Wong
    Department of Biology, Carleton University, Ottawa, Canada
    PLoS Genet 8:e1002928. 2012
  5. pmc Multivariate phenotypic divergence due to the fixation of beneficial mutations in experimentally evolved lineages of a filamentous fungus
    Sijmen E Schoustra
    Department of Biology, University of Ottawa, Ottawa, Ontario, Canada
    PLoS ONE 7:e50305. 2012
  6. doi request reprint The length of adaptive walks is insensitive to starting fitness in Aspergillus nidulans
    Danna R Gifford
    Department of Biology and Centre for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, Canada
    Evolution 65:3070-8. 2011
  7. pmc Antagonistic interactions peak at intermediate genetic distance in clinical and laboratory strains of Pseudomonas aeruginosa
    Sijmen E Schoustra
    Biology Department, University of Ottawa, 30 Marie Curie, Ottawa, ON K1N 6N5, Canada
    BMC Microbiol 12:40. 2012
  8. ncbi request reprint On the experimental evolution of specialization and diversity in heterogeneous environments
    Jean Nicolas Jasmin
    Department of Biology, University of Ottawa and Center for Advanced Research in Environmental Genomics, Ottawa, ON, Canada
    Ecol Lett 10:272-81. 2007
  9. pmc Adaptive divergence in experimental populations of Pseudomonas fluorescens. III. Mutational origins of wrinkly spreader diversity
    Eleni Bantinaki
    Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, United Kingdom
    Genetics 176:441-53. 2007
  10. pmc Evolution of a single niche specialist in variable environments
    Jean Nicolas Jasmin
    Department of Biology and Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, Canada K1N 6N5
    Proc Biol Sci 274:2761-7. 2007

Detail Information

Publications22

  1. ncbi request reprint The ecology and genetics of microbial diversity
    Rees Kassen
    Department of Biology and Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, ON K1N 6N5, Canada
    Annu Rev Microbiol 58:207-31. 2004
    ..We conclude by emphasizing the importance of placing detailed molecular-level studies within the context of a sound ecological and evolutionary framework...
  2. ncbi request reprint Ecological constraints on diversification in a model adaptive radiation
    Rees Kassen
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
    Nature 431:984-8. 2004
    ....
  3. ncbi request reprint Distribution of fitness effects among beneficial mutations before selection in experimental populations of bacteria
    Rees Kassen
    Department of Biology and Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa K1N 6N5, Canada
    Nat Genet 38:484-8. 2006
    ..We also document substantial variation in the pleiotropic costs of antibiotic resistance, a result that may have implications for strategies aimed at eliminating resistant pathogens in animal and human populations...
  4. pmc Genomics of adaptation during experimental evolution of the opportunistic pathogen Pseudomonas aeruginosa
    Alex Wong
    Department of Biology, Carleton University, Ottawa, Canada
    PLoS Genet 8:e1002928. 2012
    ..Experimental evolutionary approaches to understanding pathogen adaptation should provide an important complement to studies of the evolution of clinical isolates...
  5. pmc Multivariate phenotypic divergence due to the fixation of beneficial mutations in experimentally evolved lineages of a filamentous fungus
    Sijmen E Schoustra
    Department of Biology, University of Ottawa, Ottawa, Ontario, Canada
    PLoS ONE 7:e50305. 2012
    ..These results are discussed in the context of the evolution of complex phenotypes through the input of adaptive mutations...
  6. doi request reprint The length of adaptive walks is insensitive to starting fitness in Aspergillus nidulans
    Danna R Gifford
    Department of Biology and Centre for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, Canada
    Evolution 65:3070-8. 2011
    ..Our results suggest that the length of adaptive walks may be independent of the fitness of the founding genotype and, moreover, that poorly adapted populations can quickly adapt to novel environments...
  7. pmc Antagonistic interactions peak at intermediate genetic distance in clinical and laboratory strains of Pseudomonas aeruginosa
    Sijmen E Schoustra
    Biology Department, University of Ottawa, 30 Marie Curie, Ottawa, ON K1N 6N5, Canada
    BMC Microbiol 12:40. 2012
    ..The strength of antagonism is therefore expected to peak at intermediate genetic distance...
  8. ncbi request reprint On the experimental evolution of specialization and diversity in heterogeneous environments
    Jean Nicolas Jasmin
    Department of Biology, University of Ottawa and Center for Advanced Research in Environmental Genomics, Ottawa, ON, Canada
    Ecol Lett 10:272-81. 2007
    ..The results provide general support for this interpretation of the environmental variance and suggest further that competition among genotypes promotes diversification in heterogeneous environments...
  9. pmc Adaptive divergence in experimental populations of Pseudomonas fluorescens. III. Mutational origins of wrinkly spreader diversity
    Eleni Bantinaki
    Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, United Kingdom
    Genetics 176:441-53. 2007
    ..Remarkably, different mutations have different phenotypic and fitness effects. We suggest that the negative feedback loop inherent in Wsp regulation allows the pathway to be tuned by mutation in a rheostat-like manner...
  10. pmc Evolution of a single niche specialist in variable environments
    Jean Nicolas Jasmin
    Department of Biology and Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, Canada K1N 6N5
    Proc Biol Sci 274:2761-7. 2007
    ..We provide evidence to suggest that our results reflect a novel constraint on niche evolution imposed by the supply of beneficial mutations available to selection in variable environments...
  11. doi request reprint Adaptive landscapes in evolving populations of Pseudomonas fluorescens
    Anita H Melnyk
    Department of Biology and Centre for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, Canada
    Evolution 65:3048-59. 2011
    ..Our study demonstrates the utility of using replicate selection lines with different evolutionary starting points to try and quantify the relative ruggedness of adaptive landscapes...
  12. ncbi request reprint The effects of competition and predation on diversification in a model adaptive radiation
    Justin R Meyer
    Department of Biology and Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa K1N 6N5, Canada
    Nature 446:432-5. 2007
    ..The cause of this delay stems from weaker diversifying selection due to the reduction in prey density caused by predation. Our results suggest that predation may play an under-appreciated role in driving adaptive radiations...
  13. doi request reprint Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa
    Jeremy R Dettman
    Department of Biology, Centre for Advanced Research in Environmental Genomics, and Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada K1N 6N5
    Proc Natl Acad Sci U S A 110:21065-70. 2013
    ..Multiple lines of evidence suggest that selection imposed by the CF lung environment has a major influence on genomic evolution and the genetic characteristics of P. aeruginosa isolates causing contemporary infection. ..
  14. pmc Competition both drives and impedes diversification in a model adaptive radiation
    Susan F Bailey
    Department of Biology, University of Ottawa, 30 Marie Curie Private, Ottawa, Ontario, Canada
    Proc Biol Sci 280:20131253. 2013
    ..These results suggest that the progress of an adaptive radiation depends ultimately on the strength of resource competition, an effect that can be exaggerated or impeded by the presence of competitors. ..
  15. doi request reprint Spatial structure of ecological opportunity drives adaptation in a bacterium
    Susan F Bailey
    Department of Biology and Centre for Advanced Research in Environmental Genomics, University of Ottawa, Ontario K1N 6N5, Canada
    Am Nat 180:270-83. 2012
    ..Instead, we saw the evolution of a single adaptive strategy that differed with respect to phenotype and degree of specialization, depending on both the extent and the spatial structure of ecological opportunity...
  16. doi request reprint Evolutionary insight from whole-genome sequencing of experimentally evolved microbes
    Jeremy R Dettman
    Department of Biology and Centre for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, ON K1N 6N5, Canada
    Mol Ecol 21:2058-77. 2012
    ..We also outline an example of a computational pipeline for use in EE-WGS studies, based on freely available bioinformatics tools...
  17. pmc The properties of adaptive walks in evolving populations of fungus
    Sijmen E Schoustra
    Department of Biology, University of Ottawa, Ottawa, Ontario, Canada
    PLoS Biol 7:e1000250. 2009
    ..In practical terms, our results suggest that the bulk of adaptation is likely to be accomplished within the first few steps...
  18. doi request reprint Toward a general theory of adaptive radiation: insights from microbial experimental evolution
    Rees Kassen
    Department of Biology and Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, Canada
    Ann N Y Acad Sci 1168:3-22. 2009
    ....
  19. doi request reprint Fitness-associated sexual reproduction in a filamentous fungus
    Sijmen Schoustra
    Department of Biology, Center for Applied Research in Environmental Genomics, University of Ottawa, 30 Marie Curie, Ottawa, Ontario, Canada
    Curr Biol 20:1350-5. 2010
    ..FAS in A. nidulans is unlikely to have evolved as a strategy to resist or avoid stress because asexual spores are more dispersive and equally resistant [12, 13]...
  20. ncbi request reprint Evolutionary stable investment in products that confer both an individual benefit and a public good
    Tom N Sherratt
    Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON K1S 5B6, Canada
    Front Biosci (Landmark Ed) 14:4557-64. 2009
    ..Overall, this "personal gain" approach offers a simple yet robust explanation for why individuals engage in activities which may concomitantly benefit others...
  21. doi request reprint Parallel evolution and local differentiation in quinolone resistance in Pseudomonas aeruginosa
    Alex Wong
    Center for Advanced Research in Environmental Genomics, Department of Biology, University of Ottawa, Ottawa, ON, Canada
    Microbiology 157:937-44. 2011
    ..We further discuss the therapeutic implications of local differentiation in resistance mechanisms to a common antibiotic...
  22. pmc Global analysis of predicted proteomes: functional adaptation of physical properties
    Christopher G Knight
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, United Kingdom
    Proc Natl Acad Sci U S A 101:8390-5. 2004
    ..This relationship is not adequately explained by AT bias at the DNA sequence level. Together, these data provide evidence of functional adaptation in the properties of complete proteomes...